Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

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2. Role of irisin in Chinese patients with hypothyroidism: an interventional study
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3. What Is the Relationship Between Body Mass Index, Sex Hormones, Leptin, and Irisin in Children and Adolescents? A Path Analysis
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4. Pentamethylquercetin Regulates Lipid Metabolism by Modulating Skeletal Muscle-Adipose Tissue Crosstalk in Obese Mice
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5. Dietary Intervention, When Not Associated With Exercise, Upregulates Irisin/FNDC5 While Reducing Visceral Adiposity Markers in Obese Rats
   Vanessa de Oliveira Furino, João Manoel Alves, Diego Adorna Marine, Marcela Sene‐Fiorese, Carla Nascimento dos Santos Rodrigues, Cristina Arrais-Lima, Stela Márcia Mattiello, Cynthia Aparecida de Castro, Ricardo Carneiro Borra, Marina Campos Rocha et al. · 2021 · Frontiers in Physiology
6. Serum Levels of Visfatin, Omentin and Irisin in Patients with End-Stage Lung Disease Before and After Lung Transplantation
   Marek Ochman, Marcin Maruszewski, Jacek Wojarski, Sławomir Żegleń, Wojtek Karolak, Anita Stanjek-Cichoracka, Piotr Przybyłowski, Marian Zembala, Michał Kukla · 2017 · Annals of Transplantation
7. Plasma Myostatin Increases with Age in Male Youth and Negatively Correlates with Vitamin D in Severe Pediatric Obesity
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8. The effect of 4-week endurance training on serum levels of irisin and betatrophin in streptozotocin- induced diabetic rats
   Hamid Reza Sadeghipour, Golan Yeganeh, Abdossaleh Zar, Mohsen Salesi, Samad Akbarzadeh, Marco Bernardi · 2020 · Archives of Physiology and Biochemistry
9. Irisin: A Possible Marker of Adipose Tissue Dysfunction in Obesity
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10. Irisin Ameliorate Acute Pancreatitis and Acinar Cell Viability through Modulation of the Unfolded Protein Response (UPR) and PPARγ-PGC1α-FNDC5 Pathways
    Avital Horwitz, Ruth Z Birk · 2024 · Biomolecules
11. Serum Irisin, Myostatin, and Myonectin Correlate with Metabolic Health Markers, Liver Disease Progression, and Blood Pressure in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease and Hypertension
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12. Transcriptional Intermediary Factor 1γ–Induced Irisin in Skeletal Muscle Attenuates Renal Fibrosis in Diabetic Nephropathy
    Jin Hyun Kim, Seunghye Lee, Ha Nee Jang, Sehyun Jung, Myeong Hee Jung, Jeong Won Yun, Haejin Jeon, Hyun‐Jung Kim, Se‐Ho Chang, Eun Ju Lee et al. · 2025 · Journal of Cachexia Sarcopenia and Muscle
13. Descriptive Consideration of Serum Irisin Levels Various Factors: Obesity, Type 2 Diabetes Mellitus, Pre-Diabetic Status, Gender, and Athletics
    O Saleh Maysaa J Majeed · 2014 · Journal of Diabetes & Metabolism
14. Thyroid hormones modulate irisin concentrations in patients with recently onset hypothyroidism following total thyroidectomy
    Raffaella Bocale, ANGELA BARINI, Annamaria D’Amore, M. Boscherin, Stefano Necozione, ANGELA BARINI, Giovambattista Desideri, Celestino Pio Lombardi · 2020 · Journal of Endocrinological Investigation
15. The sympathetic/beta-adrenergic pathway mediates irisin regulation of cardiac functions in zebrafish
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16. Current Insights on the Role of Irisin in Endothelial Dysfunction
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17. Predictive value of serum irisin for chronic heart failure in patients with type 2 diabetes mellitus
    Alexander A. Berezin, Ivan M. Fushtey, Sergii V. Pavlov, Alexander Е. Berezin · 2022 · Molecular Biomedicine
