Cited by 138Hormonal and reproductive studiesSperm and Testicular FunctionAdrenal Hormones and Disorders

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

The Simultaneous Radioimmunoassay of Seven Steroids in Human Spermatic and Peripheral Venous Blood

HAMMOND, G. L., RUOKONEN, A., KONTTURI, M., KOSKELA, E., VIHKO, R.·1977·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jcem-45-1-16

Open this paper in CoChat — free account

Abstract

Seven unconjugated neutral steroids, including testosterone and some of its precursors and metabolites, were measured in the peripheral and spermatic venous blood males, employing specific radioimmunoassays after the fractionation of steroids on Lipidex-5000 (hydroxyalkoxypropyl Sephadex) microcolumns. Respective mean concentrations (ng/ml) and ranges of steroids estimated in peripheral and spermatic venous blood in all groups of patients were as follows: pregnenolone, 0.71 (0.29-2.39) and 10.97 (0.83-30.1); progesterone, 0.31 (0.02-0.57) and 10.17 (1.51-33.24); 17 alpha-hydroxyprogesterone, 1.04 (0.48-2.20) and 37.33 (1.68-141.00); androstenedione, 1.01 (0.26-2.65) and 11.87 (0.97-30.18); testosterone, 3.84 (0.63-10.64) and 255.1 (2.85-619.1); 5alpha-dihydrotestosterone, 0.19 (0.07-0.28) and 3.74 (0.04-9.71); androsterone, 0.27 (0.12-0.47) and 0.97 (0.20-2.15). Concentrations are similar to those estimated by mass spectrometry and protein binding assays, except for androsterone which has not previously been measured in this context. The low, but significant testicular secretion of both 5alpha-hydrotestosterone and androsterone suggests that these two steroids are testicular androgen metabolites, and that androgen metabolism in this tissue may be monitored by way of their measurement in spermatic vein blood.

Integrity signals

Registry

Crossref · 10.1210/jcem-45-1-16

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Removal of Fatty Acids from Serum Albumin by Charcoal Treatment
Chen, R. F. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)81445-x · Cited by 2,093
STEROID-PROTEIN CONJUGATES
Erlanger, B. F., Borek, F., Beiser, S. M., & Lieberman, S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70654-6 · Cited by 790
Androgen transport and receptor mechanisms in testis and epididymis
Hansson, V., Trygstad, O., French, F. S., McLean, W. S., Smith, A. A., Tindall, D. J., WEDDINGTON, S. C., Petrusz, P., Nayfeh, S. N., & Ritzén, E. M. (1974) · Nature · doi:10.1038/250387a0 · Cited by 239
Secretion of unconjugated androgens and estrogens by the normal and abnormal human testis before and after human chorionic gonadotropin
Weinstein, R. L., Kelch, R. P., Jenner, M. R., Kaplan, S. L., & Grumbach, M. M. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107526 · Cited by 170
Measurement of Testosterone and 17-Ketosteroids in Plasma by the Double Isotope Dilution Derivative Technique1
GANDY, H. M., & Peterson, R. E. (1968) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-28-7-949 · Cited by 168
The Role of Androgens in the Initiation of Spermatogenesis in Man
Steinberger, E., Root, A. W., Ficher, M., & Smith, K. D. (1973) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-37-5-746 · Cited by 137
Simultaneous determination of five sex hormones in human serum by radioimmunoassay after chromatography on Lipidex-5000.
Apter, D. L., Jänne, O. A., Karvonen, P., & Vihko, R. (1976) · Clinical Chemistry · doi:10.1093/clinchem/22.1.32 · Cited by 125
Self-citation
Free and sulfate-conjugated neutral steroids in human testis tissue
Ruokonen, A., Laatikainen, T. K., LAITINEN, E. A., & Vihko, R. (1972) · Biochemistry · doi:10.1021/bi00758a013 · Cited by 115
Self-citation
PLASMA STEROID AND PROTEIN HORMONE CONCENTRATIONS IN PATIENTS WITH PROSTATIC CARCINOMA, BEFORE AND DURING OESTROGEN THERAPY
Harper, M. E., Peeling, W. B., Cowley, T., Brownsey, B. G., Phillips, M. E., Groom, G. V., Fahmy, D. R., & Griffiths, K. (1976) · European Journal of Endocrinology · doi:10.1530/acta.0.0810409 · Cited by 109
Influence of Major Surgical Stress on Plasma Levels of Testosterone, Luteinizing Hormone and Follicle-Stimulating Hormone in Male Patients
Aono, T., Kurachi, K., Mizutani, S., HAMANAKA, Y., UOZUMI, T., Nakasima, A., KOSHIYAMA, K., & Matsumoto, K. (1972) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-35-4-535 · Cited by 100

