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Cited by 359

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

The high risk of stroke immediately after transient ischemic attack: A population-based study

Hill, M. D., Yiannakoulias, N., Jeerakathil, T., Tu, J. V., Svenson, L. W., Schopflocher, D. P.·2004·Neurology

Abstract

BACKGROUND: The risk of stroke is elevated in the first 48 hours after TIA. Previous prognostic models suggest that diabetes mellitus, age, and clinical symptomatology predict stroke. The authors evaluated the magnitude of risk of stroke and predictors of stroke after TIA in an entire population over time. METHODS: Administrative data from four different databases were used to define TIA and stroke for the entire province of Alberta for the fiscal year (April 1999-March 2000). The age-adjusted incidence of TIA was estimated using direct standardization to the 1996 Canadian population. The risk of stroke after a diagnosis of TIA in an Alberta emergency room was defined using a Kaplan-Meier survival function. Cox proportional hazards modeling was used to develop adjusted risk estimates. Risk assessment began 24 hours after presentation and therefore the risk of stroke in the first few hours after TIA is not captured by our approach. RESULTS: TIA was reported among 2,285 patients for an emergency room diagnosed, age-adjusted incidence of 68.2 per 100,000 population (95% CI 65.3 to 70.9). The risk of stroke after TIA was 9.5% (95% CI 8.3 to 10.7) at 90 days and 14.5% (95% CI 12.8 to 16.2) at 1 year. The risk of combined stroke, myocardial infarction, or death was 21.8% (95% CI 20.0 to 23.6) at 1 year. Hypertension, diabetes mellitus, and older age predicted stroke at 1 year but not earlier. CONCLUSIONS: Although stroke is common after TIA, the early risk is not predicted by clinical and demographic factors. Validated models to identify which patients require urgent intervention are needed.

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Metadata

Authors
Hill, M. D., Yiannakoulias, N., Jeerakathil, T., Tu, J. V., Svenson, L. W., & Schopflocher, D. P.
Venue
Neurology
Published
2004-06-08
Volume
62
Issue
11
Pages
2015-2020
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2165328975
Cited by
359
References
19
FWCI
17.33
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The high risk of stroke immediately after transient ischemic attack: A population-based study. https://app.cochat.ai/papers/10.1212/01.wnl.0000129482.70315.2f
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Hill, M. D., Yiannakoulias, N., Jeerakathil, T., Tu, J. V., Svenson, L. W., & Schopflocher, D. P. (2004). The high risk of stroke immediately after transient ischemic attack: A population-based study. Neurology. https://doi.org/10.1212/01.wnl.0000129482.70315.2f

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