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Sex Differences of Endogenous Sex Hormones and Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis

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Utility, Limitations, and Pitfalls in Measuring Testosterone: An Endocrine Society Position Statement

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A Guttman Health Scale for the Aged

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Testosterone dose-response relationships in healthy young men

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Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.

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Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study

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Testosterone and Sex Hormone–Binding Globulin Predict the Metabolic Syndrome and Diabetes in Middle-Aged Men

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The third generation cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination

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APHRODITE criteria: addressing male patients with hypogonadism and/or infertility owing to altered idiopathic testicular function

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Human reproductive behavior, life history, and the Challenge Hypothesis: A 30-year review, retrospective and future directions

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The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study

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Sexual incentive motivation, sexual behavior, and general arousal: Do rats and humans tell the same story?

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How to help the aging male? Current approaches to hypogonadism in primary care

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Recalibrating Interpretations of Aldosterone Assays Across the Physiologic Range: Immunoassay and Liquid Chromatography–Tandem Mass Spectrometry Measurements Under Multiple Controlled Conditions

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Symptomatic response to testosterone treatment in dieting obese men with low testosterone levels in a randomized, placebo-controlled clinical trial

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Reference ranges of 17-hydroxyprogesterone, DHEA, DHEAS, androstenedione, total and free testosterone determined by TurboFlow-LC–MS/MS and associations to health markers in 304 men

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Testosterone replacement therapy does not promote priapism in hypogonadal men with sickle cell disease: 12‐month safety report

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Androgens show sex-dependent differences in myelination in immune and non-immune murine models of CNS demyelination

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Association between 25(OH)-vitamin D and testosterone levels: Evidence from men with chronic spinal cord injury

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Relation between Sex Hormone Concentrations, Peripheral Arterial Disease, and Change in Ankle-Brachial Index: Findings from the Framingham Heart Study

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Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women

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Late-onset Hypogonadism and Testosterone Therapy – A Summary of Guidelines from the American Urological Association and the European Association of Urology

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Elderly men over 65 years of age with late-onset hypogonadism benefit as much from testosterone treatment as do younger men

Saad, F., Yassin, A. A., Haider, A., Doros, G. D., & Gooren, L. J. (2015) · Korean journal of urology · doi:10.4111/kju.2015.56.4.310 · Cited by 36

Distribution of Salivary Testosterone in Men and Women in a British General Population-Based Sample: The Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)

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Oral glucose load and mixed meal feeding lowers testosterone levels in healthy eugonadal men

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Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer

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The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism

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Determination of anabolic steroids in dried blood using microsampling and gas chromatography-tandem mass spectrometry: Application to a testosterone gel administration study

Chang, C., Cowan, D., Walker, C. J., Wojek, N., & Brailsford, A. D. (2020) · Journal of Chromatography A · doi:10.1016/j.chroma.2020.461445 · Cited by 34

Determinants of testosterone recovery after bariatric surgery: is it only a matter of reduction of body mass index?

Luconi, M., Samavat, J., Seghieri, G., Iannuzzi, G., Lucchese, M., Rotella, C. M., Forti, G., Maggi, M., & Mannucci, E. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.02.039 · Cited by 33

Longitudinal and Cross-Sectional Relationships of Circulating Reproductive Hormone Levels to Self-Rated Health and Health-Related Quality of Life in Community-Dwelling Older Men

Hsu, B., Cumming, R. G., Blyth, F., Naganathan, V., Couteur, D. G. L., Seibel, M. J., Waite, L. M., & Handelsman, D. J. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3984 · Cited by 33

Circulating Estrone Levels Are Associated Prospectively With Diabetes Risk in Men of the Framingham Heart Study

Jasuja, G. K., Travison, T. G., Davda, M. N., Rose, A. J., Zhang, A., Kushnir, M. M., Rockwood, A. L., Meikle, W. A., Coviello, A. D., D’Agostino, R. B., et al. (2013) · Diabetes Care · doi:10.2337/dc12-2477 · Cited by 32

Functional Voice Testing Detects Early Changes in Vocal Pitch in Women During Testosterone Administration

Huang, G. T.-W., Pencina, K. M., Coady, J. A., Beleva, Y. M., Bhasin, S., & Basaria, S. S. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-1669 · Cited by 32

Sex-Specific Associations of Testosterone With Metabolic Traits

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The applications of androgen in the treatment of dry eye disease: a systematic review of clinical studies

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Normative Basal Values of Hormones and Proteins of Gonadal and Adrenal Functions from Birth to Adulthood

Fanelli, F., Baronio, F., Ortolano, R., Mezzullo, M., Cassio, A., Pagotto, U., & Balsamo, A. (2018) · Sexual Development · doi:10.1159/000486840 · Cited by 31

Revisiting hyper- and hypo-androgenism by tandem mass spectrometry

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Progressive Improvement ofT-Scores in Men with Osteoporosis and Subnormal Serum Testosterone Levels upon Treatment with Testosterone over Six Years

Haider, A., Meergans, U., Traish, A. M., Saad, F., Doros, G. D., Lips, P. T. A. M., & Gooren, L. J. (2014) · International Journal of Endocrinology · doi:10.1155/2014/496948 · Cited by 32

