Healthy diet and lifestyle and risk of stroke in a prospective cohort of women
Open accessAbstract
OBJECTIVE: To investigate the association between a low-risk lifestyle and risk of stroke. METHODS: The study population comprised 31,696 women, in the population-based Swedish Mammography Cohort who at baseline had completed a questionnaire about diet and lifestyle and were free from cardiovascular disease and cancer. We defined a low-risk lifestyle as a healthy diet (top 50% of a Recommended Food Score), moderate alcohol consumption (5-15 g/d), never smoking, physically active (walking/bicycling ≥40 min/d and exercise ≥1 h/wk), and body mass index below 25 kg/m(2). Stroke cases were identified from the Swedish National Patient Register and the Swedish Cause of Death Register. RESULTS: We ascertained 1,554 incident stroke cases, including 1,155 cerebral infarctions, 246 hemorrhagic strokes, and 153 unspecified strokes during 10.4 years of follow-up. The risk of stroke, in particular cerebral infarction, decreased steadily with increasing number of low-risk lifestyle factors. Compared with no low-risk factors, the multivariable relative risks (95% confidence interval) of cerebral infarction across increasing number of low-risk factors (1-5) were 0.72 (0.56-0.93), 0.67 (0.52-0.85), 0.57 (0.44-0.74), 0.54 (0.40-0.73), and 0.38 (0.20-0.73). CONCLUSIONS: These findings indicate that a low-risk lifestyle can substantially reduce the risk of stroke, especially cerebral infarction.
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Lichtenstein, A. H., Appel, L. J., Brands, M., Carnethon, M., Daniels, S., Franch, H. A., Franklin, B., Kris-Etherton, P., Harris, W. S., Howard, B., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176158 · Cited by 2,705 · see citing works
Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., et al. (2014) · Stroke · doi:10.1161/str.0000000000000046 · Cited by 2,650 · see citing works
Optimal Diets for Prevention of Coronary Heart Disease
Hu, F. B. (2002) · JAMA · doi:10.1001/jama.288.20.2569 · Cited by 1,503 · see citing works
Goldstein, L. B., Bushnell, C. D., Adams, R. J., Appel, L. J., Braun, L. T., Chaturvedi, S., Creager, M. A., Culebras, A., Eckel, R. H., Hart, R. G., et al. (2011) · Stroke · doi:10.1161/str.0b013e3181fcb238 · Cited by 1,306 · see citing works
Physical activity and risk of cardiovascular disease—a meta-analysis of prospective cohort studies
Li, J., & Siegrist, J. (2012) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph9020391 · Cited by 674 · see citing works
Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ · doi:10.1136/bmj.g4164 · Cited by 669 · see citing works
A Prospective Study of Diet Quality and Mortality in Women
Kant, A. K. (2000) · JAMA · doi:10.1001/jama.283.16.2109 · Cited by 571 · see citing works
Excess Body Weight and Incidence of Stroke
Strazzullo, P., D’Elia, L., Cairella, G., Garbagnati, F., Cappuccio, F. P., & Scalfi, L. (2010) · Stroke · doi:10.1161/strokeaha.109.576967 · Cited by 505 · see citing works
Primary Prevention of Stroke by Healthy Lifestyle
Chiuve, S. E., Rexrode, K. M., Spiegelman, D. L., Logroscino, G., Manson, J. E., & Rimm, E. B. (2008) · Circulation · doi:10.1161/circulationaha.108.781062 · Cited by 496 · see citing works
Light alcohol drinking and cancer: a meta-analysis
Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., Scotti, L., Jenab, M., Turati, F., Pasquali, E., et al. (2013) · Annals of Oncology · doi:10.1093/annonc/mds337 · Cited by 424 · see citing works
Patra, J., Taylor, B., Irving, H. M., Roerecke, M., Baliunas, D. O., Mohapatra, S., & Rehm, J. T. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-258 · Cited by 397 · see citing works
Messerer, M., Wolk, A., & Johansson, S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.7.1800 · Cited by 279 · see citing works
Self-citationHealthy lifestyle and the risk of stroke in women
Kurth, T., Moore, S. C., Gaziano, J. M., Kase, C. S., Stampfer, M. J., Berger, K., & Buring, J. E. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.13.1403 · Cited by 246 · see citing works
Low-Risk Diet and Lifestyle Habits in the Primary Prevention of Myocardial Infarction in Men
Åkesson, A., Larsson, S. C., Discacciati, A., & Wolk, A. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.06.1190 · Cited by 216 · see citing works
Self-citationÅkesson, A., Weismayer, C., Newby, P. K., & Wolk, A. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.19.2122 · Cited by 158 · see citing works
Self-citationLifestyle Factors on the Risks of Ischemic and Hemorrhagic Stroke
Zhang, Y. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.443 · Cited by 154 · see citing works
A prospective study of variety of healthy foods and mortality in women
Michels, K. B., & Wolk, A. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.4.847 · Cited by 152 · see citing works
Self-citationAlcohol and ischaemic heart disease: probably no free lunch
Jackson, R., Broad, J., CONNOR, J. L., & Wells, S. J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67770-7 · Cited by 125 · see citing works
Eguchi, E., Iso, H., Tanabe, N., Wada, Y., Yatsuya, H., Kikuchi, S., Inaba, Y., & Tamakoshi, A. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr429 · Cited by 121 · see citing works
Red Meat Consumption and Risk of Stroke in Swedish Women
Larsson, S. C., Virtamo, J. R. K., & Wolk, A. (2010) · Stroke · doi:10.1161/strokeaha.110.596510 · Cited by 67 · see citing works
Self-citationDietary supplement use and mortality in a cohort of Swedish men
Messerer, M., Håkansson, N., Wolk, A., & Åkesson, A. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507812049 · Cited by 43 · see citing works
Self-citationOverall diet quality and risk of stroke: A prospective cohort study in women
Larsson, S. C., Åkesson, A., & Wolk, A. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.11.072 · Cited by 22 · see citing works
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Madsen, T. E., Samaei, M., Pikula, A., Yu, A. Y. X., Carcel, C., Millsaps, E., Yalamanchili, R. S., Bencie, N., Dula, A. N., Leppert, M., et al. (2022) · Clinical Therapeutics · doi:10.1016/j.clinthera.2022.02.006 · Cited by 27 · see citing works
- Authors
- Larsson, S. C., Åkesson, A., & Wolk, A.
- Affiliations
- Karolinska Institutet (SE)
- Corresponding author
- Larsson, Susanna C.
- Venue
- Neurology
- Published
- 2014-11-04
- Volume
- 83
- Issue
- 19
- Pages
- 1699-1704
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- PMC
- PMC4239835
- OpenAlex
- W2135615985
- Semantic Scholar
- 58f9303de22cf46a23df90946536cea0e4b2bf4d
- Cited by
- 117
- References
- 22
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 10 · 2023: 7 · 2022: 7 · 2021: 11 · 2020: 7 · 2019: 8 · 2018: 11 · 2017: 18 · 2016: 13 · 2015: 14
- FWCI
- 10.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Neurology (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Keywords
- stroke, cerebral infarction, hemorrhagic stroke, healthy eating, lifestyle factors, alcohol consumption, physical activity, never smoking, body mass index, women, Swedish Mammography Cohort
- MeSH terms
- Aged, Aged, 80 and over, Alcohol Drinking, Cardiovascular Diseases, Diet, Feeding Behavior, Female, Humans, Life Style, Surveys and Questionnaires, Risk Factors, Smoking, Sweden, Cohort Studies, Proportional Hazards Models, Women's Health, Stroke
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