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Fibroblast growth factors: key players in regeneration and tissue repair.

Maddaluno, Luigi, Urwyler, Corinne, Werner, Sabine·2017·Development
DOI 10.1242/dev.152587
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Abstract

Tissue injury initiates a complex repair process, which in some organisms can lead to the complete regeneration of a tissue. In mammals, however, the repair of most organs is imperfect and results in scar formation. Both regeneration and repair are orchestrated by a highly coordinated interplay of different growth factors and cytokines. Among the key players are the fibroblast growth factors (FGFs), which control the migration, proliferation, differentiation and survival of different cell types. In addition, FGFs influence the expression of other factors involved in the regenerative response. Here, we summarize current knowledge on the roles of endogenous FGFs in regeneration and repair in different organisms and in different tissues and organs. Gaining a better understanding of these FGF activities is important for appropriate modulation of FGF signaling after injury to prevent impaired healing and to promote organ regeneration in humans.

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  • Modulation of multiple key cell-fate regulatory pathways, including attenuation of pSmad2,3 signaling by follistatin, is important for productive cell proliferation and regeneration in skeletal muscle, heart, and generally throughout the body.

    “Modulation of multiple key cell-fate regulatory pathways, including attenuation of pSmad2,3 signaling by follistatin, is important for productive cell proliferation and regeneration in skeletal muscle, heart and generally, throughout the body [77–79].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [79]

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Research works printed but not linked: 122

