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Effect of Levothyroxine Replacement on Lipid Profile and Intima-Media Thickness in Subclinical Hypothyroidism: A Double-Blind, Placebo- Controlled Study
Abstract
Subclinical hypothyroidism (sHT) is associated with dyslipidemia and enhanced cardiovascular risk. We assessed carotid artery intima-media thickness (IMT, high-resolution ultrasonography) and lipoprotein profile in 45 sHT patients (aged 37 +/- 11 yr) at baseline and after 6 months of randomized, placebo-controlled L-T(4) replacement. In comparison with 32 age- and sex-matched controls, sHT patients had elevated total and low-density lipoprotein (LDL) cholesterol and ApoB levels (P = 0.002, P = 0.0007, and P = 0.01, respectively) and higher mean-IMT values (P < 0.0001). In stepwise regression analysis, mean-IMT was positively related (r(2) = 0.71, P < 0.0001) to age, TSH, and LDL cholesterol. L-T(4) replacement significantly reduced both total and LDL cholesterol (P < 0.0001 for both) and mean-IMT (by 11%, P < 0.0001). The decrement in IMT was directly related to the decrements of both total cholesterol and TSH (P = 0.02 and P = 0.0001, respectively). We conclude that early carotid artery wall alterations are present in sHT patients. Whether such IMT increase is related to an early atherosclerotic involvement of the arterial wall cannot be clearly decided on the basis of the present results. However, the fact that L-T(4) replacement therapy was able to improve both the atherogenic lipoprotein profile and intima-media thickening suggests that lipid infiltration of arterial wall may represent a major mechanism underlying IMT increase in subclinical hypothyroidism.
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“The results of RCTs have indicated that cholesterol (50,82-86), and SHBG levels (50) are particularly affected by the administration of LT4.”
From Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (2014) · cites this paper as [83]
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“The most frequent cardiac abnormality observed in SCH is diastolic dysfunction due to impaired ventricular filling and relaxation (90,91).”
From Thyroid Hormones and Cardiovascular Function and Diseases (2018) · cites this paper as [90]
Citations
Cites
The Colorado Thyroid Disease Prevalence Study
Canaris, G. J., Manowitz, N. R., Mayor, G., & Ridgway, E. C. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.4.526 · Cited by 2,824
THE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY
Tunbridge, W. M. G., Evered, D. C., Hall, R., Appleton, D. R., BREWIS, M., CLARK, F., Evans, J. G., Young, E. T., Bird, T., & Smith, P. (1977) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1977.tb01340.x · Cited by 2,665
Common Carotid Intima-Media Thickness and Risk of Stroke and Myocardial Infarction
Bots, M. L., Hoes, A. W., Koudstaal, P. J., Albert Hofman, D., & Grobbee, D. E. (1997) · Circulation · doi:10.1161/01.cir.96.5.1432 · Cited by 2,333
Thyroid hormone and the cardiovascular system.
