Magnetic Resonance Imaging of Myelin

Laule, Cornelia; Vavasour, Irene M.; Kolind, Shannon H.; Li, David K.B.; Traboulsee, Tony L.; Moore, G.R. Wayne; MacKay, Alex L.

doi:10.1016/j.nurt.2007.05.004

Cited by 334Advanced Neuroimaging Techniques and ApplicationsAdvanced MRI Techniques and ApplicationsMultiple Sclerosis Research Studies

Magnetic Resonance Imaging of Myelin

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Laule, Cornelia, Vavasour, Irene M., Kolind, Shannon H., Li, David K.B., Traboulsee, Tony L., Moore, G.R. Wayne, MacKay, Alex L.·2007·Neurotherapeutics

DOI 10.1016/j.nurt.2007.05.004PMC PMC7479725

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Abstract

The ability to measure myelin in vivo has great consequences for furthering our knowledge of normal development, as well as for understanding a wide range of neurological disorders. The following review summarizes the current state of myelin imaging using MR. We consider five MR techniques that have been used to study myelin: 1) conventional MR, 2) MR spectroscopy, 3) diffusion, 4) magnetization transfer, and 5) T2 relaxation. Fundamental studies involving peripheral nerve and MR/histology comparisons have aided in the interpretation and validation of MR data. We highlight a number of important findings related to myelin development, damage, and repair, and we conclude with a critical summary of the current techniques available and their potential to image myelin in vivo.

