Defence on demand: mechanisms behind optimal defence patterns

Meldau, Stefan; Erb, Matthias; Baldwin, Ian T.

doi:10.1093/aob/mcs212

Cited by 197Insect-Plant Interactions and ControlPlant-Microbe Interactions and ImmunityPlant biochemistry and biosynthesis

Defence on demand: mechanisms behind optimal defence patterns

Open access

Meldau, Stefan, Erb, Matthias, Baldwin, Ian T.·2012·Annals of Botany

DOI 10.1093/aob/mcs212PMC PMC3503495

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: The optimal defence hypothesis (ODH) predicts that tissues that contribute most to a plant's fitness and have the highest probability of being attacked will be the parts best defended against biotic threats, including herbivores. In general, young sink tissues and reproductive structures show stronger induced defence responses after attack from pathogens and herbivores and contain higher basal levels of specialized defensive metabolites than other plant parts. However, the underlying physiological mechanisms responsible for these developmentally regulated defence patterns remain unknown. SCOPE: This review summarizes current knowledge about optimal defence patterns in above- and below-ground plant tissues, including information on basal and induced defence metabolite accumulation, defensive structures and their regulation by jasmonic acid (JA). Physiological regulations underlying developmental differences of tissues with contrasting defence patterns are highlighted, with a special focus on the role of classical plant growth hormones, including auxins, cytokinins, gibberellins and brassinosteroids, and their interactions with the JA pathway. By synthesizing recent findings about the dual roles of these growth hormones in plant development and defence responses, this review aims to provide a framework for new discoveries on the molecular basis of patterns predicted by the ODH. CONCLUSIONS: Almost four decades after its formulation, we are just beginning to understand the underlying molecular mechanisms responsible for the patterns of defence allocation predicted by the ODH. A requirement for future advances will be to understand how developmental and defence processes are integrated.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1093/aob/mcs212

