Development of the thyroid gland

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

Agrawal, N., Akbani, R., Aksoy, B. A., Ally, A., Arachchi, H., Asa, S. L., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., et al. (2014) · Cell · doi:10.1016/j.cell.2014.09.050 · Cited by 3,062

Isl1 Identifies a Cardiac Progenitor Population that Proliferates Prior to Differentiation and Contributes a Majority of Cells to the Heart

Cai, C.-L., Liang, X., Shi, Y., Chu, P.-H., Pfaff, S. L., Chen, J., & Evans, S. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00363-0 · Cited by 1,610

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

Kimura, S., Hara, Y., Pineau, T., Fernandez-Salguero, P., Fox, C. H., Ward, J. M., & Gonzalez, F. J. (1996) · Genes & Development · doi:10.1101/gad.10.1.60 · Cited by 1,222

FGF10 Acts as a Major Ligand for FGF Receptor 2 IIIb in Mouse Multi-Organ Development

Ohuchi, H., Hori, Y., Yamasaki, M., Harada, H., Sekine, K., Kato, S., & Itoh, N. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3721 · Cited by 636

Follicular cells of the thyroid gland require Pax8 gene function

Mansouri, A., Chowdhury, K., & Gruss, P. (1998) · Nature Genetics · doi:10.1038/ng0598-87 · Cited by 622

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

Ang, S.-L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S., Rossant, J., & Zaret, K. S. (1993) · Development · doi:10.1242/dev.119.4.1301 · Cited by 618 · cited 2×

Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm

Monaghan, A. P., Kaestner, K. H., Grau, E., & Schütz, G. (1993) · Development · doi:10.1242/dev.119.3.567 · Cited by 497

The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation

Barbera, J. P. M., Clements, M., Thomas, P., Rodriguez, T., Meloy, D., Kioussis, D., & Beddington, R. S. P. (2000) · Development · doi:10.1242/dev.127.11.2433 · Cited by 474

Dependence of Thymus Development on Derivatives of the Neural Crest

Bockman, D. E., & Kirby, M. L. (1984) · Science · doi:10.1126/science.6606851 · Cited by 472

Defects in Tracheoesophageal and Lung Morphogenesis inNkx2.1(−/−) Mouse Embryos

Minoo, P., Su, G., Drum, H., Bringas, P., & Kimura, S. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9234 · Cited by 460

Netrins: versatile extracellular cues with diverse functions

Sun, K. L. W., Correia, J. P., & Kennedy, T. E. (2011) · Development · doi:10.1242/dev.044529 · Cited by 427

Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia

Clifton-Bligh, R. J., Wentworth, J. M., Heinz, P., Crisp, M. S., John, R., Lazarus, J. H., Ludgate, M., & Chatterjee, V. K. (1998) · Nature Genetics · doi:10.1038/1294 · Cited by 423

Regulation of pancreas development by hedgehog signaling

Hebrok, M., Kim, S. K., St-Jacques, B., McMahon, A. P., & Melton, D. A. (2000) · Development · doi:10.1242/dev.127.22.4905 · Cited by 412

Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells

Longmire, T. A., Ikonomou, L., Hawkins, F., Christodoulou, C., Cao, Y., Jean, J. C., Kwok, L. W., Mou, H., Rajagopal, J., Shen, S. S., et al. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.01.019 · Cited by 384

Generation of functional thyroid from embryonic stem cells

Antonica, F., Kasprzyk, D. F., Opitz, R., Iacovino, M., Liao, X.-H., Dumitrescu, A. M., Refetoff, S., Peremans, K., Manto, M., Kyba, M., et al. (2012) · Nature · doi:10.1038/nature11525 · Cited by 359

Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas

Pearse, A. G. E., & Polak, J. M. (1971) · Gut · doi:10.1136/gut.12.10.783 · Cited by 358

A mouse model for hereditary thyroid dysgenesis and cleft palate

De Felice, M., Ovitt, C., Biffali, E., Rodriguez-Mallon, A., Arra, C., Anastassiadis, K., Macchia, P. E., Mattei, M.-G., Mariano, A., Schöler, H., et al. (1998) · Nature Genetics · doi:10.1038/1289 · Cited by 337

Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung

Serls, A. E., Doherty, S., Parvatiyar, P., Wells, J. M., & Deutsch, G. H. (2005) · Development · doi:10.1242/dev.01570 · Cited by 316

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency

Krude, H., Schütz, B., Biebermann, H., von Moers, A., Schnabel, D., Neitzel, H., Tönnies, H., Weise, D., Lafferty, A. R. A., Schwarz, S., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci14341 · Cited by 312