Show all 23 references

Sorted by citations

Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma
DUNN, J. F., NISULA, B. C., & RODBARD, D. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-53-1-58 · Cited by 1,238
The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications
Kaufman, J. M., & Vermeulen, A. (2005) · Endocrine Reviews · doi:10.1210/er.2004-0013 · Cited by 1,079
The regulation of spermatogenesis by androgens
Smith, L. B., & Walker, W. H. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.02.012 · Cited by 849
Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review
Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105439 · Cited by 450
The Roles of Luteinizing Hormone, Follicle-Stimulating Hormone and Testosterone in Spermatogenesis and Folliculogenesis Revisited
Oduwole, O. O., Huhtaniemi, I. T., & Misrahi, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312735 · Cited by 340
Profiling steroid hormones and urinary steroids
Shackleton, C. H. L. (1986) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/s0378-4347(00)80683-0 · Cited by 291
Non-classical actions of testosterone and spermatogenesis
Walker, W. H. (2010) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0258 · Cited by 284
Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation
Flück, C. E., Meyer-Böni, M., Pandey, A. V., Kempná, P., Miller, W. L., Schoenle, E. J., & Biason-Lauber, A. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.06.009 · Cited by 248
Intracrine androgen biosynthesis, metabolism and action revisited
Schiffer, L., Arlt, W., & Storbeck, K.-H. (2018) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.08.016 · Cited by 217
“Concentrations of androgen in testicular venous blood of healthy individuals are T (high nanomolar-low micromolar) » A4, DHEA (medium nanomolar) (Hammond et al., 1977; Ishida et al., 1990; Weinstein et al., 1974).”
Molecular mechanisms of testosterone action in spermatogenesis☆
Walker, W. H. (2008) · Steroids · doi:10.1016/j.steroids.2008.11.017 · Cited by 196
SERUM STEROIDS AND PITUITARY HORMONES IN FEMALE PUBERTY: A PARTLY LONGITUDINAL STUDY
Apter, D. L. (1980) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1980.tb02125.x · Cited by 182
Sex steroids and 5-en-3β-hydroxysteroids in specific regions of the human brain and cranial nerves
Lanthier, A., & Patwardhan, V. V. (1986) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(86)90259-1 · Cited by 182
Hormonal Pattern of Adolescent Menstrual Cycles*
Apter, D. L., Viinikka, L. U., & Vihko, R. (1978) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-47-5-944 · Cited by 171
Self-citation
Rat Testicular Endogenous Steroids and Number of Leydig Cells Between the Fetal Period and Sexual Maturity
Tapanainen, J. S., Kuopio, T., Pelliniemi, L. J., & Huhtaniemi, I. T. (1984) · Biology of Reproduction · doi:10.1095/biolreprod31.5.1027 · Cited by 150
Age-Related Changes in Endogenous Steroids of Human Fetal Testis during Early and Midpregnancy*
Tapanainen, J. S., Kellokumpu‐Lehtinen, P., Pelliniemi, L. J., & Huhtaniemi, I. T. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-52-1-98 · Cited by 147
The Influence of Sex Hormones in Liver Function and Disease
Kasarinaite, A., Sinton, M. C., Saunders, P. T. K., & Hay, D. C. (2023) · Cells · doi:10.3390/cells12121604 · Cited by 139
Endogenous Steroids in the Rat Seminiferous Tubules. Comparison of the Stages of the Epithelial Cycle Isolated by Transillumination‐Assisted Microdissection