Cites

0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A drop in secondary metabolite levels a few weeks after germination or at the onset of flowering may reflect an increased need of primary metabolites and nutrients rather than a drop in herbivore pressure.
“A drop in secondary metabolite levels, as is often observed a few weeks after germination or at the onset of flowering, for instance (Meldau et al., 2012;Barton and Boege, 2017), may reflect an increased need of primary metabolites and nutrients rather than a drop in herbivore pressure.”
From Plant Secondary Metabolites as Defenses, Regulators, and Primary Metabolites: The Blurred Functional Trichotomy (2020) · cites this paper as Meldau et al., 2012
The sections ‘Secondary metabolite concentrations are highest in young tissues’ and ‘Developmental aspects of defensive patterns’ report higher levels in young leaves and a decline in one maize defence metabolite as plants mature. They do not establish a general drop a few weeks after germination or in secondary-metabolite levels at flowering; the flowering example concerns reduced defence inducibility. The proposed explanation after the citations appears to be the citing authors’ interpretation, not a claim attributed to Meldau et al. (LLM, conf=0.83)
Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
Thines, B. C., Katsir, L., Melotto, M., Niu, Y., Mandaokar, A. D., Liu, G., Nomura, K., He, S. Y., Howe, G. A., & Browse, J. (2007) · Nature · doi:10.1038/nature05960 · Cited by 2,512 · see citing works
Plant Immunity to Insect Herbivores
Howe, G. A., & Jander, G. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092825 · Cited by 2,432 · see citing works
The JAZ family of repressors is the missing link in jasmonate signalling
Chini, A., Fonseca, S., Santos-Fernandez, G., Adie, B. A. T., Chico, J. M., Lorenzo, Ó., García‐Casado, G., López‐Vidriero, I., Lozano, F. M., Ponce, M. R., et al. (2007) · Nature · doi:10.1038/nature06006 · Cited by 2,427 · see citing works
Gibberellin Metabolism and its Regulation
Yamaguchi, S. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092804 · Cited by 2,204 · see citing works
The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots
Blilou, I., Xu, J., Wildwater, M., Willemsen, V., Paponov, I. A., Friml, J., Heidstra, R., Aida, M., Palme, K. J., & Scheres, B. (2005) · Nature · doi:10.1038/nature03184 · Cited by 2,023 · see citing works
Hormone Crosstalk in Plant Disease and Defense: More Than Just JASMONATE-SALICYLATE Antagonism
Robert‐Seilaniantz, A., Grant, M., & Jones, J. D. G. (2011) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-073009-114447 · Cited by 1,929 · see citing works
Cytokinin-Deficient Transgenic Arabidopsis Plants Show Multiple Developmental Alterations Indicating Opposite Functions of Cytokinins in the Regulation of Shoot and Root Meristem Activity
Werner, T., Motyka, V., Laucou, V., Smets, R., Onckelen, H. A. V., & Schmülling, T. (2003) · The Plant Cell · doi:10.1105/tpc.014928 · Cited by 1,525 · see citing works
BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling
Li, J., Wen, J., Lease, K. A., Doke, J. T., Tax, F. E., & Walker, J. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00812-7 · Cited by 1,450 · see citing works
A molecular framework for light and gibberellin control of cell elongation
de Lucas, M., Davière, J., Rodríguez-Falcón, M., Pontín, M., Iglesias‐Pedraz, J. M., Lorrain, S., Fankhauser, C., Blázquez, M. A., Titarenko, E., & Prat, S. (2008) · Nature · doi:10.1038/nature06520 · Cited by 1,320 · see citing works
GIBBERELLIN INSENSITIVE DWARF1 encodes a soluble receptor for gibberellin
Ueguchi‐Tanaka, M., Ashikari, M., Nakajima, M., Itoh, H., Katoh, E., Kobayashi, M., Chow, T., Hsing, Y.-I. C., Kitano, H., Yamaguchi, I., et al. (2005) · Nature · doi:10.1038/nature04028 · Cited by 1,313 · see citing works
BES1 Accumulates in the Nucleus in Response to Brassinosteroids to Regulate Gene Expression and Promote Stem Elongation
Yin, Y., Wang, Z., Mora‐García, S., Li, J., Yoshida, S., Asami, T., & Chory, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00721-3 · Cited by 1,287 · see citing works
The evolutionary context for herbivore-induced plant volatiles: beyond the ‘cry for help’
Dicke, M., & Baldwin, I. T. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2009.12.002 · Cited by 1,258 · see citing works
Self-citation
BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
Nam, K. H., & Li, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00814-0 · Cited by 1,217 · see citing works
Coordinated regulation of Arabidopsis thaliana development by light and gibberellins
Feng, S., Martínez, C., Gusmaroli, G., Wang, Y., Zhou, J., Wang, F., Chen, L., Yu, L., Iglesias‐Pedraz, J. M., Kircher, S., et al. (2008) · Nature · doi:10.1038/nature06448 · Cited by 1,118 · see citing works
NINJA connects the co-repressor TOPLESS to jasmonate signalling
Pauwels, L., Barbero, G. F., Geerinck, J., Tilleman, S., Grunewald, W., Pérez, A. C., Chico, J. M., Bossche, R. V., Sewell, J. A., Gil, E., et al. (2010) · Nature · doi:10.1038/nature08854 · Cited by 1,022 · see citing works
Direct control of shoot meristem activity by a cytokinin-activating enzyme
Kurakawa, T., Ueda, N., Maekawa, M., Kobayashi, K., Kojima, M., Nagato, Y., Sakakibara, H., & Kyozuka, J. (2007) · Nature · doi:10.1038/nature05504 · Cited by 998 · see citing works
A Genetic Framework for the Control of Cell Division and Differentiation in the Root Meristem
Ioio, R. D., Nakamura, K., Moubayidin, L., et al. (2008) · Science · doi:10.1126/science.1164147 · Cited by 944 · see citing works
Role of phytohormones in insect-specific plant reactions
Erb, M., Meldau, S., & Howe, G. A. (2012) · Trends in Plant Science · doi:10.1016/j.tplants.2012.01.003 · Cited by 917 · see citing works
Self-citation
The multifaceted role of ABA in disease resistance
Ton, J., Flors, V., & Mauch‐Mani, B. (2009) · Trends in Plant Science · doi:10.1016/j.tplants.2009.03.006 · Cited by 914 · see citing works
Auxin transport is sufficient to generate a maximum and gradient guiding root growth
Grieneisen, V. A., Xu, J., Marée, A. F. M., Hogeweg, P., & Scheres, B. (2007) · Nature · doi:10.1038/nature06215 · Cited by 893 · see citing works
Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade
Yang, D., Yao, J., Mei, C.-S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201616109 · Cited by 876 · see citing works
Genetic Characterization and Functional Analysis of the GID1 Gibberellin Receptors in Arabidopsis
Griffiths, J., Murase, K., Rieu, I., et al. (2006) · The Plant Cell · doi:10.1105/tpc.106.047415 · Cited by 853 · see citing works
COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine
Katsir, L., Schilmiller, A. L., Staswick, P., He, S. Y., & Howe, G. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802332105 · Cited by 816 · see citing works
Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation
Nagpal, P., Ellis, C., Weber, H. H., Ploense, S. E., Barkawi, L. S., Guilfoyle, T. J., Hagen, G., Alonso, J. M., Cohen, J. D., Farmer, E. E., et al. (2005) · Development · doi:10.1242/dev.01955 · Cited by 757 · see citing works
Adaptive Patterns in Alkaloid Physiology
McKey, D. (1974) · The American Naturalist · doi:10.1086/282909 · Cited by 750 · see citing works
KNOX Action in Arabidopsis Is Mediated by Coordinate Regulation of Cytokinin and Gibberellin Activities
Jasinski, S., Piazza, P., Craft, J., Hay, A., Woolley, L., Rieu, I., Phillips, A., Hedden, P., & Tsiantis, M. (2005) · Current Biology · doi:10.1016/j.cub.2005.07.023 · Cited by 749 · see citing works
DELLAs Control Plant Immune Responses by Modulating the Balance of Jasmonic Acid and Salicylic Acid Signaling
Navarro, L., Bari, R. P., Achard, P., Lisón, P., Nemri, A., Harberd, N. P., & Jones, J. D. G. (2008) · Current Biology · doi:10.1016/j.cub.2008.03.060 · Cited by 727 · see citing works
Arabidopsis MYC2 Interacts with DELLA Proteins in Regulating Sesquiterpene Synthase Gene Expression
Hong, G., Xue, X., Mao, Y., Wang, L.-J., & Chen, X. (2012) · The Plant Cell · doi:10.1105/tpc.112.098749 · Cited by 679 · see citing works
The control of developmental phase transitions in plants
Huijser, P., & Schmid, M. (2011) · Development · doi:10.1242/dev.063511 · Cited by 676 · see citing works
Sites and homeostatic control of auxin biosynthesis in Arabidopsis during vegetative growth
Ljung, K., Bhalerao, R. P., & Sandberg, G. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.01173.x · Cited by 653 · see citing works
Brassinosteroid Signal Transduction from Receptor Kinases to Transcription Factors
Kim, T., & Wang, Z. (2010) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.092057 · Cited by 650 · see citing works
Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apexPreprint
Swarup, R., Friml, J., Marchant, A., Ljung, K., Sandberg, G., Palme, K. J., & Bennett, M. J. (2001) · Genes & Development · doi:10.1101/gad.210501 · Cited by 645 · see citing works
Histidine Kinase Homologs That Act as Cytokinin Receptors Possess Overlapping Functions in the Regulation of Shoot and Root Growth in Arabidopsis
Nishimura, C., Ohashi, Y., Sato, S., Kato, T., Tabata, S., & Ueguchi, C. (2004) · The Plant Cell · doi:10.1105/tpc.021477 · Cited by 629 · see citing works
Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana : A factor of potential importance for auxin–cytokinin-regulated development
Nordström, A., Tarkowski, P., Tarkowska, D., Norbaek, R., Åstot, C., Dolezal, K., & Sandberg, G. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402504101 · Cited by 574 · see citing works
Arabidopsis KNOXI Proteins Activate Cytokinin Biosynthesis
Yanai, O., Shani, E., Doležal, K., Tarkowski, P., Sablowski, R. W. M., Sandberg, G., Samach, A., & Ori, N. (2005) · Current Biology · doi:10.1016/j.cub.2005.07.060 · Cited by 550 · see citing works
The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterningPreprint
Hamann, T., Benková, E., Bäurle, I., Kientz, M., & Jürgens, G. (2002) · Genes & Development · doi:10.1101/gad.229402 · Cited by 545 · see citing works
Convergent Evolution in Plant Specialized Metabolism
Pichersky, E., & Lewinsohn, E. (2011) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103814 · Cited by 523 · see citing works
Brassinosteroids control meristem size by promoting cell cycle progression in Arabidopsis roots
González‐García, M. P., Vilarrasa‐Blasi, J., Zhiponova, M., Divol, F., Mora‐García, S., Russinova, E., & Caño‐Delgado, A. I. (2011) · Development · doi:10.1242/dev.057331 · Cited by 522 · see citing works
Transcriptional machineries in jasmonate-elicited plant secondary metabolism
Geyter, N. D., Gholami, A., Goormachtig, S., & Goossens, A. (2012) · Trends in Plant Science · doi:10.1016/j.tplants.2012.03.001 · Cited by 519 · see citing works
Molecular Interactions between the Specialist Herbivore Manduca sexta (Lepidoptera, Sphingidae) and Its Natural Host Nicotiana attenuata . III. Fatty Acid-Amino Acid Conjugates in Herbivore Oral Secretions Are Necessary and Sufficient for Herbivore-Specific Plant Responses
Halitschke, R., Schittko, U., Pohnert, G., Boland, W., & Baldwin, I. T. (2001) · PLANT PHYSIOLOGY · doi:10.1104/pp.125.2.711 · Cited by 513 · see citing works
Self-citation
TOPLESS Regulates Apical Embryonic Fate in Arabidopsis
Long, J. A., Ohno, C. K., Smith, Z. R., & Meyerowitz, E. M. (2006) · Science · doi:10.1126/science.1123841 · Cited by 505 · see citing works
An Auxin Gradient and Maximum in the Arabidopsis Root Apex Shown by High-Resolution Cell-Specific Analysis of IAA Distribution and Synthesis
Petersson, S. V., Johansson, A. I., Kowalczyk, M., Makoveychuk, A., Wang, J. Y., Möritz, T., Grebe, M., Benfey, P. N., Sandberg, G., & Ljung, K. (2009) · The Plant Cell · doi:10.1105/tpc.109.066480 · Cited by 496 · see citing works
