Tissue Stem Cells: Architects of Their Niches

Innate immune recognition

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Integrin signaling

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SATELLITE CELL OF SKELETAL MUSCLE FIBERS

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Regulatory T cells: mechanisms of differentiation and function

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Defining trained immunity and its role in health and disease

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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

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PRDM16 controls a brown fat/skeletal muscle switch

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Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

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Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

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Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

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Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

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Asymmetric self-renewal and commitment of satellite stem cells in muscle

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An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

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Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

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Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

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Distinct fibroblast lineages determine dermal architecture in skin development and repair

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NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

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Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

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A Special Population of Regulatory T Cells Potentiates Muscle Repair

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Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit

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BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

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Permanent Coverage of Large Burn Wounds with Autologous Cultured Human Epithelium

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A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

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Molecular regulation of stem cell quiescence

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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

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Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

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An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

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Direct Isolation of Satellite Cells for Skeletal Muscle Regeneration

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Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

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Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

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YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

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Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding

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In vivo gene editing in dystrophic mouse muscle and muscle stem cells

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Yap1 acts downstream of α-catenin to control epidermal proliferation

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Permanent coverage of large burn wounds with autologous cultured human epithelium

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Haematopoietic stem cell activity and interactions with the niche

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Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

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Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

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Self-renewal and expansion of single transplanted muscle stem cells

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Dominant role of the niche in melanocyte stem-cell fate determination

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The aged niche disrupts muscle stem cell quiescence

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MyoD and the transcriptional control of myogenesis

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Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

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A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

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Stem cell patterning and fate in human epidermis

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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

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Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

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Reparative inflammation takes charge of tissue regeneration

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The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

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Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

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Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

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Regulation of Muscle Growth and Regeneration by the Immune System

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Regeneration of the entire human epidermis using transgenic stem cells

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A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

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Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation

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Topographically Distinct Epidermal Nociceptive Circuits Revealed by Axonal Tracers Targeted to Mrgprd

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Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

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A Role for Skin γδ T Cells in Wound Repair

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Mutations in the laminin α2–chain gene (LAMA2) cause merosin–deficient congenital muscular dystrophy

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Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle

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Effective fiber hypertrophy in satellite cell-depleted skeletal muscle

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Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division

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Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

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The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

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p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

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In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

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Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skinPreprint

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Hair follicle stem cells are specified and function in early skin morphogenesis

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Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

Amoasii, L., Hildyard, J. C. W., Li, H., Sanchez-Ortiz, E., Mireault, A., Caballero, D., Harron, R., Stathopoulou, T.-R., Massey, C., Shelton, J. M., et al. (2018) · Science · doi:10.1126/science.aau1549 · Cited by 546 · see citing works

Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

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Niche stiffness underlies the ageing of central nervous system progenitor cells

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Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

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A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

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The plasticity and stability of regulatory T cells

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Collagen VI regulates satellite cell self-renewal and muscle regeneration

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A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division

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Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells

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Satellite cells, the engines of muscle repair

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Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis

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Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles

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Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth

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