The DOI matches its Crossref record.
Mild cognitive impairment in the elderly: Predictors of dementia
Abstract
We conducted full diagnostic evaluations, including a comprehensive cognitive assessment battery, of a group of 32 elderly subjects with a clinically identified mild cognitive impairment and a group of 32 age-matched and education-matched normal subjects. The mildly impaired subjects performed significantly more poorly than the controls on tests of recent memory, remote memory, language function, concept formation, and visuospatial praxis. Follow-up evaluations of cognitive status 2 years later revealed clinically detectable cognitive decline relative baseline in 23 (72%) of the mildly impaired subjects. Several of the objective psychological tests accurately discriminated at baseline between the decliners and nondecliners in the mildly impaired group. Among the 20 mildly impaired subjects with no complicating conditions, 16 exhibited cognitive deterioration between baseline and follow-up. These results suggest that most elderly subjects with mild cognitive deficits, as determined by clinical evaluation and objective psychological testing, will manifest the progressive mental deterioration characteristic of dementia and that psychometric predictors can be used to distinguish between benign and more significant underlying disorders in mildly impaired elderly subjects.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This intermediate state has been termed mild cognitive impairment (MCI) and clinical criteria for this diagnosis have been suggested(1–3).”
From Rates of hippocampal atrophy correlate with change in clinical status in aging and AD (2000) · cites this paper as [3]
Citations
Cited by
Sorted by citations
Items 201–300 of 839
Modeling the prevalence and incidence of Alzheimer’s disease and mild cognitive impairment
Yesavage, J. A., O'Hara, R. M., KRAEMER, H. C., Noda, A. M., Taylor, J. L., Ferris, S. H., Gély-Nargeot, M.-C., Rosen, A. C., Friedman, L., Sheikh, J. I., et al. (2002) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(02)00020-1 · Cited by 109
“Over the last 30 years, there have been a number of systems proposed for classifying older adults who suffer some degree of cognitive impairment or decline but do not yet meet criteria for Alzheimer’s disease (AD) (Blackford and La Rue, 1989; Crook et al., 1986; Flicker et al., 1991; Kral, 1962; Levy, 1994; Petersen e…”
BackgroundSelf-citationCSF Aβ42, Tau and phosphorylated Tau, APOE ɛ4 allele and MCI type in progressive MCI
Herukka, S., Helisalmi, S., Hallikainen, M., Tervo, S., Soininen, H. S., & Pirttilä, T. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.02.001 · Cited by 113
Current Epidemiology of Mild Cognitive Impairment and Other Predementia Syndromes
Panza, F., D’Introno, A., Colacicco, A. M., Capurso, C. A., Parigi, A. D., Caselli, R. J., Pilotto, A., Argentieri, G., Scapicchio, P. L., Scafato, E., et al. (2005) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.13.8.633 · Cited by 276
Dementia and mild cognitive impairment in adults with intellectual disability: Issues of diagnosis
Krinsky‐McHale, S. J., & Silverman, W. P. (2013) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.1126 · Cited by 116
Mitchell, J., Arnold, R. J., Dawson, K., Nestor, P. J., & Hodges, J. R. (2009) · Journal of Neurology · doi:10.1007/s00415-009-5152-0 · Cited by 109
Babiloni, C., Cassetta, E., Binetti, G. G., Tombini, M., Percio, C. D., Ferreri, F., Ferri, R., Frisoni, G. B., Lanuzza, B., Nobili, F. M., et al. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05601.x · Cited by 105
Palsetia, D., Rao, G. P., Tiwari, S. C., Lodha, P., & Sousa, A. D. (2018) · Indian Journal of Psychological Medicine · doi:10.4103/ijpsym.ijpsym_244_17 · Cited by 109