Parvinen, M., & Ruokonen, A. (1982) · Journal of Andrology · doi:10.1002/j.1939-4640.1982.tb00672.x · Cited by 116
Self-citation
Backdoor pathway for dihydrotestosterone biosynthesis: implications for normal and abnormal human sex development
Fukami, M., Homma, K., Hasegawa, T., & Ogata, T. (2013) · Developmental Dynamics · doi:10.1002/dvdy.23892 · Cited by 114
Anticonvulsant Activity of Androsterone and Etiocholanolone
Kaminski, R. M., Marini, H. R., Kim, W., & Rogawski, M. A. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.00705.x · Cited by 108
Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling1
Toocheck, C., Clister, T., Shupe, J. A., Crum, C. M., Ravindranathan, P., Lee, T.-K., Ahn, J., Raj, G. V., Sukhwani, M., Orwig, K. E., et al. (2015) · Biology of Reproduction · doi:10.1095/biolreprod.115.132068 · Cited by 108
WHICH TESTOSTERONE REPLACEMENT THERAPY?
Cantrill, J. A., Dewis, P., Large, D. M., Newman, M., & Anderson, D. C. (1984) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1984.tb03448.x · Cited by 102
SERUM STEROIDS IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES
Hammond, G. L., Kontturi, M. J., Vihko, P., & Vihko, R. (1978) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1978.tb02189.x · Cited by 87
Self-citation
Enhanced Activity of the Pituitary-Gonadal Axis in Premature Human Infants*
Tapanainen, J. S., KOIVISTO, M., Vihko, R., & Huhtaniemi, I. T. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-52-2-235 · Cited by 85
Self-citation
Testosterone and estradiol are co-secreted episodically by the human testis.
Winters, S. J., & Troen, P. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112673 · Cited by 83
Metoclopramide-Induced Hyperprolactinemia Impairs Ovarian Follicle Maturation and Corpus Luteum Function in Women*
Kauppila, A., Leinonen, P., Vihko, R., & Ylöstalo, P. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-5-955 · Cited by 82
Self-citation
lnterferon-γ Inhibits Steroidogenesis and Accumulation of mRNA of the Steroidogenic Enzymes P450scc and P450c17 in Cultured Porcine Leydig Cells
Orava, M., Voutilainen, R., & Vihko, R. (1989) · Molecular Endocrinology · doi:10.1210/mend-3-6-887 · Cited by 77
Self-citation
Reproductive Aging in Men
Basaria, S. S. (2013) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2013.02.012 · Cited by 75
Plasma 5α-Reduced Androgens in Men and Hirsute Women: Role of Adrenals and Gonads*
Meikle, A. W., Stringham, J. D., Wilson, D. E., & Dolman, L. I. (1979) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-48-6-969 · Cited by 71
CIRCULATING SEX HORMONE‐BINDING GLOBULIN AND TESTOSTERONE IN NEWBORNS AND INFANTS
BOLTON, N. J., TAPANAINEN, J., KOIVISTO, M., & VIHKO, R. (1989) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1989.tb01243.x · Cited by 78
Self-citation
Testosterone: An overview of biosynthesis, transport, metabolism and nongenomic actions
ROMMERTS, F. F. G. (1998) · Springer eBooks · doi:10.1007/978-3-642-72185-4_1 · Cited by 68
Follow up of growth and steroids in premature adrenarche
PERE, A.-K., Perheentupa, J., Peter, M., & Voutilainen, R. (1995) · European Journal of Pediatrics · doi:10.1007/bf02072100 · Cited by 67
Newer Approaches to the Isolation, Identification, and Quantitation of Steroids in Biological Materials
Sjövall, J., & Axelson, M. (1982) · Vitamins and hormones · doi:10.1016/s0083-6729(08)61135-8 · Cited by 63
Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man
Ruokonen, A., Alén, M., Bolton, N. J., & Vihko, R. (1985) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(85)90257-2 · Cited by 62
Self-citation
Low Expression of 3β-Hydroxy-5-Ene Steroid Dehydrogenase Gene in Human Fetal Adrenals in Vivo; Adrenocorticotropin and Protein Kinase C-Dependent Regulation in Adrenocortical Cultures
VOUTILAINEN, R., ILVESMÄKI, V., & MIETTINEN, P. J. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-4-761 · Cited by 61
Photoperiod-Induced Changes in Androgen Receptor Expression in Testes and Accessory Sex Glands of the Bank Vole, Clethrionomys glareolus 1
Tähkä, K. M., Zhuang, Y.-H., Tähkä, S., & Tuohimaa, P. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.4.898 · Cited by 53
RESPONSE OF PERIPHERAL SERUM SEX STEROIDS AND SOME OF THEIR PRECURSORS TO A SINGLE INJECTION OF hCG IN ADULT MEN
Martikainen, H. K., Huhtaniemi, I. T., & Vihko, R. (1980) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1980.tb01037.x · Cited by 53
Self-citation
Testicular secretion of conjugated and unconjugated steroids in normal adults and in patients with varicocele
Scholler, R., NAHOUL, K., Castanier, M., Rotman, J., & Salat‐Baroux, J. (1984) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(84)90207-3 · Cited by 52
Testicular responsiveness to human chorionic gonadotrophin during transient hypogonadotrophic hypogonadism induced by androgenic/anabolic steroids in power athletes
Martikainen, H. K., Alén, M., Rahkila, P., & Vihko, R. (1986) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(86)90288-8 · Cited by 47
Self-citation
Growth retardation in children receiving long-term total parenteral nutrition: effects of ornithine α-ketoglutarate
Moukarzel, A. A., Goulet, O., Salas, J., Martí-Henneberg, C., BUCHMAN, A. P., Cynober, L., Rappaport, R., & Ricour, C. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.3.408 · Cited by 47
Melatonin excretion in normal males and females: Increase during puberty
Penny, R. (1982) · Metabolism · doi:10.1016/0026-0495(82)90081-6 · Cited by 47
Circulating steroid hormone variations throughout different stages of prostate cancer
Snaterse, G., Visser, J. A., Arlt, W., & Hofland, J. (2017) · Endocrine Related Cancer · doi:10.1530/erc-17-0155 · Cited by 44
Hormone Signaling in the Testis
Smith, L. B., & Walker, W. H. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00016-8 · Cited by 46
STEROIDOGENIC RESPONSE TO A SINGLE INJECTION OF hCG IN PRE‐ AND EARLY PUBERTAL CRYPTORCHID BOYS
Tapanainen, J. S., Martikainen, H. K., Dunkel, L., Perheentupa, J., & Vihko, R. (1983) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1983.tb00579.x · Cited by 45
Self-citation
Progesterone, androstenedione, testosterone, 5α-dihydrotestosterone and androsterone concentrations in specific regions of the human brain
Hammond, G. L., Hirvonen, J., & Vihko, R. (1983) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(83)90086-9 · Cited by 44
Self-citation
Zinc and cadmium concentrations in whole tissue and in separated epithelium and stroma from human benign prostatic hypertrophic glands
Lahtonen, R. (1985) · The Prostate · doi:10.1002/pros.2990060208 · Cited by 44
Puberty and its Disorders in Boys
Styne, D. M. (1991) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30281-0 · Cited by 44
The Radioimmunoassay of Testosterone, 5α‐Dihydrotestosterone and Their Precursors in the Human Testis