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A relatively abundant MAG level might indicate a relatively intact myelin-axon interface in the CD1 mice, albeit a damaged outer myelin sheath.
“a relatively abundant MAG level might indicate a relatively intact myelin-axon interface in the CD1 mice, albeit a damaged outer myelin sheath.”
From Strain differences in cuprizone induced demyelination (2017) · cites this paper as [37]
Section 4 describes a possible role for MAG in interactions between oligodendrocytes and axons, which lends limited support to the proposed interpretation. It does not report MAG levels in CD1 mice or establish that abundant MAG indicates an intact myelin–axon interface despite damage to the outer sheath. No page number is available in our copy. (LLM, conf=0.78)
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Solving Least Squares Problems
Lawson, C. L., & Hanson, R. J. (1995) · doi:10.1137/1.9781611971217 · Cited by 7,103 · see citing works
The basis of anisotropic water diffusion in the nervous system—A technical review.
Beaulieu, C. (2002) · NMR in Biomedicine · doi:10.1002/nbm.782 · Cited by 4,653 · see citing works
Axonal transection in the lesions of multiple sclerosis
Trapp, B. D., Peterson, J., Ransohoff, R. M., Rudick, R., Mörk, S., & Bö, L. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801293380502 · Cited by 4,029 · see citing works
Solving Least Squares Problems.
Ling, R. F., Lawson, C. L., & Hanson, R. J. (1977) · Journal of the American Statistical Association · doi:10.2307/2286501 · Cited by 2,757 · see citing works
Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water
Song, S.-K., Sun, S.-W., Ramsbottom, M. J., Chang, C., Russell, J., & Cross, A. H. (2002) · NeuroImage · doi:10.1006/nimg.2002.1267 · Cited by 2,582 · see citing works
Regional Development of the Brain in Early Life
(1968) · Archives of Disease in Childhood · doi:10.1136/adc.43.229.388 · Cited by 2,107 · see citing works
Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia
Song, S.-K., Sun, S.-W., Ju, W.-K., Lin, S.-J., Cross, A. H., & Neufeld, A. H. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.07.005 · Cited by 1,738 · see citing works
A Method for the Combined Staining of Cells and Fibers in the Nervous System
Klüver, H., & Barrera, E. (1953) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-195312040-00008 · Cited by 1,724 · see citing works
Demyelination increases radial diffusivity in corpus callosum of mouse brain
Song, S.-K., Yoshino, J., Le, T. Q., Lin, S.-J., Sun, S.-W., Cross, A. H., & Armstrong, R. C. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.028 · Cited by 1,658 · see citing works
Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo
Wolff, S. D., & Balaban, R. S. (1989) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910100113 · Cited by 1,482 · see citing works
From charcot to lou gehrig: deciphering selective motor neuron death in als
Cleveland, D. W., & Rothstein, J. D. (2001) · Nature reviews. Neuroscience · doi:10.1038/35097565 · Cited by 1,389 · see citing works
Basic Neurochemistry: Molecular, Cellular, and Medical Aspects
Siegel, G. J., & Agranoff, B. W. (1989) · Cited by 1,357 · see citing works
Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
Hakak, Y., Walker, J. R., Li, C., Wong, W. H., Davis, K. L., Buxbaum, J. D., Haroutunian, V., & Fienberg, A. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081071198 · Cited by 1,192 · see citing works
Basic Neurochemistry: Molecular, Cellular, and Medical Aspects
Davison, A. (1989) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.8.1021-a · Cited by 949 · see citing works
Magnetization transfer in MRI: a review
Henkelman, R. M., Stanisz, G. J., & Graham, S. J. (2001) · NMR in Biomedicine · doi:10.1002/nbm.683 · Cited by 922 · see citing works
In vivo visualization of myelin water in brain by magnetic resonance
MacKay, A. L., Whittall, K. P., Adler, J., Li, D. K. B., Paty, D. W., & Graeb, D. A. (1994) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910310614 · Cited by 916 · see citing works
Self-citation
Sequence of Central Nervous System Myelination in Human Infancy. II. Patterns of Myelination in Autopsied Infants
Kinney, H. C., Ann brody, B., Kloman, A. S., & Gilles, F. H. (1988) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-198805000-00003 · Cited by 888 · see citing works
Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
Filbin, M. T. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1195 · Cited by 873 · see citing works
In vivo measurement of T 2 distributions and water contents in normal human brain
Whittall, K. P., MacKay, A. L., Graeb, D. A., Nugent, R. A., Li, D. K. B., & Paty, D. W. (1997) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910370107 · Cited by 796 · see citing works
Self-citation
Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain
Schmierer, K., Scaravilli, F., Altmann, D. R., Barker, G. J., & Miller, D. H. (2004) · Annals of Neurology · doi:10.1002/ana.20202 · Cited by 777 · see citing works
Normal maturation of the neonatal and infant brain: MR imaging at 1.5 T.
Barkovich, A. J., Kjos, B. O., Jackson, D. E., & Norman, D. M. (1988) · Radiology · doi:10.1148/radiology.166.1.3336675 · Cited by 741 · see citing works
Microstructural Development of Human Newborn Cerebral White Matter Assessed in Vivo by Diffusion Tensor Magnetic Resonance Imaging
Hüppi, P. S., Maier, S. E., Peled, S., Zientara, G. P., Barnes, P. D., Jolesz, F. A., & Volpe, J. J. (1998) · Pediatric Research · doi:10.1203/00006450-199810000-00019 · Cited by 722 · see citing works
Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging.
Dousset, V., Grossman, R. I., Ramer, K., Schnall, M. D., YOUNG, L. H. Y., González‐Scarano, F., Lavi, E., & Cohen, J. A. (1992) · Radiology · doi:10.1148/radiology.182.2.1732968 · Cited by 689 · see citing works
Development of the human brain: In vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy
Kreis, R., Ernst, T., & Ross, B. D. (1993) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910300405 · Cited by 680 · see citing works
Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis
van Walderveen, M. A. A., Kamphorst, W., Scheltens, P., van Waesberghe, J. H. T. M., Ravid, R., Valk, J., Polman, C. H., & Barkhof, F. (1998) · Neurology · doi:10.1212/wnl.50.5.1282 · Cited by 656 · see citing works
Diffusion tensor imaging and aging
Sullivan, E. V., & Pfefferbaum, A. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.06.002 · Cited by 649 · see citing works
Quantitative interpretation of NMR relaxation data
Whittall, K. P., & MacKay, A. L. (1989) · Journal of Magnetic Resonance (1969) · doi:10.1016/0022-2364(89)90011-5 · Cited by 633 · see citing works
Self-citation
In vivo imaging of axonal degeneration and regeneration in the injured spinal cord
Kerschensteiner, M., Schwab, M. E., Lichtman, J. W., & Misgeld, T. (2005) · Nature Medicine · doi:10.1038/nm1229 · Cited by 582 · see citing works
White matter damage in Alzheimer’s disease assessed in vivo using diffusion tensor magnetic resonance imaging
Bozzali, M. (2002) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.6.742 · Cited by 568 · see citing works
Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology
Brück, W., Bitsch, A., Kolenda, H., Brück, Y., Stiefel, M., & Lassmann, H. (1997) · Annals of Neurology · doi:10.1002/ana.410420515 · Cited by 520 · see citing works
Electron microscopy of oligodendroglia in severe mental illness
Uranova, N., Orlovskaya, D., Vikhreva, O., Zimina, I., Kolomeets, N., Vostrikov, V., & Rachmanova, V. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00528-7 · Cited by 495 · see citing works
White matter changes in mild cognitive impairment and AD: a diffusion tensor imaging study
Medina, D., deToledo-Morrell, L., Urresta, F., Gabrieli, J. D. E., Moseley, M., Fleischman, D., Bennett, D. A., Leurgans, S., Turner, D. A., & Stebbins, G. T. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.03.026 · Cited by 492 · see citing works
Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology
Laule, C., Leung, E., Li, D. K., Traboulsee, A. L., Paty, D. W., MacKay, A. L., & Moore, G. R. (2006) · Multiple Sclerosis Journal · doi:10.1177/1352458506070928 · Cited by 489 · see citing works
Self-citation
Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences
Bjartmar, C., & Trapp, B. D. (2001) · Current Opinion in Neurology · doi:10.1097/00019052-200106000-00003 · Cited by 479 · see citing works
Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum
Sun, S., Liang, H., Trinkaus, K., Cross, A. H., Armstrong, R. C., & Song, S. (2006) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20774 · Cited by 461 · see citing works
Concepts of myelin and myelination in neuroradiology.
Barkovich, A. J. (2000) · PubMed Central · Cited by 460 · see citing works
Myelination and organization of the frontal white matter in children
Klingberg, T., Vaidya, C. J., Gabrieli, J. D. E., Moseley, M. E., & Hedehus, M. (1999) · Neuroreport · doi:10.1097/00001756-199909090-00022 · Cited by 458 · see citing works
Compromised White Matter Tract Integrity in Schizophrenia Inferred From Diffusion Tensor Imaging
Lim, K. O., Hedehus, M., Moseley, M. E., de Crespigny, A. J., Sullivan, E. V., & Pfefferbaum, A. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.4.367 · Cited by 447 · see citing works
Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins
Flynn, S. W., Lang, D. J., MacKay, A. L., Goghari, V. M., Vavasour, I. M., Whittall, K. P., Smith, G. N., Arango, V., Mann, J. J., Dwork, A. J., et al. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001337 · Cited by 439 · see citing works
Self-citation
DTI and MTR abnormalities in schizophrenia: Analysis of white matter integrity
Kubicki, M. R., Park, H., Westin, C., Nestor, P. G., Mulkern, R. V., Maier, S. E., Niznikiewicz, M. A., Connor, E. E., Levitt, J. J., Frumin, M., et al. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.026 · Cited by 433 · see citing works
Water diffusion compartmentation and anisotropy at high b values in the human brain
Clark, C. A., & Bihan, D. L. (2000) · Magnetic Resonance in Medicine · doi:10.1002/1522-2594(200012)44:6 · Cited by 424 · see citing works
Self-citation
Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis
Evangelou, N. (2000) · Brain · doi:10.1093/brain/123.9.1845 · Cited by 416 · see citing works
White Matter Structural Integrity in Healthy Aging Adults and Patients With Alzheimer Disease
Bartzokis, G., Cummings, J. L., Sultzer, D. L., Henderson, V. W., Nuechterlein, K. H., & Mintz, J. (2003) · Archives of Neurology · doi:10.1001/archneur.60.3.393 · Cited by 415 · see citing works
Practical T2 quantitation for clinical applications
Poon, C. S., & Henkelman, R. M. (1992) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1880020512 · Cited by 396 · see citing works
Diffusion tensor imaging of post mortem multiple sclerosis brain
Schmierer, K., Wheeler-Kingshott, C. A. M., Boulby, P. A., Scaravilli, F., Altmann, D. R., Barker, G. J., Tofts, P. S., & Miller, D. H. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.12.010 · Cited by 395 · see citing works
Magnetization transfer changes in the normal appering white matter precede the appearance of enhancing lesions in patients with multiple sclerosis
Filippi, M., Rocca, M. A., Martino, G., Horsfield, M. A., & Comi, G. (1998) · Annals of Neurology · doi:10.1002/ana.410430616 · Cited by 395 · see citing works
Water content and myelin water fraction in multiple sclerosis
Laule, C., Vavasour, I. M., Moore, G. R. W., Oger, J. J.-F., Li, D. K. B., Paty, D. W., & MacKay, A. L. (2004) · Journal of Neurology · doi:10.1007/s00415-004-0306-6 · Cited by 369 · see citing works
Self-citation
Cajal's Degeneration and Regeneration of the Nervous System
y Cajal, S. R., & May, R. M. (1991) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195065169.001.0001 · Cited by 367 · see citing works
A Magnetization Transfer Imaging Study of Normal-Appearing White Matter in Multiple Sclerosis
Filippi, M., Campi, A., Dousset, V., Baratti, C., Martinelli, V., Canal, N., Scotti, G., & Comi, G. (1995) · Neurology · doi:10.1212/wnl.45.3.478 · Cited by 366 · see citing works
Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical “disconnection” in aging and Alzheimer's disease.
Bartzokis, G., Sultzer, D., Lu, P. H., Nuechterlein, K. H., Mintz, J., & Cummings, J. L. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.09.005 · Cited by 363 · see citing works
Remyelinated Lesions in Multiple Sclerosis
Barkhof, F., Brück, W., Groot, C. J. A. D., Bergers, E., Hulshof, S. C. J., Geurts, J. J. G., Polman, C. H., & van der Valk, P. (2003) · Archives of Neurology · doi:10.1001/archneur.60.8.1073 · Cited by 328 · see citing works
Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia
Edgar, J. M., McLaughlin, M., Yool, D., Zhang, S.-C., Fowler, J. H., Montague, P., Barrie, J. A., McCulloch, M. C., Duncan, I. D., Garbern, J., et al. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200312012 · Cited by 328 · see citing works
Multiple Sclerosis
Keegan, B. M., & Noseworthy, J. H. (2002) · Annual Review of Medicine · doi:10.1146/annurev.med.53.082901.103909 · Cited by 317 · see citing works
Neuropathological abnormalities of the corpus callosum in schizophrenia: a diffusion tensor imaging study
Foong, J. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.68.2.242 · Cited by 316 · see citing works
Serial proton magnetic resonance spectroscopic imaging, contrast‐enhanced magnetic resonance imaging, and quantitative lesion volumetry in multiple sclerosis
Narayana, P. A., Doyle, T. J., Lai, D., & Wolinsky, J. S. (1998) · Annals of Neurology · doi:10.1002/ana.410430112 · Cited by 316 · see citing works
Myelin Biology and Disorders
Lazzarini, R. A., Griffin, J. W., Lassman, H., Nave, K., Miller, R. H., & Trapp, B. D. (2004) · Elsevier eBooks · doi:10.1016/b978-0-12-439510-7.x5051-7 · Cited by 313 · see citing works
Iron in Chronic Brain Disorders: Imaging and Neurotherapeutic Implications
Stankiewicz, J. M., Panter, S. S., Neema, M., Arora, A., Batt, C. E., & Bakshi, R. (2007) · Neurotherapeutics · doi:10.1016/j.nurt.2007.05.006 · Cited by 301 · see citing works
Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference
Barker, P. B., Soher, B. J., Blackband, S. J., Chatham, J. C., Mathews, V. P., & Bryan, R. N. (1993) · NMR in Biomedicine · doi:10.1002/nbm.1940060114 · Cited by 299 · see citing works
High field MRI correlates of myelin content and axonal density in multiple sclerosis
Mottershead, J. P., Schmierer, K., Clemence, M., Thornton, J. S., Scaravilli, F., Barker, G. J., Tofts, P. S., Newcombe, J., Cuzner, M. L., Ordidge, R. J., et al. (2003) · Journal of Neurology · doi:10.1007/s00415-003-0192-3 · Cited by 296 · see citing works
Age‐Related Changes in Prefrontal White Matter Measured by Diffusion Tensor Imaging
SALAT, D. H., TUCH, D. S., HEVELONE, N. D., FISCHL, B., CORKIN, S., ROSAS, H. D., & DALE, A. M. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1340.009 · Cited by 292 · see citing works
Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis
Cercignani, M. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.70.3.311 · Cited by 287 · see citing works
Brain dysmyelination and recovery assessment by noninvasive in vivo diffusion tensor magnetic resonance imaging
Harsan, L. A., Poulet, P., Guignard, B., Steibel, J., Parizel, N., de Sousa, P. L., Boehm, N., Grucker, D., & Ghandour, M. S. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20742 · Cited by 284 · see citing works
Relaxivity and magnetization transfer of white matter lipids at MR imaging: importance of cerebrosides and pH.
Kucharczyk, W., Macdonald, P. M., Stanisz, G. J., & Henkelman, R. M. (1994) · Radiology · doi:10.1148/radiology.192.2.8029426 · Cited by 273 · see citing works
1 H MR spectroscopy in common dementias
Kantarci, K., Petersen, R. C., Boeve, B. F., Knopman, D. S., Tang‐Wai, D. F., O’Brien, P. C., Weigand, S. D., Edland, S. D., Smith, G. E., Ivnik, R. J., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000141849.21256.ac · Cited by 263 · see citing works
Color-coded diffusion-tensor-imaging of posterior cingulate fiber tracts in mild cognitive impairment
Fellgiebel, A., Müller, M. J., Wille, P. R., Dellani, P. R., Scheurich, A., Schmidt, L., & Stoeter, P. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.11.006 · Cited by 261 · see citing works
Characterizing white matter with magnetization transfer andT2
Stanisz, G. J., Kecojević, A., Bronskill, M. J., & Henkelman, R. M. (1999) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(199912)42:6 · Cited by 249 · see citing works
Immunocytochemical observations on the distribution of myelin‐associated glycoprotein and myelin basic protein in multiple sclerosis lesions
Itoyama, Y., Sterhberger, N. H., Webster, H. D., Quarles, R. H., Cohen, S. R., & Richardson, E. P. (1980) · Annals of Neurology · doi:10.1002/ana.410070212 · Cited by 241 · see citing works
Defining and Categorizing Leukoencephalopathies of Unknown Origin: MR Imaging Approach
van der Knaap, M. S., Breiter, S. N., Naidu, S., Hart, A. A. M., & Valk, J. (1999) · Radiology · doi:10.1148/radiology.213.1.r99se01121 · Cited by 240 · see citing works
Detecting axon damage in spinal cord from a mouse model of multiple sclerosis
Kim, J. H., Budde, M. D., Liang, H.-F., Klein, R. S., Russell, J. H., Cross, A. H., & Song, S.-K. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.09.009 · Cited by 235 · see citing works
Relative indices of water diffusion anisotropy are equivalent in live and formalin-fixed mouse brains
Sun, S., Neil, J. J., & Song, S. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10605 · Cited by 231 · see citing works
Abnormal brain white matter in schizophrenia: a diffusion tensor imaging study
Agartz, I., Andersson, J., & Skare, S. T. (2001) · Neuroreport · doi:10.1097/00001756-200107200-00041 · Cited by 225 · see citing works
White matter development during late adolescence in healthy males: A cross-sectional diffusion tensor imaging study
Ashtari, M., Cervellione, K. L., Hasan, K. M., Wu, J., McIlree, C., Kester, H. M., Ardekani, B. A., Roofeh, D., Szeszko, P. R., & Kumra, S. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.10.047 · Cited by 221 · see citing works
Differential sensitivity of in vivo and ex vivo diffusion tensor imaging to evolving optic nerve injury in mice with retinal ischemia
Sun, S., Liang, H., Le, T. Q., Armstrong, R. C., Cross, A. H., & Song, S. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.04.212 · Cited by 218 · see citing works
Diffusion tensor imaging in early Alzheimer's disease.
Naggara, O., Oppenheim, C., Rieu, D., Raoux, N., Rodrigo, S., Barba, G. D., & Meder, J. (2006) · Psychiatry Research · doi:10.1016/j.pscychresns.2006.01.005 · Cited by 218 · see citing works
A serial study of new MS lesions and the white matter from which they arise
Goodkin, D. E., Rooney, W., Sloan, R., Bacchetti, P., Gee, L., Vermathen, M., Waubant, E., Abundo, M., Majumdar, S., Nelson, S., et al. (1998) · Neurology · doi:10.1212/wnl.51.6.1689 · Cited by 217 · see citing works
A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesions
Bitsch, A., Kuhlmann, T., Stadelmann, C., Lassmann, H., Lucchinetti, C. F., & Brück, W. (2001) · Annals of Neurology · doi:10.1002/ana.1053 · Cited by 216 · see citing works
Neuropathology of white matter changes in Alzheimer’s disease and vascular dementia
Englund, E. (1998) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000051183 · Cited by 213 · see citing works
Age-related degeneration of corpus callosum measured with diffusion tensor imaging
Ota, M., Obata, T., Akine, Y., Ito, H., Ikehira, H., Asada, T., & Suhara, T. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.02.008 · Cited by 210 · see citing works
Wallerian degeneration after cerebral infarction: evaluation with sequential MR imaging.
Kuhn, M. J., Mikulis, D. J., Ayoub, D. M., Kosofsky, B. E., Davis, K. R., & Taveras, J. M. (1989) · Radiology · doi:10.1148/radiology.172.1.2740501 · Cited by 204 · see citing works
Remyelination in multiple sclerosis
Brück, W., Kuhlmann, T., & Stadelmann, C. (2003) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00191-0 · Cited by 202 · see citing works
Pathologic damage in MS assessed by diffusion-weighted and magnetization transfer MRI
Cercignani, M., Iannucci, G., Rocca, M. A., Comı, G., Horsfield, M. A., & Filippi, M. (2000) · Neurology · doi:10.1212/wnl.54.5.1139 · Cited by 185 · see citing works
