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The incidence of cerebral amyloid angiopathy in Alzheimer's disease
Abstract
The incidence and forms of cerebral amyloid angiopathy were studied in 15 cases of Alzheimer's disease using Congo red staining and polarization. Thirteen cases showed slight to severe involvement; two contained no amyloid vascular degeneration. There was a correlation between the presence of amyloid-rich plaques and cerebral amyloid angiopathy (especially the plaque-like angiopathy) but no correlation with "amyloid-poor" senile plaques or Alzheimer's neurofibrillary degeneration.
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Citations
Cited by
Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus
Tanzi, R. E., Gusella, J. F., Watkins, P. C., Bruns, G. A. P., St George-Hyslop, P., Van Keuren, M. L., Patterson, D., Pagan, S., Kurnit, D. M., & Neve, R. L. (1987) · Science · doi:10.1126/science.2949367 · Cited by 1,611
Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., & Roses, A. D. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.20.9649 · Cited by 1,525
Pathogenesis of Leukoaraiosis: A Review
Pantoni, L., & Garcia, J. H. (1997) · Stroke · doi:10.1161/01.str.28.3.652 · Cited by 1,225
Normal and Abnormal Biology of the beta-Amyloid Precursor Protein
Selkoe, D. J. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.002421 · Cited by 818
Cerebral amyloid angiopathy without and with cerebral hemorrhages: A comparative histological study
Vonsattel, J. P. G., Myers, R. H., Tessa Hedley‐Whyte, E., Ropper, A. H., Bird, E. D., & Richardson, E. P. (1991) · Annals of Neurology · doi:10.1002/ana.410300503 · Cited by 662
Metadata
- Authors
- MANDYBUR, T. I.
- Venue
- Neurology
- Published
- 1975-02
- Volume
- 25
- Issue
- 2
- Pages
- 120-120
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2072554237
- Cited by
- 286
- References
- 0
- FWCI
- 4.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- MANDYBUR, T. I. (1975). The incidence of cerebral amyloid angiopathy in Alzheimer's disease. Neurology. https://doi.org/10.1212/wnl.25.2.120
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
