The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Specification of the anteroposterior axis in Caenorhabditis elegans
Abstract
Anteroposterior asymmetries are apparent in C. elegans development before the first cell division. Here we identify the cue that specifies the anteroposterior axis, and investigate how this cue is interpreted to generate initial asymmetry. In C. elegans, the sperm normally enters the egg in an invariant position. We have found that causing fertilisation to occur in the abnormal end of the egg completely reverses the orientation of the anteroposterior axis, but gives otherwise normal development. This result suggests that a component of the sperm normally specifies the anteroposterior axis. We have found that a cytoplasmic rearrangement in the uncleaved zygote is directed by the sperm, suggesting a mechanism by which the sperm may specify the axis. The results additionally reveal that the C. elegans oocyte is constructed with no axis prespecified in the form of asymmetrically localised cytoplasmic determinants.
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Cites
The Nematode Caenorhabditis elegans
Wood, W. B. (1988) · Cold Spring Harbor Laboratory eBooks · Cited by 2,820
Guo, S., & Kemphues, K. J. (1995) · Cell · doi:10.1016/0092-8674(95)90082-9 · Cited by 1,122
Identification of genes required for cytoplasmic localization in early C. elegans embryos
Kemphues, K. J., Priess, J. R., Morton, D. G., & Cheng, N. (1988) · Cell · doi:10.1016/s0092-8674(88)80024-2 · Cited by 859
Bray, D., & White, J. G. (1988) · Science · doi:10.1126/science.3277283 · Cited by 574
Development of the reproductive system of Caenorhabditis elegans
Hirsh, D., Oppenheim, D., & Klass, M. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90267-0 · Cited by 555
Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos
Strome, S., & Wood, W. B. (1983) · Cell · doi:10.1016/0092-8674(83)90203-9 · Cited by 534
Identification and cloning of localized maternal RNAs from xenopus eggs
Rebagliati, M. R., Weeks, D. L., Harvey, R. P., & Melton, D. A. (1985) · Cell · doi:10.1016/0092-8674(85)90273-9 · Cited by 456
Fertilization and sperm competition in the nematodeCaenorhabditis elegans
Ward, S., & Carrel, J. S. (1979) · Developmental Biology · doi:10.1016/0012-1606(79)90069-1 · Cited by 452
Etemad-Moghadam, B., Guo, S., & Kemphues, K. J. (1995) · Cell · doi:10.1016/0092-8674(95)90187-6 · Cited by 414
Processed Vg1 protein is an axial mesoderm inducer in xenopus
Thomsen, G. H., & Melton, D. A. (1993) · Cell · doi:10.1016/0092-8674(93)80045-g · Cited by 413
Cited by
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
Rocheleau, C. E., Downs, W. D., Lin, R., Wittmann, C., Bei, Y., Cha, Y.-H., Ali, M., Priess, J. R., & Mello, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80531-0 · Cited by 660
Mechanisms of asymmetric cell division: flies and worms pave the way
Gönczy, P. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2388 · Cited by 489
Benton, R., & Johnston, D. S. (2003) · Cell · doi:10.1016/s0092-8674(03)00938-3 · Cited by 410
Harris, T. J. C., & Peifer, M. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200505127 · Cited by 295
Hamill, D. R., Severson, A. F., Carter, J. C., & Bowerman, B. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00327-1 · Cited by 278
Holland, L. Z. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00109-x · Cited by 59
(2022) · doi:10.7554/elife.83992 · Cited by 14
Metadata
- Authors
- Goldstein, B., & Hird, S. N.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1996-05-01
- Volume
- 122
- Issue
- 5
- Pages
- 1467-1474
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2114056852
- Cited by
- 320
- References
- 40
- FWCI
- 4.70
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