Muscles of the trunk and pelvis are responsive to testosterone administration: data from testosterone dose–response study in young healthy men

Tapper, J., Arver, S., Pencina, K. M., Martling, A., Blomqvist, L., Buchli, C., Li, Z., Gagliano‐Jucá, T., Travison, T. G., Huang, G. T.-W., et al. (2017) · Andrology · doi:10.1111/andr.12454 · Cited by 29

EMAS position statement: Testosterone replacement therapy in older men

Kanakis, G., Pofi, R., Goulis, D. G., Isidori, A. M., Armeni, E., Erel, C. T., Fistonić, I., Hillard, T., Hirschberg, A. L., Męczekalski, B., et al. (2023) · Maturitas · doi:10.1016/j.maturitas.2023.107854 · Cited by 35

Draft of Russian Clinical Practice Guidelines «Male hypogonadism»

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Testosterone and cardiometabolic risk in the general population – the impact of measurement method on risk associations: a comparative study between immunoassay and mass spectrometry

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Reference Ranges and Association of Age and Lifestyle Characteristics with Testosterone, Sex Hormone Binding Globulin, and Luteinizing Hormone among 1166 Western Chinese Men

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Could Testosterone Replacement Therapy in Hypogonadal Men Ameliorate Anemia, a Cardiovascular Risk Factor? An Observational, 54-Week Cumulative Registry Study

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Waist circumference is superior to weight and BMI in predicting sexual symptoms, voiding symptoms and psychosomatic symptoms in men with hypogonadism and erectile dysfunction

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Health Outcomes Among Long-term Opioid Users With Testosterone Prescription in the Veterans Health Administration

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Prostate-Specific Antigen Levels During Testosterone Treatment of Hypogonadal Older Men: Data from a Controlled Trial

Cunningham, G. R., Ellenberg, S. S., Bhasin, S., Matsumoto, A. M., Parsons, J. K., Preston, P. E., Cauley, J. A., Gill, T. M., Swerdloff, R. S., Wang, C., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-00806 · Cited by 28

Clinical use of testosterone in hypogonadism and other conditions

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Could androgens be relevant to partly explain why men have lower life expectancy than women?

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Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study

Travison, T. G., O’Donnell, C. J., Bhasin, S., Massaro, J. M., Hoffmann, U., Vasan, R. S., D’Agostino, R. B., & Basaria, S. S. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-4299 · Cited by 27

Testosterone replacement in aging men: an evidence-based patient-centric perspective

Bhasin, S. (2021) · Journal of Clinical Investigation · doi:10.1172/jci146607 · Cited by 27

Testosterone Dose-Response Relationships With Cardiovascular Risk Markers in Androgen-Deficient Women: A Randomized, Placebo-Controlled Trial

Huang, G. T.-W., Tang, E., Aakil, A., Anderson, S. W., Jara, H. J., Davda, M. N., Stroh, H., Travison, T. G., Bhasin, S., & Basaria, S. S. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4160 · Cited by 27

Effects of Testosterone Replacement on Electrocardiographic Parameters in Men: Findings from Two Randomized Trials

Gagliano‐Jucá, T., İçli, T. B., Pencina, K. M., Li, Z., Tapper, J., Huang, G. T.-W., Travison, T. G., Tsitouras, P. D., Harman, S. M., Storer, T. W., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3669 · Cited by 26

Testosterone Deficiency, Long-Term Testosterone Therapy, and Inflammation

Zhang, X., Zhao, H., Horney, J. A., Johnson, N. M., Saad, F., Haider, K. S., Haider, A., & Xu, X. (2021) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/10742484211032402 · Cited by 26

Clinical factors impacting microdissection testicular sperm extraction success in hypogonadal men with nonobstructive azoospermia

Esteves, S. C., Achermann, A. P. P., Miyaoka, R., Verza, S., Jr., Fregonesi, A., & Riccetto, C. (2024) · Fertility and Sterility · doi:10.1016/j.fertnstert.2024.06.013 · Cited by 26

Testosterone and Mood in Aging Men

Seidman, S. N., & Weiser, M. (2013) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2013.01.007 · Cited by 27

Laboratory testing for secondary osteoporosis evaluation

Adler, R. A. (2012) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2012.01.024 · Cited by 26

Clomiphene Citrate Effectively Increases Testosterone in Obese, Young, Hypogonadal Men

Bendre, S. V., & Murray, P. J. (2015) · Reproductive System & Sexual Disorders · doi:10.4172/2161-038x.1000155 · Cited by 26

Effect of testosterone treatment on bone remodelling markers and mineral density in obese dieting men in a randomized clinical trial

Fui, M. N. T., Hoermann, R., Nolan, B. J., Clarke, M., Zajac, J. D., & Grossmann, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-27481-3 · Cited by 26

Effects of testosterone replacement on metabolic and inflammatory markers in men with opioid-induced androgen deficiency

Huang, G., Travison, T., Maggio, M., Edwards, R. R., & Basaria, S. (2016) · Clinical Endocrinology · doi:10.1111/cen.13049 · Cited by 26