Klein, I., & Ojamaa, K. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102153440707 · Cited by 2,300
Hak, A. E., Pols, H. A. P., Visser, T. J., Drexhage, H. A., Hofman, A., & Witteman, J. C. M. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-132-4-200002150-00004 · Cited by 1,336
Law, M., Wald, N., & Thompson, S. (1994) · British medical journal · doi:10.1136/bmj.308.6925.367 · Cited by 1,306
Boerwinkle, E., Leffert, C. C., Lin, J., Lackner, C., Chiesa, G., & Hobbs, H. H. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115855 · Cited by 973
Lipid Alterations and Decline in the Incidence of Coronary Heart Disease in the Helsinki Heart Study
Manninen, V. (1988) · JAMA · doi:10.1001/jama.1988.03410050061031 · Cited by 954
Arterial Wall Thickness Is Associated With Prevalent Cardiovascular Disease in Middle-Aged Adults
Burke, G. L., Evans, G. W., Riley, W. A., Sharrett, A. R., Howard, G., Barnes, R. W., Rosamond, W. D., Crow, R. S., Rautaharju, P. M., & HEISS, G. M. (1995) · Stroke · doi:10.1161/01.str.26.3.386 · Cited by 897
HEISS, G. M., Sharrett, A. R., Barnes, R. W., Chambless, L. E., Szklo, M., & Alzola, C. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116078 · Cited by 838
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Items 101–200 of 398
Effect of levothyroxine replacement on exercise performance in subclinical hypothyroidism
Mainenti, M. R. M., Vigário, P. D. S., Teixeira, P. D. F. D. S., Maia, M., Oliveira, F. P., & Vaisman, M. (2009) · Journal of Endocrinological Investigation · doi:10.1007/bf03346488 · Cited by 47
Nagasaki, T., Inaba, M., Yamada, S., Shirakawa, K., Nagata, Y., Kumeda, Y., Hiura, Y., Tahara, H., Ishimura, E., & Nishizawà, Y. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0742 · Cited by 47
Topaloğlu, O., Gökay, F., Küçükler, K., BURNİK, F. S., Mete, T., Yavuz, H. C., Berker, D. S., & Güler, S. (2012) · Endocrine · doi:10.1007/s12020-012-9842-5 · Cited by 46
Kowalska, I., Borawski, J., Nikołajuk, A., Budlewski, T., Otziomek, E., Górska, M., & Strączkowski, M. (2011) · Endocrine · doi:10.1007/s12020-011-9446-5 · Cited by 46
Thyroid disease and the nervous system
Wood-Allum, C. A., & Shaw, P. J. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-7020-4087-0.00048-6 · Cited by 45
Subclinical hypothyroidism and vascular risk: An update
Lioudaki, E., Mavroeidi, N., Mikhailidis, D. P., & Ganotakis, E. S. (2013) · HORMONES · doi:10.14310/horm.2002.1437 · Cited by 45
Ünal, E., Akın, A., Yıldırım, R., Demir, V., Yıldız, İ., & Haspolat, Y. K. (2016) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.3719 · Cited by 45
Hamano, K., & Inoue, M. (2005) · Endocrine Journal · doi:10.1507/endocrj.52.95 · Cited by 44
Endothelial Function in Patients with Subclinical Hypothyroidism: A Meta-Analysis
Gong, N., Gao, C., Chen, X., Fang, Y., & Tian, L. (2019) · Hormone and Metabolic Research · doi:10.1055/a-1018-9564 · Cited by 46
Endocrine late effects from multi-modality treatment of neuroblastoma
van Santen, H. M., de Kraker, J., & Vulsma, T. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2005.02.036 · Cited by 42
Ye, Y., Xie, H., Zeng, Y., Zhao, X., Tian, Z., & Zhang, S. (2013) · Endocrine Practice · doi:10.4158/ep13237.or · Cited by 42
Metabolic cardiovascular disease risk factors and their clustering in subclinical hypothyroidism
Ashizawa, K., Imaizumi, M., Usa, T., Tominaga, T., Sera, N., Hida, A., Ejima, E., Neriishi, K., Soda, M., Ichimaru, S., et al. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03697.x · Cited by 44
