The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Vitamin D: More Than a “Bone-a-Fide” Hormone
Abstract
The vitamin D endocrine system is critical for the proper development and maintenance of mineral ion homeostasis and skeletal integrity. Beyond these classical roles, recent evidence suggests that the bioactive metabolite of vitamin D, 1,25-dihydroxyvitamin D3, functions in diverse physiological processes, such as hair follicle cycling, blood pressure regulation, and mammary gland development. This minireview explores the current progress in unraveling the complexities of the vitamin D endocrine system by focusing on four main areas of research: the resolution of the vitamin D receptor crystal structure, the molecular details of 1,25-dihydroxyvitamin D3-mediated transcription, murine knockout models of key genes in the endocrine system, and alternative vitamin D receptors and ligands.
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Cites
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1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system
Li, Y. C., Kong, J., Wei, M., Chen, Z.-F., Liu, S. Q., & Cao, L.-P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215219 · Cited by 1,625
Vitamin D Receptor As an Intestinal Bile Acid Sensor
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Orphan Nuclear Receptors: The Exotics of Xenobiotics
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Cited by
Inflammation and vitamin D: The infection connection
Mangin, M., Sinha, R., & Fincher, K. (2014) · Inflammation Research · doi:10.1007/s00011-014-0755-z · Cited by 274
Crucial Role of Vitamin D in the Musculoskeletal System
Wintermeyer, E., Ihle, C., Ehnert, S., Stöckle, U., Ochs, G., De Zwart, P., Flesch, I., Bahrs, C., & Nussler, A. (2016) · Nutrients · doi:10.3390/nu8060319 · Cited by 216
The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism
Slominski, A., Semak, I., Zjawiony, J., Wortsman, J., Li, W., Szczesniewski, A., & Tuckey, R. C. (2005) · The FEBS Journal · doi:10.1111/j.1742-4658.2005.04819.x · Cited by 155
Expression of vitamin D receptor decreases during progression of pigmented skin lesions
Brożyna, A. A., Jozwicki, W., Janjetovic, Z., & Slominski, A. T. (2011) · Human Pathology · doi:10.1016/j.humpath.2010.09.014 · Cited by 120
Li, L., Rao, S., Cheng, Y., Zhuo, X., Deng, C., Xu, N., Zhang, H., & Yang, L. (2019) · MicrobiologyOpen · doi:10.1002/mbo3.810 · Cited by 109
“Importantly, it is well known that estrogen directly increases the relative number of Tregs, (Tai et al., 2008) which prevents from ovx‐induced bone loss (Zaiss et al., 2010).”
BackgroundPike, J. W., & Meyer, M. B. (2012) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2012.03.004 · Cited by 86
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Self-citation
Metadata
- Authors
- Sutton, A. L. M., & MacDonald, P. N.
- Venue
- Molecular Endocrinology
- Publisher
- The Endocrine Society
- Published
- 2003-05
- Volume
- 17
- Issue
- 5
- Pages
- 777-791
- ISSN
- 0888-8809 (ISSN-L)
- 1944-9917
- OpenAlex
- W2114764370
- Cited by
- 294
- References
- 6
- FWCI
- 13.72
- Type
- journal article
- Language
- en
- Open access
- closed
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