The DOI matches its Crossref record; 83 of the 84 references it cites were found in a registry or an index.
A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia
Open accessAbstract
OBJECTIVE: To evaluate neurotransmitter deficiencies and neurotransmitter-based treatments for frontotemporal dementia (FTD). METHODS: The authors conducted a systematic review of the literature on the mechanism and treatment of FTD and a meta-analysis of treatment studies of antidepressants for the behavioral symptoms of FTD. RESULTS: Patients with FTD show deficiencies in the serotonin and dopamine neurotransmitter systems, while the acetylcholine system appears relatively intact. Antidepressant treatment significantly improves behavioral symptoms in FTD, but most studies are small and uncontrolled. Serotonergic treatments appear to improve the behavioral but not cognitive symptoms of FTD. CONCLUSIONS: Studies of neurotransmitter deficiencies in frontotemporal dementia (FTD) can be helpful in developing treatments. Treatment studies on FTD are scarce, given the prevalence and severity of this illness. Larger, well-controlled treatment studies are required to reach more definitive conclusions about treatment efficacy. Multicenter studies are likely the best way to complete treatment studies in a timely manner.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“To date, no FTD-specific diagnostic tests or disease-modifying treatments are available and misdiagnosis often leads to an unsuitable care approach or wrong medication that can worsen the symptoms [10].”
In the citing paper
“To date, no FTD-specific diagnostic tests or disease-modifying treatments are available and misdiagnosis often leads to an unsuitable care approach or wrong medication that can worsen the symptoms [10].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hirono, N., Mori, E., Ikejiri, Y., Imamura, T., Shimomura, T., Hashimoto, M., Yamashita, H., & Ikeda, M. (1997) · PubMed · Cited by 21,012
Kok, J. S., Berg, I. J., & Scherder, E. J. A. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000353441 · Cited by 20,589
The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia
Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., & Gornbein, J. (1994) · Neurology · doi:10.1212/wnl.44.12.2308 · Cited by 7,568
Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria
Neary, D., Snowden, J. S., Gustafson, L., Passant, U., Stuss, D., Black, S., Freedman, M., Kertesz, A., Robert, P. H., Albert, M., et al. (1998) · Neurology · doi:10.1212/wnl.51.6.1546 · Cited by 5,047
Weıntraub, S. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530120075013 · Cited by 3,018
Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups.
(1994) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.4.416 · Cited by 1,331
The prevalence of frontotemporal dementia
Ratnavalli, E., Brayne, C., Dawson, K. E., & Hodges, J. R. (2002) · Neurology · doi:10.1212/wnl.58.11.1615 · Cited by 1,182
Cerebral Glucose Metabolism in Adults with Hyperactivity of Childhood Onset
Zametkin, A. J., NORDAHL, T. E., Gross, M., King, A. C., Semple, W. E., Rumsey, J. M., Hamburger, S., & Cohen, R. M. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011153232001 · Cited by 975
Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia: A Review of the Evidence