Kim, E. S., Shin, J. A., Shin, J. Y., Lim, D. J., Moon, S. D., Son, H., & Han, J. H. (2012) · Thyroid · doi:10.1089/thy.2011.0366 · Cited by 41
Update on subclinical thyroid dysfunction
Hashimoto, K. (2022) · Endocrine Journal · doi:10.1507/endocrj.ej22-0182 · Cited by 44
Nonthyroidal illness and the cardiorenal syndrome
Meuwese, C. L., Dekkers, O. M., Stenvinkel, P., Dekker, F. W., & Carrero, J. J. (2013) · Nature Reviews Nephrology · doi:10.1038/nrneph.2013.170 · Cited by 39
Multi-center study on the prevalence of hypothyroidism in patients with hypercholesterolemia
Tagami, T., Kimura, H., Ohtani, S., Tanaka, T., Tanaka, T., Hata, S., Saito, M. H., Miyazaki, Y., Araki, R., Tanaka, M., et al. (2011) · Endocrine Journal · doi:10.1507/endocrj.k11e-012 · Cited by 39
Yao, K., Zhao, T., Zeng, L., Yang, J., Liu, Y., He, Q., & Zou, X. (2018) · Scientific Reports · doi:10.1038/s41598-018-22897-3 · Cited by 38
Thyroid Dysfunction and Atherosclerosis: A Systematic Review
Παπαδοπούλου, Ά.-Μ., Bakogiannis, N., Skrapari, I. C., Moris, D., & Bakoyiannis, C. N. (2020) · In Vivo · doi:10.21873/invivo.12147 · Cited by 39
Evaluation of epicardial fat tissue thickness in patients with H ashimoto thyroiditis
Aşık, M., Şahin, S., Özkul, F., Anaforoğlu, İ., Ayhan, S., Karagol, S., Güneş, F., & Algün, E. (2013) · Clinical Endocrinology · doi:10.1111/cen.12176 · Cited by 39
Herter‐Aeberli, I., Cherkaoui, M., Ansari, N. E., Rohner, R., Stinca, S., Chabaa, L., von Eckardstein, A., Aboussad, A., & Zimmermann, M. B. (2015) · Journal of Nutrition · doi:10.3945/jn.115.213439 · Cited by 38
Effect of l-thyroxine treatment on left ventricular function in subclinical hypothyroidism
Franzoni, F., Galetta, F., Fallahi, P., Tocchini, L., Merico, G., Braccini, L., Rossi, M., Carpi, A., Antonelli, A., & Santoro, G. (2006) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2006.07.010 · Cited by 39
Overt and ???Subclinical??? Hypothyroidism in Women
Wartofsky, L., Nostrand, D. V., & Burman, K. D. (2006) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000228778.95752.66 · Cited by 38
Cabral, M. D., Teixeira, P., Soares, D. V., Leite, I. S., Salles, E. F., & Waisman, M. (2011) · Clinics · doi:10.1590/s1807-59322011000800003 · Cited by 38
He, W., Li, S., Zhang, J., Zhang, J., Mu, K., & Li, X. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00454 · Cited by 37
Relationship of thyroid stimulating hormone with coronary atherosclerosis in angina patients
Yun, K. H., Jeong, M. H., Oh, S. K., Lee, E. M., Lee, J., Rhee, S. J., Yoo, N. J., Kim, N., Ahn, Y. K., & Jeong, J. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.11.039 · Cited by 37
Endothelial dysfunction and the risk of atherosclerosis in overt and subclinical hypothyroidism
Saif, A., Mousa, S., Assem, M., Tharwat, N., & Abdelhamid, A. (2018) · Endocrine Connections · doi:10.1530/ec-18-0194 · Cited by 36
Chiche, F., Jublanc, C., Coudert, M., Carreau, V., Kahn, J.-F., & Bruckert, É. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.06.011 · Cited by 36
Anagnostis, P. G., Efstathiadou, Z. A., Slavakis, A., Selalmatzidou, D., Poulasouchidou, M., Katergari, S., Karathanasi, E. M., Dogramatzi, F., & Kita, M. D. (2014) · International Journal of Clinical Practice · doi:10.1111/ijcp.12394 · Cited by 36
Duggal, J., Singh, S., Barsano, C. P., & Arora, R. R. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.06583.x · Cited by 36
Does Treating Subclinical Hypothyroidism Improve Markers of Cardiovascular Risk?