  1. Alzheimer, 2002, Fibroblast growth factors and neuroprotection, Adv. Exp. Med. Biol., 513, 335, 10.1007/978-1-4615-0123-7_12 · DOI
  2. Antoine, 2007, Expression and function of fibroblast growth factor (FGF) 9 in hepatic stellate cells and its role in toxic liver injury, Biochem. Biophys. Res. Commun., 361, 335, 10.1016/j.bbrc.2007.06.189 · DOI
  3. Armand, 2005, FGF6 regulates muscle differentiation through a calcineurin-dependent pathway in regenerating soleus of adult mice, J. Cell. Physiol., 204, 297, 10.1002/jcp.20302 · DOI
  4. Behr, 2010, Different endogenous threshold levels of Fibroblast Growth Factor-ligands determine the healing potential of frontal and parietal bones, Bone, 47, 281, 10.1016/j.bone.2010.05.008 · DOI
  5. Behr, 2010, Fgf-9 is required for angiogenesis and osteogenesis in long bone repair, Proc. Natl. Acad. Sci. USA, 107, 11853, 10.1073/pnas.1003317107 · DOI
  6. Behr, 2011, Fgf-18 is required for osteogenesis but not angiogenesis during long bone repair, Tissue Eng. Part A, 17, 2061, 10.1089/ten.tea.2010.0719 · DOI
  7. Bertrand, 2014, FGF signaling emerged concomitantly with the origin of Eumetazoans, Mol. Biol. Evol., 31, 310, 10.1093/molbev/mst222 · DOI
  8. Böhm, 2010, Regulation of liver regeneration by growth factors and cytokines, EMBO Mol. Med., 2, 294, 10.1002/emmm.201000085 · DOI
  9. Böhm, 2010, FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice, Gastroenterology, 139, 1385, 10.1053/j.gastro.2010.06.069 · DOI
  10. Bouzaffour, 2009, Fgf and Sdf-1 pathways interact during zebrafish fin regeneration, PLoS ONE, 4, e5824, 10.1371/journal.pone.0005824 · DOI
  11. Broadley, 1989, Monospecific antibodies implicate basic fibroblast growth factor in normal wound repair, Lab. Invest., 61, 571
  12. Brockes, 2008, Comparative aspects of animal regeneration, Annu. Rev. Cell Dev. Biol., 24, 525, 10.1146/annurev.cellbio.24.110707.175336 · DOI
  13. Cebrià, 2002, FGFR-related gene nou-darake restricts brain tissues to the head region of planarians, Nature, 419, 620, 10.1038/nature01042 · DOI
  14. Chen, 2002, Protection of the intestinal mucosa by intraepithelial gamma delta T cells, Proc. Natl. Acad. Sci. USA, 99, 14338, 10.1073/pnas.212290499 · DOI
  15. Chen, 2015, Transient laminin beta 1a induction defines the wound epidermis during zebrafish fin regeneration, PLoS Genet., 11, e1005437, 10.1371/journal.pgen.1005437 · DOI
  16. Danopoulos, 2017, Fibroblast growth factors in the gastrointestinal tract: twists and turns, Dev. Dyn., 246, 344, 10.1002/dvdy.24491 · DOI
  17. Del Rio-Tsonis, 1998, Regulation of lens regeneration by fibroblast growth factor receptor 1, Dev. Dyn., 213, 140, 10.1002/(SICI)1097-0177(199809)213:1<140::AID-AJA14>3.0.CO;2-6 · DOI
  18. D'Jamoos, 1998, Fibroblast growth factor receptors regulate the ability for hindlimb regeneration in Xenopus laevis, Wound Repair. Regen., 6, S-388, 10.1046/j.1460-9568.1998.60415.x · DOI
  19. Eming, 2014, Wound repair and regeneration: mechanisms, signaling, and translation, Sci. Transl. Med., 6, 265sr266, 10.1126/scitranslmed.3009337 · DOI · Paper page
  20. Finch, 2013, Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models, J. Cell. Mol. Med., 17, 1065, 10.1111/jcmm.12091 · DOI
  21. Fiore, 2000, Skeletal muscle regeneration is not impaired in Fgf6 -/- mutant mice, Biochem. Biophys. Res. Commun., 272, 138, 10.1006/bbrc.2000.2703 · DOI
  22. Fischer, 2005, Neural regeneration in the chick retina, Prog. Retin. Eye Res., 24, 161, 10.1016/j.preteyeres.2004.07.003 · DOI
  23. Floss, 1997, A role for FGF-6 in skeletal muscle regeneration, Genes Dev., 11, 2040, 10.1101/gad.11.16.2040 · DOI
  24. Fukui, 2011, FGF signaling is required for lens regeneration in Xenopus laevis, Biol. Bull., 221, 137, 10.1086/BBLv221n1p137 · DOI
  25. Galimov, 2016, MicroRNA-29a in adult muscle stem cells controls skeletal muscle regeneration during injury and exercise downstream of fibroblast growth factor-2, Stem Cells, 34, 768, 10.1002/stem.2281 · DOI
  26. Gay, 2013, Fgf9 from dermal gammadelta T cells induces hair follicle neogenesis after wounding, Nat. Med., 19, 916, 10.1038/nm.3181 · DOI
  27. Goldshmit, 2012, Fgf-dependent glial cell bridges facilitate spinal cord regeneration in zebrafish, J. Neurosci., 32, 7477, 10.1523/JNEUROSCI.0758-12.2012 · DOI
  28. Goldshmit, 2014, Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury, Brain Behav., 4, 187, 10.1002/brb3.172 · DOI
  29. Goldshmit, 2015, Decreased anti-regenerative effects after spinal cord injury in spry4-/- mice, Neuroscience, 287, 104, 10.1016/j.neuroscience.2014.12.020 · DOI
  30. Grothe, 2006, Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration--lessons from in vivo studies in mice and rats, Brain Res. Rev., 51, 293, 10.1016/j.brainresrev.2005.12.001 · DOI
  31. Guo, 1996, Keratinocyte growth factor is required for hair development but not for wound healing, Genes Dev., 10, 165, 10.1101/gad.10.2.165 · DOI
  32. Guzy, 2015, Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin, Am. J. Respir. Cell Mol. Biol., 52, 116, 10.1165/rcmb.2014-0184OC · DOI
  33. Guzy, 2017, Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling, J. Biol. Chem., 292, 10364, 10.1074/jbc.M117.791764 · DOI
  34. Gwon, 2006, Lens regeneration in mammals: a review, Surv. Ophthalmol., 51, 51, 10.1016/j.survophthal.2005.11.005 · DOI
  35. Hao, 2016, FGF23 promotes myocardial fibrosis in mice through activation of beta-catenin, Oncotarget, 7, 64649, 10.18632/oncotarget.11623 · DOI