18. Associations of Preoperative Irisin Levels of Paired Cerebrospinal Fluid and Plasma with Physical Dysfunction and Muscle Wasting Severity in Residents of Surgery Wards
    Qingwei Ruan, Yuyuan Huang, Liqin Yang, J. Li, W. Gu, Zhijun Bao, X. Zhang, Zhuowei Yu · 2020 · The journal of nutrition health & aging
19. Research and prospect of peptides for use in obesity treatment (Review)
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20. Irisin/FNDC5: A participant in camel metabolism
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21. Serum irisin level in rheumatoid arthritis patients: Relationship to disease activity, subclinical atherosclerosis, and cardiovascular risk factors
    Samar Soliman, Reem Gad, Tarek Senosy, Aliaa Higazi, Rawhya R. El-Shereef · 2021 · The Egyptian Rheumatologist
22. Interleukin-6 mediates lipopolysaccharide-inhibited irisin secretion in Nile tilapia (Oreochromis niloticus)
    Yisha Yan, Rui Dong, Chaoyi Zhang, Quan Jiang · 2021 · Fish & Shellfish Immunology
23. Serum irisin levels in metabolically healthy versus metabolically unhealthy obesity: A case-control study
    Somaye Yosaee, Reyhane Basirat, Abdolhamid Hamidi, Alireza Esteghamati, Mahmoud Khodadost, Farzad Shidfar, Vida Bitarafan, Kurosh Djafarian · 2020 · Medical Journal of the Islamic Republic of Iran
24. Maternal circulating levels of irisin in intrahepatic cholestasis of pregnancy
    Ayşe Kırbaş, Korkut Dağlar, Hakan Tımur, Ebru Hacer Biberoglu, Hasan Ali İnal, Özgür Kara, Zehra Yilmaz, Gülenay Gençosmanoğlu Türkmen, Nuri Danışman · 2015 · The Journal of Maternal-Fetal & Neonatal Medicine
25. Maternal serum irisin levels in early and late-onset pre-eclamptic and healthy pregnancies
    Ayşegül Özel, Ebru Alıcı Davutoğlu, Asuman Akkaya Fırat, Hakan Erenel, Mehmet Fatih Karslı, Sevim Özge Korkmaz, Rıza Madazlı · 2018 · Journal of Obstetrics and Gynaecology
26. Fasting Insulin and Alanine Amino Transferase, but not FGF21, Were Independent Parameters Related with Irisin Increment after Intensive Aerobic Exercising
    Viridiana Abigahy de la Torre-Saldaña, Miguel Ángel Gómez-Sámano, Francisco Javier Gomez-Perez, Juan Rosas-Saucedo, Andrés León‐Suárez, Mariana Grajales-Gómez, Jorge Oseguera-Moguel, Arturo Vega‐Beyhart, Daniel Cuevas Ramos · 2019 · Revista de investigaci�n Cl�nica
27. Irisin inhibits CCK-8-induced TNF-α production via integrin αVβ5-NF-κB signaling pathways in Nile tilapia (Oreochromis niloticus)
    Wenjun Deng, Zhikai Cao, Rui Dong, Yisha Yan, Quan Jiang · 2023 · Fish & Shellfish Immunology
28. Effects of a Circuit Training Program on Myokine Levels in Insulin‐Resistant Women: A Randomised Controlled Trial
    Joanna Karolkiewicz, Monika Krzywicka, Monika Szulińska, Katarzyna Musialik, Dominka Musiałowska, Jacek Zieliński, Agnieszka Bilska, Marzena Ratajczak · 2024 · Journal of Diabetes Research
29. Role of irisin in metabolic and cardiovascular disorders and its therapeutic potential
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30. Whole-body repeated hyperthermia increases irisin and brain-derived neurotrophic factor: A randomized controlled trial
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31. A newly identified compound activating UCP1 inhibits obesity and its related metabolic disorders
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32. Irisin levels in LMNA-associated partial lipodystrophies
    Faiza Bensmaine, Kenza Benomar, Stéphanie Espiard, Claire Vahé, Kristell Le Mapihan, Georges Lion, Mohamed Lemdani, Emmanuel Chazard, Olivier Ernst, Corinne Vigouroux et al. · 2018 · Diabetes & Metabolism
33. Chicoric acid does not restore palmitate-induced decrease in irisin levels in PBMCs of newly diagnosed patients with T2D and healthy subjects