Monzani, F., Dardano, A., & Caraccio, N. (2006) · Treatments in Endocrinology · doi:10.2165/00024677-200605020-00001 · Cited by 37
Self-citationSalerno, M., Oliviero, U., Lettiero, T., Guardasole, V., Mattiacci, D. M., Saldamarco, L., Capalbo, D., Lucariello, A., Saccà, L., & Cittadini, A. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2315 · Cited by 35
Thyroid function and ischemic heart disease: a Mendelian randomization study
Zhao, J. V., & Schooling, C. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-07592-z · Cited by 34
Endothelial dysfunction and subclinical hypothyroidism: a brief review.
Vignera, S. L., Condorelli, R. A., Vicari, E. S. D., & Calogero, A. E. (2012) · PubMed · doi:10.3275/8190 · Cited by 35
Zimmermann, M. B., Herter‐Aeberli, I., Melse‐Boonstra, A., Grimci, L., Bridson, J., Chaouki, N., Mbhenyane, X. G., & Jooste, P. L. (2009) · Thyroid · doi:10.1089/thy.2009.0001 · Cited by 35
Niknam, N., Khalili, N., Khosravi, E., & Nourbakhsh, M. (2016) · Advanced Biomedical Research · doi:10.4103/2277-9175.178783 · Cited by 34
Pesic, M. M., Radojković, D., Antić, S., Kocić, R., & Stankovic‐Djordjevic, D. (2014) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2014.991136 · Cited by 33
Yang, G.-R., Yang, J., Zhang, L., An, Y.-H., & Lu, J.-K. (2010) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.222.303 · Cited by 34
Sert, A., Pirgon, Ö., Aypar, E., Yılmaz, H. S., & Odabaş, D. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0638-z · Cited by 33
Hypothyroidism and Cardiovascular Disease: A Review
Zúñiga, D., Balasubramanian, S., Mehmood, K. T., AL-Baldawi, S. A. A., & Salazar, G. Z. (2024) · Cureus · doi:10.7759/cureus.52512 · Cited by 46
Cerit, E. T., Aktürk, M., Altınova, A. E., Tavıl, Y., Özkan, Ç., Yayla, Ç., Altay, M., Demirtas, C., & Çakır, N. (2014) · Endocrine · doi:10.1007/s12020-014-0460-2 · Cited by 31
Cabral, M. D., Teixeira, P. D. F. D. S., Silva, N. A. O., de Morais, F. F. C., Soares, D. V., Salles, E. F., Henriques, J. M., Leite, S. P., Montenegro, C. A. B., & Vaisman, M. (2009) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2009000500005 · Cited by 33
Tirabassi, G., Muti, N. D., Corona, G., Maggi, M., & Balercia, G. (2013) · International Journal of Endocrinology · doi:10.1155/2013/816740 · Cited by 31
Subclinical Hypothyroidism: Frequency, clinical presentations and treatment indications
Khan, M. A., Ahsan, T., Rehman, U. L., Jabeen, R., & Farouq, S. (2017) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.334.12921 · Cited by 32
Hypothyroidism: Cardiovascular Endpoints of Thyroid Hormone Replacement
Stamatouli, A. M., Bedoya, P., & Yavuz, S. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00888 · Cited by 34
Hashimoto Thyroiditis and Dyslipidemia in Childhood: A Review
Vuković, R., Zeljković, A., Bufan, B., Spasojević‐Kalimanovska, V., Milenković, T., & Vekić, J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00868 · Cited by 33