The effects of testosterone administration on muscle areas of the trunk and pelvic floor in hysterectomized women with low testosterone levels: proof-of-concept study

Tapper, J., Huang, G. T.-W., Pencina, K. M., Li, Z., Arver, S., Martling, A., Blomqvist, L., Buchli, C., Travison, T. G., Storer, T. W., et al. (2019) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001410 · Cited by 25

Reference intervals for free testosterone in adult men measured using a standardized equilibrium dialysis procedure

Jasuja, R., Pencina, K. M., Spencer, D. J., Peng, L., Privat, F., Dhillo, W. S., Jayasena, C. N., Hayes, F. J., Yeap, B. B., Matsumoto, A. M., et al. (2022) · Andrology · doi:10.1111/andr.13310 · Cited by 25

Approach to the Patient: The Evaluation and Management of Men ≥50 Years With Low Serum Testosterone Concentration

Grossmann, M., Jayasena, C. N., & Anawalt, B. D. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad180 · Cited by 25

Dehydroepiandrosterone sulfate, free testosterone, and sex hormone-binding globulin on susceptibility to attention-deficit/hyperactivity disorder.

Wang, L.-J., Lee, S.-Y., Chou, M., Lee, M.-J., & Chou, W.-J. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.01.025 · Cited by 24

Metformin, testosterone, or both in men with obesity and low testosterone: A double-blind, parallel-group, randomized controlled trial

Fernández‐García, J. C., Barrios‐Rodríguez, R., Asenjo‐Plaza, M., Ramos‐Molina, B., Molina‐Vega, M., Guzmán-Guzmán, A., Moreno-León, L., Yubero‐Serrano, E. M., Ríus, F., Valdés, S., et al. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155290 · Cited by 27

Osteocalcin increase after bariatric surgery predicts androgen recovery in hypogonadal obese males

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Andropause or Male Menopause? Rationale for Testosterone Replacement Therapy in Older Men with Low Testosterone Levels

Cunningham, G. R. (2013) · Endocrine Practice · doi:10.4158/ep13217.ra · Cited by 24

Relationship Between Sex Steroids and Deterioration of Bone Microarchitecture in Older Men: The Prospective STRAMBO Study

Piot, A., Chapurlat, R. D., Claustrat, B., & Szulc, P. (2019) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3746 · Cited by 26

Reviewing the Evidence on Vitamin D Supplementation in the Management of Testosterone Status and Its Effects on Male Reproductive System (Testis and Prostate): Mechanistically Dazzling but Clinically Disappointing

Santos, H. O., Howell, S. L., Nichols, K., & Teixeira, F. J. (2020) · Clinical Therapeutics · doi:10.1016/j.clinthera.2020.03.016 · Cited by 24

Association of Male Hypogonadism With Risk of Hospitalization for COVID-19

Dhindsa, S., Champion, C. D., Deol, E. S., Lui, M., Campbell, R. G., Newman, J., Yeggalam, A., Nadella, S., Ahir, V., Shrestha, E., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.29747 · Cited by 24

Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work

Kelly, M. R., Yuen, F., Satterfield, B. C., Auchus, R. J., Gaddameedhi, S., Dongen, H. P. A. V., & Liu, P. Y. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac153 · Cited by 23

Scientific overview of hormone treatment used for rejuvenation

Morley, J. E. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.04.009 · Cited by 23

Clinical practice patterns in the assessment and management of low testosterone in men: an international survey of endocrinologists

Grossmann, M., Anawalt, B. D., & Wu, F. C. W. (2014) · Clinical Endocrinology · doi:10.1111/cen.12594 · Cited by 23

Dose-Response Relationships Between Gonadal Steroids and Bone, Body Composition, and Sexual Function in Aging Men

Finkelstein, J. S., Lee, H., Burnett‐Bowie, S. M., Darakananda, K., Gentile, E. C., Goldstein, D. W., Prizand, S. H., Krivicich, L. M., Taylor, A. P., Wulczyn, K. E., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa318 · Cited by 23

Immunity and the Endocrine System

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Serum cortisol as a moderator of the relationship between serum testosterone and Olympic weightlifting performance in real and simulated competitions

Crewther, B. T., Obmiński, Z., & Cook, C. J. (2018) · Biology of Sport · doi:10.5114/biolsport.2018.74632 · Cited by 22

Sex steroids and sex steroid‐binding globulin levels amongst middle‐aged and elderly men and women from general population

Aribas, E., van Lennep, J. E. R., de Rijke, Y. B., Laven, J. S. E., Ikram, M. A., Peeters, R. P., & Kavousi, M. (2022) · European Journal of Clinical Investigation · doi:10.1111/eci.13866 · Cited by 22

Relationship Between Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms and Total Serum Testosterone Level in Healthy Middle-Aged Eugonadal Men

Lee, J. H., Kim, Y., Park, Y. W., & Lee, D. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12489 · Cited by 22

Oxidative Stress, Nutritional Antioxidants, and Testosterone Secretion in Men

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