Hammond, G. L., Ahonen, V., & Vihko, R. (1978) · International Journal of Andrology · doi:10.1111/j.1365-2605.1978.tb00031.x · Cited by 43
Self-citation
Letter to the editor
Orava, M., Cantell, K., & Vihko, R. (1986) · International Journal of Cancer · doi:10.1002/ijc.2910380222 · Cited by 42
Self-citation
GnRH and HCG Tests Are Both Necessary in Differential Diagnosis of Male Delayed Puberty
Dunkel, L. (1985) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1985.02140070068036 · Cited by 41
Effect of Orchidectomy on Serum Concentrations of Testosterone and Dihydrotestosterone in Patients with Prostatic Cancer
Røhl, H., & Beuke, H.-P. (1992) · Scandinavian Journal of Urology and Nephrology · doi:10.3109/00365599209180389 · Cited by 38
Testosterone and the Androgen Receptor
Gerald, T., & Raj, G. V. (2022) · Urologic Clinics of North America · doi:10.1016/j.ucl.2022.07.004 · Cited by 38
Hormonal changes during the perinatal period: Serum testosterone, some of its precursors, and FSH and prolactin in preterm and fullterm male infant cord blood and during the first week of life
Tapanainen, J. S. (1983) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(83)90323-0 · Cited by 33
Biochemical and Physiological Aspects of Endogenous Androgens
Kicman, A. T. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-79088-4_2 · Cited by 33
Composition of fluids obtained from human epididymal cysts
Cooper, T. G., Raczek, S., Yeung, C., Schwab, E., Schulze, H., & Hertle, L. (1992) · Urological Research · doi:10.1007/bf00300258 · Cited by 31
The role of androgens in adolescent cycles
Vihko, R., & Apter, D. L. (1980) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(80)90295-2 · Cited by 31
Self-citation
Comparison of serum steroid responses to a single injection of hCG in man and rat
Huhtaniemi, I. T., Bolton, N. J., Martikainen, H. K., & Vihko, R. (1983) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(83)90409-0 · Cited by 30
Self-citation
EFFECT OF OESTROGEN TREATMENT ON TESTICULAR LH/hCG RECEPTORS AND ENDOGENOUS STEROIDS IN PROSTATIC CANCER PATIENTS
Huhtaniemi, I. T., Leinonen, P., Hammond, G. L., & Vihko, R. (1980) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1980.tb03424.x · Cited by 30
Self-citation
Testosterone: an overview of biosynthesis, transport, metabolism and action
Rommerts, F. F. G. (1990) · Testosterone · doi:10.1007/978-3-662-00814-0_1 · Cited by 28
Potential clinical role of new aromatase inhibitors
Santen, R. J. (1987) · Steroids · doi:10.1016/0039-128x(87)90040-7 · Cited by 28
Effects of Estrogen Treatment on Human Testicular Unconjugated Steroid and Steroid Sulfate Production in Vivo*
Leinonen, P., Ruokonen, A., Kontturi, M. J., & Vihko, R. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-53-3-569 · Cited by 28
Self-citation
A radioimmunoassay for dehydroepiandrosterone sulfate in the circulation of rhesus monkeys
Koritnik, D. R. (1983) · Steroids · doi:10.1016/0039-128x(83)90129-0 · Cited by 25
STEROIDS IN OVARIAN AND PERIPHERAL VENOUS BLOOD IN POLYCYSTIC OVARIAN DISEASE
Laatikainen, T., Apter, D. L., Paavonen, J. A., & Wahlström, T. (1980) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1980.tb01033.x · Cited by 25
Testosterone and Some of Its Precursors and Metabolites in the Human Epididymis*
Leinonen, P., & HAMMON, G. L. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-51-3-423 · Cited by 23
A method for identification and follow-up of patients with a steroid-21-hydroxylase deficiency