High prevalence of subclinical hypothyroidism in patients with Anderson–Fabry disease
Hauser, A., Gessl, A., Lorenz, M., Voigtländer, T., Födinger, M., & Sunder–Plassmann, G. (2004) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-005-0003-3 · Cited by 30
Masood, S., Masood, O., Mujtaba, S. F., & Banerjee, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-4723-8_4 · Cited by 31
Recommendation on screening adults for asymptomatic thyroid dysfunction in primary care
Birtwhistle, R., Morissette, K., Dickinson, J. A., Reynolds, D. L., Avey, M. T., Domingo, F. R., Rodin, R., & Thombs, B. D. (2019) · Canadian Medical Association Journal · doi:10.1503/cmaj.190395 · Cited by 36
Gluvic, Z. M., Sudar-Milovanovic, E. M., Tica, J., Jovanović, A., Zafirovic, S. S., Tomašević, R., & Isenović, E. R. (2015) · International Journal of Endocrinology · doi:10.1155/2015/147070 · Cited by 30
Westerink, J., van der Graaf, Y., Faber, D. R., Spiering, W., & Visseren, F. L. J. (2011) · European Journal of Preventive Cardiology · doi:10.1177/1741826711416045 · Cited by 29
Association of Thyroid-stimulating Hormone and Cardiovascular Risk Factors
Sun, X., Sun, Y., Li, W., Chen, C.-Y., Chiu, Y.-H., Chien, H.-Y., & Wang, Y. (2015) · Internal Medicine · doi:10.2169/internalmedicine.54.4514 · Cited by 29
Thyroid hormones and diabetic nephropathy: An essential relationship to recognize
Han, Q., Zhang, J., Wang, Y., Li, H., Zhang, R., Guo, R., Li, L., Teng, G., Wang, J., Wang, T., et al. (2018) · Nephrology · doi:10.1111/nep.13388 · Cited by 30
Oliviero, U., Cittadini, A., Bosso, G., Cerbone, M., Valvano, A., Capalbo, D., Apuzzi, V., Calabrese, F., Lettiero, T., & Salerno, M. (2010) · European Journal of Endocrinology · doi:10.1530/eje-09-0674 · Cited by 27
The debate on treating subclinical hypothyroidism
Tan, E. (2016) · Singapore Medical Journal · doi:10.11622/smedj.2016165 · Cited by 29
Pandrc, M. S., Ristić, A., Kostovski, V., Stanković, M., Antić, V., Milin-Lazovic, J. S., & Ćirić, J. (2017) · Journal of Medical Biochemistry · doi:10.1515/jomb-2017-0007 · Cited by 27
Duman, D., Demirtunç, R., Şahin, S., & Esertas, K. (2007) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e3282f03bc1 · Cited by 27
Clausen, P., Mersebach, H., Nielsen, B., Feldt‐Rasmussen, B., & Feldt‐Rasmussen, U. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03410.x · Cited by 27
Effects of thyroxine replacement on lipid profile and endothelial function after thyroidectomy
Erbil, Y., Özbey, N., Giriş, M., Salmaslıoğlu, A., Özarmağan, S., & Tezelman, S. (2007) · British journal of surgery · doi:10.1002/bjs.5915 · Cited by 27
You, A. S., Sim, J. J., Kovesdy, C. P., Streja, E., Nguyen, D. V., Brent, G. A., Kalantar‐Zadeh, K., & Rhee, C. M. (2018) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfy289 · Cited by 26
Levothyroxine therapy for hypothyroidism: should we abandon conservative dosage titration?