The Cytokinin-Activated Transcription Factor ARR2 Promotes Plant Immunity via TGA3/NPR1-Dependent Salicylic Acid Signaling in Arabidopsis
Choi, J., Huh, S. U., Kojima, M., Sakakibara, H., Paek, K.-H., & Hwang, I. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.07.011 · Cited by 470 · see citing works
An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack.
Howe, G. A., Lightner, J. E., Browse, J., & Ryan, C. A. (1996) · The Plant Cell · doi:10.1105/tpc.8.11.2067 · Cited by 456 · see citing works
Molecular Interactions of a Soluble Gibberellin Receptor, GID1, with a Rice DELLA Protein, SLR1, and Gibberellin
Ueguchi‐Tanaka, M., Nakajima, M., Katoh, E., et al. (2007) · The Plant Cell · doi:10.1105/tpc.106.043729 · Cited by 449 · see citing works
Gibberellin Acts through Jasmonate to Control the Expression of MYB21, MYB24, and MYB57 to Promote Stamen Filament Growth in Arabidopsis
Cheng, H. S., Song, S., Xiao, L., et al. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000440 · Cited by 443 · see citing works
Interactions among PIN-FORMED and P-Glycoprotein Auxin Transporters in Arabidopsis
Blakeslee, J. J., Bandyopadhyay, A., Lee, O. R., Mravec, J., Titapiwatanakun, B., Sauer, M., Makam, S. N., Cheng, Y., Bouchard, R., Adamec, J., et al. (2007) · The Plant Cell · doi:10.1105/tpc.106.040782 · Cited by 434 · see citing works
A Molecular Framework for Plant Regeneration
Xu, J., Hofhuis, H. F., Heidstra, R., Sauer, M., Friml, J., & Scheres, B. (2006) · Science · doi:10.1126/science.1121790 · Cited by 391 · see citing works
The auxin-insensitive bodenlos mutation affects primary root formation and apical-basal patterning in the Arabidopsis embryo
Hamann, T., Mayer, U., & Jürgens, G. (1999) · Development · doi:10.1242/dev.126.7.1387 · Cited by 386 · see citing works
Gibberellin-GID1-DELLA: A Pivotal Regulatory Module for Plant Growth and Development
Sun, T. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.161554 · Cited by 386 · see citing works
Apical dominance
Cline, M. G. (1991) · The Botanical Review · doi:10.1007/bf02858771 · Cited by 380 · see citing works
Studies on the Growth Hormone of Plants: III. The Inhibiting Action of the Growth Substance on Bud Development
Thimann, K. V., & Skoog, F. (1933) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.19.7.714 · Cited by 380 · see citing works
Brassinosteroid perception in the epidermis controls root meristem size
Hacham, Y., Holland, N., Butterfield, C. N., Úbeda-Tomás, S., Bennett, M. J., Chory, J., & Savaldi‐Goldstein, S. (2011) · Development · doi:10.1242/dev.061804 · Cited by 375 · see citing works
SHOOT BRANCHING
McSteen, P., & Leyser, O. (2005) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.56.032604.144122 · Cited by 356 · see citing works
Antisense LOX expression increases herbivore performance by decreasing defense responses and inhibiting growth‐related transcriptional reorganization in Nicotiana attenuata
Halitschke, R., & Baldwin, I. T. (2003) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01921.x · Cited by 342 · see citing works
Self-citation
Quantification, correlations and manipulations of wound-induced changes in jasmonic acid and nicotine in Nicotiana sylvestris
Baldwin, I. T., Zhang, Z., Diab, N., Ohnmeiss, T. E., McCLOUD, E. S., Lynds, G. Y., & Schmelz, E. A. (1997) · Planta · doi:10.1007/s004250050082 · Cited by 311 · see citing works
Self-citation
Gene expression and glucosinolate accumulation in Arabidopsis thaliana in response to generalist and specialist herbivores of different feeding guilds and the role of defense signaling pathways
Mewis, I., Tokuhisa, J. G., Schultz, J. C., Appel, H. M., Ulrichs, C., & Gershenzon, J. (2006) · Phytochemistry · doi:10.1016/j.phytochem.2006.09.004 · Cited by 305 · see citing works
Jasmonates: Structural Requirements for Lipid-Derived Signals Active in Plant Stress Responses and Development
Wasternack, C. H., & Kombrink, E. (2009) · ACS Chemical Biology · doi:10.1021/cb900269u · Cited by 278 · see citing works
Disruption of OPR7 and OPR8 Reveals the Versatile Functions of Jasmonic Acid in Maize Development and Defense
Yan, Y., Christensen, S. A., Isakeit, T., Engelberth, J., Meeley, R. B., Hayward, A., Emery, R. J. N., & Kolomiets, M. V. (2012) · The Plant Cell · doi:10.1105/tpc.111.094151 · Cited by 270 · see citing works
Ontogeny Constrains Systemic Protease Inhibitor Response in Nicotiana attenuata
van Dam, N. M., Horn, M., Mareš, M., & Baldwin, I. T. (2001) · Journal of Chemical Ecology · doi:10.1023/a:1010341022761 · Cited by 267 · see citing works
Self-citation
An Arabidopsis Mutant Defective in Jasmonate Response Is Allelic to the Auxin-Signaling Mutant axr1
Tiryaki, İ., & Staswick, P. (2002) · PLANT PHYSIOLOGY · doi:10.1104/pp.005272 · Cited by 266 · see citing works
Gene networks controlling the initiation of flower development
Wellmer, F., & Riechmann, J. L. (2010) · Trends in Genetics · doi:10.1016/j.tig.2010.09.001 · Cited by 261 · see citing works
R2R3-NaMYB8 Regulates the Accumulation of Phenylpropanoid-Polyamine Conjugates, Which Are Essential for Local and Systemic Defense against Insect Herbivores in Nicotiana attenuata
Kaur, H., Heinzel, N., Schöttner, M., Baldwin, I. T., & Gális, I. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.151738 · Cited by 254 · see citing works
Self-citation
Induction and detoxification of maize 1,4‐benzoxazin‐3‐ones by insect herbivores
Glauser, G., Marti, G., Villard, N., et al. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04740.x · Cited by 249 · see citing works
Can optimal defence theory be used to predict the distribution of plant chemical defences?
McCall, A. C., & Fordyce, J. A. (2010) · Journal of Ecology · doi:10.1111/j.1365-2745.2010.01693.x · Cited by 249 · see citing works
Benzoic acid glucosinolate esters and other glucosinolates from Arabidopsis thaliana
Reichelt, M., Brown, P. D., Schneider, B., et al. (2002) · Phytochemistry · doi:10.1016/s0031-9422(02)00014-6 · Cited by 248 · see citing works
Manipulation of Endogenous Trypsin Proteinase Inhibitor Production inNicotiana attenuataDemonstrates Their Function as Antiherbivore Defenses
Zavala, J. A., Patankar, A. G., Gase, K., Hui, D., & Baldwin, I. T. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.103.035634 · Cited by 247 · see citing works
Self-citation
Co(i)‐ordinating defenses: NaCOI1 mediates herbivore‐ induced resistance in Nicotiana attenuata and reveals the role of herbivore movement in avoiding defenses
Paschold, A., Halitschke, R., & Baldwin, I. T. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03119.x · Cited by 239 · see citing works
Self-citation
Methyl Jasmonate Application Induces Increased Densities of Glandular Trichomes on Tomato, Lycopersicon esculentum
Boughton, A. J., Hoover, K., & Felton, G. W. (2005) · Journal of Chemical Ecology · doi:10.1007/s10886-005-6228-7 · Cited by 238 · see citing works
Belowground Herbivory and Plant Defenses
van Dam, N. M. (2009) · Annual Review of Ecology Evolution and Systematics · doi:10.1146/annurev.ecolsys.110308.120314 · Cited by 226 · see citing works
Regulation of Root Greening by Light and Auxin/Cytokinin Signaling in Arabidopsis
Kobayashi, K., Baba, S., Obayashi, T., Sato, M., Toyooka, K., Keränen, M., Aro, E., Fukaki, H., Ohta, H., Sugimoto, K., et al. (2012) · The Plant Cell · doi:10.1105/tpc.111.092254 · Cited by 223 · see citing works
Auxin Acts in Xylem-Associated or Medullary Cells to Mediate Apical Dominance
Booker, J., Chatfield, S. P., & Leyser, O. (2003) · The Plant Cell · doi:10.1105/tpc.007542 · Cited by 221 · see citing works
Response of cytokinin concentration in the xylem exudate of bean (Phaseolus vulgaris L.) plants to decapitation and auxin treatment, and relationship to apical dominance
Bangerth, F. (1994) · Planta · doi:10.1007/bf00197546 · Cited by 220 · see citing works
Cytokinins Mediate Resistance againstPseudomonas syringaein Tobacco through Increased Antimicrobial Phytoalexin Synthesis Independent of Salicylic Acid Signaling
Großkinsky, D. K., Naseem, M., Abdelmohsen, U. R., Plickert, N., Engelke, T., Griebel, T., Zeier, J., Novák, O., Strnad, M., Pfeifhofer, H. W., et al. (2011) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.182931 · Cited by 211 · see citing works
Jasmonic acid control of GLABRA3 links inducible defense and trichome patterning in Arabidopsis
Yoshida, Y., Sano, R., Wada, T., Takabayashi, J., & Okada, K. (2009) · Development · doi:10.1242/dev.030585 · Cited by 208 · see citing works
OPTIMAL DEFENSE THEORY PREDICTS THE ONTOGENY OF AN INDUCED NICOTINE DEFENSE
Ohnmeiss, T. E., & Baldwin, I. T. (2000) · Ecology · doi:10.1890/0012-9658(2000)081[1765:odtpto]2.0.co;2 · Cited by 201 · see citing works
Self-citation
Hormone signaling in plant development
Durbak, A. R., Yao, H., & McSteen, P. (2012) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2011.12.004 · Cited by 200 · see citing works
Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin
Grunewald, W., Vanholme, B., Pauwels, L., Plovie, E. R., Inzé, D., Gheysen, G., & Goossens, A. (2009) · EMBO Reports · doi:10.1038/embor.2009.103 · Cited by 199 · see citing works
Jasmonate and ppHsystemin Regulate Key Malonylation Steps in the Biosynthesis of 17-Hydroxygeranyllinalool Diterpene Glycosides, an Abundant and Effective Direct Defense against Herbivores inNicotiana attenuata
Heiling, S., Schuman, M. C., Schöttner, M., Mukerjee, P., Berger, B., Schneider, B., Jassbi, A. R., & Baldwin, I. T. (2010) · The Plant Cell · doi:10.1105/tpc.109.071449 · Cited by 178 · see citing works
Self-citation
A specialist root herbivore exploits defensive metabolites to locate nutritious tissues
Robert, C. A. M., Veyrat, N., Glauser, G., Marti, G., Doyen, G. R., Villard, N., Gaillard, M. D. P., Köllner, T. G., Giron, D., Body, M. J. A., et al. (2011) · Ecology Letters · doi:10.1111/j.1461-0248.2011.01708.x · Cited by 176 · see citing works
Self-citation
MYB8 Controls Inducible Phenolamide Levels by Activating Three Novel Hydroxycinnamoyl-Coenzyme A:Polyamine Transferases in Nicotiana attenuata
Onkokesung, N., Gaquerel, E., Kotkar, H. M., Kaur, H., Baldwin, I. T., & Gális, I. (2011) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.187229 · Cited by 172 · see citing works
Self-citation
Variation of DIMBOA and related compounds content in relation to the age and plant organ in maize
Cambier, V., Hance, T., & de Hoffmann, E. (2000) · Phytochemistry · doi:10.1016/s0031-9422(99)00498-7 · Cited by 170 · see citing works
The Tomato odorless-2 Mutant Is Defective in Trichome-Based Production of Diverse Specialized Metabolites and Broad-Spectrum Resistance to Insect Herbivores
Kang, J.-H., Liu, G., Shi, F., Jones, A. D., Beaudry, R. M., & Howe, G. A. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.160192 · Cited by 168 · see citing works
Transport of exogenous auxin in two-branched dwarf pea seedlings (Pisum sativum L.): Some implications for polarity and apical dominance
Morris, D. A. (1977) · Planta · doi:10.1007/bf00387930 · Cited by 165 · see citing works
ARR1 Directly Activates Cytokinin Response Genes that Encode Proteins with Diverse Regulatory Functions
Taniguchi, M., Sasaki, N., Tsuge, T., Aoyama, T., & Oka, A. (2007) · Plant and Cell Physiology · doi:10.1093/pcp/pcl063 · Cited by 160 · see citing works
Brassinosteroids interact negatively with jasmonates in the formation of anti-herbivory traits in tomato
Campos, M. L., de Almeida, M., Rossi, M. L., Martinelli, A. P., Litholdo, C. G., Figueira, A., Rampelotti-Ferreira, F. T., Vendramim, J. D., Benedito, V. A., & Peres, L. E. P. (2009) · Journal of Experimental Botany · doi:10.1093/jxb/erp270 · Cited by 157 · see citing works
Inducible Nicotine Production in Native Nicotiana as an Example of Adaptive Phenotypic Plasticity
Baldwin, I. T. (1999) · Journal of Chemical Ecology · doi:10.1023/a:1020880931488 · Cited by 154 · see citing works
