The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The role of FGF/Erk signaling in pluripotent cells
Abstract
Fibroblast growth factor (FGF) signaling controls fundamental processes such as proliferation, differentiation and migration throughout mammalian development. Here we discuss recent discoveries that implicate FGF/Erk signaling in the control of pluripotency and lineage specification in several different stem cell states, including the separation of pluripotent epiblast and primitive endoderm in the blastocyst, the lineage priming of embryonic stem (ES) cells, and in the stabilization of the metastable state of mouse epiblast and human ES cells. Understanding how extrinsic signals such as FGF regulate different stem cell states will be crucial to harvest the clinical promise of induced pluripotent and embryo-derived stem cells.
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Cites
The ground state of embryonic stem cell self-renewal
Ying, Q.-L., Wray, J., Nichols, J., Batlle-Morera, L., Doble, B., Woodgett, J., Cohen, P., & Smith, A. (2008) · Nature · doi:10.1038/nature06968 · Cited by 3,442
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Self-citationA parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
Niwa, H., Ogawa, K., Shimosato, D., & Adachi, K. (2009) · Nature · doi:10.1038/nature08113 · Cited by 872
FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations
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An essential function of the mitogen‐activated protein kinase Erk2 in mouse trophoblast development
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Stavridis, M. P., Collins, B. J., & Storey, K. G. (2010) · Development · doi:10.1242/dev.043117 · Cited by 124 · cited 2×
“support a neuronal suppression function of FGF in EpiSCs (Stavridis et al., 2010).”
Background
Cited by
The Fibroblast Growth Factor signaling pathway
Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq
Blakeley, P., Fogarty, N. M. E., del Valle, I., Wamaitha, S. E., Hu, T. X., Elder, K., Snell, P., Christie, L., Robson, P., & Niakan, K. K. (2015) · Development · doi:10.1242/dev.123547 · Cited by 466
Tissue Stem Cells: Architects of Their Niches
Fuchs, E., & Blau, H. M. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.09.011 · Cited by 332
Bifurcation analysis of single-cell gene expression data reveals epigenetic landscape
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Ohnishi, Y., Huber, W., Tsumura, A., Kang, M., Xenopoulos, P., Kurimoto, K., Oleś, A. K., Araúzo-Bravo, M. J., Saitou, M., Hadjantonakis, A.-K., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb2881 · Cited by 300
Kang, M., Piliszek, A., Artus, J., & Hadjantonakis, A.-K. (2013) · Development · doi:10.1242/dev.084996 · Cited by 284
Differentiation of cardiomyocytes and generation of human engineered heart tissue
Breckwoldt, K., Letuffe-Brenière, D., Mannhardt, I., Schulze, T., Ulmer, B., Werner, T., Benzin, A., Klampe, B., Reinsch, M. C., Laufer, S., et al. (2017) · Nature Protocols · doi:10.1038/nprot.2017.033 · Cited by 272
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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency
Yang, P., Humphrey, S. J., Cinghu, S., Pathania, R., Oldfield, A. J., Kumar, D., Perera, D., Yang, J. Y. H., James, D. E., Mann, M., et al. (2019) · Cell Systems · doi:10.1016/j.cels.2019.03.012 · Cited by 146
Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues
Moore, R., Cai, K. Q., Tao, W., Smith, E. R., & Xu, X.-X. (2013) · BMC Developmental Biology · doi:10.1186/1471-213x-13-39 · Cited by 41
Cadherins in early neural development
Punovuori, K., Malaguti, M., & Lowell, S. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03815-9 · Cited by 39
Athanasouli, P., Balli, M., De Jaime-Soguero, A., Boel, A., Papanikolaou, S., van der Veer, B. K., Janiszewski, A., Vanhessche, T., Francis, A., El Laithy, Y., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36914-1 · Cited by 31
Metadata
- Authors
- Lanner, F., & Rossant, J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2010-10-15
- Volume
- 137
- Issue
- 20
- Pages
- 3351-3360
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1990180850
- Cited by
- 408
- References
- 6
- FWCI
- 11.81
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