Wartofsky, L. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.15.1683 · Cited by 23
Prevalence of Subclinical Hypothyroidism among Patients with Acute Myocardial Infarction
Okuyan, E., Uslu, A., Asim, E., Gulcin, H. E., Ayça, B., Avşar, M., Sezai, Y. S., Biter, H. İ., & Hakan, D. M. (2011) · ISRN Endocrinology · doi:10.5402/2011/810251 · Cited by 25
Thyroid Disorders in Chronic Heart Failure: From Prognostic Set-up to Therapeutic Management
Triggiani, V., & Iacoviello, M. (2013) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530311313010005 · Cited by 25
Jorde, R., Joakimsen, O., Stensland, E., & Mathiesen, E. B. (2007) · Thyroid · doi:10.1089/thy.2007.0165 · Cited by 25
Subclinical hypothyroidism: Controversies to consensus
Raza, S., & Mahmood, N. (2013) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.123555 · Cited by 25
Subclinical Hypothyroidism and Cardiovascular Risk: How to End the Controversy
Rodondi, N., & Bauer, D. C. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1875 · Cited by 25
Variation of total serum cholesterol among the patient with thyroid dysfunction
Risal, P., Maharjan, B., Koju, R., Makaju, R., & Gautem, M. (1970) · Kathmandu University Medical Journal · doi:10.3126/kumj.v8i2.3573 · Cited by 24
Lombardi, C. P., Bocale, R., Barini, A., Barini, A., D’Amore, A., Boscherini, M., & Bellantone, R. (2017) · Endocrine · doi:10.1007/s12020-016-1003-9 · Cited by 23
Alomair, B. M., Al-Kuraishy, H. M., Al-Gareeb, A. I., Alshammari, M. A., Alexiou, A. T., Papadakis, M., Saad, . M., & Batiha, G. E. (2024) · Thyroid Research · doi:10.1186/s13044-024-00199-3 · Cited by 25
Cardiovascular Risk and Quality of Life in Elderly People with Mild Thyroid Hormone Deficiency
Tognini, S., Pasqualetti, G., Calsolaro, V., Polini, A., Caraccio, N., & Monzani, F. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00153 · Cited by 23
Self-citationAdamarczuk-Janczyszyn, M., Zdrojowy-Wełna, A., Rogala, N., Zatońska, K., & Bednarek-Tupikowska, G. (2016) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/38555 · Cited by 23
Subclinical thyroid dysfunction and risk of carotid atherosclerosis
Kim, H., Kim, T. H., Kim, H. I., Park, S. Y., Kim, Y. N., Kim, S., Kim, M., Jin, S., Hur, K. Y., Kim, J. H., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0182090 · Cited by 23
Neves, J. S., Vale, C., von Hafe, M., Borges‐Canha, M., Leite, A. R., Almeida‐Coelho, J., Lourenço, A. P., Falcão‐Pires, I., Carvalho, D. M., & Leite-Moreira, A. F. (2020) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018820958331 · Cited by 26
Ling, Y., Jiang, J., Gui, M., Liu, L., Aleteng, Q., Wu, B., Wang, S., Liu, X., & Gao, X. (2015) · International Journal of Endocrinology · doi:10.1155/2015/708272 · Cited by 22
Głowińska‐Olszewska, B., Borysewicz-Sańczyk, H., Sawicka, B., Klonowska, B., Charemska, D., Żelazowska‐Rutkowska, B., & Bossowski, A. T. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00431 · Cited by 25
Waterhouse, D. F., McLaughlin, A. M., Walsh, C., Sheehan, F., & O'Shea, D. B. (2007) · Thyroid · doi:10.1089/thy.2006.0208 · Cited by 22
Akbaba, G., Berker, D. S., Işık, S., Tuna, M. M., Koparal, S., Vural, M., Yılmaz, F. M., Topçuoğlu, C., & Güler, S. (2015) · Wiener klinische Wochenschrift · doi:10.1007/s00508-015-0865-9 · Cited by 22
Subclinical hypothyroidism as an independent risk factor for colorectal neoplasm
Mu, G., Mu, X., Xing, H.-Z., Xu, R., Sun, G., Dong, C., Pan, Q., & Xu, C. (2014) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2014.08.002 · Cited by 21
Noninvasive indicators of atherosclerosis in subclinical hypothyroidism
Kılıç, İ. D., Tanriverdi, H. I., Fenkçi, S. M., Akın, F., Uslu, S., & Kaftan, A. (2013) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.109708 · Cited by 21
Giusti, M., Mortara, L., Degrandi, R., Cecoli, F., Mussap, M., Rodriguez, G., Ferone, D., & Minuto, F. M. (2008) · Thyroid Research · doi:10.1186/1756-6614-1-2 · Cited by 21