Sink, K. M., Holden, K. F., & Yaffe, K. (2005) · JAMA · doi:10.1001/jama.293.5.596 · Cited by 910
Sunderland, T., Linker, G., Mirza, N., Putnam, K. T., Friedman, D. L., Kimmel, L. H., Bergeson, J., Manetti, G. J., Zimmermann, M., Tang, B., et al. (2003) · JAMA · doi:10.1001/jama.289.16.2094 · Cited by 656
Self-citation
Cited by
Sorted by citations
Items 201–299 of 299
Adler, G., & Mautes, A. E. M. (2014) · Geriatric Mental Health Care · doi:10.1016/j.gmhc.2014.06.001 · Cited by 5
Zide, B. S., Barker, M. S., Silverman, H. E., Manoochehri, M., Fremont, R., Stein, C. M., Kunicki, Z. J., Lee, S., Devanand, D. P., & Huey, E. D. (2025) · International Review of Psychiatry · doi:10.1080/09540261.2025.2572365 · Cited by 4
Self-citationBaborie, A., Jaros, E., Griffiths, T. D., Momeni, P., Perry, R., & Mann, D. M. A. (2011) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2011.01209.x · Cited by 4
Pasquier, F., Lebouvier, T., & Lebert, F. (2016) · Neuropsychiatric symptoms of neurological disease · doi:10.1007/978-3-319-39138-0_13 · Cited by 4
Behavior and Personality Disturbances
Gehl, C. R., & Paulsen, J. S. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0434-1.00008-6 · Cited by 4
GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration
Hughes, L. E., Adams, N., Rouse, M. A., Naessens, M., Shaw, A. D., Murley, A. G., Cope, T., Holland, N., Nesbitt, D. J., Street, D., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14531 · Cited by 7
Neuropsychiatric symptoms in behavioral variant frontotemporal dementia: a narrative review
Page, J., Pontone, G. M., & Davydow, D. S. (2025) · International Review of Psychiatry · doi:10.1080/09540261.2025.2583257 · Cited by 3
Effects of Prescribed Medications on Cognition and Behavior in Frontotemporal Lobar Degeneration
Irwin, D. J., Lippa, C. F., & Rosso, A. L. (2010) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317510382285 · Cited by 3
Piešťanský, J., Forgácsová, A., Olešová, D., Galba, J., Mikuš, P., Majerová, P., & Kováč, A. (2022) · Separations · doi:10.3390/separations9010016 · Cited by 3
Boeve, B. F., & Boxer, A. L. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511581410.016 · Cited by 3
Sleegers, K., & Broeckhoven, C. V. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6231-8.10056-x · Cited by 3
Iyer, M. R., Zhao, B., He, X., Camacho, D., Wei, Z., Deng, J., & Mitchell, C. S. (2026) · Biomedicines · doi:10.3390/biomedicines14020444 · Cited by 2
Advancing Care in Alzheimer’s Disease: Current Treatments and Their Impact on Quality of Life
Yashaeva, L., Montoya, M., Joshi, J., Stephens, A., McNulty, O., & Kaur, G. (2025) · Cureus · doi:10.7759/cureus.90527 · Cited by 5
Bedoya, S. M., Cortina, S. C., Ruiz, I. G., & Suárez-Escudero, J. (2022) · Acta neurológica colombiana · doi:10.22379/24224022432
Suwanpasu, S. (2017) · Asian Biomedicine · doi:10.5372/1905-7415.0904.413 · Cited by 2
Les nouveaux traceurs TEMP et TEP de la démence
Vergote, J., Chalon, S., Emond, P., Vercouillie, J., Pappatà, S., & Guilloteau, D. (2009) · Médecine Nucléaire · doi:10.1016/j.mednuc.2009.01.005 · Cited by 2
van Domburg, P., Vromen, M., Collet, J., Durlinger, M., Roufs, S., Schols, J. M. G. A., Sipers, W. M. W. H., Verkaaik, M., & Verhey, F. R. J. (2013) · Tijdschrift voor Neuropsychiatrie en Gedragsneurologie · doi:10.1007/s40533-013-0009-3 · Cited by 2
The several faces of dementia syndrome: How to diagnose clinically?