Use of magnetic resonance imaging for in vivo measurements of water content in human brain: method and normal values
Fatouros, P. P., & Marmarou, A. (1999) · Journal of neurosurgery · doi:10.3171/jns.1999.90.1.0109 · Cited by 185 · see citing works
Increased water self-diffusion in chronic plaques and in apparently normal white matter in patients with multiple sclerosis
Christiansen, P., Gideon, P., Thomsen, C., Stubgaard, M., Henriksen, O. M., & Larsson, H. B. W. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1993.tb04100.x · Cited by 185 · see citing works
A pathology–MRI study of the short-T2 component in formalin-fixed multiple sclerosis brain
Moore, G. R. W., Leung, E., MacKay, A. L., Vavasour, I. M., Whittall, K. P., Cover, K. S., Li, D. K. B., Hashimoto, S. A., Oger, J., Sprinkle, T. J., et al. (2000) · Neurology · doi:10.1212/wnl.55.10.1506 · Cited by 185 · see citing works
Self-citation
Gradual loss of myelin and formation of an astrocytic scar during Wallerian degeneration in the human spinal cord
Buss, A. (2003) · Brain · doi:10.1093/brain/awh001 · Cited by 183 · see citing works
Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging
Schuff, N. W., Ezekiel, F., Gamst, A. C., Amend, D. L., Capizzano, A. A., Maudsley, A. A., & Weiner, M. W. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1119 · Cited by 183 · see citing works
In vivo magnetic resonance diffusion measurement in the brain of patients with multiple sclerosis
Larsson, H. B. W., Thomsen, C., Frederiksen, J., Stubgaard, M., & Henriksen, O. (1992) · Magnetic Resonance Imaging · doi:10.1016/0730-725x(92)90367-9 · Cited by 181 · see citing works
Criteria for analysis of multicomponent tissue T2 relaxation data
Graham, S. J., Stanchev, P. L., & Bronskill, M. J. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910350315 · Cited by 179 · see citing works
Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI
Bozzali, M., Franceschi, M., Falini, A., Pontesilli, S., Cercignani, M., Magnani, G., Scotti, G., Comi, G., & Filippi, M. (2001) · Neurology · doi:10.1212/wnl.57.6.1135 · Cited by 179 · see citing works
Remyelination of CNS axons by Schwann cells transplanted from the sciatic nerve
Blakemore, W. F. (1977) · Nature · doi:10.1038/266068a0 · Cited by 178 · see citing works
Changes in brain water diffusion during childhood
Morriss, M. C., Zimmerman, R. A., Bilaniuk, L. T., Hunter, J. V., & Haselgrove, J. C. (1999) · Neuroradiology · doi:10.1007/s002340050869 · Cited by 174 · see citing works
Is multicomponent T2 a good measure of myelin content in peripheral nerve?
Webb, S., Munro, C. A., Midha, R., & Stanisz, G. J. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10411 · Cited by 172 · see citing works
Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis.
Bö, L., Geurts, J., van der Valk, P., Polman, C., & Barkhof, F. (2007) · Archives of Neurology · doi:10.1001/archneur.64.1.76 · Cited by 172 · see citing works
MRI characterization of diffusion coefficients in a rat spinal cord injury model
Ford, J. C., Hackney, D. B., Alsop, D. C., Jara, H. J., Joseph, P. M., Hand, C. M., & Black, P. (1994) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910310504 · Cited by 170 · see citing works
Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination
Tsunoda, I., & Fujinami, R. S. (2002) · Springer Seminars in Immunopathology · doi:10.1007/s00281-002-0105-z · Cited by 164 · see citing works
Lysolecithin-induced demyelination in primates: preliminary in vivo study with MR and magnetization transfer.
Dousset, V., Brochet, B., Vital, A., Gross, C. E., Benazzouz, A., Boullerne, A. I., Bidabé, A. M., Gin, A.-M., & Caillé, J. (1995) · PubMed Central · Cited by 162 · see citing works
Neuropathology of Phenylketonuria
Malamud, N. (1966) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-196604000-00006 · Cited by 155 · see citing works
Magnetization transfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhanced spin-echo images and nonenhanced T1-weighted images.
Hiehle, J. F., Grossman, R. I., Ramer, K., González‐Scarano, F., & Cohen, J. A. (1995) · PubMed Central · Cited by 154 · see citing works
Diffusion Tensor Imaging of Frontal White Matter Microstructure in Early Alzheimer’s Disease: A Preliminary Study
Choi, S. J., Lim, K. O., Monteiro, I. M., & Reisberg, ‌. (2005) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988704271763 · Cited by 153 · see citing works
In vivo evaluation of remyelination in rat brain by magnetization transfer imaging
Deloire-Grassin, M., Brochet, B., Quesson, B., Delalande, C., Dousset, V., Canioni, P., & Petry, K. G. (2000) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00331-2 · Cited by 150 · see citing works
Diffusion imaging of the spinal cord in vivo: Estimation of the principal diffusivities and application to multiple sclerosis
Clark, C. A., Werring, D. J., & Miller, D. H. (2000) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(200001)43:1 · Cited by 150 · see citing works
Choline is increased in pre-lesional normal appearing white matter in multiple sclerosis
Tartaglia, M. C., Narayanan, S., Stefano, N. D., Arnaoutelis, R., Antel, S. B., Francis, S. J., dos Santos, A. C., Lapierre, Y., & Arnold, D. L. (2002) · Journal of Neurology · doi:10.1007/s00415-002-0846-6 · Cited by 149 · see citing works
Measurement of in vivo multi-component T2 relaxation times for brain tissue using multi-slice T2 prep at 1.5 and 3 T
Oh, J., Han, E. T., Pelletier, D., & Nelson, S. J. (2005) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2005.10.016 · Cited by 148 · see citing works
The Spinal Cord in Multiple Sclerosis: Relationship of High-Spatial-Resolution Quantitative MR Imaging Findings to Histopathologic Results
Bot, J., Blezer, E. L. A., Kamphorst, W., Nijeholt, G. J. L. À., Adèr, H. J., Castelijns, J. A., Nicolay, K., Bergers, E., Ravid, R., Polman, C. H., et al. (2004) · Radiology · doi:10.1148/radiol.2332031572 · Cited by 147 · see citing works
Axonal damage in the spinal cord of MS patients occurs largely independent of T2 MRI lesions
Bergers, E., Bot, J., Groot, C. J. A. D., Polman, C. H., Nijeholt, G. J. L. À., Castelijns, J. A., van der Valk, P., & Barkhof, F. (2002) · Neurology · doi:10.1212/01.wnl.0000036566.00866.26 · Cited by 146 · see citing works
A Proton Magnetic Resonance Spectroscopy Study of Age-related Changes in Frontal Lobe Metabolite Concentrations
Brooks, J. C. W., Roberts, N., Kemp, G. J., Gosney, M., Lye, M., & Whitehouse, G. H. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.7.598 · Cited by 146 · see citing works
Proton magnetic resonance spectroscopy in multiple sclerosis
Wolinsky, J. S., Narayana, P. A., & Fenstermacher, M. J. (1990) · Neurology · doi:10.1212/wnl.40.11.1764 · Cited by 145 · see citing works
MR spectroscopic evidence for glial increase but not for neuro‐axonal damage in MS normal‐appearing white matter
Vrenken, H., Barkhof, F., Uitdehaag, B. M. J., Castelijns, J. A., Polman, C. H., & Pouwels, P. J. W. (2005) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20366 · Cited by 144 · see citing works
A Wallerian degeneration pattern in patients at risk for MS
Simon, J. H., Kinkel, R. P., Jacobs, L., Bub, L., & Simonian, N. A. (2000) · Neurology · doi:10.1212/wnl.54.5.1155 · Cited by 142 · see citing works
Morphologic and histoanatomic observations of the brain in untreated human phenylketonuria
Bauman, M. L., & Kemper, T. (1982) · Acta Neuropathologica · doi:10.1007/bf00692698 · Cited by 141 · see citing works
Magnetic resonance techniques in the assessment of myelin and myelination
Barkovich, A. J. (2005) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-005-5952-z · Cited by 140 · see citing works
Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease
van der Flier, W. M., van den Heuvel, D. M. J., Weverling‐Rijnsburger, A. W. E., Bollen, E. L. E. M., Westendorp, R. G. J., van Buchem, M. A., & Middelkoop, H. A. M. (2002) · Annals of Neurology · doi:10.1002/ana.10244 · Cited by 139 · see citing works
MR properties of excised neural tissue following experimentally induced inflammation
Stanisz, G. J., Webb, S., Munro, C. A., Pun, T., & Midha, R. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20008 · Cited by 138 · see citing works
MR properties of excised neural tissue following experimentally induced demyelination
Odrobina, E., Lam, T. Y. J., Pun, T., Midha, R., & Stanisz, G. (2005) · NMR in Biomedicine · doi:10.1002/nbm.951 · Cited by 138 · see citing works
Comparison of the pathology of cerebral white matter with post‐mortem magnetic resonance imaging (MRI) in the elderly brain
Fernando, M. S., O'Brien, J. T., Perry, R. H., English, P. T., Forster, G., McMeekin, W., Slade, J. Y., Golkhar, A., Matthews, F. E., Barber, R., et al. (2004) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2004.00550.x · Cited by 137 · see citing works
Age-related Changes in Conventional, Magnetization Transfer, and Diffusion-Tensor MR Imaging Findings: Study with Whole-Brain Tissue Histogram Analysis1
Rovaris, M., Iannucci, G., Cercignani, M., Sormani, M. P., Stefano, N. D., Gerevini, S., Comi, G., & Filippi, M. (2003) · Radiology · doi:10.1148/radiol.2273020721 · Cited by 137 · see citing works
A Comprehensive Review of Proton Magnetic Resonance Spectroscopy Studies in Dementia and Parkinson’s Disease
Firbank, M. J., Harrison, R. M., & O'Brien, J. T. (2002) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000064927 · Cited by 131 · see citing works
CHEMISTRY OF WALLERIAN DEGENERATION
Johnson, A. C. (1950) · Archives of Neurology And Psychiatry · doi:10.1001/archneurpsyc.1950.02310250111010 · Cited by 130 · see citing works
In vivo determination of T1 and T2 in the brain of patients with severe but stable multiple sclerosis
Larsson, H. B. W., Frederiksen, J. L., Kjær, L., Henriksen, O. M., & Olesen, J. (1988) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910070106 · Cited by 129 · see citing works
Fine-structural changes of myelin sheaths after axonal degeneration in the spinal cord of rats.
Lampert, P. W., & Cressman, M. R. (1966) · PubMed · Cited by 128 · see citing works
Spin‐spin relaxation in experimental allergic Encephalomyelitis. Analysis of CPMG data using a non‐linear least squares method and linear inverse theory
Stewart, W. A., MacKay, A. L., Whittall, K. P., Moore, G. R. W., & Paty, D. W. (1993) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910290608 · Cited by 128 · see citing works
