Labrie, Fernand

Identification of late-onset hypogonadism in middle-aged and elderly men

Wu, F. C. W., Tajar, A., Beynon, J. M., Pye, S. R., Silman, A. J., Finn, J. D., O'Neill, T. W., Bartfai, G., Casanueva, F. F., Forti, G., et al. (2010) · New England Journal of Medicine

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 1,544

Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging

Labrie, F., Bélanger, A., Cusan, L., Gomez, J.-L., & Candas, B. (1997) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 713

Intracrinology

Labrie, F. (1991) · Molecular and Cellular Endocrinology

Estrogen and related hormone effectsProstate Cancer Treatment and Research

Cited by 685

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evidence from the European Male Ageing Study

Tajar, A., Forti, G., O'Neill, T. W., Lee, D. M., Silman, A. J., Finn, J. D., Bartfai, G., Boonen, S., Casanueva, F. F., Giwercman, A., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 604

Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone

Labrie, F., Luu-The, V., Labrie, C., Bélanger, A., Simard, J., Lin, S.-X., & Pelletier, G. (2003) · Endocrine Reviews

Estrogen and related hormone effectsHormonal and reproductive studies

Cited by 544

The key role of 17β-hydroxysteroid dehydrogenases in sex steroid biology

Labrie, F., Luu-The, V., Lin, S.-X., Claude, L., Simard, J., Breton, R., & Bélanger, A. (1997) · Steroids

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 480

Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ 5 -Δ 4 -lsomerase in Human Adrenals and Gonads

Rhéaume, E., Lachance, Y., Zhao, H.-F., Breton, N., Dumont, M., Launoit, Y. D., Trudel, C., Luu-The, V., Simard, J., & Labrie, F. (1991) · Molecular Endocrinology

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 362

Reference Ranges for Testosterone in Men Generated Using Liquid Chromatography Tandem Mass Spectrometry in a Community-Based Sample of Healthy Nonobese Young Men in the Framingham Heart Study and Applied to Three Geographically Distinct Cohorts

Bhasin, S., Pencina, M., Jasuja, G. K., Travison, T. G., Coviello, A., Orwoll, E., Wang, P. Y., Nielson, C., Wu, F., Tajar, A., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesClinical Laboratory Practices and Quality Control

Cited by 355

Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.

Labrie, F., Bélanger, A., Cusan, L., & Candas, B. (1997) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 350

DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging

Labrie, F., Bélanger, A., Luu-The, V., Labrie, C., Simard, J., Cusan, L., Gomez, J.-L., & Candas, B. (1998) · Steroids

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 347

The dense LDL phenotype. Association with plasma lipoprotein levels, visceral obesity, and hyperinsulinemia in men

Tchernof, A., Lamarche, B., Prud'homme, D., Nadeau, A., Moorjani, S., Labrie, F., Lupien, P. J., & Després, J.-P. (1996) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsLipoproteins and Cardiovascular Health

Cited by 323

Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS)

Tajar, A., Huhtaniemi, I. T., O'Neill, T. W., Finn, J. D., Pye, S. R., Lee, D. M., Bartfai, G., Boonen, S., Casanueva, F. F. F., Forti, G., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesMenopause: Health Impacts and Treatments

Cited by 318

Intracrinology: Role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease

Labrie, F., Luu-The, V, Lin, S., Simard, J., Labrie, C., El-Alfy, M., Pelletier, G., & Belanger, A. (2000) · Journal of Molecular Endocrinology

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 278

Comparison of Crystal Structures of Human Androgen Receptor Ligand-Binding Domain Complexed with Various Agonists Reveals Molecular Determinants Responsible for Binding Affinity

Pereira de Jésus‐Tran, K., Côté, P., Cantin, L., Blanchet, J., Labrie, F., & Breton, R. (2006) · Protein Science

Receptor Mechanisms and SignalingEstrogen and related hormone effects

Cited by 278

Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues.

Simard, J., Luthy, I., Guay, J., Bélanger, A., & Labrie, F. (1986) · Molecular and Cellular Endocrinology

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

Cited by 256

Low Serum Testosterone and Estradiol Predict Mortality in Elderly Men

Tivesten, A., Vandenput, L., Labrie, F., Karlsson, M. K., Ljunggren, O., Mellström, D., & Ohlsson, C. (2009) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesMenopause: Health Impacts and Treatments

Cited by 243

Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans

Bélanger, A., Pelletier, G., Labrie, F., Barbier, O., & Chouinard, S. (2003) · Trends in Endocrinology & Metabolism

Pharmacogenetics and Drug MetabolismProstate Cancer Treatment and Research

Cited by 235

Congenital adrenal hyperplasia due to point mutations in the type II 3β-hydroxysteroid dehydrogenase gene

Rhéaume, E., Simard, J., Morel, Y., Mebarki, F., Zachmann, M., Forest, M. G., New, M. I., & Labrie, F. (1992) · Nature Genetics

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 235

Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues.

Martel, C., Rhéaume, E., Takahashi, M., Trudel, C., Couët, J., Luu-The, V., Simard, J., & Labrie, F. (1992) · The Journal of Steroid Biochemistry and Molecular Biology

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 231

All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause

Labrie, F. (2015) · The Journal of Steroid Biochemistry and Molecular Biology

Estrogen and related hormone effectsMenopause: Health Impacts and Treatments

Cited by 227

Characteristics of human types 1,2 and 3 17β-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition

Luu-The, V., Zhang, Y., Poirier, D., & Labrie, F. (1995) · The Journal of Steroid Biochemistry and Molecular Biology

Steroid Chemistry and BiochemistryEstrogen and related hormone effects

Cited by 224

Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men.

Bélanger, B., Bélanger, A., Labrie, F., Dupont, A., Cusan, L., & Monfette, G. (1989) · Journal of Steroid Biochemistry

Hormonal and reproductive studiesProstate Cancer Treatment and Research

Cited by 212

Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium

Lépine, J., Bernard, O., Plante, M., Têtu, B., Pelletier, G., Labrie, F., Bélanger, A., & Guillemette, C. (2004) · The Journal of Clinical Endocrinology & Metabolism

Pharmacogenetics and Drug MetabolismEstrogen and related hormone effects

Cited by 205

Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells

Lachance, Y., Luu-The, V, Labrie, C., Simard, J., Dumont, M., de Launoit, Y., Guérin, S., Leblanc, G., & Labrie, F. (1990) · Journal of Biological Chemistry

Adrenal Hormones and DisordersSteroid Chemistry and Biochemistry

Cited by 201