Henrique, L., Fornari, T., Garcia, L. P., Hilbig, A., & Fernandez, L. L. (2010) · Cited by 2
Grover, S., Avasthi, A., & Gupta, G. (2016) · Journal of Geriatric Mental Health · doi:10.4103/2348-9995.181921 · Cited by 2
Arrant, A. E., & Roberson, E. D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801942-9.00006-9 · Cited by 3
Pourriyahi, H., Almasi‐Dooghaee, M., Imani, A., Vahedi, T., & Zamani, B. (2022) · Neurocase · doi:10.1080/13554794.2022.2105652 · Cited by 2
Anderl‐Straub, S., Schuster, J., Dorst, J., & Ludolph, A. C. (2021) · Der Nervenarzt · doi:10.1007/s00115-021-01209-7 · Cited by 2
Exercise, cognition and dementia
Scherder, E., & Eggermont, L. H. P. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9781316529898.019 · Cited by 2
Behavior and Personality Disturbances
Nehl, C., & Paulsen, J. S. (2008) · Elsevier eBooks · doi:10.1016/b978-0-7506-7525-3.50010-8 · Cited by 2
Tauopathy in the APP swe / PS1 ΔE9 mouse model of familial Alzheimer’s diseasePreprint
Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/405647 · Cited by 4
Behavioral Symptoms of Dementia
Volicer, L. (2018) · OBM Geriatrics · doi:10.21926/obm.geriatr.1804019 · Cited by 2
Neurotransmitter in the Aging Brain
Indahlastari, A., & Woods, A. J. (2021) · Springer eBooks · doi:10.1007/978-3-030-22009-9_679 · Cited by 2
Boxer, A. L. (2011) · Wiley eBooks · doi:10.1002/9781444344110.ch4 · Cited by 3
Behavioural rigidity as a transdiagnostic marker of nucleus accumbens dysfunction in dementia
Chen, T., Ahmed, R. M., Piguet, O., & Irish, M. (2026) · Brain · doi:10.1093/brain/awag095 · Cited by 1
Tauopathies and its therapeutic interventions in Alzheimer’s disease
Sonawane, S. K., Rangappa, N., Chidambaram, H., & Chinnathambi, S. (2026) · Advances in pharmacology · doi:10.1016/bs.apha.2025.12.001 · Cited by 1
Schizophrenia and frontotemporal dementia: distinct diseases with converging circuit dysfunctions
Casile, A., Sapienza, J., Vasciaveo, V., Barzon, B., Nasini, S., Guarato, G., Ave, C., Martini, F., Bosia, M., & Comai, S. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.04.003 · Cited by 1
Vercelletto, M., Boutoleau‐Bretonnière, C., Volteau, C., Puel, M., Auriacombe, S., Sarazin, M., Michel, B. F., Couratier, P., Thomas-Antérion, C., Verpillat, P., et al. (2010) · Revue Neurologique · doi:10.1016/s0035-3787(10)70020-5 · Cited by 1
Pharmacologictherapy for FTD and related disorders
Tsai, R. M., & Boxer, A. L. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781316091586.021 · Cited by 1
Pathological Validation of Animal Models of Dementia
Pirici, D. N., Broeckhoven, C. V., & Kumar‐Singh, S. (2010) · Neuromethods · doi:10.1007/978-1-60761-898-0_7 · Cited by 1
Management of Psychiatric Features in Frontotemporal Dementia
Starks, J., & Rosenbloom, M. H. (2017) · Psychiatric Annals · doi:10.3928/00485713-20170411-01 · Cited by 1
Sawyer, R. P., Shinagawa, S., & Miller, B. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813866-3.00003-5 · Cited by 1
(Neurobiology of) Dementia: Causes, Presentation, and Management
Bensamoun, D., Mouton, A., Ettore, É., Robert, P. H., & David, R. (2017) · Mental health and illness worldwide · doi:10.1007/978-981-10-2414-6_7 · Cited by 1
Amran, A. Y., Bukhbinder, A. S., & Schulz, P. E. (2022) · doi:10.1093/med/9780197574317.003.0018 · Cited by 1