Self-citation
Brassinosteroids Control the Proliferation of Leaf Cells of Arabidopsis thaliana
Nakaya, M., Tsukaya, H., Murakami, N., et al. (2002) · Plant and Cell Physiology · doi:10.1093/pcp/pcf024 · Cited by 150 · see citing works
Transcriptional Diversification and Functional Conservation between DELLA Proteins in Arabidopsis
Gallego‐Bartolomé, J., Minguet, E. G., Marin, J. A., Prat, S., Blázquez, M. A., & Alabadı́, D. (2010) · Molecular Biology and Evolution · doi:10.1093/molbev/msq012 · Cited by 148 · see citing works
Temporal and spatial variation in cyanogenic glycosides in Eucalyptus cladocalyx
Gleadow, R. M., & Woodrow, I. E. (2000) · Tree Physiology · doi:10.1093/treephys/20.9.591 · Cited by 128 · see citing works
Type‐A response regulators are required for proper root apical meristem function through post‐transcriptional regulation of PIN auxin efflux carriers
Zhang, W., To, J. P. C., Cheng, C., Schaller, G. E., & Kieber, J. J. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04668.x · Cited by 127 · see citing works
Brassinosteroid Enhances Jasmonate‐Induced Anthocyanin Accumulation in Arabidopsis Seedlings
Peng, Z., Han, C., Yuan, L., Zhang, K., Huang, H., & Ren, C. (2011) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2011.01042.x · Cited by 126 · see citing works
Transformation of shoots into roots inArabidopsisembryos mutant at theTOPLESSlocus
Long, J. A., Woody, S., Poethig, R. S., Meyerowitz, E. M., & Barton, M. K. (2002) · Development · doi:10.1242/dev.129.12.2797 · Cited by 120 · see citing works
A Leaky Mutation in DWARF4 Reveals an Antagonistic Role of Brassinosteroid in the Inhibition of Root Growth by Jasmonate in Arabidopsis
Ren, C., Han, C., Peng, W., Huang, Y., Peng, Z., Xiong, X., Zhu, Q., Gao, B., & Xie, D. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.140202 · Cited by 115 · see citing works
Auxin-Cytokinin Interactions in Wild-Type and Transgenic Tobacco
Eklöf, S., Åstot, C., Blackwell, J., Möritz, T., Olsson, O., & Sandberg, G. (1997) · Plant and Cell Physiology · doi:10.1093/oxfordjournals.pcp.a029157 · Cited by 113 · see citing works
Silencing Geranylgeranyl Diphosphate Synthase inNicotiana attenuataDramatically Impairs Resistance to Tobacco Hornworm
Jassbi, A. R., Gase, K., Hettenhausen, C., Schmidt, A., & Baldwin, I. T. (2007) · PLANT PHYSIOLOGY · doi:10.1104/pp.107.108811 · Cited by 98 · see citing works
Self-citation
Early cytokinin response proteins and phosphoproteins of Arabidopsis thaliana identified by proteome and phosphoproteome profiling
Černý, M., Dyčka, F., Bobáľová, J., & Brzobohatý, B. (2010) · Journal of Experimental Botany · doi:10.1093/jxb/erq322 · Cited by 74 · see citing works
Mechanisms of Optimal Defense Patterns in Nicotiana attenuata: Flowering Attenuates Herbivory-elicited Ethylene and Jasmonate SignalingF
Diezel, C., Allmann, S., & Baldwin, I. T. (2011) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2011.01086.x · Cited by 74 · see citing works
Self-citation
NaJAZh Regulates a Subset of Defense Responses against Herbivores and Spontaneous Leaf Necrosis inNicotiana attenuataPlants
Oh, Y., Baldwin, I. T., & Gális, I. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.193771 · Cited by 74 · see citing works
Self-citation
Apical dominance and the levels of indole acetic acid in Phaseolus lateral buds
Hillman, J., Math, V. B., & Medlow, G. C. (1977) · Planta · doi:10.1007/bf00384970 · Cited by 56 · see citing works
Plasticity in allocation of nicotine to reproductive parts inNicotiana attenuata
Baldwin, I. T., & Karb, M. J. (1995) · Journal of Chemical Ecology · doi:10.1007/bf02033797 · Cited by 48 · see citing works
Self-citation
Ectopic expression of maize knotted1 results in the cytokinin-autotrophic growth of cultured tobacco tissues
Hewelt, A., Prinsen, E., Thomas, M., Onckelen, H. A. V., & Meins, F. (2000) · Planta · doi:10.1007/s004250050693 · Cited by 45 · see citing works
A Model Without a Mimic: Aristolochic Acids from the California Pipevine Swallowtail, Battus philenor hirsuta, and Its Host Plant, Aristolochia californica
Fordyce, J. A. (2000) · Journal of Chemical Ecology · doi:10.1023/a:1005588829864 · Cited by 40 · see citing works
Ethylene-regulated transcription and crosstalk with jasmonic acid
Shinshi, H. (2008) · Plant Science · doi:10.1016/j.plantsci.2008.03.017 · Cited by 39 · see citing works
Back to the past for pollination biology
Kessler, D., & Baldwin, I. T. (2011) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2011.03.023 · Cited by 22 · see citing works
Self-citation
Scopolamine in Brugmansia Suaveolens (Solanaceae): Defense, Allocation, Costs, and Induced Response
Alves, M. N., Sartoratto, A., & Trigo, J. R. (2007) · Journal of Chemical Ecology · doi:10.1007/s10886-006-9214-9
Environmental perception avenues: the interaction of cytokinin and environmental response pathways
ARGUESO, C. T., FERREIRA, F. J., & KIEBER, J. J. (2009) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2009.01940.x
Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana
Brown, P. D., Tokuhisa, J. G., Reichelt, M., & Gershenzon, J. (2003) · Phytochemistry · doi:10.1016/s0031-9422(02)00549-6
Changes in resource concentration and defence during leaf development in a tough-leaved (Nothofagus moorei) and soft-leaved (Toona ciliata) species
Brunt, C., Read, J., & Sanson, G. D. (2006) · Oecologia · doi:10.1007/s00442-006-0369-4
Selection of plastid- and nuclear-encoded reference genes to study the effect of altered endogenous cytokinin content on photosynthesis genes in Nicotiana tabacum
Cortleven, A., Remans, T., Brenner, W. G., & Valcke, R. (2009) · Photosynthesis Research · doi:10.1007/s11120-009-9470-y
Extreme differences in pyrrolizidine alkaloid levels between leaves of Cynoglossum officinale
van Dam, N. M., Verpoorte, R., & van der Meijden, E. (1994) · Phytochemistry · doi:10.1016/s0031-9422(00)89519-9
Cytokinins Determine Arabidopsis Root-Meristem Size by Controlling Cell Differentiation
Ioio, R. D., Linhares, F. S., Scacchi, E., Casamitjana-Martinez, E., Heidstra, R., Costantino, P., & Sabatini, S. (2007) · Current Biology · doi:10.1016/j.cub.2007.02.047
Cytokinin Primes Plant Responses to Wounding and Reduces Insect Performance
Dervinis, C., Frost, C. J., Lawrence, S. D., Novak, N. G., & Davis, J. M. (2010) · Journal of Plant Growth Regulation · doi:10.1007/s00344-009-9135-2
Hormonal input in plant meristems: A balancing act
Galinha, C., Bilsborough, G., & Tsiantis, M. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2009.09.007
Plants grow on brassinosteroids
Gudesblat, G. E., & Russinova, E. (2011) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2011.05.004
Distribution and concentration of total phenolics, condensed tannins, and nordihydroguaiaretic acid (NDGA) in creosotebush (Larrea tridentata)
Hyder, P. W., Fredrickson, E. L., Estell, R. E., Tellez, M., & Gibbens, R. P. (2002) · Biochemical Systematics and Ecology · doi:10.1016/s0305-1978(02)00050-9
Increased cytokinin levels in transgenic PSAG12–IPT tobacco plants have large direct and indirect effects on leaf senescence, photosynthesis and N partitioning
Jordi, W., Schapendonk, A., Davelaar, E., Stoopen, G. M., Pot, C. S., Visser, R. D., Rhijn, J. A. V., Gan, S., & Amasino, R. M. (2000) · Plant, Cell & Environment · doi:10.1046/j.1365-3040.2000.00544.x
Field Experiments with Transformed Plants Reveal the Sense of Floral Scents
Kessler, D., Gase, K., & Baldwin, I. T. (2008) · Science · doi:10.1126/science.1160072
Self-citation
Unpredictability of nectar nicotine promotes outcrossing by hummingbirds in Nicotiana attenuata
Kessler, D., Bhattacharya, S., Diezel, C., Rothe, E., Gase, K., Schöttner, M., & Baldwin, I. T. (2012) · The Plant Journal · doi:10.1111/j.1365-313x.2012.05008.x
Self-citation
Influence of nitrogen availability on shoot development in young peach trees [ Prunus persica (L.) Batsch]
Médiène, S., Pagès, L., Jordan, M.-O., Bot, J. L., & Adamowicz, S. (2002) · Trees · doi:10.1007/s00468-002-0204-4
Independently Silencing Two Photosynthetic Proteins in Nicotiana attenuata Has Different Effects on Herbivore Resistance
Mitra, S., & Baldwin, I. T. (2008) · Plant Physiology · doi:10.1104/pp.108.124354
Self-citation
Integrated Systems View on Networking by Hormones in Arabidopsis Immunity Reveals Multiple Crosstalk for Cytokinin
Naseem, M., Philippi, N., Hussain, A., Wangorsch, G., Ahmed, N., & Dandekar, T. (2012) · The Plant Cell · doi:10.1105/tpc.112.098335
Leaf Senescence Is Delayed in Tobacco Plants Expressing the Maize Homeobox Gene knotted1 under the Control of a Senescence-Activated Promoter
Ori, N., Juarez, M. T., Jackson, D., Yamaguchi, J., Banowetz, G. M., & Hake, S. (1999) · The Plant Cell · doi:10.2307/3870799
Altered cytokinin metabolism affects cytokinin, auxin, and abscisic acid contents in leaves and chloroplasts, and chloroplast ultrastructure in transgenic tobacco
Polanska, L., Vicankova, A., Novakova, M., Malbeck, J., Dobrev, P. I., Brzobohaty, B., Vankova, R., & Machackova, I. (2006) · Journal of Experimental Botany · doi:10.1093/jxb/erl235
Testing the optimal defence hypothesis for two indirect defences: extrafloral nectar and volatile organic compounds
Radhika, V., Kost, C., Bartram, S., Heil, M., & Boland, W. (2008) · Planta · doi:10.1007/s00425-008-0749-6
Ontogenetic and spatio-temporal patterns of induced volatiles in Glycine max in the light of the optimal defence hypothesis
Rostás, M., & Eggert, K. (2008) · Chemoecology · doi:10.1007/s00049-007-0390-z
Nitrogen economics of root foraging: Transitive closure of the nitrate–cytokinin relay and distinct systemic signaling for N supply vs. demand
Ruffel, S., Krouk, G., Ristova, D., Shasha, D., Birnbaum, K. D., & Coruzzi, G. M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108684108
Regulation by Cytokinins of Endogenous Levels of Jasmonic and Salicylic Acids in Mechanically Wounded Tobacco Plants
Sano, H., Seo, S., Koizumi, N., Niki, T., Iwamura, H., & Ohashi, Y. (1996) · Plant and Cell Physiology · doi:10.1093/oxfordjournals.pcp.a029011
Cytokinin-mediated insect resistance in Nicotiana plants transformed with the ipt gene
Smigocki, A., Neal, J. W., McCanna, I., & Douglass, L. (1993) · Plant Molecular Biology · doi:10.1007/bf00029008
Bypassing Transcription: A Shortcut in Cytokinin-Auxin Interactions
Stepanova, A. N., & Alonso, J. M. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.09.016
Induced Resistance in Agricultural Crops: Effects of Jasmonic Acid on Herbivory and Yield in Tomato Plants
Thaler, J. S. (1999) · Environmental Entomology · doi:10.1093/ee/28.1.30
GLUCOSINOLATES AND TRICHOMES TRACK TISSUE VALUE IN TWO SYMPATRIC MUSTARDS
Traw, M. B., & Feeny, P. (2008) · Ecology · doi:10.1890/07-0729.1
AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis
Vidaurre, D. P., Ploense, S., Krogan, N. T., & Berleth, T. (2007) · Development · doi:10.1242/dev.006759
Chapter 13 Adaptive Defense Responses to Pathogens and Insects
Walling, L. L. (2009) · Advances in Botanical Research · doi:10.1016/s0065-2296(09)51013-0
BAK1 regulates the accumulation of jasmonic acid and the levels of trypsin proteinase inhibitors in Nicotiana attenuata's responses to herbivory
Yang, D.-H., Hettenhausen, C., Baldwin, I. T., & Wu, J. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/erq298
Self-citation
Optimal defence, kin conflict and the distribution of furanocoumarins among offspring of wild parsnip
Zangerl, A. R., & Nitao, J. K. (1998) · Evolutionary Ecology · doi:10.1023/a:1006572805289
Cytokinin Stimulates Chloroplast Transcription in Detached Barley Leaves
Zubo, Y. O., Yamburenko, M. V., Selivankina, S. Y., Shakirova, F. M., Avalbaev, A. M., Kudryakova, N. V., Zubkova, N. K., Liere, K., Kulaeva, O. N., Kusnetsov, V. V., et al. (2008) · Plant Physiology · doi:10.1104/pp.108.122275