Self-citation
Superparamagnetic Iron Oxide-Labeled Schwann Cells and Olfactory Ensheathing Cells Can Be TracedIn Vivoby Magnetic Resonance Imaging and Retain Functional Properties after Transplantation into the CNS
Dunning, M., Lakatos, A., Loizou, L., Kettunen, M. I., ffrench‐Constant, C., Brindle, K. M., & Franklin, R. J. M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3126-04.2004 · Cited by 126 · see citing works
Diffusion tensor imaging in multiple sclerosis: assessment of regional differences in the axial plane within normal-appearing cervical spinal cord.
(2006) · PubMed Central · Cited by 126 · see citing works
Diffusional anisotropy of T2 components in bovine optic nerve
Stanisz, G. J., & Henkelman, R. M. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910400310 · Cited by 121 · see citing works
Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging
Sun, S.-W., Song, S.-K., Harms, M. P., Lin, S.-J., Holtzman, D. M., Merchant, K. M., & Kotyk, J. J. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2004.09.006 · Cited by 121 · see citing works
Nuclear magnetic resonance relaxation in experimental brain edema: Effects of water concentration, protein concentration, and temperature
Kamman, R. L., Go, K. G., Brouwer, W., & Berendsen, H. J. C. (1988) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910060304 · Cited by 117 · see citing works
Visualization of nonstructural changes in early white matter development on diffusion-weighted MR images: evidence supporting premyelination anisotropy.
Prayer, D., Barkovich, A. J., Kirschner, D. A., Prayer, L., Roberts, T. P. L., Kucharczyk, J. R., & Moseley, M. E. (2001) · PubMed Central · Cited by 117 · see citing works
Diffusion-weighted MR imaging in leukodystrophies
Patay, Z. J. (2005) · European Radiology · doi:10.1007/s00330-005-2846-2 · Cited by 114 · see citing works
Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging study
Bartzokis, G., Nuechterlein, K. H., Lu, P., Gitlin, M. J., Rogers, S., & Mintz, J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01835-8 · Cited by 114 · see citing works
A comparison between magnetization transfer ratios and myelin water percentages in normals and multiple sclerosis patients
Vavasour, I. M., Whittall, K. P., MacKay, A. L., Li, D. K. B., Vorobeychik, G., & Paty, D. W. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910400518 · Cited by 111 · see citing works
Self-citation
Gray and White Matter Brain Abnormalities in First-Episode Schizophrenia Inferred From Magnetization Transfer Imaging
Bagary, M. S., Symms, M. R., Barker, G. J., Mutsatsa, S., Joyce, E. M., & Ron, M. A. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.8.779 · Cited by 110 · see citing works
Magnetization transfer and diffusion tensor MR imaging of acute disseminated encephalomyelitis.
Inglese, M., Salvi, F., Iannucci, G., Mancardi, G., Mascalchi, M., & Filippi, M. (2002) · PubMed Central · Cited by 110 · see citing works
Multi-component apparent diffusion coefficients in human brain: Relationship to spin-lattice relaxation
Mulkern, R. V., Zengingönül, H. P., Robertson, R. L., Bogner, P., Zou, K. H., Guðbjartsson, H., Guttmann, C. R. G., Holtzman, D. H., Kyriakos, W. E., Jolesz, F. A., et al. (2000) · Magnetic Resonance in Medicine · doi:10.1002/1522-2594(200008)44:2 · Cited by 109 · see citing works
MRI of the brain with ultra-short echo-time pulse sequences
Waldman, A. D., Rees, J. H., Brock, C., Robson, M. D., Gatehouse, P. D., & Bydder, G. M. (2003) · Neuroradiology · doi:10.1007/s00234-003-1076-z · Cited by 109 · see citing works
MR diffusion tensor imaging and fiber tracking in inflammatory diseases of the spinal cord.
Renoux, J., Facon, D., Fillard, P., Huynh‐Charlier, I., Lasjaunias, P. L., & Ducreux, D. (2006) · PubMed Central · Cited by 109 · see citing works
Diffusion-weighted and magnetization transfer imaging of the corpus callosum in Alzheimer’s disease
Hanyu, H., Asano, T., Sakurai, H., Imon, Y., Iwamoto, T., Takasaki, M., Shindo, H., & Abe, K. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(99)00135-5 · Cited by 108 · see citing works
Magnetization transfer MR of the normal adult brain.
Mehta, R. C., Pike, G. B., & Enzmann, D. R. (1996) · PubMed · Cited by 108 · see citing works
Early structural changes in acute MS lesions assessed by serial magnetization transfer studies
Dousset, V., Gayou, A., Brochet, B., & Caillé, J. (1998) · Neurology · doi:10.1212/wnl.51.4.1150 · Cited by 108 · see citing works
Serial magnetization transfer imaging to characterize the early evolution of new MS lesions
Silver, N., Lai, M., Symms, M. R., Barker, G. J., McDonald, W. I., & Miller, D. H. (1998) · Neurology · doi:10.1212/wnl.51.3.758 · Cited by 107 · see citing works
Diffraction Studies of Molecular Organization and Membrane Interactions in Myelin
Kirschner, D. A., Ganser, A. L., & Caspar, D. L. D. (1984) · Springer eBooks · doi:10.1007/978-1-4757-1830-0_2 · Cited by 106 · see citing works
Changes in Microtubule Stability and Density in Myelin-Deficient Shiverer Mouse CNS Axons
Kirkpatrick, L., Witt, A. S., Payne, H. R., Shine, H. D., & Brady, S. T. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-07-02288.2001 · Cited by 105 · see citing works
In vivo investigation of white matter pathology in schizophrenia with magnetisation transfer imaging
Foong, J. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.68.1.70 · Cited by 104 · see citing works
Magnetization Transfer Ratio in Mild Cognitive Impairment and Dementia of Alzheimer's Type
Kabani, N. J., Sled, J. G., & Chertkow, H. M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0992 · Cited by 103 · see citing works
Magnetisation transfer ratio of normal brain white matter: a normative database spanning four decades of life.
Silver, N., Barker, G. J., MacManus, D. G., Tofts, P. S., & Miller, D. H. (1997) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.62.3.223 · Cited by 103 · see citing works
Long-term changes of magnetization transfer-derived measures from patients with relapsing-remitting and secondary progressive multiple sclerosis.
Rocca, M. A., Mastronardo, G., Rodegher, M., Comi, G., & Filippi, M. (1999) · PubMed Central · Cited by 102 · see citing works
Age-dependent changes in magnetization transfer contrast of white matter in the pediatric brain.
Engelbrecht, V., Rassek, M., Preiss, S., Wald, C., & Mödder, U. (1998) · PubMed Central · Cited by 102 · see citing works
Multicontrast MRI of remyelination in the central nervous system
Merkler, D., Boretius, S., Stadelmann, C., Ernsting, T., Michaelis, T., Frahm, J., & Brück, W. (2005) · NMR in Biomedicine · doi:10.1002/nbm.972 · Cited by 102 · see citing works
Regional variations in normal brain shown by quantitative magnetization transfer imaging
Sled, J. G., Levesque, I. R., dos Santos, A. C., Francis, S. J., Narayanan, S., Brass, S. D., Arnold, D. L., & Pike, G. B. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10701 · Cited by 101 · see citing works
Further evidence for altered myelin biosynthesis and glutamatergic dysfunction in schizophrenia
Tkachev, D., Mimmack, M. L., Huffaker, S. J., Ryan, M., & Bahn, S. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145706007334 · Cited by 101 · see citing works
Localized 1H NMR spectroscopy in Canavan's Disease: A report of two cases
Austin, S. J., Connelly, A., Gadian, D. G., Benton, J. S., & Brett, E. M. (1991) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910190235 · Cited by 101 · see citing works
Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI
Agosta, F., Benedetti, B., Rocca, M. A., Valsasina, P., Rovaris, M., Comi, G., & Filippi, M. (2005) · Neurology · doi:10.1212/01.wnl.0000151852.15294.cb · Cited by 98 · see citing works
Lactate, N‐acetylaspartate, choline and creatine concentrations, and spin‐spin relaxation in thalamic and occipito‐parietal regions of developing human brain
Cady, E. B., Penrice, J., Amess, P., Lorek, A., Wylezinska, M., Aldridge, R. F., Franconi, F., Wyatt, J. S., & Reynolds, E. O. R. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910360610 · Cited by 97 · see citing works
The pathogenesis of the white matter abnormalities in phenylketonuria. A multimodal 3.0 tesla MRI and magnetic resonance spectroscopy (1H MRS) study
Leuzzi, V., Tosetti, M., Montanaro, D., Carducci, C., Artiola, C., Carducci, C., Antonozzi, I., Burroni, M., Carnevale, F. A., Chiarotti, F., et al. (2007) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-006-0399-4 · Cited by 97 · see citing works
Multiexponential T2 relaxation in degenerating peripheral nerve
Does, M. D., & Snyder, R. E. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910350212 · Cited by 95 · see citing works
Normal Brain Maturation Characterized With Age-Related T2 Relaxation Times: An Attempt to Develop a Quantitative Imaging Measure for Clinical Use
Ding, X. Q., Kucinski, T., Wittkugel, O., Goebell, E., Grzyska, U., Görg, M., Kohlschütter, A., & Zeumer, H. (2004) · Investigative Radiology · doi:10.1097/00004424-200412000-00005 · Cited by 95 · see citing works
Quantitative measurements with localized 1H MR spectroscopy in children with Canavan's disease
Wittsack, H., Kugel, H., Roth, B. J., & Heindel, W. L. (1996) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1880060609 · Cited by 94 · see citing works
Characterization of the NMR behavior of white matter in bovine brain
Bjarnason, T. A., Vavasour, I. M., Chia, C. L. L., & MacKay, A. L. (2005) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20680 · Cited by 94 · see citing works
Self-citation
Normal-appearing white matter in multiple sclerosis has heterogeneous, diffusely prolonged T2
Whittall, K. P., MacKay, A. L., Li, D. K. B., Vavasour, I. M., Jones, C. K., & Paty, D. W. (2002) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10076 · Cited by 92 · see citing works
Self-citation
Integrated data acquisition and processing to determine metabolite contents, relaxation times, and macromolecule baseline in single examinations of individual subjects
Kreis, R., Slotboom, J., Hofmann, L., & Boesch, C. (2005) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20673 · Cited by 91 · see citing works
Water compartments in the myelinated nerve. III. Pulsed NMR result