Magnetization Transfer Ratio in Mild Cognitive Impairment and Dementia of Alzheimer's Type
Kabani, N. J., Sled, J. G., & Chertkow, H. M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0992 · Cited by 103
Jicha, G. A., & Carr, S. A. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1237 · Cited by 107
Metabolism of amyloid β peptide and pathogenesis of Alzheimer's disease
Saido, T. C., & Iwata, N. (2006) · Neuroscience Research · doi:10.1016/j.neures.2005.12.015 · Cited by 102
Nutritional factors, cognitive decline, and dementia
Parigi, A. D., Panza, F., Capurso, C. A., & Solfrizzi, V. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.09.020 · Cited by 103
Global measures: utility in defining and measuring treatment response in dementia
Reisberg, . (2007) · International Psychogeriatrics · doi:10.1017/s1041610207005261 · Cited by 101
Self-citationStudzinski, C. M., Araujo, J. A., & Milgram, N. W. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.12.014 · Cited by 99
de Jager, C. A., & Budge, M. M. (2005) · Neurocase · doi:10.1080/13554790490896820 · Cited by 99
Hippocampal atrophy and EEG markers in subjects with mild cognitive impairment
Moretti, D. V., Miniussi, C., Frisoni, G. B., Geroldi, C., Zanetti, O. O., Binetti, G. G., & Rossini, P. M. (2007) · Clinical Neurophysiology · doi:10.1016/j.clinph.2007.09.059 · Cited by 97
He, J., Farias, S. T., Martinez, O., Reed, B., Mungas, D., & DeCarli, C. S. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.252 · Cited by 99
Ihl, R., Frölich, L., Winblad, B. G., Schneider, L. S. S., Burns, A. S., Möller, H., & WFSBP Task Force on Treatment Guidelines for Alzheimer's Disease and other Dementias (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2010.538083 · Cited by 99
A brief history of “Alzheimer disease”
Knopman, D. S., Petersen, R. C., & Jack, C. R. (2019) · Neurology · doi:10.1212/wnl.0000000000007583 · Cited by 104
Padovani, A., Borroni, B., Colciaghi, F., Pettenati, C., Cottini, E., Agosti, C., Lenzi, G. L., Caltagirone, C., Trabucchi, M., Cattabeni, F., et al. (2002) · Archives of Neurology · doi:10.1001/archneur.59.1.71 · Cited by 96
Regulatory Objectivity in Action
Moreira, T., May, C. R., & Bond, J. (2009) · Social Studies of Science · doi:10.1177/0306312709103481 · Cited by 103
“The paper focuses on one such conventional standard: Mild Cognitive Impairment (MCI).”
BackgroundMethodInfluentialA Two-Year Longitudinal Study of Cognitive Function in Normal Aging and Alzheimer's Disease
Flicker, C., Ferris, S. H., & Reisberg, . (1993) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198879300600205 · Cited by 97
Self-citationVisuospatial Perception: An Emerging Biomarker for Alzheimer's Disease
Mandal, P. K., Joshi, J., & Saharan, S. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-120901 · Cited by 105
Mild cognitive impairment — an early stage of Alzheimer’s disease?
Almkvist, O., Basun, H., Bäckman, L., Herlitz, A., Lannfelt, L., Small, B. J., Viitanen, M. H., Wahlund, L., & Winblad, B. G. (1998) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-7508-8_3 · Cited by 96
Meta-Analysis of Cognition in Parkinson’s Disease Mild Cognitive Impairment and Dementia Progression
Wallace, E. R., Segerstrom, S. C., van Horne, C. G., Schmitt, F. A., & Koehl, L. (2021) · Neuropsychology Review · doi:10.1007/s11065-021-09502-7 · Cited by 98
Cognitive Impairment with No Dementia (CIND): Longitudinal Studies, the Findings, and the Issues
Tuokko, H. A., & Frerichs, R. J. (2000) · The Clinical Neuropsychologist · doi:10.1076/clin.14.4.504.7200 · Cited by 94
Mild cognitive impairment: experience from a memory clinic
Wahlund, L., Pihlstrand, E., & Eriksdotter, M. (2003) · Acta Neurologica Scandinavica · doi:10.1034/j.1600-0404.107.s179.3.x · Cited by 94
Mild Cognitive Impairment in Parkinson’s Disease—What Is It?