Serotonin receptors - a potential target for the treatment of Alzheimer’s disease
Eremin, D. V., Kondaurova, E. M., Rodnyy, A. Y., Molobekova, K. A., Kudlay, D. A., & Naumenko, V. S. (2023) · Biochemistry (Moscow) · doi:10.31857/s0320972523120059 · Cited by 1
Kondaurova, E. M., Komarova, A. A., Ilchibaeva, T. V., Rodnyy, A. Y., Zalivina, E. A., & Naumenko, V. S. (2024) · Vavilov Journal of Genetics and Breeding · doi:10.18699/vjgb-24-45 · Cited by 1
Frontotemporal Dementia and Psychiatric Symptoms
Onur, E., & Yalinay, P. (2011) · Dusunen Adam The Journal of Psychiatry and Neurological Sciences · doi:10.5350/dajpn2011240309 · Cited by 1
Frontotemporal Dementia (FTD) 2011
Kertesz, A. (2011) · Acta Neuropsychologica · doi:10.5604/01.3001.0001.0773 · Cited by 3
Pick-Komplex und andere fokale Hirnatrophien
Danek, A., Wekerle, G., & Neumann, M. (2008) · Springer eBooks · doi:10.1007/978-3-540-35486-4_8 · Cited by 1
(2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781316091586.006 · Cited by 1
Anderson, N. H., & Woodburn, K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-7020-3137-3.00022-x · Cited by 1
Behavior Symptoms in Primary Progressive Aphasia Variants
Maruta, C., Marôco, J. P., de Mendonça, A., & Guerreiro, M. (2016) · Neuropsychiatric symptoms of neurological disease · doi:10.1007/978-3-319-39138-0_3 · Cited by 2
Frontotemporale Demenz (Pick-Komplex)
Nagy, R., Heuckmann, J., Mennel, H.-D., Klosterkötter, J., & Kuhn, J. (2007) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-007-1108-2 · Cited by 1
FTLD targets brain regions expressing recently evolved genesPreprint
Pasquini, L., Pereira, F. L., Seddighi, S., Zeng, Y., Wei, Y., Illán‐Gala, I., Vatsavayai, S. C., Friedberg, A., Lee, A. J., Brown, J. A., et al. (2023) · medRxiv · doi:10.1101/2023.10.27.23297687 · Cited by 1
GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degenerationPreprint
Hughes, L. E., Adams, N., Rouse, M. A., Naessens, M., Shaw, A. D., Murley, A. G., Cope, T., Holland, N., Nesbitt, D. J., Street, D., et al. (2024) · medRxiv · doi:10.1101/2024.06.28.24309636 · Cited by 1
Neuropsychiatric Evaluation in Dementia
Marshall, G. A., & Cummings, J. L. (2008) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)01204-3
Die frontotemporale Lobärdegeneration: Ein Syndrom mit variabler klinischer Manifestation
Jesse, S., & Ac, L. (2011) · Journal für Kardiologie (Krause & Pachernegg GmbH)
Funcionalidade e desempenho cognitivo na demência frontotemporal variante comportamental
da Silva, T. B. L. (2013) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2013.tde-25032013-164625
Using Psychotropic Medications to Manage Problem Behaviors in Dementia
Wang, L. Y., & Raskind, M. A. (2013) · Wiley eBooks · doi:10.1002/9781118656082.ch8 · Cited by 1
Frontotemporal Lobar Degeneration
Schlachetzki, J. C. M. (2011) · InTech eBooks · doi:10.5772/28174
Irwin, D. J., & Lippa, C. F. (2010) · The Corsini Encyclopedia of Psychology · doi:10.1002/9780470479216.corpsy0685
Frontal Behavioral Symptoms in Prader-Willi Syndrome
Ogura, K., Fujii, T., & Mori, E. (2011) · Springer eBooks · doi:10.1007/978-0-387-92271-3_93
Quijano, T. D. S. (2007) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/s0211-3449(07)75477-2
Chronisch progrediente Aphasien
Verlag, S. M. (2009)
Dickerson, B. C. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781316091586.019
