The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study
Open accessAbstract
BACKGROUND: The association between intraoperative cardiovascular changes and perioperative myocardial injury has chiefly focused on hypotension during noncardiac surgery. However, the relative influence of blood pressure and heart rate (HR) remains unclear. We investigated both individual and codependent relationships among intraoperative HR, systolic blood pressure (SBP), and myocardial injury after noncardiac surgery (MINS). METHODS: Secondary analysis of the Vascular Events in Noncardiac Surgery Cohort Evaluation (VISION) study, a prospective international cohort study of noncardiac surgical patients. Multivariable logistic regression analysis tested for associations between intraoperative HR and/or SBP and MINS, defined by an elevated serum troponin T adjudicated as due to an ischemic etiology, within 30 days after surgery. Predefined thresholds for intraoperative HR and SBP were: maximum HR >100 beats or minimum HR <55 beats per minute (bpm); maximum SBP >160 mm Hg or minimum SBP <100 mm Hg. Secondary outcomes were myocardial infarction and mortality within 30 days after surgery. RESULTS: After excluding missing data, 1197 of 15,109 patients (7.9%) sustained MINS, 454 of 16,031 (2.8%) sustained myocardial infarction, and 315 of 16,061 patients (2.0%) died within 30 days after surgery. Maximum intraoperative HR >100 bpm was associated with MINS (odds ratio [OR], 1.27 [1.07–1.50]; P < .01), myocardial infarction (OR, 1.34 [1.05–1.70]; P = .02), and mortality (OR, 2.65 [2.06–3.41]; P < .01). Minimum SBP <100 mm Hg was associated with MINS (OR, 1.21 [1.05–1.39]; P = .01) and mortality (OR, 1.81 [1.39–2.37]; P < .01), but not myocardial infarction (OR, 1.21 [0.98–1.49]; P = .07). Maximum SBP >160 mm Hg was associated with MINS (OR, 1.16 [1.01–1.34]; P = .04) and myocardial infarction (OR, 1.34 [1.09–1.64]; P = .01) but, paradoxically, reduced mortality (OR, 0.76 [0.58–0.99]; P = .04). Minimum HR <55 bpm was associated with reduced MINS (OR, 0.70 [0.59–0.82]; P < .01), myocardial infarction (OR, 0.75 [0.58–0.97]; P = .03), and mortality (OR, 0.58 [0.41–0.81]; P < .01). Minimum SBP <100 mm Hg with maximum HR >100 bpm was more strongly associated with MINS (OR, 1.42 [1.15–1.76]; P < .01) compared with minimum SBP <100 mm Hg alone (OR, 1.20 [1.03–1.40]; P = .02). CONCLUSIONS: Intraoperative tachycardia and hypotension are associated with MINS. Further interventional research targeting HR/blood pressure is needed to define the optimum strategy to reduce MINS.
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Third Universal Definition of Myocardial Infarction
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Third universal definition of myocardial infarction
the Writing Group on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction, Thygesen, K., Alpert, J. S., Jaffe, A. S., Simoons, M. L., Chaitman, B. R., & White, H. D. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.122 · Cited by 2,053
Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations
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Self-citationMortality after surgery in Europe: a 7 day cohort study
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Sessler, D. I., Bloomstone, J. A., Aronson, S., Berry, C., Gan, T. J., Kellum, J. A., Plumb, J., Mythen, M. G., Grocott, M. P. W., Edwards, M. R., et al. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.01.013 · Cited by 687
Self-citationAge of patients undergoing surgery
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Self-citationKe, J. X. C., McIsaac, D. I., George, R. B., Branco, P., Cook, E. F., Beattie, W. S., Urquhart, R., & MacDonald, D. B. (2022) · Canadian Journal of Anesthesia/Journal canadien d'anesthésie · doi:10.1007/s12630-022-02287-0 · Cited by 6
Metadata
- Authors
- Abbott, T. E. F., Pearse, R. M., Archbold, R. A., Ahmad, T., Niebrzegowska, E., Wragg, A., Rodseth, R. N., Devereaux, P. J., & Ackland, G. L.
- Venue
- Anesthesia & Analgesia
- Published
- 2018-06
- Volume
- 126
- Issue
- 6
- Pages
- 1936-1945
- ISSN
- 0003-2999 (ISSN-L)
- OpenAlex
- W2765988597
- Cited by
- 265
- References
- 42
- FWCI
- 11.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
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