Flagged first, then by citations

Research works printed but not linked: 7

An CF, Mou ZL. 2011. Salicylic acid and its function in plant immunity. Journal of Integrative Plant Biology 53: 412 -428.
Argueso CT, Ferreira FJ, Epple P, et al. 2012. Two-component elements mediate interactions between cytokinin and salicylic acid in plant immunity. PloS Genetics 8: e1002448. http://dx.doi.org/10.1371/journal. pgen.1002448. · DOI
Baldwin IT, Onmeiss TE. 1993. Alkaloidal responses to damage in Nicotiana native to North America. Journal of Chemical Ecology 19: 1143-1153
Barrett SCH. 2010. Understanding plant reproductive diversity. Philosophical Transactions of the Royal Society. B: Biological Sciences 365: 99-109.
Del Bianco M, Kepinski S. 2011. Context, specificity, and self-organization in auxin response. Cold Spring Harbor Perspectives in Biology 3: a001578. http://dx.doi.org/10.1101/cshperspect.a001578. · DOI
He JX, Gendron JM, Yang YL, Li JM, Wang ZY. 2002. The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis. Proceedings of the National Academy of Sciences of the USA 99: 10185-10190.
Miller CO, Skoog F, Vonsaltza MH, Strong FM. 1955. Kinetin, a cell div- ision factor from deoxyribonucleic acid. Journal of the American Chemical Society 77: 1392-1392.