Evaluation and management of dementia
Collins, L., Rovner, B. W., & Collins-Fletcher, K. (2016) · Cambridge University Press eBooks · doi:10.1017/cbo9781107294967.010
Practicalmanagement of frontotemporal dementia
Huey, E. D., & Manoochehri, M. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781316091586.020
Self-citationNeuroimaging and Treatments Perspectives
Hoffmann, M. W. (2016) · Springer eBooks · doi:10.1007/978-3-319-33181-2_13
Hoffmann, M. W. (2016) · Springer eBooks · doi:10.1007/978-3-319-33181-2_12
Issac, T., & Chandra, S. R. (2016) · Journal of Geriatric Mental Health · doi:10.4103/2348-9995.195675
(Neurobiology of) Dementia: Causes, Presentation and Management
Bensamoun, D., Mouton, A., Ettore, É., Robert, P. H., & David, R. (2016) · Mental health and illness worldwide · doi:10.1007/978-981-10-0370-7_7-1
Motaghinejad, O., Motaghinejad, M., & Motevalian, M. (2017) · Advanced Biomedical Research · doi:10.4103/2277-9175.218026
Validação da escala de estadiamento e progressão da demência frontotemporal (FTD-FRS)
da Silva, T. B. L. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2018.tde-09052018-111153
Challenges of a frontotemporal dementia patient
Bryant, R., & Miller, C. (2018) · Geriatric Nursing · doi:10.1016/j.gerinurse.2018.10.009
The postsynaptic protein neurogranin: a new item in the Alzheimer’s disease biomarker toolbox
Kvartsberg, H. (2019) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Neurofilaments as biomarkers of neuronal damage
Pujol-Calderón, F. (2019)
[Current approaches to the treatment of fronto-temporal dementia].
Fedorova, Y. (2019) · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova · doi:10.17116/jnevro201911909218
Neurotransmitter in the Aging Brain
Indahlastari, A., & Woods, A. J. (2019) · Springer eBooks · doi:10.1007/978-3-319-69892-2_679-1
Implications for Treatment and Management
Hoffmann, M. W. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108589246.011
Depression bei Demenz: Wie gelingt die Behandlung?
Durgun, I., Falck, J., & Peters, O. (2021) · DNP - Der Neurologe und Psychiater · doi:10.1007/s15202-020-4613-2
Escitalopram for repeated stealing in an elderly man with an existing cerebral contusion
Mori, Y., & Ochiai, S. (2021) · Psychogeriatrics · doi:10.1111/psyg.12791
Johnson, N. (2018) · Springer eBooks · doi:10.1007/978-3-319-56782-2_507-2
Johnson, N. (2018) · Springer eBooks · doi:10.1007/978-3-319-57111-9_507
Hoffmann, M. W. (2016) · Springer eBooks · doi:10.1007/978-3-319-33181-2_1
Johnson, N. (2010) · Springer eBooks · doi:10.1007/978-0-387-79948-3_507
Gustafson, L., & Brun, A. E. (2012) · doi:10.1093/med/9780199696758.003.0043
Menschen mit Frontotemporaler Demenz: Versorgungsbedarfe und Interventionen
Dinand, C., Berwig, M., & Halek, M. (2022) · Springer eBooks · doi:10.1007/978-3-662-65204-6_10
Neary, D. (2010) · CRC Press eBooks · doi:10.1201/b13196-87
Roles of Nutraceuticals in Regulating Neurotransmitters in Dementia
Othman, N. F. F., Singh, G. K. S., & Hazalin, N. A. M. N. (2023) · Advances in Pharmacology and Pharmacy · doi:10.13189/app.2023.110201
Oh, K. C., Park, J. J., Yung, Y. B., Kim, B. Y., & Kim, J. E. (2023) · Journal of the Korean Neurological Association · doi:10.17340/jkna.2023.2.3
Major Neurocognitive Disorders Due to Frontotemporal Disease