Sólyom, J., Hammond, G. L., & Vihko, R. (1979) · Clinica Chimica Acta · doi:10.1016/0009-8981(79)90104-9 · Cited by 23
Self-citation
Temporal Changes in Testicular Histology and Steroidogenesis in Juvenile Bank Voles (Clethrionomys glareolus, Schreber) Subjected to Different Photoperiods*
Tähkä, K. M., Ruokonen, A., WALLGREN, H., & TERÄVÄlNEN, T. (1983) · Endocrinology · doi:10.1210/endo-112-4-1420 · Cited by 23
Self-citation
Antiandrogen withdrawal syndrome (AAWS) in the treatment of patients with prostate cancer
Leone, G., Tucci, M., Buttigliero, C., Zichi, C., Pignataro, D., Bironzo, P., Vignani, F., Scagliotti, G. V., & Maïo, M. D. (2017) · Endocrine Related Cancer · doi:10.1530/erc-17-0355 · Cited by 22
Cortisol and Androgen Secretion in a Case of Nelson's Syndrome with Paratesticular Tumors: Response to Cyproheptadine Therapy*
Krieger, D. T., SAMOJLIK, E., & Bardin, C. W. (1978) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-47-4-837 · Cited by 22
Estrone and estradiol concentrations in the testis and spermatic and peripheral venous blood of elderly men: The influence of estrogen treatment
Leinonen, P. (1980) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(80)90225-3 · Cited by 22
Hormonal changes during the perinatal period: Fsh, prolactin and some steroid hormones in the cord blood and peripheral serum of preterm and fullterm female infants
Tapanainen, J. S., Huhtaniemi, I. T., Koivisto, M. E., Kujansuu, E., Tuimala, R. J., & Vihko, R. (1984) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(84)90359-5 · Cited by 22
Self-citation
Studies on the Relationship Between Sperm Count and Steroid Levels in the Spermatic and Cubital Veins of Patients With Varicocele
de la Torre, B., Norén, S., Hedman, M., & Diczfalusy, E. R. (1978) · International Journal of Andrology · doi:10.1111/j.1365-2605.1978.tb00601.x · Cited by 22
Peripheral and Prostatic Vein Steroid Concentrations in Benign Prostatic Hypertrophy Patients Before and After Removal of the Adenoma
Lukkarinen, O. A., Hammond, G. L., Kontturi, M. J., & Vihko, R. (1980) · Scandinavian Journal of Urology and Nephrology · doi:10.3109/00365598009179566 · Cited by 21
Self-citation
Rapid and slow response of human testicular steroidogenesis to hCG by measurements of steroids in spermatic and peripheral vein blood
Martikainen, H. K., Huhtaniemi, I. T., Lukkarinen, O. A., & Vihko, R. (1982) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(82)90178-9 · Cited by 20
Self-citation
Male Hypogonadism: A Review
Marcelli, M., & Mediwala, S. N. (2020) · Journal of Investigative Medicine · doi:10.1136/jim-2019-001233 · Cited by 23
Androgens and prostate‐specific acid phosphatase in whole tissue and in separated epithelium from human benign prostatic hypertrophic glands
Bolton, N. J., Lahtonen, R., Vihko, P., Kontturi, M. J., & Vihko, R. (1981) · The Prostate · doi:10.1002/pros.2990020408 · Cited by 18
Self-citation
Testicular Disorders
Matsumoto, A. M., & Bremner, W. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00019-8 · Cited by 18
Testicular disorders.
Matsumoto, A. M., & Bremner, W. J. (2011) · Williams Textbook of Endocrinology · doi:10.1016/b978-1-4377-0324-5.00019-5 · Cited by 18
The incidence of second neoplasms following megavoltage radiation for pediatric tumors
Potish, R. A., Dehner, L. P., Haselow, R. E., Kim, T. H., Levitt, S. H., & Nesbit, M. E. (1985) · Cancer · doi:10.1002/1097-0142(19851001)56:7 · Cited by 59
