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Cited by 263

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The stem cell niche: lessons from the Drosophila testis

Open access
de Cuevas, Margaret, Matunis, Erika L.·2011·Development

Abstract

In metazoans, tissue maintenance and regeneration depend on adult stem cells, which are characterized by their ability to self-renew and generate differentiating progeny in response to the needs of the tissues in which they reside. In the Drosophila testis, germline and somatic stem cells are housed together in a common niche, where they are regulated by local signals, epigenetic mechanisms and systemic factors. These stem cell populations in the Drosophila testis have the unique advantage of being easy to identify and manipulate, and hence much progress has been made in understanding how this niche operates. Here, we summarize recent work on stem cells in the adult Drosophila testis and discuss the remarkable ability of these stem cells to respond to change within the niche.

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Crossref · 10.1242/dev.056242

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Metadata

Authors
de Cuevas, M., & Matunis, E. L.
Venue
Development
Published
2011-07-15
Volume
138
Issue
14
Pages
2861-2869
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2104031957
Cited by
263
References
1
FWCI
7.05
Type
journal article
Language
en
Open access
bronze

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