Vasilescu, V., Katona, É., Simplăceanu, V., & Demco, D. E. (1978) · Cellular and Molecular Life Sciences · doi:10.1007/bf01932339 · Cited by 90 · see citing works
Proton Relaxation Studies of Water Compartmentalization in a Model Neurological System
Menon, R. S., Rusinko, M. S., & Allen, P. S. (1992) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910280208 · Cited by 89 · see citing works
Diffusion tensor tractography-based group mapping of the pyramidal tract in relapsing-remitting multiple sclerosis patients.
Lin, F., Yu, C., Jiang, T., Li, K., & Chan, P. (2007) · PubMed Central · Cited by 88 · see citing works
Quantitative MR imaging R2 relaxometry in elderly participants reporting memory loss.
House, M. J., Pierre, T. G. S., Foster, J. K., Martins, R. N., & Clarnette, R. (2006) · PubMed Central · Cited by 87 · see citing works
Myelin in Multiple Sclerosis
Suzuki, K. (1973) · Archives of Neurology · doi:10.1001/archneur.1973.00490230029002 · Cited by 87 · see citing works
The myelinated axon is dependent on the myelinating cell for support and maintenance: Molecules involved
Edgar, J. M., & Garbern, J. Y. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20063 · Cited by 83 · see citing works
Multi-component T1 relaxation and magnetisation transfer in peripheral nerve
Does, M. D., Beaulieu, C., Allen, P. S., & Snyder, R. E. (1998) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(98)00139-8 · Cited by 83 · see citing works
Detection of myelin breakdown products by proton magnetic resonance spectroscopy
Davie, C. A., Barker, G. J., Tofts, P. S., Hawkins, C. P., Brennan, A., Miller, D. H., & McDonald, W. I. (1993) · The Lancet · doi:10.1016/0140-6736(93)90390-3 · Cited by 83 · see citing works
Diffusion Tensor Imaging in Multiple Sclerosis: Assessment of Regional Differences in the Axial Plane within Normal-Appearing Cervical Spinal Cord
Bowen, B. C. (2007) · Yearbook of Neurology and Neurosurgery · doi:10.1016/s0513-5117(08)70121-2 · Cited by 82 · see citing works
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease
Brockmann, K., Dechent, P., Wilken, B., Rusch, O., Frahm, J., & Hanefeld, F. A. (2003) · Neurology · doi:10.1212/01.wnl.0000049469.29011.e9 · Cited by 82 · see citing works
NEUROPATHOLOGIC OBSERVATIONS IN PHENYLKETONURIA
Poser, C. M., & van Bogaert, L. (1959) · Brain · doi:10.1093/brain/82.1.1-a · Cited by 82 · see citing works
A 1H magnetic resonance spectroscopy study of aging in parietal white matter: implications for trials in multiple sclerosis
Leary, S. M., Brex, P., MacManus, D. G., Parker, G. J. M., Barker, G. J., Miller, D. H., & Thompson, A. J. (2000) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(00)00131-4 · Cited by 81 · see citing works
Global estimation of myelination in the developing brain on the basis of magnetization transfer imaging: a preliminary study.
van Buchem, M. A., Steens, S. C. A., Vrooman, H. A., Zwinderman, A. H., McGowan, J. C., Rassek, M., & Engelbrecht, V. (2001) · PubMed Central · Cited by 79 · see citing works
Optimized spiral imaging for measurement of myocardial T2 relaxation
Foltz, W. D., Al-Kwifi, O. S., Sussman, M. S., Stainsby, J. A., & Wright, G. A. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10467 · Cited by 79 · see citing works
Quantifying Age-Related Myelin Breakdown with MRI: Novel Therapeutic Targets for Preventing Cognitive Decline and Alzheimer's Disease
Bartzokis, G., Lu, P. H., & Mintz, J. (2005) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6s604 · Cited by 78 · see citing works
Frontal lobe N-acetylaspartate correlates with psychopathology in schizophrenia: a proton magnetic resonance spectroscopy study
Sigmundsson, T., Maier, M., Toone, B., Williams, S., Simmons, A., Greenwood, K., & Ron, M. A. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00533-9 · Cited by 78 · see citing works
Magnetic resonance spectroscopy of multiple sclerosis: in-vivo detection of myelin breakdown products
Koopmans, R. A., Li, D. K. B., Zhu, G., Allen, P. S., Penn, A., & Paty, D. W. (1993) · The Lancet · doi:10.1016/0140-6736(93)90391-s · Cited by 78 · see citing works
Self-citation
Directional diffusion in relapsing‐remitting multiple sclerosis: A possible in vivo signature of Wallerian degeneration
Henry, R. G., Oh, J., Nelson, S. J., & Pelletier, D. (2003) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10379 · Cited by 77 · see citing works
MR spectroscopy of cervical spinal cord in patients with multiple sclerosis
Kendi, A. T. K., Tan, F. U., Kendi, M., Huvaj, S., & Tellioğlu, S. (2004) · Neuroradiology · doi:10.1007/s00234-004-1231-1 · Cited by 77 · see citing works
MR characteristics and neuropathology in adult-onset autosomal dominant leukodystrophy with autonomic symptoms.
Melberg, A., Hallberg, L., Kalimo, H., & Raininko, R. (2006) · PubMed Central · Cited by 76 · see citing works
Lipid alterations in apparently normal white matter in multiple sclerosis
Alling, C., Vanier, M.-T. ́., & Svennerholm, L. T. (1971) · Brain Research · doi:10.1016/0006-8993(71)90478-1 · Cited by 76 · see citing works
Assessment of the pathological grade of astrocytic gliomas using an MRI score
Asari, S., Makabe, T., Katayama, S., Itoh, T., Tsuchida, S., & Ohmoto, T. (1994) · Neuroradiology · doi:10.1007/bf00593267 · Cited by 75 · see citing works
Formalin fixed brains are useful for magnetic resonance imaging (MRI) study
Nagara, H., Inoue, T., Koga, T., Kitaguchi, T., Tateishi, J., & Goto, I. (1987) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(87)90184-5 · Cited by 75 · see citing works
MR imaging and proton MR spectroscopy in adult Krabbe disease.
Farina, L., Bizzi, A., Finocchiaro, G., Pareyson, D., Sghirlanzoni, A., Bertagnolio, B., Savoiardo, M., Naidu, S., Singhal, B. S., & Wenger, D. A. (2000) · PubMed Central · Cited by 75 · see citing works
Abnormalities in the Macroscopically Normal White Matter in Cases of Mild or Spinal Multiple Sclerosis (MS)
Allen, I. V., Glover, G., & Anderson, R. (1981) · Acta neuropathologica. Supplementum · doi:10.1007/978-3-642-81553-9_53 · Cited by 74 · see citing works
Pathological correlates of magnetization transfer imaging abnormalities in animal models and humans with multiple sclerosis.
Brochet, B., & Dousset, V. (1999) · PubMed · Cited by 74 · see citing works
Investigation of corpus callosum in schizophrenia with diffusion imaging
Brambilla, P., Cerini, R., Gasparini, A., Versace, A., Andreone, N., Vittorini, E., Barbui, C., Pelizza, L., Nosè, M., & Barlocco, L. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.04.012 · Cited by 74 · see citing works
Glial levels determine severity of white matter disease in Alzheimer's disease: a neuropathological study of glial changes
Sjöbeck, M., & Englund, E. M. (2003) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2003.00456.x · Cited by 73 · see citing works
Neuropathology: Methods and Diagnosis
Bailey, O. T. (1971) · JAMA · doi:10.1001/jama.1971.03180220086031 · Cited by 71 · see citing works
Magnetic resonance imaging, magnetisation transfer imaging, and diffusion weighted imaging correlates of optic nerve, brain, and cervical cord damage in Leber's hereditary optic neuropathy
Inglese, M. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.70.4.444 · Cited by 71 · see citing works
Normal-appearing White Matter in Patients with Phenylketonuria: Water Content, Myelin Water Fraction, and Metabolite Concentrations
Sirrs, S. M., Laule, C., Mädler, B., Brief, E., Tahir, S., Bishop, C., & MacKay, A. L. (2007) · Radiology · doi:10.1148/radiol.2421051758 · Cited by 71 · see citing works
Self-citation
Quantitative magnetization transfer imaging of pre-lesional white-matter changes in multiple sclerosis
Fazekas, F., Ropele, S., Enzinger, C., Seifert‐Held, T., & Strasser‐Fuchs, S. (2002) · Multiple Sclerosis Journal · doi:10.1191/1352458502ms860oa · Cited by 70 · see citing works
A comparison of magnetization transfer ratio, magnetization transfer rate, and the native relaxation time of water protons related to relapsing-remitting multiple sclerosis.
Ropele, S., Strasser‐Fuchs, S., Augustin, M., Stollberger, R., Enzinger, C., Hartung, H., & Fazekas, F. (2000) · PubMed Central · Cited by 70 · see citing works
Diffusion-weighted MR Imaging in Patients with Phenylketonuria: Relationship between Serum Phenylalanine Levels and ADC Values in Cerebral White Matter
Kono, K., Okano, Y., Nakayama, K., Hase, Y., Minamikawa, S., Ozawa, N., Yokote, H., & Inoue, Y. (2005) · Radiology · doi:10.1148/radiol.2362040611 · Cited by 69 · see citing works
Quantitative MRI‐pathology correlations of brain white matter lesions developing in a non‐human primate model of multiple sclerosis
Blezer, E. L. A., Bauer, J., Brok, H., Nicolay, K., & Hart, B. A. ‘. (2006) · NMR in Biomedicine · doi:10.1002/nbm.1085 · Cited by 69 · see citing works
Correlation of apparent myelin measures obtained in multiple sclerosis patients and controls from magnetization transfer and multicompartmental T2 analysis
Tozer, D. J., Davies, G. R., Altmann, D. R., Miller, D., & Tofts, P. S. (2005) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20479 · Cited by 68 · see citing works
Implications of lipid biology for the pathogenesis of schizophrenia
Berger, G. E., Wood, S. J., Pantelis, C., Velakoulis, D., Wellard, R. M., & McGorry, P. D. (2002) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2001.01021.x · Cited by 67 · see citing works
Structure of the Myelinated Axon
Trapp, B. D., & Kidd, G. J. (2004) · Elsevier eBooks · doi:10.1016/b978-012439510-7/50054-1 · Cited by 65 · see citing works
LIPID COMPOSITION OF HUMAN CEREBRAL WHITE MATTER AND MYELIN IN PHENYLKETONURIA1
Shah, S., Peterson, N. A., & McKean, C. M. (1972) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1972.tb01291.x · Cited by 65 · see citing works
Method for quantitative imaging of the macromolecular 1H fraction in tissues
Ropele, S., Seifert‐Held, T., Enzinger, C., & Fazekas, F. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10427 · Cited by 65 · see citing works
Quantitative proton magnetic resonance spectroscopy of the human cervical spinal cord at 3 tesla
Marliani, A. F., Clementi, V., Albini‐Riccioli, L., Agati, R., & Leonardi, M. (2006) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21113 · Cited by 64 · see citing works

