The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
The roles of cilia in developmental disorders and disease
Abstract
Cilia are highly conserved organelles that have diverse motility and sensory functions. Recent discoveries have revealed that cilia also have crucial roles in cell signaling pathways and in maintaining cellular homeostasis. As such, defects in cilia formation or function have profound effects on the development of body pattern and the physiology of multiple organ systems. By categorizing syndromes that are due to cilia dysfunction in humans and from studies in vertebrate model organisms, molecular pathways that intersect with cilia formation and function have come to light. Here, we summarize an emerging view that in order to understand some complex developmental pathways and disease etiologies, one must consider the molecular functions performed by cilia.
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Cites
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Cited by
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Teratozoospermia: spotlight on the main genetic actors in the human
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Primary cilium-dependent signaling mechanisms
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Metadata
- Authors
- Bisgrove, B. W., & Yost, H. J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2006-11-01
- Volume
- 133
- Issue
- 21
- Pages
- 4131-4143
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2163035368
- Cited by
- 347
- References
- 15
- FWCI
- 16.43
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