Sorted by citations

Jasmonates: Biosynthesis, perception, signal transduction and action in plant stress response, growth and development. An update to the 2007 review in Annals of Botany
Wasternack, C., & Hause, B. (2013) · Annals of Botany · doi:10.1093/aob/mct067 · Cited by 2,629 · see citing works
Plant Secondary Metabolites as Defenses, Regulators, and Primary Metabolites: The Blurred Functional Trichotomy
Erb, M., & Kliebenstein, D. J. (2020) · Plant Physiology · doi:10.1104/pp.20.00433 · Cited by 1,333 · see citing works
Self-citation
Light Regulation of Plant Defense
Ballaré, C. L. (2014) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050213-040145 · Cited by 555 · see citing works
Explaining intraspecific diversity in plant secondary metabolites in an ecological context
Moore, B. D., Andrew, R. L., Külheim, C., & Foley, W. J. (2013) · New Phytologist · doi:10.1111/nph.12526 · Cited by 536 · see citing works
Integrating circadian dynamics with physiological processes in plants
Greenham, K. M., & Mcclung, C. (2015) · Nature reviews genetics · doi:10.1038/nrg3976 · Cited by 437 · see citing works
Jasmonates: Multifunctional Roles in Stress Tolerance
Ahmad, P., Rasool, S., Gul, A., Sheikh, S. A., Akram, N. A., Ashraf, M., Kazi, A. M., & Gücel, S. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00813 · Cited by 386 · see citing works
“Both MAPKs played a differential role in regulating the plants’ growth-defense balance (Meldau et al., 2012).”
BackgroundInfluential
The Layers of Plant Responses to Insect Herbivores
Schuman, M. C., & Baldwin, I. T. (2015) · Annual Review of Entomology · doi:10.1146/annurev-ento-010715-023851 · Cited by 389 · see citing works
Self-citation
Late seed maturation: drying without dying
Leprince, O., Pellizzaro, A., Berriri, S., & Buitink, J. (2016) · Journal of Experimental Botany · doi:10.1093/jxb/erw363 · Cited by 334 · see citing works
“The optimal defence hypothesis proposes that under biotic threat, a plant will defend best those tissues or organs that contribute most to its fitness and/or exhibit a high probability of being attacked by pathogens (Meldau et al., 2012).”
Background
Jasmonate-Triggered Plant Immunity
Campos, M. L., Kang, J. H., & Howe, G. A. (2014) · Journal of Chemical Ecology · doi:10.1007/s10886-014-0468-3 · Cited by 366 · see citing works
“…its interaction with other signaling pathways, and the function of JA in developmental processes (Ballaré 2011; Browse 2009; Huot et al. 2014 Kazan and Manners 2008, 2012; Kombrink 2012; Meldau et al. 2012; Pauwels and Goossens 2011; Robert- Seilaniantz et al. 2011; Wasternack and Hause 2013).”
Action of jasmonates in plant stress responses and development — Applied aspects
Wasternack, C. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.09.009 · Cited by 339 · see citing works
Plant secondary metabolites as defenses, regulators and primary metabolites- The blurred functional trichotomyPreprint
Erb, M., & Kliebenstein, D. J. (2020) · Plant Physiology · doi:10.31219/osf.io/6ba7r · Cited by 51 · see citing works
“Ecological theory explains this within-plant variation using resource constraints, allocation costs, and variation in herbivore pressure (McKey, 1974; van Dam, 2009; Meldau et al., 2012; Schuman and Baldwin, 2016; Barton and Boege, 2017).”
BackgroundSelf-citation
Green leaf volatiles: biosynthesis, biological functions and their applications in biotechnology
Hassan, M. N. U., Zainal, Z., & Ismail, I. (2015) · Plant Biotechnology Journal · doi:10.1111/pbi.12368 · Cited by 192 · see citing works
“Recent studies have elucidated the role of insect oral secretions in promoting wound-induced responses (Erb et al., 2012; Meldau et al., 2012).”
Background
Methyl Jasmonate Regulates Antioxidant Defense and Suppresses Arsenic Uptake in Brassica napus L.
Farooq, M. A., Gill, R. A., Islam, F., Ali, B., Liu, H., Xu, J., He, S.-P., & Zhou, W. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00468 · Cited by 219 · see citing works
“These results proposed that MJ signaling efficiently uncouples the growth from photosynthesis and helps to redirect the biosynthetic capacity from growth to defense (Meldau et al., 2012).”
Background
Temporal Dynamics of Growth and Photosynthesis Suppression in Response to Jasmonate Signaling
Attaran, E., Major, I. T., Cruz, J. A., Rosa, B. A., Koo, A. J., Chen, J., Kramer, D., He, S. Y., & Howe, G. A. (2014) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.239004 · Cited by 208 · see citing works
“…consisting of the CORONATINE INSENSITIVE1 (COI1) F-box protein and JASMONATE ZIM DOMAIN (JAZ) transcriptional repressor proteins (Xie et al., 1998; Chini et al., 2007; Thines et al., 2007; Yan et al., 2007; Katsir et al., 2008; Melotto et al., 2008; Fonseca et al., 2009; Sheard et al., 2010).”
Background
Plant-insect interactions under bacterial influence: ecological implications and underlying mechanisms
Sugio, A., Dubreuil, G., Giron, D., & Simon, J.-C. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru435 · Cited by 214 · see citing works
Leaf-herbivore attack reduces carbon reserves and regrowth from the roots via jasmonate and auxin signaling.
Machado, R. A. R., Ferrieri, A. P., Robert, C., Glauser, G., Kallenbach, M., Baldwin, I., & Erb, M. (2013) · New Phytologist · doi:10.1111/nph.12438 · Cited by 166
Self-citation
Induction of Systemic Resistance against Insect Herbivores in Plants by Beneficial Soil Microbes
Rashid, M. H.-O., & Chung, Y. R. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01816 · Cited by 190 · see citing works
“Other hormones, such as auxin, ET, CK, ABA and GA, can also modulate signaling pathways during interactions between plants and biotic factors, pathogens and insects (Robert-Seilaniantz et al., 2011; Meldau et al., 2012; Pieterse et al., 2012; Giron et al., 2013).”
Background
The growth–defense pivot: crisis management in plants mediated by LRR-RK surface receptors
Belkhadir, Y., Yang, L., Hetzel, J., Dangl, J. L., & Chory, J. (2014) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2014.06.006 · Cited by 162 · see citing works
“Responding to living organisms like pathogens requires temporary modulation of investments made into growth [9].”
Influential
The nexus between growth and defence signalling: auxin and cytokinin modulate plant immune response pathways
Naseem, M., Kaltdorf, M., & Dandekar, T. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv297 · Cited by 163 · see citing works
Future directions in the ontogeny of plant defence: understanding the evolutionary causes and consequences
Barton, K. E., & Boege, K. (2017) · Ecology Letters · doi:10.1111/ele.12744 · Cited by 144 · see citing works
Which leaf mechanical traits correlate with insect herbivory among feeding guilds?
Caldwell, E., Read, J., & Sanson, G. D. (2015) · Annals of Botany · doi:10.1093/aob/mcv178 · Cited by 140 · see citing works
“Insect herbivores often prefer young leaves, which are typically softer, often with higher nutrient concentrations, but sometimes higher levels of chemical defence (Coley, 1983; Lowman and Box, 1983; Meldau et al., 2012).”
Background
From local to global: CDPKs in systemic defense signaling upon microbial and herbivore attack.
Romeis, T., & Herde, M. (2014) · Current opinion in plant biology · doi:10.1016/j.pbi.2014.03.002 · Cited by 132
Induced Jasmonate Signaling Leads to Contrasting Effects on Root Damage and Herbivore Performance
Lu, J., Robert, C. A. M., Riemann, M., Cosme, M., Mène‐Saffrané, L., Codina, J. M., Stout, M. J., Lou, Y., Gershenzon, J., & Erb, M. (2015) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.252700 · Cited by 141 · see citing works
Self-citation
How fungi defend themselves against microbial competitors and animal predators
Künzler, M. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007184 · Cited by 144 · see citing works
Transport of defense compounds from source to sink: lessons learned from glucosinolates.
Jørgensen, M. E., Nour-Eldin, H., & Halkier, B. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2015.04.006 · Cited by 114
A perspective on inter-kingdom signaling in plant–beneficial microbe interactions
Rosier, A., Bishnoi, U., Lakshmanan, V., Sherrier, D. J., & Bais, H. P. (2016) · Plant Molecular Biology · doi:10.1007/s11103-016-0433-3 · Cited by 124 · see citing works
“However, opportunistic interactions may become mutualistic and help plants to adapt to different biotic and abiotic stresses (Rudrappa et al. 2008; Lakshmanan et al. 2012; Meldau et al. 2012; Santhanam et al. 2014) (Fig.”
The role of glucosinolates and the jasmonic acid pathway in resistance of Arabidopsis thaliana against molluskan herbivores
Falk, K. L., Kästner, J., Bodenhausen, N., Schramm, K., Paetz, C., Vassão, D. G., Reichelt, M., von Knorre, D., Bergelson, J., Erb, M., et al. (2014) · Molecular Ecology · doi:10.1111/mec.12610 · Cited by 90
Self-citation
Induction of antibacterial proteins and peptides in the coprophilous mushroom Coprinopsis cinerea in response to bacteria
Kombrink, A., Tayyrov, A., Essig, A., Stöckli, M., Micheller, S., Hintze, J., van Heuvel, Y., Dürig, N., Lin, C., Kallio, P. T., et al. (2018) · The ISME Journal · doi:10.1038/s41396-018-0293-8 · Cited by 94 · see citing works
Phylogenetic correlations among chemical and physical plant defenses change with ontogeny.
Kariñho-Betancourt, E., Agrawal, A., Halitschke, R., & Núñez-Farfán, J. (2015) · New Phytologist · doi:10.1111/nph.13300 · Cited by 79 · see citing works
How Jasmonates Earned their Laurels: Past and Present
Wasternack, C. (2015) · Journal of Plant Growth Regulation · doi:10.1007/s00344-015-9526-5 · Cited by 93 · see citing works
“Designed by the author with data from Web of Science J Plant Growth Regul (2015) 34:761–794 767 and Baldwin 2004; Howe and Jander 2008; Kennedy 2003; Koo and Howe 2009; Matsui 2006; Meldau and others 2012; Savchenko and others 2014; Walling 2000; Wasternack and Hause 2002).”
Method
Leaf-Miners Co-opt Microorganisms to Enhance their Nutritional Environment
Body, M. J. A., Kaiser, W., Dubreuil, G., Casas, J., & Giron, D. (2013) · Journal of Chemical Ecology · doi:10.1007/s10886-013-0307-y · Cited by 76
“Cytokinins (CKs) are plant hormones that play a key role in plant morphology, plant defense, leaf senescence, and source-sink relationships (Erb et al. 2012; Meldau et al. 2012; Mok and Mok 2001; Sakakibara 2006).”
Background
Organ-specific regulation of growth-defense tradeoffs by plants.
Smakowska, E., Kong, J.-X., Busch, W., & Belkhadir, Y. (2016) · Current opinion in plant biology · doi:10.1016/j.pbi.2015.12.005 · Cited by 71
Effects of methyl jasmonate on plant growth and leaf properties
Cui, L., Wang, P., Menzies, N., Lombi, E., & Kopittke, P. (2018) · doi:10.1002/jpln.201700373 · Cited by 70
Root chemical traits and their roles in belowground biotic interactions
Tsunoda, T., & van Dam, N. (2017) · doi:10.1016/j.pedobi.2017.05.007 · Cited by 68
Herbivore feeding preference corroborates optimal defense theory for specialized metabolites within plants
Hunziker, P., Lambertz, S., Weber, K., Crocoll, C., Halkier, B., & Schulz, A. (2021) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2111977118 · Cited by 67
Jasmonate-dependent induction of polyphenol oxidase activity in tomato foliage is important for defense against Spodoptera exigua but not against Manduca sexta
Bosch, M., Berger, S., Schaller, A., & Stintzi, A. (2014) · BMC Plant Biology · doi:10.1186/s12870-014-0257-8 · Cited by 67
From trade-off to synergy: how nutrient status modulates plant resistance to herbivorous insects?
Li, Z., Tan, J., Yao, N., & Xie, R. (2024) · Advanced Biotechnology · doi:10.1007/s44307-024-00045-5 · Cited by 67 · see citing works
Cis- and trans-zeatin differentially modulate plant immunity
Grosskinsky, D. K., Edelsbrunner, K., Pfeifhofer, H., van der Graaff, E., & Roitsch, T. (2013) · Plant Signalling & Behavior · doi:10.4161/psb.24798 · Cited by 60
“Additionally, natural variations of CK content and spectrum within one plant may control the defense status of specific organs and thus contribute to the regulation of optimal defense patterns.(20)”
Background
Temporal dynamics of bacterial communities during seed development and maturation
Chesneau, G., Torres‐Cortés, G., Briand, M., Darrasse, A., Préveaux, A., Marais, C., Jacques, M., Shade, A. L., & Barret, M. (2020) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiaa190 · Cited by 68 · see citing works
Cytokinin-Induced Phenotypes in Plant-Insect Interactions: Learning from the Bacterial World
Giron, D., & Glévarec, G. (2014) · Journal of Chemical Ecology · doi:10.1007/s10886-014-0466-5 · Cited by 56
Phosphate‐induced resistance to pathogen infection in Arabidopsis
Val‐Torregrosa, B., Bundó, M., Martín‐Cardoso, H., Bach‐Pages, M., Chiou, T., Flors, V., & Segundo, B. S. (2022) · The Plant Journal · doi:10.1111/tpj.15680 · Cited by 64 · see citing works
The plant cell wall integrity maintenance mechanism – A case study of a cell wall plasma membrane signaling network
Hamann, T. (2014) · Phytochemistry · doi:10.1016/j.phytochem.2014.09.019 · Cited by 65 · see citing works
“…insights into the mechanisms translating combinations of different stimuli or stresses into distinct response patterns have illustrated how a plant can perceive different stimuli simultaneously, and integrate the resulting signals to generate quantitative, adaptive responses (Meldau et al., 2012).”
Background
Regulation of Abiotic and Biotic Stress Responses by Plant Hormones
Grosskinsky, D. K., van der Graaff, E., & Roitsch, T. (2016) · doi:10.1002/9781118867716.ch7 · Cited by 52 · see citing works
Antioxidant status of medicinal and aromatic plants under the influence of growth-promoting rhizobacteria and osmotic stress
Chiappero, J., Cappellari, L. D. R., Palermo, T. B., Giordano, W., Khan, N., & Banchio, E. (2021) · doi:10.1016/j.indcrop.2021.113541 · Cited by 50
Root and shoot glucosinolate allocation patterns follow optimal defence allocation theory
Tsunoda, T., Krosse, S., & van Dam, N. (2017) · doi:10.1111/1365-2745.12793 · Cited by 49
Growth–defence balance in grass biomass production: the role of jasmonates
Shyu, C., & Brutnell, T. P. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv011 · Cited by 58 · see citing works
Anthropogenic increase in carbon dioxide modifies plant-insect interactions
Zavala, J. A., Gog, L., & Giacometti, R. (2016) · Annals of Applied Biology · doi:10.1111/aab.12319 · Cited by 50 · see citing works
Induced defense mechanisms in an aquatic angiosperm to insect herbivory
Fornoff, F., & Gross, E. (2014) · Oecologia · doi:10.1007/s00442-013-2880-8 · Cited by 44
Plants protect themselves from herbivores by optimizing the distribution of chemical defenses
Gershenzon, J., & Ullah, C. (2022) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2120277119 · Cited by 43
Correlation of Phenylalanine ammonia lyase (PAL) and Tyrosine ammonia lyase (TAL) activities to phenolics and curcuminoid content in ginger and its wild congener, Zingiber zerumbet following Pythium myriotylum infection
Ganapathy, G., Keerthi, D., Nair, R. A., & Pillai, P. (2016) · European journal of plant pathology · doi:10.1007/s10658-016-0865-2 · Cited by 41
“Plant defense being a plastic trait, the differential allocation of defense- related metabolites plays a crucial role in affording resistance to the invading pathogen (Meldau et al. 2012; Moreira et al. 2012).”
Background
Hitting the Sweet Spot: Glycans as Targets of Fungal Defense Effector Proteins
Künzler, M. (2015) · Molecules · doi:10.3390/molecules20058144 · Cited by 43 · see citing works
Effects of insect attack to stems on plant survival, growth, reproduction and photosynthesis
Stephens, A., & Westoby, M. (2015) · doi:10.1111/oik.01809 · Cited by 40
Leaf metabolic signatures induced by real and simulated herbivory in black mustard (Brassica nigra)
Papazian, S., Girdwood, T., Wessels, B., Poelman, E., Dicke, M., Moritz, T., & Albrectsen, B. (2019) · Metabolomics · doi:10.1007/s11306-019-1592-4 · Cited by 39
Stabilization of yield in plant genotype mixtures through compensation rather than complementation
Creissen, H. E., Jorgensen, T. H., & Brown, J. K. M. (2013) · Annals of Botany · doi:10.1093/aob/mct209 · Cited by 43 · see citing works
Deciphering Herbivory-Induced Gene-to-Metabolite Dynamics in Nicotiana attenuata Tissues Using a Multifactorial Approach1[C][W][OA]
Gulati, J., Kim, S.-G., Baldwin, I., & Gaquerel, E. (2013) · Plant Physiology · doi:10.1104/pp.113.217588 · Cited by 36
“Plant tissue-specific responses to insect herbivory are thought to be controlled by tissue-specific activation and interaction between hormone gene networks (Meldau et al., 2012).”
BackgroundSelf-citation
Rice Planthoppers
Cheng, J.-A., & Escalada, M. (2015) · Springer Netherlands · doi:10.1007/978-94-017-9535-7 · Cited by 36
“Moreover, calcium flux, protein kinase (such as CDPK and MAPK) cascades, and JA-, SA-, ethylene-, and H2O2-mediated signaling pathways have been confirmed to play a central role in shaping the specificity of herbivore-induced plant defense responses (Wu et al. 2007; Howe and Jander 2008; Wu and Baldwin 2010; Heinrich…”
Background
Evolutionary changes in the glucosinolate biosynthetic capacity in species representing Capsella, Camelina and Neslia genera.
Czerniawski, P., Piasecka, A., & Bednarek, P. (2020) · Phytochemistry · doi:10.1016/j.phytochem.2020.112571 · Cited by 35
Two-way plant mediated interactions between root-associated microbes and insects: from ecology to mechanisms
Pangesti, N., Pineda, A., Pieterse, C. M. J., Dicke, M., & van Loon, J. J. A. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00414 · Cited by 142 · see citing works
“Other plant hormones such as ethylene (ET), abscisic acid (ABA), cytokinin (CK), gibberellin (GA), and auxin function as modulators of the hormone signaling backbone (Robert-Seilaniantz et al., 2011; Meldau et al., 2012; Pieterse et al., 2012; Giron et al., 2013).”
BackgroundInfluential
“Real time” genetic manipulation: a new tool for ecological field studies
Schäfer, M., Brütting, C., Gase, K., Reichelt, M., Baldwin, I., & Meldau, S. (2013) · The Plant Journal · doi:10.1111/tpj.12301 · Cited by 32
Self-citation
Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure
Papazian, S., Khaling, E., Bonnet, C. B., Lassueur, S., Reymond, P., Möritz, T., Blande, J. D., & Albrectsen, B. R. (2016) · PLANT PHYSIOLOGY · doi:10.1104/pp.16.01318 · Cited by 47 · see citing works
“…responses are not fully understood, but a tradeoff between growth and defense appears to determine how plants rearrange their metabolism and redirect primary resources to the production of specialized defensive compounds (Schwachtje and Baldwin, 2008; Tang et al., 2009; Meldau et al., 2012).”
Background
Cytokinin concentrations and CHASE-DOMAIN CONTAINING HIS KINASE 2 (NaCHK2)- and NaCHK3-mediated perception modulate herbivory-induced defense signaling and defenses in Nicotiana attenuata.
Schäfer, M., Meza-Canales, I. D., Brütting, C., Baldwin, I., & Meldau, S. (2015) · New Phytologist · doi:10.1111/nph.13404 · Cited by 31
“(3) Indirect interactions: CKs might influence herbivory-inducible defense responses indirectly, by up- or down-regulating other hormonal pathways, such as auxins and gibberellins, which subsequently leads to changes in JA sensitivity (Meldau et al., 2012).”
BackgroundSelf-citation
Cell cultures of Maytenus ilicifolia Mart. are richer sources of quinone-methide triterpenoids than plant roots in natura
Coppede, J. D. S., Pina, E. S., Paz, T. A., Fachin, A. L., Marins, M., Bertoni, B. W., França, S. D. C., & Pereira, A. M. S. (2014) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-014-0459-7 · Cited by 27 · see citing works
“It is generally accepted that young leaves and roots produce higher amounts of secondary metabolites in comparison with their older counterparts for the purpose of protection (Meldau et al. 2012).”
Changes in cytokinins are sufficient to alter developmental patterns of defense metabolites in Nicotiana attenuata
Brütting, C., Schäfer, M., Vaňková, R., Gase, K., Baldwin, I., & Meldau, S. (2017) · The Plant Journal · doi:10.1111/tpj.13316 · Cited by 28
Self-citation
Niches and routes of transmission of Xanthomonas citri pv. fuscans to bean seeds
Darrasse, A., Barret, M., Cesbron, S., Compant, S., & Jacques, M. (2017) · Plant and Soil · doi:10.1007/s11104-017-3329-3 · Cited by 28
Variation in production of cyanogenic glucosides during early plant development: A comparison of wild and domesticated sorghum
Cowan, M. F., Blomstedt, C. K., Møller, B. L., Henry, R. J., & Gleadow, R. M. (2021) · Phytochemistry · doi:10.1016/j.phytochem.2020.112645 · Cited by 30 · see citing works
Both Biosynthesis and Transport Are Involved in Glucosinolate Accumulation During Root-Herbivory in Brassica rapa
Touw, A., Mogena, A. V., Maedicke, A., Sontowski, R., van Dam, N., & Tsunoda, T. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2019.01653 · Cited by 27
Root Microbiome Assemblage is Modulated by Plant Host Factors
Lakshmanan, V. (2015) · doi:10.1016/bs.abr.2015.09.004 · Cited by 27
Differences in resource use lead to coexistence of seed-transmitted microbial populations
Torres-Cortés, G., Garcia, B. J., Compant, S., Rezki, S., Jones, P., Préveaux, A., Briand, M., Roulet, A., Bouchez, O., Jacobson, D. A., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-42865-9 · Cited by 26
Establishment and analysis of in vitro biomass from Salvia corrugata Vahl. and evaluation of antimicrobial activity.
Bisio, A., Fraternale, D., Schito, A., Parricchi, A., Piaz, F. D., Ricci, D., Giacomini, M., Ruffoni, B., & de Tommasi, N. (2016) · Phytochemistry · doi:10.1016/j.phytochem.2015.12.017 · Cited by 24
Direct and indirect resistance of sugarcane to Diatraea saccharalis induced by jasmonic acid
Sanches, P., Santos, F., Peñaflor, M. G. V., & Bento, J. (2017) · Bulletin of entomological research · doi:10.1017/s0007485317000372 · Cited by 23
“JA, the main phytohormone responsible for signal-transduction pathways in plants damaged by chewing insects (Wasternack & Hause, 2013), and its catabolites (methyl jasmonate [MeJA], cis-jasmone) have been widely studied as elicitors in plants, against not only insect pests but also pathogen infections (Antico et al.,…”
Background
Identification of a molecular dialogue between developing seeds of Medicago truncatula and seedborne xanthomonads.
Terrasson, E., Darrasse, A., Righetti, K., Buitink, J., Lalanne, D., Vu, B. L., Pelletier, S., Bolingue, W., Jacques, M., & Leprince, O. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv167 · Cited by 23
“Accordingly, young or reproductive organs are expected to exhibit higher basal levels or stronger induced defence responses than other plant structures (Meldau et al., 2012; Neilson et al., 2013).”
Background
Just in time
Baldwin, I., & Meldau, S. (2013) · Plant Signalling & Behavior · doi:10.4161/psb.24410 · Cited by 23 · see citing works
Self-citation
Locally and systemically induced glucosinolates follow optimal defence allocation theory upon root herbivory
Tsunoda, T., Großer, K., & Dam, N. M. (2018) · Functional Ecology · doi:10.1111/1365-2435.13147 · Cited by 22
“Despite the ecological relevance of root herbivory, research on optimal defence patterns in root systems is still in its infancy (Meldau et al., 2012; Robert et al., 2012; Tsunoda, Krosse, et al., 2017).”
Background
Spatiotemporal heterogeneity of tomato induced defense responses affects spider mite performance and behavior
Schimmel, B. C., Ataíde, L. M. S., & Kant, M. (2017) · Plant Signalling & Behavior · doi:10.1080/15592324.2017.1370526 · Cited by 20
“differ significantly in magnitude and/or in the timing of induction across plant age, developmental stage and tissue type, as well as across abiotic conditions.(1,2,5) Heterogeneity in defensive responses is an important aspect of plant-herbivore interac-”
Background
Specificity of extrafloral nectar induction by herbivores differs among native and invasive populations of tallow tree.
Wang, Y., Carrillo, J., Siemann, E., Wheeler, G., Zhu, L., Gu, X., & Ding, J.-Q. (2013) · Annals of Botany · doi:10.1093/aob/mct129 · Cited by 20
Evolutionary metabolomics of specialized metabolism diversification in the genus Nicotiana highlights N- acylnornicotine innovations
Elser, D., Pflieger, D., Villette, C., Moegle, B., Miesch, L., & Gaquerel, E. (2023) · Science Advances · doi:10.1126/sciadv.ade8984 · Cited by 24 · see citing works
“Analyzing tissue-specific metabolomes is also critical to test ecological theories of plant investments into metabolic defenses such as the optimal defense theory that predicts greater metabolic defense accumulation in developmental stages/tissues with higher organismic-level fitness contribution and/or greater predat…”
Background
Does the chemistry of fungal pigments demand the existence of photoactivated defense strategies in basidiomycetes?
Siewert, B. (2021) · Photochemical and Photobiological Sciences · doi:10.1007/s43630-021-00034-w · Cited by 19
Developmentally regulated activation of defense allows for rapid inhibition of infection in age-related resistance to Phytophthora capsici in cucumber fruit
Mansfeld, B. N., Colle, M., Zhang, C., Lin, Y., & Grumet, R. (2020) · BMC Genomics · doi:10.1186/s12864-020-07040-9 · Cited by 26 · see citing works
“While providing protection in agricultural systems 58 and potentially playing an important role in the evolution and optimization of host resistance [9], 59”
Background
Stunted Growth Caused by Blast Disease in Rice Seedlings Is Associated with Changes in Phytohormone Signaling Pathways
Jiang, C.-J., Liu, X.-L., Liu, X.-Q., Zhang, H., Yu, Y., & Liang, Z.-W. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01558 · Cited by 19
“…than deploying defense mechanisms uniformly across different tissues, plants prioritize protecting the tissues that contribute more to a plant’s future fitness, such as young sink tissues and reproductive structures (optimal defense hypothesis, ODH) (Meldau et al., 2012; Meldau and Baldwin, 2013).”
Background
Factors Influencing the Production and Chemical Composition of Essential Oils in Aromatic Plants from Brazil
Boaro, C. S. F., Vieira, M. A. R., Campos, F. G., Ferreira, G., De‐la‐Cruz‐Chacón, I., & Marques, M. O. M. (2019) · Springer eBooks · doi:10.1007/978-3-030-16546-8_2 · Cited by 18 · see citing works
Herbivore-Induced Defenses in Rice and Their Potential Application in Rice Planthopper Management
Lou, Y., Hu, L., & Li, J. (2014) · Springer eBooks · doi:10.1007/978-94-017-9535-7_5 · Cited by 11 · see citing works
“Moreover, calcium flux, protein kinase (such as CDPK and MAPK) cascades, and JA-, SA-, ethylene-, and H2O2-mediated signaling pathways have been confirmed to play a central role in shaping the specificity of herbivore-induced plant defense responses (Wu et al. 2007; Howe and Jander 2008; Wu and Baldwin 2010; Heinrich…”
Background
It’s a matter of time: the role of transcriptional regulation in the circadian clock-pathogen crosstalk in plants
de Leone, M. J., Hernando, C. E., Mora‐García, S., & Yanovsky, M. J. (2020) · Transcription · doi:10.1080/21541264.2020.1820300 · Cited by 20 · see citing works
“This hypothesis establishes that plants preferentially assign resources to the defense of tissues that are either more likely to be attacked or more valuable, resulting in tissue-specific “defense on demand” through the integration of developmental and defense signaling pathways [90,91].”
Background
FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes
Fernández‐Calvo, P., Iñigo, S., Glauser, G., Bossche, R. V., Tang, M., Li, B., Clercq, R. D., Durand, A. N., Eeckhout, D., Gevaert, K., et al. (2020) · New Phytologist · doi:10.1111/nph.16586 · Cited by 33 · see citing works
Bioactive farina of Notholaena sulphurea (Pteridaceae): Morphology and histochemistry of glandular trichomes
Rodriguez, A., Derita, M., Borkosky, S., Socolsky, C., Bardón, A., & Hernández, M. (2018) · doi:10.1016/j.flora.2018.01.008 · Cited by 18
Do phytoliths play an antiherbivory role in southwest Asian Asteraceae species and to what extent
Katz, O., Lev-Yadun, S., & Bar, P. (2014) · doi:10.1016/j.flora.2014.03.010 · Cited by 18
Plant biology: Electric defence
Christmann, A., & Grill, E. (2013) · Nature · doi:10.1038/500404a · Cited by 18
TOR coordinates Cytokinin and Gibberellin signals mediating development and defense
Marash, I., Gupta, R., Anand, G., Leibman-Markus, M., Lindner, N., Israeli, A., Nir, D., Avni, A., & Bar, M. (2023) · bioRxiv · doi:10.1101/2022.03.07.483332 · Cited by 17
“When pathogens attack, CK increases and GA decreases (Meldau et al., 2012; Gupta et al 2020), and TOR becomes less active (Margalha et al., 2019), promoting disease resistance.”
Background
Root-Lesion Nematodes Suppress Cabbage Aphid Population Development by Reducing Aphid Daily Reproduction
Hol, W., Raaijmakers, C., Mons, I., Meyer, K. M., & van Dam, N. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00111 · Cited by 17
Intraspecific variation in plant‐associated herbivore communities is phylogenetically structured in Brassicaceae
Mertens, D., Bouwmeester, K., & Poelman, E. (2021) · Ecology Letters · doi:10.1111/ele.13852 · Cited by 16
“Plants evolved inducible defences that are activated upon recognition of attack to save metabolic costs associated with production and maintenance of defence when herbivores are absent (Meldau et al., 2012).”
Background
Chemical profiling of camptothecin and methoxy camptothecin in Nothapodytes nimmoniana Grah. (Mabb.) during seed development, seed germination and their effects on seed-borne pathogens
Sarika, G., Amruta, N., Kandikattu, H. K., Basavaraju, G. V., Suma, H. K., Manjunath, B. L., & Sravani, C. (2019) · South African Journal of Botany · doi:10.1016/j.sajb.2019.02.003 · Cited by 17 · see citing works
Optimal chemical defence allocation in roots: where, why and how?
Touw, A., & Dam, N. M. (2023) · Phytochemistry Reviews · doi:10.1007/s11101-023-09872-1 · Cited by 15
“In Brassicaceae, induced responses in the root system are most robust in the most valuable root class (Tsunoda et al. 2018), similar to above-ground tissues (reviewed in Meldau et al. 2012).”
Influential
Comparative transcriptomic analyses of glucosinolate metabolic genes during the formation of Chinese kale seeds
Zhao, Y., Chen, Z.-Y., Chen, J.-X., Chen, B., Tang, W., Chen, X.-D., Lai, Z., & Guo, R.-F. (2021) · BMC Plant Biology · doi:10.1186/s12870-021-03168-2 · Cited by 15
“The distribution of GS over different parts follows optimal defense theory which allows plants to allocate defense compounds preferentially to the valuable plant parts which are also attractive to potential attackers [38].”
Background
Correlations among morphological and biochemical traits in high‐cannabidiol hemp ( Cannabis sativa L.)
Stack, G. M., Carlson, C. H., Toth, J. A., Philippe, G., Crawford, J. L., Hansen, J. L., Viands, D. R., Rose, J. K. C., & Smart, L. B. (2023) · Plant Direct · doi:10.1002/pld3.503 · Cited by 17 · see citing works
“Ecological theory predicts ontogenetic and tissue-specific variation in the concentration of plant secondary metabolites, primarily in the context of herbivore resistance (Barton & Boege, 2017; McKey, 1974; Meldau et al., 2012; Pavia et al., 2002; Schuman & Baldwin, 2016; van Dam, 2009).”
Background
Divergent host plant utilization by adults and offspring is related to intra-plant variation in chemical defenses.
Mason, C., Long, D., Lindroth, R., & Hoover, K. (2019) · Journal of Animal Ecology · doi:10.1111/1365-2656.13063 · Cited by 14
Beyond the Canon: Within-Plant and Population-Level Heterogeneity in Jasmonate Signaling Engaged by Plant-Insect Interactions
Li, D., Baldwin, I., & Gaquerel, E. (2016) · Plants · doi:10.3390/plants5010014 · Cited by 14
“Tissue specificity in metabolism in response to herbivory is thought to be mediated, in part, by tissue-specific deviations in jasmonate signaling [42].”
BackgroundSelf-citation
Jasmonates in Plant Growth and Stress Responses
Wasternack, C. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0491-4_8 · Cited by 16 · see citing works
Accumulation of Secondary Metabolites of Rhodiola semenovii Boriss. In Situ in the Dynamics of Growth and Development
Terletskaya, N. V., Korbozova, N. K., Grazhdannikov, A. E., Seitimova, G. A., Meduntseva, N. D., & Kudrina, N. O. (2022) · Metabolites · doi:10.3390/metabo12070622 · Cited by 15 · see citing works
“Therefore, the comparatively low amount of beneficial secondary metabolites, particularly in the shoots of immature plants, was clearly reflected in our experiment on the detection of SM, indicating that young plants have an increased requirement for primary metabolites and nutrients [33,34].”
Background
Optimal Defense Theory 2.0: tissue-specific stress defense prioritization as an extra layer of complexity
Wolinska, K., & Berens, M. L. (2019) · Communicative & Integrative Biology · doi:10.1080/19420889.2019.1625661 · Cited by 13
“that organisms put more resources into protecting their most valuable tissues to increase fitness [26].”
Background
Virus-Induced Gene Silencing Using Tobacco Rattle Virus as a Tool to Study the Interaction between Nicotiana attenuata and Rhizophagus irregularis
Groten, K., Pahari, N., Xu, S.-Q., van Doorn, M. M., & Baldwin, I. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136234 · Cited by 13
Self-citation
‘Click’ chemistry synthesis and capillary electrophoresis study of 1,4‐linked 1,2,3‐triazole AZT‐systemin conjugate
Dobkowski, M. N., Szychowska, A., Pieszko, M., Miszka, A., Wojciechowska, M., Alenowicz, M., Ruczyński, J., Rekowski, P., Celewicz, L., Barciszewski, J., et al. (2014) · Journal of Peptide Science · doi:10.1002/psc.2653 · Cited by 13