Flagged first, then by citations

7 of the 291 references couldn’t be matched to a known paper.

Research works printed but not linked: 9

Van De Graff KM. Nervous tissue and the central nervous sys- tem. In: Van De Graff KM. Human Anatomy, 6th ed. New York: McGraw-Hill, 2002:351.
Gareau PJ, Rutt BK, Karlik SJ, Mitchell JR. Magnetization trans- fer and multicomponent T2 relaxation measurements with his- topathologic correlation in an experimental model of MS. J Magn Reson Imaging 2000;11:586 -595.
Vavasour IM, Whittall KP, Li DK, MacKay AL. Different mag- netization transfer effects exhibited by the short and long T(2) components in human brain. Magn Reson Med 2000;44:860 - 866.
Stanisz GJ, Kecojevic A, Bronskill MJ, Henkelman RM. Char- acterizing white matter with magnetization transfer and T(2). Magn Reson Med 1999;42:1128 -1136.
Fenrich FR, Beaulieu C, Allen PS. Relaxation times and micro- structures. NMR Biomed 2001;14:133-139.
Oakden W, Lobaugh NJ, Black SE, Stanisz GJ. T2 hyperintensity does not always mean demyelination (and neither does decreased fractional anisotropy). Proceedings from Imaging myelin: forma- tion, destruction and repair. Vancouver, Canada, 2006:P41.
Dula AN, Does MD, Gochberg DF. Proceedings from Imaging of myelin in ferret brain using magnetic resonance multi-component T2 and qMT. Imaging myelin: formation, destruction and repair. Vancouver, BC, 2006:P39.
Titelbaum DS, Frazier JL, Grossman RI, et al. Wallerian degen- eration and inflammation in rat peripheral nerve detected by in vivo MRI. AJNR Am J Neuroradiol 1989;10:741-746.
McGowan JC, Berman JI, Ford JC, et al. Characterization of experimental spinal cord injury with magnetization transfer ratio histograms. J Magn Reson Imaging 2000;12:247-254.