Gopalakrishna, G., Sarangi, A., & Joshi, P. (2024) · Springer eBooks · doi:10.1007/978-3-031-55711-8_4
Sawyer, R. P., Doran, S., & Miller, B. L. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-19176-3.00032-7
Frontotemporal Dementia Associated with Behavioral and Psychotic Symptoms: Case Series
Aral, A. E., & Erdoğan, E. (2025) · İzmir Tıp Fakültesi Dergisi · doi:10.57221/izmirtip.1591976
Treatment of Frontotemporal Dementias
Chen, D., VandeVrede, L. A., & Boxer, A. L. (2025) · Cambridge University Press eBooks · doi:10.1017/9781108985055.022
Depression and apathy in frontotemporal dementia: a short assessment of facts and outlook
Jellinger, K. A. (2026) · Journal of Neural Transmission · doi:10.1007/s00702-025-03101-z
Elefante, C., Fustini, C., Lepri, V., Chicca, M. D., Coccoglioniti, A., Grosso, M. G., D'Alessandro, G., Tidona, S., Medda, P., Lattanzi, L., et al. (2026) · Journal of Ect · doi:10.1097/yct.0000000000001162
DIAGNOSTIC CHALLENGES AND CARE PATHWAYS IN YOUNG-ONSET DEMENTIA – A NARRATIVE REVIEW
Surosz, N., Myrny, A., Turlej, K., Kowalczuk, D., Kasianik, W., Lazitskaya, D., Sobchynskyi, M., Milasheuskaya, V., Kiełbaszewska, I., Miraniuk, K., et al. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.1(49).2026.4845
Boutoleau‐Bretonnière, C. (2015) · theses.fr (ABES) · doi:10.70675/85cf2bf3zce07z46cbzb836zf9cda8e7cde4
Katakami, S., Satake, Y., Taomoto, D., Okura, Y., Kobayashi, M., Takeda, K., Koizumi, F., Suehiro, T., Mori, K., Ikeda, M., et al. (2026) · Journal of Neural Transmission · doi:10.1007/s00702-026-03262-5
Chen, T., Sun, Q., Foxe, D., Narasimhan, M., Teng, C., Cheung, S. C., Carrick, J., Burrell, J. R., Hwang, Y. T., Ahmed, R. M., et al. (2026) · Journal of Neurology · doi:10.1007/s00415-026-14132-1
Vilella, D., Vitulli, A., Rollo, E., Logroscino, G., & Urso, D. (2026) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-026-01523-0
Zdunek, J., & Grodner, B. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27209094
Neurotransmitter-defined cerebral vulnerability patterns in frontotemporal lobar degeneration (FTLD)
Tahedl, M., Toomey, A., Mandal, N., Mangan, S., Siah, W. F., Tan, E., Hardiman, O., Kleinerova, J., McKenna, M. C., Hutchinson, S., et al. (2026) · Journal of Neurology · doi:10.1007/s00415-026-14216-y
Metadata
- Authors
- Huey, E. D., Putnam, K. T., & Grafman, J.
- Affiliations
- National Institutes of Health (US)
- Venue
- Neurology
- Published
- 2006-01-10
- Volume
- 66
- Issue
- 1
- Pages
- 17-22
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- PMC
- PMC4499854
- OpenAlex
- W2148211031
- Cited by
- 299
- References
- 84
- Citations by year
- 2026: 12 · 2025: 11 · 2024: 9 · 2023: 12 · 2022: 11 · 2021: 20 · 2020: 10 · 2019: 14 · 2018: 11 · 2017: 16 · 2016: 20 · 2015: 10 · 2014: 15 · 2013: 18 · 2012: 17
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (Z01NS002792)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Keywords
- frontotemporal dementia, neurotransmitter deficits, serotonin, dopamine, acetylcholine, antidepressants, behavioral symptoms, cognitive symptoms, treatment efficacy
- MeSH terms
- Antidepressive Agents, Brain, Clinical Trials as Topic, Dementia, Dopamine, Humans, Serotonin, Dopamine Agents, Treatment Outcome, Serotonin Receptor Agonists, Neurotransmitter Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review