Cytosol estrogen and progesterone receptors in bovine endometrium after uterine involution postpartum and in the estrous cycle
Vesanen, M., ISOMAA, V. V., Alanko, M., & Vihko, R. (1988) · Animal Reproduction Science · doi:10.1016/0378-4320(88)90041-3 · Cited by 18
Self-citation
Development of anti-Müllerian hormone immunoassay based on biolayer interferometry technology
Wang, Y., Dzakah, E. E., Kang, Y., Cai, Y., Wu, P., Cui, Y., Huang, Y., & He, X. (2019) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-019-01928-6 · Cited by 17
It puts the T’s in fertility: testosterone and spermatogenesis
Witherspoon, L., & Flannigan, R. K. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00531-1 · Cited by 17
Pituitary‐Testicular Function of Prostatic Cancer Patients During Treatment with a Gonadotropin‐Releasing Hormone Agonist Analog II. Endocrinology and Histology of the Testis
Huhtaniemi, I., Nikula, H., Parvinen, M., & Rannikko, S. (1987) · Journal of Andrology · doi:10.1002/j.1939-4640.1987.tb00978.x · Cited by 17
Effect of Gonadotropin-Releasing Hormone on Pituitary-Gonadal Function of Male Infants during the First Year of Life*
Tapanainen, J. S., Koivisto, M. E., Huhtaniemi, I. T., & Vihko, R. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-55-4-689 · Cited by 17
Self-citation
Testosterone concentration within the tunica vaginalis of boys and adult men
Karpe, B., Fredricsson, B., Svensson, J., & Ritzén, E. M. (1982) · International Journal of Andrology · doi:10.1111/j.1365-2605.1982.tb00288.x · Cited by 16
MALE PSEUDOHERMAPHRODITISM DUE TO DEFICIENCY OF TESTICULAR 17‐KETOSTEROID REDUCTASE
Leinonen, P., Dunkel, L., Perheentupa, J., & Vihko, R. (1983) · Acta Paediatrica · doi:10.1111/j.1651-2227.1983.tb09699.x · Cited by 16
Self-citation
Concentrations of androgens in human benign prostatic hypertrophic tissues incubated for up to three days
Bolton, N. J., Vihko, R., & Lukkarinen, O. A. (1986) · The Prostate · doi:10.1002/pros.2990090206 · Cited by 16
Self-citation
SERUM PREGNENOLONE, PROGESTERONE, 17α‐HYDROXYPROGESTERONE, ANDROSTENEDIONE, TESTOSTERONE, 5α‐DIHYDROTESTOSTERONE AND ANDROSTERONE DURING PUBERTY IN BOYS
Pakarinen, A., Hammond, G. L., & Vihko, R. (1979) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1979.tb03098.x · Cited by 14
Self-citation
Secretion of Testosterone and Its Δ4Precursor Steroids into Spermatic Vein Blood in Men with Varicocele-Associated Infertility1
Winters, S. J., Takahashi, J. A., & Troen, P. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.3.5548 · Cited by 13
Stimulation of the synthesis of steroids and steroid sulphates in human testicular tissue in vitro by hCG and by 8-bromo-cyclic AMP
Bolton, N. J., Ruokonen, A., & Vihko, R. (1985) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(85)90166-9 · Cited by 13
Self-citation
MEASUREMENT OF SEX HORMONE BINDING GLOBULIN IN HUMAN AMNIOTIC FLUID: ITS RELATIONSHIP TO PROTEIN AND TESTOSTERONE CONCENTRATIONS, AND FETAL SEX
HAMMOND, G. L., LEINONEN, P., BOLTON, N. J., & VIHKO, R. (1983) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1983.tb00582.x · Cited by 17
Self-citation
Total and SHBG‐bound Testosterone and 5α‐Dihydrotestosterone Serum Concentrations in Normal Elderly Men and Patients with Benign Prostatic Hypertrophy Before and After Removal of the Adenoma
Lukkarinen, O. A. (1980) · British Journal of Urology · doi:10.1111/j.1464-410x.1980.tb03063.x · Cited by 12