Weil, R. S., Costantini, A. A., & Schrag, A. E. (2018) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-018-0823-9 · Cited by 94
Babiloni, C., Benussi, L., Binetti, G. G., Cassetta, E., Forno, G. D., Percio, C. D., Ferreri, F., Ferri, R., Frisoni, G. B., Ghidoni, R., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20724 · Cited by 96
Rossini, P. M., Buscema, M., Capriotti, M., Grossi, E., Rodriguez, G., Percio, C. D., & Babiloni, C. (2008) · Clinical Neurophysiology · doi:10.1016/j.clinph.2008.03.026 · Cited by 91
“The present inclusion and exclusion criteria for amnesic MCI were based on previous seminal studies (Albert et al., 1991; Devanand et al., 1997; Flicker et al., 1991; Petersen et al., 1995, 1997, 2001; Rubin et al., 1989; Portet et al., 2006; Zaudig, 1992) defining elderly persons, who do not meet the criteria for a d…”
MethodOwsley, C. J. (2012) · Vision Research · doi:10.1016/j.visres.2012.11.014 · Cited by 92
Becerra, J., Fernández, T., Roca-Stappung, M., Dı́az-Comas, L., Galán, L., Bosch, J., Espino, M., Moreno, A. J., & Harmony, T. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-111055 · Cited by 89
Longitudinal analysis of abnormal domains comprising mild cognitive impairment (MCI) during aging
Meyer, J. S., Xu, G., Thornby, J. A., Chowdhury, M. H., & Quach, M. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00159-4 · Cited by 86
Yeung, M. K.-C., & Chan, A. S.-Y. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.02.017 · Cited by 87
Identification of Glycoproteins in Human Cerebrospinal Fluid with a Complementary Proteomic Approach
Pan, S., Wang, Y., Quinn, J. F., Peskind, E. R., Waichunas, D., Wimberger, J., Jin, J., Li, J. G., Zhu, D. C., Pan, C., et al. (2006) · Journal of Proteome Research · doi:10.1021/pr060251s · Cited by 87
Kantarci, K., Petersen, R. C., Przybelski, S. A., Weigand, S. D., Shiung, M. M., Whitwell, J. L., Negash, S., Ivnik, R. J., Boeve, B. F., Knopman, D. S., et al. (2008) · Archives of Neurology · doi:10.1001/archneur.65.12.1621 · Cited by 84
Perrotin, A., Belleville, S., & Isingrini, M. L. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.05.003 · Cited by 83
Mild cognitive impairment: cognitive screening or neuropsychological assessment?
Diniz, B. S., Nunes, P. V., Yassuda, M. S., et al. (2008) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462008000400003 · Cited by 86
Caroli, A., Testa, C., Geroldi, C., Nobili, F. M., Barnden, L. R., Guerra, U. P., Bonetti, M., & Frisoni, G. B. (2007) · Journal of Neurology · doi:10.1007/s00415-007-0631-7 · Cited by 85
McDonald, M. P., & Overmier, J. B. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00024-9 · Cited by 87
Yamamoto, Y., Akiguchi, I., Oiwa, K., Hayashi, M., Kasai, T., & Ozasa, K. (2002) · Stroke · doi:10.1161/str.33.1.297 · Cited by 82
Babiloni, C., Lizio, R., Vecchio, F., Frisoni, G. B., Pievani, M., Geroldi, C., Fracassi, C., Ferri, R., Lanuzza, B., & Rossini, P. M. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100798 · Cited by 83
Attention and Memory in the Preclinical Stage of Dementia
Silveri, M. C., Reali, G., Jenner, C., & Puopolo, M. (2007) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988706297469 · Cited by 77
“The term mild cognitive impairment (MCI)(1) is one of several terms (eg, cognitive impairment/no dementia, isolated memory impairment, etc) that formally define the transitional cognitive status between normal aging and dementia.(2) Although the dementia would usually seem to pass through a preclinical stage in which…”
BackgroundMartin, S. B., Smith, C. D., Collins, H. R., Schmitt, F. A., & Gold, B. T. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.08.010 · Cited by 84
Babiloni, C., Benussi, L., Binetti, G. G., Bosco, P., Busonero, G., Cesaretti, S., Forno, G. D., Percio, C. D., Ferri, R., Frisoni, G. B., et al. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.08.030 · Cited by 81
Psychometric Properties of the Mattis Dementia Rating Scale
Smith, G. E., Ivnik, R. J., Malec, J. F., Kokmen, E., Tangalos, E. G., & Petersen, R. C. (1994) · Assessment · doi:10.1177/1073191194001002002 · Cited by 80
Kluger, A., Ferris, S. H., Reisberg, ., et al. (1997) · International Psychogeriatrics · doi:10.1017/s1041610297005048 · Cited by 80
Self-citationSanti, S. D., Pirraglia, E., Barr, W., Babb, J. S., Williams, S., Rogers, K., Glodzik, L., Bryś, M., Mosconi, L., Reisberg, ., et al. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.4.469 · Cited by 82
Self-citationShould mild cognitive impairment be subtyped?
Hughes, T. F., Snitz, B. E., & Ganguli, M. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328344696b · Cited by 87
Mild behavioral impairment: A prodromal stage of dementia
Taragano, F. E., Allegri, R., & Lyketsos, C. G. (2008) · Dementia & Neuropsychologia · doi:10.1590/s1980-57642009dn20400004 · Cited by 85
Didic, M., Félician, O., Barbeau, E. J., Mancini, J., Latger-Florence, C., Tramoni, E., & Ceccaldi, M. P. (2013) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000347203 · Cited by 88
Evidence That Age-Associated Memory Impairment Is Not a Normal Variant of Aging
Goldman, W. P., & Morris, J. C. (2001) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200104000-00006 · Cited by 77
“pairment and late-life forgetfulness (Blackford and La Rue, 1989), aging-associated cognitive decline (Levy, 1994), age-related cognitive decline (American Psychiatric Association, 1994), mild cognitive impairment (Flicker et al., 1991; Petersen, 1995), questionable dementia (Devanand et al.”
BackgroundBuscema, M., Rossini, P. M., Babiloni, C., & Grossi, E. (2007) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2007.02.006 · Cited by 77
Effects of sex and APOE ε4 on object recognition and spatial navigation in the elderly
Berteau-Pavy, F., Park, B., & Raber, J. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.03.005 · Cited by 85
Single- and Multiple-Domain Amnestic Mild Cognitive Impairment: Two Sides of the Same Coin
Brambati, S. M., Belleville, S., Kergoat, M., Chayer, C., Gauthier, S. G., & Joubert, S. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000255240 · Cited by 83
Are people with mild cognitive impairment aware of the benefits of errorless learning?
Akhtar, S., Moulin, C. J. A., & Bowie, P. C. W. (2006) · Neuropsychological Rehabilitation · doi:10.1080/09602010500176674 · Cited by 74
Conversion to Dementia among Two Groups with Cognitive Impairment
Luis, C. A., Barker, W., Loewenstein, D., Crum, T. A., Rogaeva, E. A., Kawarai, T., George‐Hyslop, P. S., & Duara, R. (2004) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000080124 · Cited by 78
‘Prodromal Alzheimerʼs disease’: a more useful concept than mild cognitive impairment?
Dubois, B. (2000) · Current Opinion in Neurology · doi:10.1097/00019052-200008000-00001 · Cited by 76
Verbal and nonverbal fluency in patients with probable Alzheimer's disease.
Mickanin, J., Grossman, M., Onishi, K., Auriacombe, S., & Clark, C. M. (1994) · Neuropsychology · doi:10.1037/0894-4105.8.3.385 · Cited by 77
Babiloni, C., Percio, C. D., Lizio, R., Marzano, N., Infarinato, F., Soricelli, A., Salvatore, E., Ferri, R., Bonforte, C., Tedeschi, G., et al. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.06.019 · Cited by 78
Proton MRS in mild cognitive impairment
Kantarci, K. (2013) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.23800 · Cited by 76
Babiloni, C., Pievani, M., Vecchio, F., Geroldi, C., Eusebi, F., Fracassi, C., Fletcher, E., De Carli, C., Boccardi, M., Rossini, P. M., et al. (2009) · Human Brain Mapping · doi:10.1002/hbm.20612 · Cited by 75
Screening for Memory Disorders, Dementia and Alzheimer’s Disease
Ashford, J. W. (2008) · Aging Health · doi:10.2217/1745509x.4.4.399 · Cited by 76
Santos, V. D., Thomann, P. A., Wüstenberg, T., Seidl, U., Essig, M., & Schröder, J. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100156 · Cited by 73
Hippocampal Atrophy Disrupts Transfer Generalization in Nondemented Elderly
Myers, C. E., Kluger, A., Golomb, J. B., Ferris, S. H., de Leon, M. J., Schnirman, G. M., & Gluck, M. A. (2002) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198870201500206 · Cited by 74
Self-citationLifshitz, M., Dwolatzky, T., & Press, Y. (2012) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988712457047 · Cited by 77
“Approximately 12% to 15% of elderly individuals who are diagnosed with MCI will develop dementia annually, and there is increasing interest in the early detection of cognitive changes and in the development of possible interventions for the at-risk population.(4,5) Although impaired memory is a characteristic feature…”
BackgroundEffects of a Goal-Oriented Rehabilitation Program in Mild Cognitive Impairment: A Pilot Study
Londos, E., Boschian, K., Lindén, A., Persson, C., Minthon, L., & Lexell, J. E. (2008) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317507312622 · Cited by 77
Shin, J., Han, S. D., & Choi, J. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16193767 · Cited by 73
“Patients with mild cognitive impairment have been shown to be at risk of developing Alzheimer’s disease and other neurodegenerative diseases [5,6].”
BackgroundThe cognitive syndrome of vascular dementia: implications for clinical trials
Desmond, D. W., Erkinjuntti, T., Sano, M., et al. (2022) · PubMed · doi:10.7916/037w-mc41 · Cited by 74
Self-citationShort latency afferent inhibition differs among the subtypes of mild cognitive impairment
Nardone, R., Bergmann, J., Christova, M., Caleri, F., Tezzon, F., Ladurner, G., Trinka, E., & Golaszewski, S. M. (2011) · Journal of Neural Transmission · doi:10.1007/s00702-011-0725-3 · Cited by 74
Living With Ambiguity: A Metasynthesis of Qualitative Research on Mild Cognitive Impairment
Gomersall, T., Astell, A., Nygård, L., Sixsmith, A., Mihailidis, A., & Hwang, A. (2015) · The Gerontologist · doi:10.1093/geront/gnv067 · Cited by 73
Eyeblink classical conditioning differentiates normal aging from Alzheimer’s disease
Woodruff‐Pak, D. S. (2001) · Integrative Psychological and Behavioral Science · doi:10.1007/bf02734044 · Cited by 73
Olfactory identification and apolipoprotein E ε4 allele in mild cognitive impairment
Wang, Q., Tian, L., Huang, Y., et al. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03137-2 · Cited by 73
Vliet, E. C.-V., Manly, J. J., Tang, M., Marder, K. S., Bell, K. L., & Stern, Y. (2003) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617703950053 · Cited by 77
Vascular damage and EEG markers in subjects with mild cognitive impairment
Moretti, D. V., Miniussi, C., Frisoni, G. B., Zanetti, O. O., Binetti, G. G., Geroldi, C., Galluzzi, S., & Rossini, P. M. (2007) · Clinical Neurophysiology · doi:10.1016/j.clinph.2007.05.009 · Cited by 72
López, O. L. (2013) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/01.con.0000429175.29601.97 · Cited by 84
“In addition, patients with MCI who presented with a demonstrable progression of their deficits were shown to be more likely to develop dementia than those whose deficits remained stable.(19) Indeed, the NIA-AA guidelines stated that support for the diagnosis of MCI could be provided by evidence of a decline on serial…”
BackgroundSalivary cortisol day profiles in elderly with mild cognitive impairment
Wolf, O. T., Convit, A. J., Thorn, E., & de Leon, M. J. (2002) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00079-8 · Cited by 70
Fractional Anisotropy of the Fornix and Hippocampal Atrophy in Alzheimer’s Disease
Kantarci, K. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00316 · Cited by 71
Learning potential: a new method for assessing cognitive impairment
Ballesteros, R. F., Zamarrón, M. D., & Tárraga, L. (2005) · International Psychogeriatrics · doi:10.1017/s1041610205000992 · Cited by 70
Chu, Y., Cochran, E. J., Bennett, D. A., Mufson, E. J., & Kordower, J. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1284 · Cited by 69
Tapp, P. D., Siwak, C. T., Estrada, J., Holowachuk, D., & Milgram, N. W. (2003) · Learning & Memory · doi:10.1101/lm.56503 · Cited by 71
Vecchio, F., Miraglia, F., Curcio, G., Altavilla, R., Scrascia, F., Giambattistelli, F., Quattrocchi, C. C., Bramanti, P., Vernieri, F., & Rossini, P. M. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-142484 · Cited by 68
Early detection of Alzheimer's disease using the Cambridge Cognitive Examination (CAMCOG)
Schmand, B. A., Walstra, G. J. M., Lindeboom, J., Teunisse, S., & Jonker, C. (2000) · Psychological Medicine · doi:10.1017/s0033291799002068 · Cited by 70
Mild cognitive impairment in Parkinson’s disease: Diagnosis and progression to dementia
Hernández, I. G., Nieto, A., Lorenzo, J. N., & Barroso, J. (2015) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2015.1087465 · Cited by 68
Memory deficits in Alzheimer's disease: The encoding hypothesis and cholinergic function
White, K. G., & Ruske, A. C. (2002) · Psychonomic Bulletin & Review · doi:10.3758/bf03196301 · Cited by 69
Autobiographical Memory Deficits in Alzheimer's Disease
Seidl, U., Lueken, U., Thomann, P. A., Geider, F. J., & Schröder, J. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-110014 · Cited by 79
Validity of the Mindstreams Computerized Cognitive Battery for Mild Cognitive Impairment
Dwolatzky, T., Whitehead, V., Doniger, G. M., Simon, E. S., Schweiger, A., Jaffe, D. H., & Chertkow, H. M. (2008) · Journal of Molecular Neuroscience · doi:10.1007/s12031-007-9031-9 · Cited by 68
Shin, D., Kwon, S. C., Kim, M. H., Lee, K. W., Choi, S. Y., Shivappa, N., Hébert, J. R., & Chung, H. (2018) · Nutrition · doi:10.1016/j.nut.2018.02.026 · Cited by 66
Mild cognitive impairment: historical development and summary of research
Golomb, J. B., Kluger, A., & Ferris, S. H. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.4/jgolomb · Cited by 69
Self-citationThe Role of Hypoxia-Inducible Factor 1 in Mild Cognitive Impairment
Iyalomhe, O., Swierczek, S. I., Enwerem, N. Y., Chen, Y., Adedeji, M. O., Allard, J. S., Ntekim, O. E., Johnson, S. M., Hughes, K., Kurian, P., et al. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0440-6 · Cited by 64
“I am active”: effects of a program to promote active aging
Mendoza-Ruvalcaba, N. M., & Arias‐Merino, E. D. (2015) · Clinical Interventions in Aging · doi:10.2147/cia.s79511 · Cited by 67
Statins of Different Brain Penetrability Differentially Affect CSF PLTP Activity
Vuletic, S., Riekse, R. G., Marcovina, S. M., Peskind, E. R., Hazzard, W. R., & Albers, J. J. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000095679 · Cited by 66
Quantitative EEG Markers in Mild Cognitive Impairment: Degenerative versus Vascular Brain Impairment
Moretti, D. V., Zanetti, O. O., Binetti, G. G., & Frisoni, G. B. (2012) · International Journal of Alzheimer s Disease · doi:10.1155/2012/917537 · Cited by 64
Taffe, M. A., Weed, M. R., Gutierrez, T., Davis, S. A., & Gold, L. H. (2002) · Psychopharmacology · doi:10.1007/s00213-001-0954-5 · Cited by 67
Mild Cognitive Impairment and Dementia
Albert, M., & Blacker, D. (2006) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.144039 · Cited by 65
Measuring cognitive change in subjects with prodromal Alzheimer’s disease
Mura, T., Proust-Lima, C., Jacqmin-Gadda, H., Akbaraly, T. N., Touchon, J., Dubois, B., & Berr, C. (2014) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2013-305078 · Cited by 64
Perry, R. J., & Hodges, J. R. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02754.x · Cited by 65
Krinsky‐McHale, S. J., Devenny, D. A., Kittler, P. M., & Silverman, W. P. (2008) · American Journal on Mental Retardation · doi:10.1352/2008.113:369-386 · Cited by 69
“It is noteworthy that investigators have found that conversion rates increase to 40% to 60% when memory impairment is accompanied by decline in additional cognitive abilities (e.g., Bozoki et al., 2001; Flicker et al., 1991; Morris et al., 2001; Petersen, 2004; Petersen et al., 2001).”
BackgroundDougherty, J. H., Cannon, R. L., Nicholas, C. R. N., Hall, L., Hare, F., Carr, E. R., Dougherty, A., Janowitz, J., & Arunthamakun, J. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1354 · Cited by 66
Mild Cognitive Impairment: Potential Pharmacological Treatment Options
Sherwin, B. B. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb04703.x · Cited by 67
Early Intervention Is Key to Successful Management of Alzheimer Disease
DeKosky, S. T. (2003) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200307004-00004 · Cited by 63
“In addition to studies on vitamin E, the use of Ginkgo biloba extracts, another antioxidant, may prove beneficial in the delay of progression of AD.49,50 Other agents that warrant attention are nonsteroidal antiinflammatory drugs, estrogen, and glutamate receptor modulators.”
BackgroundInfluential
Metadata
- Authors
- Flicker, C., Ferris, S. H., & Reisberg, B.
- Affiliations
- NYU Langone Health (US)
- Venue
- Neurology
- Published
- 1991-07
- Volume
- 41
- Issue
- 7
- Pages
- 1006-1006
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2008180577
- Cited by
- 838
- References
- 0
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 14 · 2023: 14 · 2022: 10 · 2021: 18 · 2020: 24 · 2019: 28 · 2018: 19 · 2017: 18 · 2016: 21 · 2015: 32 · 2014: 23 · 2013: 28 · 2012: 31
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh040410-02)
- National Institute on Aging (AG03051, R01AG003051)
- National Institute of Mental Health (MH 40410)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- mild cognitive impairment, older adults, cognitive decline, dementia, memory impairment, language functions, concept formation, cognitive assessment, longitudinal follow-up
- MeSH terms
- Aged, Aging, Cognition Disorders, Dementia, Humans, Longitudinal Studies, Neuropsychological Tests, Prognosis, Psychiatric Status Rating Scales
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
