The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Generalizability: The trees, the forest, and the low-hanging fruit
Open accessAbstract
Clinical and epidemiologic investigations are paying increasing attention to the critical constructs of "representativeness" of study samples and "generalizability" of study results. This is a laudable trend and yet, these key concepts are often misconstrued and conflated, masking the central issues of internal and external validity. The authors define these issues and demonstrate how they are related to one another and to generalizability. Providing examples, they identify threats to validity from different forms of bias and confounding. They also lay out relevant practical issues in study design, from sample selection to assessment of exposures, in both clinic-based and population-based settings.
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Cites
Guskiewicz, K. M., Marshall, S. W., Bailes, J., McCrea, M., Cantu, R. C., Randolph, C., & Jordan, B. D. (2005) · Neurosurgery · doi:10.1227/01.neu.0000175725.75780.dd · Cited by 1,197
Documented head injury in early adulthood and risk of Alzheimer’s disease and other dementias
Plassman, B. L., Havlik, R. J., Steffens, D. C., Helms, M. J., Newman, T. N., Drosdick, D., Phillips, C., Gau, B. A., Welsh–Bohmer, K. A., Burke, J. R., et al. (2000) · Neurology · doi:10.1212/wnl.55.8.1158 · Cited by 896
Mortimer, J. A., Van Duijn, C. M., Chandra, V, Fratiglioni, L., Graves, A. B., Heyman, A., Jorm, A. F., Kokmen, E., Kondo, K., Rocca, W. A., et al. (1991) · International Journal of Epidemiology · doi:10.1093/ije/20.supplement_2.s28 · Cited by 594
Representative Sampling, III: The Current Statistical Literature
Kruskal, W., & Mosteller, F. (1979) · International Statistical Review / Revue Internationale de Statistique · doi:10.2307/1402647 · Cited by 194
Farrer, L. A. (1997) · JAMA · doi:10.1001/jama.1997.03550160069041 · Cited by 124
Smoking, Death, and Alzheimer Disease: A Case of Competing Risks
Chang, C.-C. H., Zhao, Y., Lee, C.-W., & Ganguli, M. (2012) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e3182420b6e · Cited by 85
Self-citationTsuang, D., Kukull, W., Sheppard, L., Barnhart, R. L., Peskind, E., Edland, S. D., Schellenberg, G., Raskind, M., & Larson, E. B. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb01836.x · Cited by 69
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Cited by
Constraints on Generality (COG): A Proposed Addition to All Empirical Papers
Simons, D. J., Shoda, Y., & Lindsay, D. S. (2017) · Perspectives on Psychological Science · doi:10.1177/1745691617708630 · Cited by 986
Challenges to Online Medical Education During the COVID-19 Pandemic
Rajab, M. H., Gazal, A. M., & Alkattan, K. (2020) · Cureus · doi:10.7759/cureus.8966 · Cited by 594
Using Network Analysis to Identify Central Symptoms of Adolescent Depression
Mullarkey, M. C., Marchetti, I., & Beevers, C. G. (2019) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2018.1437735 · Cited by 484
Davis, A. C., Voelkel, J. L., Remmers, C. L., Adams, J. L., & McGlynn, E. A. (2023) · The Permanente Journal · doi:10.7812/tpp/22.172 · Cited by 402
Moshontz, H., Campbell, L., Ebersole, C. R., IJzerman, H., Urry, H. L., Forscher, P. S., Grahe, J. E., McCarthy, R. J., Musser, E. D., Antfolk, J., et al. (2018) · Advances in Methods and Practices in Psychological Science · doi:10.1177/2515245918797607 · Cited by 377
Metadata
- Authors
- Kukull, W. A., & Ganguli, M.
- Venue
- Neurology
- Published
- 2012-06-05
- Volume
- 78
- Issue
- 23
- Pages
- 1886-1891
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2019491759
- Cited by
- 239
- References
- 7
- FWCI
- 3.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kukull, W. A., & Ganguli, M. (2012). Generalizability: The trees, the forest, and the low-hanging fruit. Neurology. https://doi.org/10.1212/wnl.0b013e318258f812
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