Comparison of saliva and plasma 17-hydroxyprogesterone time-course response to hCG administration in normal men
NAHOUL, K., & Scholler, R. (1987) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(87)90079-3 · Cited by 12
Bovine Uterine, Cervical and Ovarian Androgen Receptor Concentrations
Vesanen, M., ISOMAA, V. V., Alanko, M., & Vihko, R. (1992) · Acta veterinaria Scandinavica · doi:10.1186/bf03547305 · Cited by 12
Self-citation
hCG‐STIMULATION OF TESTICULAR STEROIDOGENESIS DURING INDUCED HYPER—AND HYPOPROLACTINAEMIA IN MAN
Martikainen, H. K., & Vihko, R. (1982) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1982.tb00711.x · Cited by 12
Self-citation
Effect of clomiphene treatment on the human testicular response to a single dose of hCG
Martikainen, H. K., Leinonen, P., & Vihko, R. (1981) · International Journal of Andrology · doi:10.1111/j.1365-2605.1981.tb00745.x · Cited by 12
Self-citation
Testosterone concentration in different functional compartments of the male reproductive tract
Adamopoulos, D. A., Lawrence, D. M., Vassilopoulos, P., Kontogeorgos, L., Ntounis, A., & Swyer, G. I. M. (1979) · Archives of Andrology · doi:10.3109/01485017908985042 · Cited by 11
Regulation of serum testosterone in men with steroid sulfatase deficiency: Response to human chorionic gonadotropin
Ruoklonen, A., Oikarinen, A., & Vihko, R. (1986) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(86)90289-x · Cited by 11
Self-citation
Endocrinology of testicular neoplasms
Pearson, J. C. (1981) · Urology · doi:10.1016/0090-4295(81)90217-x · Cited by 11
Quantitative Changes of Endogenous Unconjugated and Sulfated Steroids in Human Testis in Relation to Synthesis of Testosterone In Vitro
Ruokonen, A., & Vihko, R. (1983) · Journal of Andrology · doi:10.1002/j.1939-4640.1983.tb00729.x · Cited by 11
Self-citation
Responsiveness of the Pituitary-Testicular Axis to Gonadotropin-releasing Hormone and Chorionic Gonadotropin during the First Week of Life
Dunkel, L., Perheentupa, J., Tapanainen, J. S., Leinonen, P., & Vihko, R. (1984) · Pediatric Research · doi:10.1203/00006450-198411000-00005 · Cited by 10
Self-citation
Rapid endocrine effects of tamoxifen and testolactone in prostatic carcinoma patients
Leinonen, P., Bolton, N. J., Kontturi, M. J., & Vihko, R. (1982) · The Prostate · doi:10.1002/pros.2990030608 · Cited by 10
Self-citation

Authors: HAMMOND, G. L., RUOKONEN, A., KONTTURI, M., KOSKELA, E., & VIHKO, R.
Affiliations: University of Oulu (FI)
ORCID: HAMMOND, G. L.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 1977-07
Volume: 45
Issue: 1
Pages: 16-24
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jcem-45-1-16
OpenAlex: W2162613596
Cited by: 138
References: 23
Citations by year: 2026: 1 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 2 · 2017: 6 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
FWCI: 8.15
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: steroid hormones, peripheral venous blood, testosterone, dihydrotestosterone, androsterone, androstenedione, 17-hydroxyprogesterone, pregnenolone, progesterone
MeSH terms: Adult, Aged, Androstenedione, Androsterone, Hormones, Humans, Male, Middle Aged, Pregnenolone, Progesterone, Prostatic Neoplasms, Radioimmunoassay, Dihydrotestosterone, Steroids, Testis, Testosterone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Simultaneous Radioimmunoassay of Seven Steroids in Human Spermatic and Peripheral Venous Blood

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks