The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
A Magnetization Transfer Imaging Study of Normal-Appearing White Matter in Multiple Sclerosis
Abstract
We attempted to define the role of subtle changes in the normal-appearing white matter (NAWM) in the development of disability in multiple sclerosis (MS). Twenty-seven clinically definite MS patients with either relapsing-remitting or chronic-progressive courses and 10 sex- and age-matched controls entered the study. For each patient and control, we studied two NAWM areas in the frontal lobe with magnetization transfer imaging (MTI). For patients, we also calculated the MT ratios (MTRs) for three contiguous areas of NAWM progressively further from "isolated" lesions visible on conventional MRI. Frontal NAWM in MS patients had lower mean MTRs than the frontal white matter of the controls (p = 0.02). MTRs in the NAWM adjacent to isolated lesions increased with distance from them to the cortical gray matter (p = 0.04). This pattern was typical for patients with chronic-progressive MS whose MTRs in the first two regions of NAWM adjacent to lesions were lower than those of the same regions of patients with relapsing-remitting MS. This study confirms that there are alterations in the NAWM of MS patients and suggests that such changes might be relevant to the disability in MS.
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Self-citationMajor differences in the dynamics of primary and secondary progressive multiple sclerosis
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DIAGNOSIS AND CLASSIFICATION OF MULTIPLE SCLEROSIS
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THE NECK-EYE REFLEX IN PATIENTS WITH REDUCED VESTIBULAR AND OPTOKINETIC FUNCTION
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Filippi, M., Rocca, M. A., Martino, G., Horsfield, M. A., & Comi, G. (1998) · Annals of Neurology · doi:10.1002/ana.410430616 · Cited by 395
Self-citationInvestigation of MS normal-appearing brain using diffusion tensor MRI with clinical correlations
Ciccarelli, O., Werring, D. J., Wheeler–Kingshott, C. A. M., Barker, G. J., Parker, G. J. M., Thompson, A. J., & Miller, D. H. (2001) · Neurology · doi:10.1212/wnl.56.7.926 · Cited by 349
Insights into brain microstructure from the T2 distribution
MacKay, A., Laule, C., Vavasour, I., Bjarnason, T., Kolind, S., & Mädler, B. (2006) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2005.12.037 · Cited by 347
Magnetic Resonance Imaging of Myelin
Laule, C., Vavasour, I. M., Kolind, S. H., Li, D. K. B., Traboulsee, T. L., Moore, G. R. W., & MacKay, A. L. (2007) · Neurotherapeutics · doi:10.1016/j.nurt.2007.05.004 · Cited by 334
Metadata
- Authors
- Filippi, M., Campi, A., Dousset, V., Baratti, C., Martinelli, V., Canal, N., Scotti, G., & Comi, G.
- Venue
- Neurology
- Published
- 1995-03
- Volume
- 45
- Issue
- 3
- Pages
- 478-482
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2058784068
- Cited by
- 366
- References
- 18
- FWCI
- 10.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Magnetization Transfer Imaging Study of Normal-Appearing White Matter in Multiple Sclerosis. https://app.cochat.ai/papers/10.1212/wnl.45.3.478
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- Filippi, M., Campi, A., Dousset, V., Baratti, C., Martinelli, V., Canal, N., Scotti, G., & Comi, G. (1995). A Magnetization Transfer Imaging Study of Normal-Appearing White Matter in Multiple Sclerosis. Neurology. https://doi.org/10.1212/wnl.45.3.478
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
