The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Parallels between tissue repair and embryo morphogenesis
Abstract
Wound healing involves a coordinated series of tissue movements that bears a striking resemblance to various embryonic morphogenetic episodes. There are several ways in which repair recapitulates morphogenesis. We describe how almost identical cytoskeletal machinery is used to repair an embryonic epithelial wound as is involved during the morphogenetic episodes of dorsal closure in Drosophila and eyelid fusion in the mouse foetus. For both naturally occurring and wound-activated tissue movements, JNK signalling appears to be crucial, as does the tight regulation of associated cell divisions and adhesions. In the embryo, both morphogenesis and repair are achieved with a perfect end result, whereas repair of adult tissues leads to scarring. We discuss whether this may be due to the adult inflammatory response, which is absent in the embryo.
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Cites
Burgoyne, R. D., & Morgan, A. (2003) · Physiological Reviews · doi:10.1152/physrev.00031.2002 · Cited by 934
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
Ashcroft, G. S., Yang, X., Glick, A. B., Weinstein, M., Letterio, J. J., Mizel, D. E., Anzano, M., Greenwell-Wild, T., Wahl, S. M., Deng, C., et al. (1999) · Nature Cell Biology · doi:10.1038/12971 · Cited by 911
Accelerated wound closure in neutrophil-depleted mice
Dovi, J. V., He, L.-K., & DiPietro, L. A. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0802406 · Cited by 525
Wound healing recapitulates morphogenesis in Drosophila embryos
Wood, W., Jacinto, A., Grose, R., Woolner, S., Gale, J., Wilson, C., & Martin, P. (2002) · Nature Cell Biology · doi:10.1038/ncb875 · Cited by 435
Self-citationJNK Signaling Pathway Is Required for Efficient Wound Healing in Drosophila
Rämet, M., Lanot, R., Zachary, D., & Manfruelli, P. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0502 · Cited by 313
Cited by
Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
α-Catenin as a tension transducer that induces adherens junction development
Yonemura, S., Wada, Y., Watanabe, T., Nagafuchi, A., & Shibata, M. (2010) · Nature Cell Biology · doi:10.1038/ncb2055 · Cited by 972
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves
Cattin, A.-L., Burden, J. J., Van Emmenis, L., Mackenzie, F. E., Hoving, J. J. A., Garcia Calavia, N., Guo, Y., McLaughlin, M., Rosenberg, L. H., Quereda, V., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.021 · Cited by 936
Calcium flickers steer cell migration
Wei, C., Wang, X., Chen, M., Ouyang, K., Song, L.-S., & Cheng, H. (2009) · Nature · doi:10.1038/nature07577 · Cited by 611
Regenerative endodontics: a comprehensive review
Kim, S. G., Malek, M., Sigurdsson, A., Lin, L. M., & Kahler, B. (2018) · International Endodontic Journal · doi:10.1111/iej.12954 · Cited by 523
Metadata
- Authors
- Martin, P., & Parkhurst, S. M.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2004-07-01
- Volume
- 131
- Issue
- 13
- Pages
- 3021-3034
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2080597378
- Cited by
- 565
- References
- 5
- FWCI
- 24.85
- Type
- journal article
- Language
- en
- Open access
- closed
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