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3

Tourtellotte, W. G., & Milbrandt, J. (1998) · Nature Genetics · doi:10.1038/1757 · Cited by 306

Cell fate control by pioneer transcription factors

Iwafuchi-Doi, M., & Zaret, K. S. (2016) · Development · doi:10.1242/dev.133900 · Cited by 304

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development

Bort, R., Signore, M., Tremblay, K., Barbera, J. P. M., & Zaret, K. S. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2005.11.006 · Cited by 285

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency

Krude, H., Schütz, B., Biebermann, H., von Moers, A., Schnabel, D., Neitzel, H., Tönnies, H., Weise, D., Lafferty, A., Schwarz, S., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214341 · Cited by 268

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

Bort, R., Martinez-Barbera, J. P., Beddington, R. S. P., & Zaret, K. S. (2004) · Development · doi:10.1242/dev.00965 · Cited by 267 · cited 2×

Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor

Kim, S. K., & Melton, D. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13036 · Cited by 265

Fibroblast Growth Factor Receptor 2-IIIb Acts Upstream of Shh and Fgf4 and Is Required for Limb Bud Maintenance but Not for the Induction of Fgf8, Fgf10, Msx1, or Bmp4

Revest, J.-M., Spencer-Dene, B., Kerr, K., De Moerlooze, L., Rosewell, I., & Dickson, C. (2001) · Developmental Biology · doi:10.1006/dbio.2000.0144 · Cited by 262

Thyroid transcription factors in development, differentiation and disease

Fernández, L. P., López-Márquez, A., & Santisteban, P. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.186 · Cited by 258

Hemichordate genomes and deuterostome origins

Simakov, O., Kawashima, T., Marlétaz, F., Jenkins, J., Koyanagi, R., Mitros, T., Hisata, K., Bredeson, J., Shoguchi, E., Gyoja, F., et al. (2015) · Nature · doi:10.1038/nature16150 · Cited by 255

Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland

Postiglione, M. P., Parlato, R., Rodriguez-Mallon, A., Rosica, A., Mithbaokar, P., Maresca, M., Marians, R. C., Davies, T. F., Zannini, M. S., De Felice, M., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242328999 · Cited by 251

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

Liao, J. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh176 · Cited by 248

Multiple endocrine neoplasia type 2: An overview

Moline, J., & Eng, C. (2011) · Genetics in Medicine · doi:10.1097/gim.0b013e318216cc6d · Cited by 228

Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development

Zhang, Z., Huynh, T., & Baldini, A. (2006) · Development · doi:10.1242/dev.02539 · Cited by 210

A Search for the Possible Molecular Mechanisms of Thyroid Dysgenesis: Sex Ratios and Associated Malformations

Devos, H., Rodd, C., Gagné, N., Laframboise, R., & Van Vliet, G. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.7.5831 · Cited by 204

Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells

Kurmann, A. A., Serra, M., Hawkins, F., Rankin, S. A., Mori, M., Astapova, I., Ullas, S., Lin, S., Bilodeau, M., Rossant, J., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.09.004 · Cited by 204

The FoxA factors in organogenesis and differentiation

Kaestner, K. H. (2010) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2010.06.005 · Cited by 197

An integrated regulatory network controlling survival and migration in thyroid organogenesis

Parlato, R., Rosica, A., Rodriguez-Mallon, A., Affuso, A., Postiglione, M. P., Arra, C., Mansouri, A., Kimura, S., Di Lauro, R., & De Felice, M. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.08.048 · Cited by 179

Missense Mutation in the Transcription Factor NKX2–5: A Novel Molecular Event in the Pathogenesis of Thyroid Dysgenesis

Dentice, M., Cordeddu, V., Rosica, A., Ferrara, A. M., Santarpia, L., Salvatore, D., Chiovato, L., Perri, A., Moschini, L., Fazzini, C., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1350 · Cited by 178

pax2.1 is required for the development of thyroid follicles in zebrafish

Wendl, T., Lun, K., Mione, M., Favor, J., Brand, M., Wilson, S. W., & Rohr, K. B. (2002) · Development · doi:10.1242/dev.129.15.3751 · Cited by 177

A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice

Searcy, R. D., Vincent, E. B., Liberatore, C. M., & Yutzey, K. E. (1998) · Development · doi:10.1242/dev.125.22.4461 · Cited by 171

Discordance of Monozygotic Twins for Thyroid Dysgenesis: Implications for Screening and for Molecular Pathophysiology

Perry, R., Heinrichs, C., Bourdoux, P., Khoury, K., Szöts, F., Dussault, J. H., Vassart, G., & Van Vliet, G. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2001-011995 · Cited by 167

Analysis of origin and growth of the thyroid gland in zebrafish

Alt, B., Reibe, S., Feitosa, N. M., Elsalini, O. A., Wendl, T., & Rohr, K. B. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20831 · Cited by 164

Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations

Arnold, J. S., Werling, U., Braunstein, E. M., Liao, J., Nowotschin, S., Edelmann, W., Hebert, J. M., & Morrow, B. E. (2006) · Development · doi:10.1242/dev.02264 · Cited by 164

TTF-1 Phosphorylation Is Required for Peripheral Lung Morphogenesis, Perinatal Survival, and Tissue-specific Gene Expression

deFelice, M., Silberschmidt, D., DiLauro, R., Xu, Y., Wert, S. E., Weaver, T. E., Bachurski, C. J., Clark, J. C., & Whitsett, J. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304885200 · Cited by 163

Iodine Metabolism and Thyroid-Related Functions in Organisms Lacking Thyroid Follicles: Are Thyroid Hormones also Vitamins?

Eales, J. G. (1997) · Experimental Biology and Medicine · doi:10.3181/00379727-214-44098 · Cited by 157

A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis

Guo, C., Sun, Y., Zhou, B., Adam, R. M., Li, X., Pu, W. T., Morrow, B. E., Moon, A., & Li, X. (2011) · Journal of Clinical Investigation · doi:10.1172/jci44630 · Cited by 148

Morphogenesis of the thyroid gland

Fagman, H., & Nilsson, M. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.12.008 · Cited by 145

Pax-8–PPAR-γ fusion protein in thyroid carcinoma

Raman, P., & Koenig, R. J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.115 · Cited by 144

A Novel Mutation (Q40P) in PAX8 Associated with Congenital Hypothyroidism and Thyroid Hypoplasia: Evidence for Phenotypic Variability in Mother and Child

Congdon, T., Nguyen, L. Q., Nogueira, C. R., Habiby, R. L., Medeiros-Neto, G. A., & Kopp, P. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.8.7765 · Cited by 142

Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development

Zhang, Z., Cerrato, F., Xu, H., Vitelli, F., Morishima, M., Vincentz, J. W., Furuta, Y., Ma, L., Martin, J. F., Baldini, A., et al. (2005) · Development · doi:10.1242/dev.02086 · Cited by 132

Gut endocrine cell development

May, C. L., & Kaestner, K. H. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.12.009 · Cited by 127

The developing mouse thyroid: Embryonic vessel contacts and parenchymal growth pattern during specification, budding, migration, and lobulation

Fagman, H., Andersson, L., & Nilsson, M. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20653 · Cited by 126

A Mouse Model Demonstrates a Multigenic Origin of Congenital Hypothyroidism

Amendola, E., Luca, P. D., Macchia, P. E., Terracciano, D., Rosica, A., Chiappetta, G., Kimura, S., Mansouri, A., Affuso, A., Arra, C., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0882 · Cited by 125

CELL POPULATION KINETICS IN DOG AND HUMAN ADULT THYROID

COCLET, J., Foureau, F., Ketelbant, P., et al. (1989) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1989.tb01290.x · Cited by 124

Congenital hypothyroidism: recent advances

Wassner, A. J., & Brown, R. S. (2015) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000181 · Cited by 123

DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis

Fernández, P., Zahonero, C., & Sánchez‐Gómez, P. (2015) · Molecular & Cellular Oncology · doi:10.4161/23723548.2014.970048 · Cited by 121

Retinoic Acid Signaling Organizes Endodermal Organ Specification along the Entire Antero-Posterior Axis

Bayha, E., Jørgensen, M. C., Serup, P., & Grapin‐Botton, A. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005845 · Cited by 121

Characterization of a Novel Loss of Function Mutation of PAX8 in a Familial Case of Congenital Hypothyroidism with In-Place, Normal-Sized Thyroid

Meeus, L., Gilbert, B., Rydlewski, C., Parma, J., Lienhardt-Roussie, A., Abramowicz, M., Vilain, C. N., Christophe, D., Costagliola, S., & Vassart, G. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0166 · Cited by 118

Zebrafish hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors

Elsalini, O. A., von Gartzen, J., Cramer, M., & Rohr, K. B. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00436-6 · Cited by 117

Genetic Deletion of Sonic Hedgehog Causes Hemiagenesis and Ectopic Development of the Thyroid in Mouse

Fagman, H., Grände, M., Gritli-Linde, A., & Nilsson, M. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63745-5 · Cited by 116

Revising the embryonic origin of thyroid C cells

Johansson, E., Andersson, L., Örnros, J., Carlsson, T., Ingeson-Carlsson, C., Liang, S., Dahlberg, J., Jansson, S. K. G., Parrillo, L., Zoppoli, P., et al. (2015) · Development · doi:10.1242/dev.126581 · Cited by 114

Arteries define the position of the thyroid gland during its developmental relocalisation

Alt, B., Elsalini, O. A., Schrumpf, P., Haufs, N., Lawson, N. D., Schwabe, G. C., Mundlos, S., Grüters, A., Krude, H., & Rohr, K. B. (2006) · Development · doi:10.1242/dev.02550 · Cited by 110

Thyroid-Specific Enhancer-Binding Protein/NKX2.1 Is Required for the Maintenance of Ordered Architecture and Function of the Differentiated Thyroid

Kusakabe, T., Kawaguchi, A., Hoshi, N., Kawaguchi, R., Hoshi, S., & Kimura, S. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0327 · Cited by 110

Familial Forms of Thyroid Dysgenesis among Infants with Congenital Hypothyroidism

Castanet, M., Lyonnet, S., Bonaïti‐Pellié, C., Polak, M., Czernichow, P., & Léger, J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008103430614 · Cited by 99

Sodium/Iodide Symporter (NIS) Gene Expression Is the Limiting Step for the Onset of Thyroid Function in the Human Fetus

Szinnai, G., Lacroix, L., Carré, A., Guimiot, F., Talbot, M., Martinovic, J., Delezoide, A., Vekemans, M. J. J., Michiels, S., Caillou, B., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1450 · Cited by 98

Side Population Cells in the Mouse Thyroid Exhibit Stem/Progenitor Cell-Like Characteristics

Hoshi, N., Kusakabe, T., Taylor, B. J., & Kimura, S. (2007) · Endocrinology · doi:10.1210/en.2006-0490 · Cited by 96

Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development

Opitz, R., Maquet, E., Huisken, J., Antonica, F., Trubiroha, A., Pottier, G., Janssens, V., & Costagliola, S. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.09.011 · Cited by 91

The Forkhead Factor FoxE1 Binds to the Thyroperoxidase Promoter during Thyroid Cell Differentiation and Modifies Compacted Chromatin Structure

Cuesta, I., Zaret, K. S., & Santisteban, P. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00758-07 · Cited by 80

Committing Embryonic Stem Cells to Differentiate into Thyrocyte-Like Cells in Vitro

Lin, R.-Y., Kubo, A., Keller, G. M., & Davies, T. F. (2003) · Endocrinology · doi:10.1210/en.2002-0122 · Cited by 76

New Insights into FoxE1 Functions: Identification of Direct FoxE1 Targets in Thyroid Cells

Fernández, L. P., López‐Márquez, A., Martínez‐Montes, Á. M., Goméz-López, G., & Santisteban, P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062849 · Cited by 74

The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning

Fagman, H., Liao, J., Westerlund, J., Andersson, L., Morrow, B. E., & Nilsson, M. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl455 · Cited by 73

Transcriptional Repressor DREAM Interacts with Thyroid Transcription Factor-1 and Regulates Thyroglobulin Gene Expression

Rivas, M., Mellström, B., Naranjo, J. R., & Santisteban, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403526200 · Cited by 72

The amphioxus genome enlightens the evolution of the thyroid hormone signaling pathway

Paris, M., Brunet, F., Markov, G. V., Schubert, M., & Laudet, V. (2008) · Development Genes and Evolution · doi:10.1007/s00427-008-0255-7 · Cited by 71

Tumor-Associated Mast Cells in Thyroid Cancer

Visciano, C., Prevete, N., Liotti, F., & Marone, G. (2015) · International Journal of Endocrinology · doi:10.1155/2015/705169 · Cited by 68

Early developmental specification of the thyroid gland depends onhan-expressing surrounding tissue and on FGF signals

Wendl, T., Adzic, D., Schoenebeck, J. J., Scholpp, S., Brand, M., Yelon, D. L., & Rohr, K. B. (2007) · Development · doi:10.1242/dev.02872 · Cited by 68

On the Origin of Cells and Derivation of Thyroid Cancer: C Cell Story Revisited

Nilsson, M., & Williams, D. (2016) · European Thyroid Journal · doi:10.1159/000447333 · Cited by 68