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Villalón‐Reina, J. E., Martínez, K., Qu, X., Ching, C. R. K., Nir, T. M., Kothapalli, D., Corbin, C. K., Sun, D., Lin, A., Forsyth, J. K., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0450-0 · Cited by 70 · see citing works
Sex differences in the human corpus callosum microstructure: A combined T2 myelin-water and diffusion tensor magnetic resonance imaging study
Liu, F., Vidarsson, L., Winter, J. D., Tran, H., & Kassner, A. (2010) · Brain Research · doi:10.1016/j.brainres.2010.04.064 · Cited by 65 · see citing works
The separate effects of lipids and proteins on brain MRI contrast revealed through tissue clearing
Leuze, C. W., Aswendt, M., Ferenczi, E., Liu, C. W., Hsueh, B., Goubran, M., Tian, Q., Steinberg, G. K., Zeineh, M., Deisseroth, K. A., et al. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.04.021 · Cited by 64 · see citing works
Magnetization transfer from inhomogeneously broadened lines (ihMT): Experimental optimization of saturation parameters for human brain imaging at 1.5 Tesla
Girard, O. M., Prévost, V., Varma, G., Cozzone, P. J., Alsop, D. C., & Duhamel, G. (2014) · Magnetic Resonance in Medicine · doi:10.1002/mrm.25330 · Cited by 62 · see citing works
Whole-Brain Myelin Imaging Using 3D Double-Echo Sliding Inversion Recovery Ultrashort Echo Time (DESIRE UTE) MRI
Ma, Y., Searleman, A. C., Jang, H., Wong, J., Chang, E. Y., Corey‐Bloom, J., Bydder, G. M., & Du, J. (2019) · Radiology · doi:10.1148/radiol.2019190911 · Cited by 61 · see citing works
White matter as a transport system
Paus, T., Pesaresi, M., & French, L. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.01.055 · Cited by 59 · see citing works
MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial
Caverzasi, E., Papinutto, N., Cordano, C., Kirkish, G., Gundel, T. J., Zhu, A. H., Akula, A. V., Boscardin, W. J., Neeb, H., Henry, R. G., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2217635120 · Cited by 59 · see citing works
Bayesian algorithm using spatial priors for multiexponentialT2relaxometry from multiecho spin echo MRI
Kumar, D., Nguyen, T. D., Gauthier, S. A., & Raj, A. (2012) · Magnetic Resonance in Medicine · doi:10.1002/mrm.24170 · Cited by 60 · see citing works
Decoding Diffusivity in Multiple Sclerosis: Analysis of Optic Radiation Lesional and Non-Lesional White Matter
Klistorner, A., Vootakuru, N., Wang, C., Yiannikas, C., Graham, S. L., Parratt, J., Garrick, R., Levin, N., Masters, L., Lagopoulos, J., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0122114 · Cited by 59 · see citing works
Microstructural imaging in the spinal cord and validation strategies
Cohen-Adad, J. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.04.009 · Cited by 50 · see citing works
Nanostructured Lipid‐Based Films for Substrate‐Mediated Applications in Biotechnology
Kang, M., Tuteja, M., Centrone, A., Topgaard, D., & Leal, C. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201704356 · Cited by 55 · see citing works
Silent zero TE MR neuroimaging: Current state-of-the-art and future directions
Ljungberg, E., Damestani, N. L., Wood, T., Lythgoe, D. J., Zelaya, F. O., Williams, S., Solana, A. B., Barker, G. J., & Wiesinger, F. (2021) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2021.03.002 · Cited by 55 · see citing works
Multi-Compartment T2 Relaxometry Using a Spatially Constrained Multi-Gaussian Model
Raj, A., Pandya, S., Shen, X., LoCastro, E., Nguyen, T. D., & Gauthier, S. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098391 · Cited by 54 · see citing works
Mapping microstructural gradients of the human striatum in normal aging and Parkinson’s disease
Drori, E., Berman, S., & Mezer, A. (2022) · Science Advances · doi:10.1126/sciadv.abm1971 · Cited by 53 · see citing works
Glial biomarkers in human central nervous system disease
Garden, G. A., & Campbell, B. M. (2016) · Glia · doi:10.1002/glia.22998 · Cited by 54 · see citing works
Gray matter T1‐w/T2‐w ratios are higher in Alzheimer's disease
Pelkmans, W., Dicks, E., Barkhof, F., Vrenken, H., Scheltens, P., van der Flier, W. M., & Tijms, B. M. (2019) · Human Brain Mapping · doi:10.1002/hbm.24638 · Cited by 53 · see citing works
Virtual histology of multi-modal magnetic resonance imaging of cerebral cortex in young men
Patel, Y., Shin, J., Drakesmith, M., Evans, J., Pausová, Z., & Paus, T. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116968 · Cited by 54 · see citing works
The effect of realistic geometries on the susceptibility‐weighted MR signal in white matter
Xu, T., Foxley, S., Kleinnijenhuis, M., Chen, W. C., & Miller, K. L. (2017) · Magnetic Resonance in Medicine · doi:10.1002/mrm.26689 · Cited by 53 · see citing works
Studying brain microstructure with magnetic susceptibility contrast at high-field
Duyn, J. H. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.02.046 · Cited by 51 · see citing works
Testosterone and estrogen in multiple sclerosis: from pathophysiology to therapeutics
Collongues, N., Patte‐Mensah, C., Seze, J. D., Mensah‐Nyagan, A. G., & Derfuss, T. J. (2018) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2018.1481390 · Cited by 51 · see citing works
Myelin Water Atlas: A Template for Myelin Distribution in the Brain
Liu, H., Rubino, C., Dvorak, A. V., Jarrett, M., Ljungberg, E., Vavasour, I. M., Lee, L. E., Kolind, S., MacMillan, E. L., Traboulsee, A. L., et al. (2019) · Journal of Neuroimaging · doi:10.1111/jon.12657 · Cited by 51 · see citing works
Self-citation
Mediation of Developmental Risk Factors for Psychosis by White Matter Microstructure in Young Adults With Psychotic Experiences
Drakesmith, M., Dutt, A., Fonville, L., Zammit, S., Reichenberg, A., Evans, J., Lewis, G., Jones, D. K., & David, A. S. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.3375 · Cited by 50 · see citing works
Mechanisms of T2* anisotropy and gradient echo myelin water imaging
Lee, J., Nam, Y., Choi, J. Y., Kim, E. Y., Oh, S., & Kim, D. (2016) · NMR in Biomedicine · doi:10.1002/nbm.3513 · Cited by 49 · see citing works
Towards quantification of myelin by solid-state MRI of the lipid matrix protons
Seifert, A. C., Li, C., Wilhelm, M. J., Wehrli, S. L., & Wehrli, F. W. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.09.054 · Cited by 49 · see citing works
Modeling and Quantifying Biochemical Changes in C6 Tumor Gliomas by Fourier Transform Infrared Imaging
Beljebbar, A., Amharref, N., Lévèques, A., Dukic, S., Ventéo, L., Schneider, L., Pluot, M., & Manfait, M. (2008) · Analytical Chemistry · doi:10.1021/ac800990y · Cited by 48 · see citing works
Advances in MRI of the myelin bilayer
Weiger, M., Froidevaux, R., Baadsvik, E. L., Brunner, D. O., Rösler, M. B., & Pruessmann, K. P. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116888 · Cited by 48 · see citing works
Understanding aqueous and non-aqueous proton T1 relaxation in brain
Manning, A. P., MacKay, A. L., & Michal, C. A. (2021) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2020.106909 · Cited by 47 · see citing works
Self-citation
Hypothyroidism and mood disorders: integrating novel insights from brain imaging techniques
Pilhatsch, M., Marxen, M., Winter, C., Smolka, M. N., & Bauer, M. (2011) · Thyroid Research · doi:10.1186/1756-6614-4-s1-s3 · Cited by 46 · see citing works
The future of functionally-related structural change assessment
Johansen-Berg, H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.10.073 · Cited by 45 · see citing works
Reproducibility of in vivo magnetic resonance imaging–based measurement of myelin water
Levesque, I. R., Chia, C. L. L., & Pike, G. B. (2010) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22170 · Cited by 45 · see citing works
How does magnetization transfer influence mc DESPOT results?
Zhang, J., Kolind, S., Laule, C., & MacKay, A. L. (2014) · Magnetic Resonance in Medicine · doi:10.1002/mrm.25520 · Cited by 45 · see citing works
Self-citation
On the merits of non-invasive myelin imaging in epilepsy, a literature review
Drenthen, G. S., Backes, W. H., Aldenkamp, A. P., Vermeulen, R. J., Klinkenberg, S., & Jansen, J. F. A. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.108687 · Cited by 45 · see citing works
Simultaneous measurement of total water content and myelin water fraction in brain at 3 T using a T 2 relaxation based method
Meyers, S. M., Kolind, S., & MacKay, A. L. (2016) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2016.12.001 · Cited by 44 · see citing works
Self-citation
Myelin vs Axon Abnormalities in White Matter in Bipolar Disorder
Lewandowski, K. E., Öngür, D., Sperry, S. H., Cohen, B. M., Sehovic, S., Goldbach, J. R., & Du, F. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.310 · Cited by 43 · see citing works
Rapid measurement of brain macromolecular proton fraction with transient saturation transfer MRI
van Gelderen, P., Jiang, X., & Duyn, J. H. (2016) · Magnetic Resonance in Medicine · doi:10.1002/mrm.26304 · Cited by 43 · see citing works
In vivo characterization of brain ultrashort‐T2 components
Boucneau, T., Cao, P., Tang, S., Han, M., Xu, D., Henry, R. G., & Larson, P. E. Z. (2017) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27037 · Cited by 43 · see citing works
Longitudinal monitoring of metabolic alterations in cuprizone mouse model of multiple sclerosis using 1H-magnetic resonance spectroscopy
Orije, J. E. M. J., Kara, F., Guglielmetti, C., Praet, J., der Linden, A. V., Ponsaerts, P., & Verhoye, M. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.04.012 · Cited by 41 · see citing works
Strain differences in cuprizone induced demyelination
Yu, Q., Hui, R., Park, J., Huang, Y., Kusnecov, A. W., Dreyfus, C. F., & Zhou, R. (2017) · Cell & Bioscience · doi:10.1186/s13578-017-0181-3 · Cited by 40 · see citing works
Transplanted human glial-restricted progenitors can rescue the survival of dysmyelinated mice independent of the production of mature, compact myelin
Lyczek, A., Arnold, A., Zhang, J., Campanelli, J. T., Janowski, M., Bulte, J. W. M., & Walczak, P. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.02.005 · Cited by 40 · see citing works
Reversible reduction in brain myelin content upon marathon running
Ramos‐Cabrer, P., Cabrera‐Zubizarreta, A., Padró, D., Matute‐González, M., Rodríguez-Antigüedad, A., & Matute, C. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01244-7 · Cited by 41 · see citing works
Neurocognitive Late Effects of Chemotherapy in Survivors of Acute Lymphoblastic Leukemia: Focus on Methotrexate.
van der Plas, E. A. A., Nieman, B. J., Butcher, D. T., Hitzler, J. K., Weksberg, R., Ito, S., & Schachar, R. J. (2015) · Europe PMC (PubMed Central) · Cited by 40 · see citing works
Does hydration status affect MRI measures of brain volume or water content?
Meyers, S. M., Tam, R. C., Lee, J. S., Kolind, S., Vavasour, I. M., Mackie, E., Zhao, Y., Laule, C., Mädler, B., Li, D. K. B., et al. (2016) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.25168 · Cited by 38 · see citing works
Self-citation

Myelin Water Imaging
MacKay, A. L., & Laule, C. (1996) · Encyclopedia of Magnetic Resonance · doi:10.1002/9780470034590.emrstm1270 · Cited by 4 · see citing works
Self-citation
Advances in noninvasive myelin imaging
Heath, F. C., Hurley, S. A., Johansen‐Berg, H., & Sampaio‐Baptista, C. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22552 · Cited by 130 · see citing works
Myelin-sensitive inversion recovery (MySIR) for quantification of myelin in the peripheral nerve
Sada, T., Yokota, H., Nitta, K., Kurosawa, R., Sato, H., Matsumoto, K., Namiki, T., Yoneyama, M., Gilbert, G., Masuda, Y., et al. (2024) · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · doi:10.58530/2024/1885
Magnetic Resonance of Myelin Water: An in vivo Marker for Myelin
MacKay, A. L., & Laule, C. (2016) · Brain Plasticity · doi:10.3233/bpl-160033 · Cited by 288 · see citing works
Self-citation
Magnetic resonance of myelin, myelination, and myelin disorders
van der Knaap, M. S., & Valk, J. (1995)

Authors: Laule, C., Vavasour, I. M., Kolind, S. H., Li, D. K. B., Traboulsee, T. L., Moore, G. R. W., & MacKay, A. L.
Affiliations: University of British Columbia (CA)
University of British Columbia Hospital (CA)
Corresponding author: Laule, Cornelia
ORCID: Laule, Cornelia
Vavasour, Irene M.
Kolind, Shannon H.
Li, David K.B.
MacKay, Alex L.
Venue: Neurotherapeutics
Publisher: Elsevier BV
Published: 2007-07
Volume: 4
Issue: 3
Pages: 460-484
ISSN: 1878-7479 (ISSN-L)
DOI: 10.1016/j.nurt.2007.05.004
PMC: PMC7479725
OpenAlex: W2080423736
Cited by: 334
References: 291
Citations by year: 2026: 9 · 2025: 17 · 2024: 20 · 2023: 19 · 2022: 17 · 2021: 28 · 2020: 32 · 2019: 28 · 2018: 23 · 2017: 27 · 2016: 16 · 2015: 17 · 2014: 18 · 2013: 15 · 2012: 8
FWCI: 1.15
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5886 d)
Locations: Neurotherapeutics (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Multiple Sclerosis Society of Canada
Multiple Sclerosis Society
Topics: Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
Keywords: myelin imaging, myelin, myelination, myelin damage, remyelination, MR spectroscopy, diffusion MRI, magnetization transfer, T2 relaxation, peripheral nerves
MeSH terms: Animals, Humans, Magnetic Resonance Imaging, Myelin Sheath

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