Authors: Meldau, S., Erb, M., & Baldwin, I. T.
Affiliations: Max Planck Society (DE)
Corresponding author: Meldau, Stefan
ORCID: Erb, Matthias
Baldwin, Ian T.
Venue: Annals of Botany
Publisher: Oxford University Press (OUP)
Published: 2012-09-28
Volume: 110
Issue: 8
Pages: 1503-1514
ISSN: 0305-7364 (ISSN-L)
1095-8290
DOI: 10.1093/aob/mcs212
PMC: PMC3503495
OpenAlex: W2072280600
Cited by: 197
References: 0
Citations by year: 2026: 11 · 2025: 5 · 2024: 18 · 2023: 17 · 2022: 12 · 2021: 18 · 2020: 16 · 2019: 10 · 2018: 10 · 2017: 12 · 2016: 15 · 2015: 17 · 2014: 18 · 2013: 17
FWCI: 1.68
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Annals of Botany (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
BORIS (University Library Bern) (submittedVersion, other-oa)
MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
Open Access CRIS of the University of Bern
Topics: Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
Keywords: induced defense, jasmonic acid, plant hormones, auxin, cytokinins, gibberellin, brassinosteroids, sink tissues, herbivory, plant development, plant-pathogen interaction, plant-herbivore interactions
MeSH terms: Plant Diseases, Plant Growth Regulators, Plants, Signal Transduction, Plant Components, Aerial, Plant Immunity, Herbivory, Plant Development

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Defence on demand: mechanisms behind optimal defence patterns

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Record

About these checks