Relation of Low T3 to One-Year Mortality in Non-ST-Elevation Acute Coronary Syndrome Patients
Yazıcı, S., Kırış, T., Ceylan, U. S., Terzi, S., Erdem, A., Atasoy, I., Emre, A., & YEŞİLÇİMEN, K. (2016) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22036 · Cited by 21
The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis
Yetkin, D. Ö., & Doğantekin, B. (2015) · International Journal of Endocrinology · doi:10.1155/2015/952729 · Cited by 20
Subclinical Hypothyroidism and Cardiovascular Risk
Weiss, I. A., Bloomgarden, N. A., & Frishman, W. H. (2011) · Cardiology in Review · doi:10.1097/crd.0b013e318227df87 · Cited by 20
Nagasaki, T., Inaba, M., Yamada, S., Kumeda, Y., Hiura, Y., & Nishizawà, Y. (2007) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2007.04.004 · Cited by 20
Domingo, F. R., Avey, M. T., & Doull, M. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1181-7 · Cited by 19
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Hassan, A. H., Altamirano-Ufion, A., Zulfiqar, B., & Boddu, P. C. (2017) · Cardiology Research · doi:10.14740/cr524w · Cited by 18
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Zhou, Y., Zhao, L., Wang, T., Hong, J., Zhang, J., Xu, B., Huang, X., Xu, M., & Bi, Y. (2015) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.30338 · Cited by 18
Yazıcı, D., Özben, B., Toprak, A. C., Yavuz, D. G., Aydın, H., Tarçın, Ö., Deyneli, O., & Akalın, S. (2014) · Endocrine · doi:10.1007/s12020-014-0372-1 · Cited by 18
Ostadrahimi, A., Manzari, T., Gohari-Lasaki, S., Tutunchi, H., Mobasseri, M., Sadra, V., & Najafipour, F. (2023) · BMC Research Notes · doi:10.1186/s13104-023-06516-7 · Cited by 17
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Ku, E. J., Yoo, W. S., & Chung, H. K. (2023) · Endocrinology and Metabolism · doi:10.3803/enm.2023.1778 · Cited by 21
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Darouei, B., Amani‐Beni, R., Abhari, A. P., Fakhrolmobasheri, M., Shafie, D., & Heidarpour, M. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.102204 · Cited by 15
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Ha, J., Lee, J., Jo, K., Han, J., Kim, M., Jung, C. K., Kang, M. I., Cha, B., & Lim, D. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7080183 · Cited by 17
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Huang, C., Wei, J. C., Chien, T.-C., Kuo, C.-W., Lin, S.-H., Su, Y., Hsu, C. Y., Chiou, J., & Yeh, M.-H. (2020) · Endocrine Practice · doi:10.1016/j.eprac.2020.09.007 · Cited by 15
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Metadata
- Authors
- Monzani, F., Caraccio, N., Kozàkowà, M., Dardano, A., Vittone, F., Virdis, A., Taddei, S., Palombo, C., & Ferrannini, E.
- Affiliations
- University of Pisa (IT)
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2004-05
- Volume
- 89
- Issue
- 5
- Pages
- 2099-2106
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2068309857
- Cited by
- 399
- References
- 48
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 17 · 2023: 6 · 2022: 12 · 2021: 11 · 2020: 24 · 2019: 17 · 2018: 30 · 2017: 28 · 2016: 21 · 2015: 15 · 2014: 27 · 2013: 29 · 2012: 20
- FWCI
- 13.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutial research information system (University of Pisa) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Keywords
- subclinical hypothyroidism, levothyroxine replacement, lipid profile, LDL cholesterol, apolipoprotein B, intima-media thickness, carotid artery, dyslipidemia, atherosclerosis, thyroid-stimulating hormone, cardiovascular risk
- MeSH terms
- Adult, Cholesterol, Double-Blind Method, Female, Humans, Hypothyroidism, Lipids, Cholesterol, LDL, Male, Middle Aged, Placebos, Regression Analysis, Thyrotropin, Thyroxine, Ultrasonography, Tunica Intima, Tunica Media
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