    Zahra Arab Sadeghabadi, Roghayeh Abbasalipourkabir, Roohollah Mohseni, Nasrin Ziamajidi · 2019 · Archives of Physiology and Biochemistry
34. Therapeutic role of FNDC5/irisin in attenuating liver fibrosis via inhibiting release of hepatic stellate cell-derived exosomes
    Xin Liao, Yilin Luo, Fang Gu, Wen Song, Xin Nie, Qin Yang · 2023 · Hepatology International
35. Circulating Irisin is Increased in Type 2 Diabetes Mellitus and Correlates with Fasting Glucose Levels
    Kathryna F. Rodrigues, Nathalia Teixeira Pietrani, Adriana Bosco, Cláudia Natália Ferreira, Karina Braga Gomes · 2016 · Apollo Medicine
36. Fibroblast Growth Factor 21, Adiponectin, and Irisin as Markers of Unfavorable Metabolic Features in 12-Year-Old Children
    Satu Seppä, Sirpa Tenhola, Raimo Voutilainen · 2019 · Journal of the Endocrine Society
37. Fibronectin type III domain-containing protein 5 promotes proliferation and differentiation of goat adipose-derived stem cells
    Yanhua Dong, Siyuan Zhang, Jin Tao, Xiaomeng Zhang, Ju Zhang, Jie Yang, Hao Liang, Dongjun Liu, Ming Cang · 2019 · Research in Veterinary Science
38. New insights into the effects of irisin levels in HIV-infected subjects: correlation with adiposity, fat-free mass, and strength parameters
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39. The effect of 60 days of 6° head-down-tilt bed rest on circulating adropin, irisin, retinol binding protein-4 (RBP4) and individual metabolic responses in young, healthy males
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40. FNDC5/Irisin mitigates high glucose-induced neurotoxicity in HT22 cell via ferroptosis
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41. Crosstalk Between Skeletal Muscle and Proximal Connective Tissues in Lipid Dysregulation in Obesity and Type 2 Diabetes
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42. Effects of Quercetin and Coenzyme Q10 on Biochemical, Molecular, and Morphological Parameters of Skeletal Muscle in Trained Diabetic Rats
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43. Change of Fibroblast Growth Factor 21 Level Correlates with the Severity of Diabetic Sensory Polyneuropathy after Six-Week Physical Activity
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44. Significance of Plasma Irisin, Adiponectin, and Retinol Binding Protein-4 Levels as Biomarkers for Obstructive Sleep Apnea Syndrome Severity
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45. Effects of low fat diet on inflammatory parameters in individuals with obesity/overweight and non-alcoholic fatty liver disease: A cross-sectional study
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46. Bioelectrical Impedance Analysis Demonstrates Reliable Agreement with Dual-Energy X-ray Absorptiometry in Identifying Reduced Skeletal Muscle Mass in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Hypertension
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47. Irisin impact as a medication that ameliorate and hinder the development of insulin resistance associated disorders without regular exercise (experimental study)
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48. Identification and characterization of metformin on peptidomic profiling in human visceral adipocytes
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49. Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD
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50. Roles of FGF21 and irisin in obesity-related diabetes and pancreatic diseases
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51. Exists a role for serum irisin in Egyptian Behcet’s patients with subclinical atherosclerosis?
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52. Effects of the Myokine Irisin on Stromal Cells from Swine Adipose Tissue
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53. Association of Plasma Irisin Levels with Circulating Endothelial Microparticles (EMPs) and Endothelial Progenitor Cells (EPCs) in Children Born Prematurely
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54. Effects of High-Intensity Interval Vs. Moderate-Intensity Continuous Training on Body Composition and Gene Expression of ACE2, NLRP3, and FNDC5 in Obese Adults: A Randomized Controlled Trial
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55. The Effect of Bariatric Surgery on Irisin Level: a Systematic Review and Meta-analysis
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56. New Physiological Aspects of Brown Adipose Tissue
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57. Impact of supervised exercise training on pulmonary function parameters, exercise capacity and Irisin Biomarker in Interstitial lung disease patients
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58. Irisin plays an important role in the outcomes of newly diagnosed prediabetes in adults in Guiyang, China
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59. The association between circulating irisin, osteocalcin and FGF21 levels with anthropometric characteristics and blood lipid profile in young obese male subjects
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60. Potential role of integrin αV as irisin receptor and advances in research
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61. Bioconversion-Based Postbiotics Enhance Muscle Strength and Modulate Gut Microbiota in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial
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62. Irisina: ¿transmisor de mensajes del Olimpo?
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63. SERUM IRISIN AND LEPTIN LEVELS IN OBESE AND NON-OBESE WOMEN WITH POLYCYSTIC OVARY SYNDROME WITH REFERENCE TO GLUCOSE HOMEOSTASIS
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64. Correlates and Consequences of High Serum Irisin Concentration in Patients on Hemodialysis: A Longitudinal Analysis
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65. Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin
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66. Irisin Concentrations as a Myocardial Biomarker
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67. The Effect of Pubertal Stage on the Concentrations of the Novel Adipomyokine, Irisin, in Male Adolescents
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68. İrisin ve Vasküler Kontraktilite Üzerine Etkileri
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69. Irisin as a Potential Biomarker Associated with Myocardial Injuries in Patients with Severe Hypothyroidism
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70. Exercise perspective on common cardiac medications
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71. Novel Biomarkers to Understand Cardiovascular Complications in Diabetes
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72. Effects of Hypnotherapy on Weight Loss and thus on Serum Leptin, Adiponectin, and Irisin Levels in Obese Patients
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73. The Effect of Eight Weeks of Circuit Resistance Training and Spirulina Supplementation on Plasma Levels of Irisin and Some Body Composition in Overweight and Obese Men
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74. Comprehensive evaluation of irisin levels in fetomaternal circulation of pregnant women with obesity or gestational diabetes mellitus
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75. Irisin level and neonatal birthweight: A systematic review and meta-analysis
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76. Changes of Circulating Irisin and High-Sensitivity C-Reactive Protein Levels in Morbidly Obese Individuals with Type 2 Diabetes After Roux-en-Y Gastric Bypass
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77. The Impact of Serum and Follicular Fluid Irisin on Oocyte and Embryonic Characteristics in Infertile Women Undergoing ICSI According to BMI
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78. Irisin influences the in vitro differentiation of human mesenchymal stromal cells, promoting a tendency toward beiging adipogenesis
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79. Increased FNDC5/IRISIN protein expression in breast cancer tissue is associated with obesity in postmenopausal women
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80. Irisin: As a Therapeutic Target for Metabolic Disorders
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81. Ablation of Ghrelin Receptor Mitigates the Metabolic Decline of Aging Skeletal Muscle
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82. Serum Irisin Level Increases Throughout the Gestational Period and it Does Not Play a Role in Development of Gestational Diabetes Mellitus
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83. Acute Effects of Aerobic Treadmill Exercise Intensity on Expression of Irisin and FNDC5 in Male Mouse
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85. Irisin in Type 2 Diabetes and Obesity: A Biomarker of Metabolic and Lipid Dysregulation
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87. Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells
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90. Irisin and Metabolic Disorders
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94. Aerobic exercise modulates noncoding RNA network upstream of FNDC5 in the Gastrocnemius muscle of high-fat-diet-induced obese mice
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95. Clinical Importance of FNDC-5 and Selectin-E mRNA Expression Among Type 2 Diabetics with and without Obesity
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100. Irisin Peptide is Myokine, Anti-Obesity and Anti-Lipidemic Factor
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