The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Brassinosteroids control meristem size by promoting cell cycle progression in Arabidopsis roots
Open accessAbstract
Brassinosteroids (BRs) play crucial roles in plant growth and development. Previous studies have shown that BRs promote cell elongation in vegetative organs in several plant species, but their contribution to meristem homeostasis remains unexplored. Our analyses report that both loss- and gain-of-function BR-related mutants in Arabidopsis thaliana have reduced meristem size, indicating that balanced BR signalling is needed for the optimal root growth. In the BR-insensitive bri1-116 mutant, the expression pattern of the cell division markers CYCB1;1, ICK2/KRP2 and KNOLLE revealed that a decreased mitotic activity accounts for the reduced meristem size; accordingly, this defect could be overcome by the overexpression of CYCD3;1. The activity of the quiescent centre (QC) was low in the short roots of bri1-116, as reported by cell type-specific markers and differentiation phenotypes of distal stem cells. Conversely, plants treated with the most active BR, brassinolide, or mutants with enhanced BR signalling, such as bes1-D, show a premature cell cycle exit that results in early differentiation of meristematic cells, which also negatively influence meristem size and overall root growth. In the stem cell niche, BRs promote the QC renewal and differentiation of distal stem cells. Together, our results provide evidence that BRs play a regulatory role in the control of cell-cycle progression and differentiation in the Arabidopsis root meristem.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., Offringa, R., & Jürgens, G. (2003) · Nature · doi:10.1038/nature02085 · Cited by 1,894
A Putative Leucine-Rich Repeat Receptor Kinase Involved in Brassinosteroid Signal Transduction
Li, J., & Chory, J. (1997) · Cell · doi:10.1016/s0092-8674(00)80357-8 · Cited by 1,650
Cellular organisation of the Arabidopsis thaliana root
Dolan, L., Janmaat, K., Willemsen, V., Linstead, P., Poethig, S., Roberts, K., & Scheres, B. (1993) · Development · doi:10.1242/dev.119.1.71 · Cited by 1,462
Li, J., Wen, J., Lease, K. A., Doke, J. T., Tax, F. E., & Walker, J. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00812-7 · Cited by 1,446
An Auxin-Dependent Distal Organizer of Pattern and Polarity in the Arabidopsis Root
Sabatini, S., Beis, D., Wolkenfelt, H., Murfett, J., Guilfoyle, T., Malamy, J., Benfey, P., Leyser, O., Bechtold, N., Weisbeek, P., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81535-4 · Cited by 1,388
Yin, Y., Wang, Z.-Y., Mora-Garcia, S., Li, J., Yoshida, S., Asami, T., & Chory, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00721-3 · Cited by 1,283
A Gene Expression Map of the Arabidopsis Root
Birnbaum, K., Shasha, D. E., Wang, J. Y., Jung, J. W., Lambert, G. M., Galbraith, D. W., & Benfey, P. N. (2003) · Science · doi:10.1126/science.1090022 · Cited by 1,258
BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
Nam, K. H., & Li, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00814-0 · Cited by 1,217
The PLETHORA Genes Mediate Patterning of the Arabidopsis Root Stem Cell Niche
Aida, M., Beis, D., Heidstra, R., Willemsen, V., Blilou, I., Galinha, C., Nussaume, L., Noh, Y.-S., Amasino, R., & Scheres, B. (2004) · Cell · doi:10.1016/j.cell.2004.09.018 · Cited by 1,213
A High-Resolution Root Spatiotemporal Map Reveals Dominant Expression Patterns
Brady, S. M., Orlando, D. A., Lee, J.-Y., Wang, J. Y., Koch, J., Dinneny, J. R., Mace, D., Ohler, U., & Benfey, P. N. (2007) · Science · doi:10.1126/science.1146265 · Cited by 1,182
Cited by
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
The molecular circuitry of brassinosteroid signaling
Belkhadir, Y., & Jaillais, Y. (2015) · New Phytologist · doi:10.1111/nph.13269 · Cited by 255
Brassinosteroids regulate organ boundary formation in the shoot apical meristem of Arabidopsis
Gendron, J. M., Liu, J.-S., Fan, M., Bai, M.-Y., Wenkel, S., Springer, P. S., Barton, M. K., & Wang, Z.-Y. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210799110 · Cited by 205
Bell, E. M., Lin, W.-C., Husbands, A. Y., Yu, L., Jaganatha, V., Jablonska, B., Mangeon, A., Neff, M. M., Girke, T., & Springer, P. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210789109 · Cited by 194
Defence on demand: mechanisms behind optimal defence patterns
Meldau, S., Erb, M., & Baldwin, I. T. (2012) · Annals of Botany · doi:10.1093/aob/mcs212 · Cited by 197
Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis
(2024) · doi:10.1083/jcb.202311125 · Cited by 6
Metadata
- Authors
- González-García, M.-P., Vilarrasa-Blasi, J., Zhiponova, M., Divol, F., Mora-García, S., Russinova, E., & Caño-Delgado, A. I.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2011-03-01
- Volume
- 138
- Issue
- 5
- Pages
- 849-859
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2062376345
- Cited by
- 522
- References
- 65
- FWCI
- 42.86
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