Possible Non-Mendelian Mechanisms of Thyroid Dysgenesis

Deladoëy, J., Vassart, G., & Vliet, G. V. (2007) · Endocrine development · doi:10.1159/000106818 · Cited by 67

Directed Differentiation of Mouse Embryonic Stem Cells into Thyroid Follicular Cells

Arufe, M. C., Lü, M., Kubo, A., Keller, G. M., Davies, T. F., & Lin, R.-Y. (2006) · Endocrinology · doi:10.1210/en.2005-1239 · Cited by 67

Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning

Fagman, H., Amendola, E., Parrillo, L., Zoppoli, P., Marotta, P., Scarfò, M., De Luca, P., de Carvalho, D. P., Ceccarelli, M., De Felice, M., et al. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.08.015 · Cited by 67

Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons

Sloan, T. F. W., Qasaimeh, M. A., Juncker, D., Yam, P. T., & Charron, F. (2015) · PLoS Biology · doi:10.1371/journal.pbio.1002119 · Cited by 65

Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid

Kusakabe, T., Hoshi, N., & Kimura, S. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20655 · Cited by 63

Thyroid Growth and Cancer

Williams, D. (2015) · European Thyroid Journal · doi:10.1159/000437263 · Cited by 63

Testing putative hemichordate homologues of the chordate dorsal nervous system and endostyle: expression of NK2.1 (TTF‐1) in the acorn worm Ptychodera flava (Hemichordata, Ptychoderidae)

Takacs, C. M., Moy, V. N., & Peterson, K. J. (2002) · Evolution & Development · doi:10.1046/j.1525-142x.2002.02029.x · Cited by 63

Some Aspects of the Comparative Biochemistry of Iodine Utilization and the Evolution of Thyroidal Function

Gorbman, A. (1955) · Physiological Reviews · doi:10.1152/physrev.1955.35.2.336 · Cited by 63

Expression of Classical Cadherins in Thyroid Development: Maintenance of an Epithelial Phenotype throughout Organogenesis

Fagman, H., Grände, M., Edsbagge, J., Semb, H., & Nilsson, M. (2003) · Endocrinology · doi:10.1210/en.2003-0393 · Cited by 62

Comparative expression analysis of transcription factor genes in the endostyle of invertebrate chordates

Hiruta, J., Mazet, F., Yasui, K., Zhang, P., & Ogasawara, M. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20401 · Cited by 62

Cancer stem-like cells and thyroid cancer

Guo, Z., Hardin, H., & Lloyd, R. V. (2014) · Endocrine Related Cancer · doi:10.1530/erc-14-0002 · Cited by 61

Human Embryonic Stem Cells Form Functional Thyroid Follicles

Ma, R., Latif, R., & Davies, T. F. (2015) · Thyroid · doi:10.1089/thy.2014.0537 · Cited by 59

Anatomical and molecular reinvestigation of lamprey endostyle development provides new insight into thyroid gland evolution

Kluge, B., Renault, N., & Rohr, K. B. (2004) · Development Genes and Evolution · doi:10.1007/s00427-004-0450-0 · Cited by 59

Thyroglobulin Represents a Novel Molecular Architecture of Vertebrates

Holzer, G., Morishita, Y., Fini, J., Lorin, T., Gillet, B., Hughes, S., Tohmé, M., Deléage, G., DEMENEIX, B. A., Arvan, P. R., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.719047 · Cited by 57

Functional Zebrafish Studies Based on Human Genotyping Point to Netrin-1 as a Link Between Aberrant Cardiovascular Development and Thyroid Dysgenesis

Opitz, R., Hitz, M., Vandernoot, I., Trubiroha, A., Abu‐Khudir, R., Samuels, M. E., Désilets, V. A., Costagliola, S., Andelfinger, G., & Deladoëy, J. (2014) · Endocrinology · doi:10.1210/en.2014-1628 · Cited by 56

MSX1 and TGF- 3 are novel target genes functionally regulated by FOXE1

Venza, I., Visalli, M., Parrillo, L., Felice, M. D., Teti, D. V., & Venza, M. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq547 · Cited by 56

Theory on the evolutionary history of lamprey metamorphosis: role of reproductive and thyroid axes

Youson, J. H., & Sower, S. A. (2001) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(01)00341-4 · Cited by 54

Review: The Role of Neural Crest Cells in the Endocrine System

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Mechanisms of Thyroid Development and Dysgenesis

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