  36. Hayashi, 2004, FGF2 triggers iris-derived lens regeneration in newt eye, Mech. Dev., 121, 519, 10.1016/j.mod.2004.04.010 · DOI
  37. Henry, 2013, Cell signaling pathways in vertebrate lens regeneration, Curr. Top. Microbiol. Immunol., 367, 75, 10.1007/82_2012_289 · DOI
  38. Hochmann, 2012, Fgf signaling is required for photoreceptor maintenance in the adult zebrafish retina, PLoS ONE, 7, e30365, 10.1371/journal.pone.0030365 · DOI · Paper page
  39. Hokuto, 2004, FGF signaling is required for pulmonary homeostasis following hyperoxia, Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L580, 10.1152/ajplung.00278.2003 · DOI
  40. House, 2015, Fibroblast growth factor 2 is an essential cardioprotective factor in a closed-chest model of cardiac ischemia-reperfusion injury, Physiol Rep., 3, e12278, 10.14814/phy2.12278 · DOI
  41. House, 2016, Endothelial fibroblast growth factor receptor signaling is required for vascular remodeling following cardiac ischemia-reperfusion injury, Am. J. Physiol. Heart Circ. Physiol., 310, H559, 10.1152/ajpheart.00758.2015 · DOI
  42. Hu, 2017, FGF-16 protects against adverse cardiac remodeling in the infarct diabetic heart, Am. J. Transl. Res., 9, 1630
  43. Hurley, 2016, Accelerated fracture healing in transgenic mice overexpressing an anabolic isoform of fibroblast growth factor 2, J. Cell. Biochem., 117, 599, 10.1002/jcb.25308 · DOI
  44. Itoh, 2008, Functional evolutionary history of the mouse Fgf gene family, Dev. Dyn., 237, 18, 10.1002/dvdy.21388 · DOI
  45. Jameson, 2002, A role for skin gammadelta T cells in wound repair, Science, 296, 747, 10.1126/science.1069639 · DOI
  46. Ju, 2012, Inhibition of alpha-SMA by the ectodomain of FGFR2c attenuates lung fibrosis, Mol. Med., 18, 992, 10.2119/molmed.2011.00425 · DOI
  47. Jungnickel, 2006, Faster nerve regeneration after sciatic nerve injury in mice over-expressing basic fibroblast growth factor, J. Neurobiol., 66, 940, 10.1002/neu.20265 · DOI
  48. Jungnickel, 2010, Mice lacking basic fibroblast growth factor showed faster sensory recovery, Exp. Neurol., 223, 166, 10.1016/j.expneurol.2009.06.003 · DOI
  49. Kan, 2009, Compensatory growth mechanisms regulated by BMP and FGF signaling mediate liver regeneration in zebrafish after partial hepatectomy, FASEB J., 23, 3516, 10.1096/fj.09-131730 · DOI
  50. Kang, 2014, Astrocyte activation is suppressed in both normal and injured brain by FGF signaling, Proc. Natl. Acad. Sci. USA, 111, E2987, 10.1073/pnas.1320401111 · DOI
  51. Kaslin, 2017, Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration, Development, 144, 1462, 10.1242/dev.144907 · DOI
  52. Kim, 2012, DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling, Nat. Commun., 3, 1296, 10.1038/ncomms2313 · DOI
  53. Klar, 2011, Fibroblast growth factor 10 haploinsufficiency causes chronic obstructive pulmonary disease, J. Med. Genet., 48, 705, 10.1136/jmedgenet-2011-100166 · DOI
  54. Knopf, 2011, Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin, Dev. Cell, 20, 713, 10.1016/j.devcel.2011.04.014 · DOI
  55. Kong, 2014, Fibroblast growth factor 15 deficiency impairs liver regeneration in mice, Am. J. Physiol. Gastrointest. Liver Physiol., 306, G893, 10.1152/ajpgi.00337.2013 · DOI
  56. Kostakopoulou, 1996, ‘Regeneration’ of wing bud stumps of chick embryos and reactivation of Msx-1 and Shh expression in response to FGF-4 and ridge signals, Mech. Dev., 55, 119, 10.1016/0925-4773(95)00492-0 · DOI
  57. Koster, 2006, FGF signaling mediates regeneration of the differentiating cerebellum through repatterning of the anterior hindbrain and reinitiation of neuronal migration, J. Neurosci., 26, 7293, 10.1523/JNEUROSCI.0095-06.2006 · DOI
  58. Kragl, 2009, Cells keep a memory of their tissue origin during axolotl limb regeneration, Nature, 460, 60, 10.1038/nature08152 · DOI
  59. Ku, 2014, The transcriptome of utricle hair cell regeneration in the avian inner ear, J. Neurosci., 34, 3523, 10.1523/JNEUROSCI.2606-13.2014 · DOI
  60. Lee, 2005, Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration, Development, 132, 5173, 10.1242/dev.02101 · DOI
  61. Lee, 2016, Myc and Fgf are required for zebrafish neuromast hair cell regeneration, PLoS ONE, 11, e0157768, 10.1371/journal.pone.0157768 · DOI
  62. Lefaucheur, 1995, Basic fibroblast growth factor promotes in vivo muscle regeneration in murine muscular dystrophy, Neurosci. Lett., 202, 121, 10.1016/0304-3940(95)12223-0 · DOI
  63. Lepilina, 2006, A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration, Cell, 127, 607, 10.1016/j.cell.2006.08.052 · DOI
  64. Lin, 2008, Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration, Dev. Biol., 316, 323, 10.1016/j.ydbio.2008.01.032 · DOI
  65. Love, 2013, Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration, Nat. Cell Biol., 15, 222, 10.1038/ncb2659 · DOI
  66. Makanae, 2014, Co-operative Bmp- and Fgf-signaling inputs convert skin wound healing to limb formation in urodele amphibians, Dev. Biol., 396, 57, 10.1016/j.ydbio.2014.09.021 · DOI
  67. Makanae, 2016, Cooperative inputs of Bmp and Fgf signaling induce tail regeneration in urodele amphibians, Dev. Biol., 410, 45, 10.1016/j.ydbio.2015.12.012 · DOI
  68. Marvaldi, 2015, Enhanced axon outgrowth and improved long-distance axon regeneration in sprouty2 deficient mice, Dev. Neurobiol., 75, 217, 10.1002/dneu.22224 · DOI
  69. Matsumoto, 2013, Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16, Genes Cells, 18, 544, 10.1111/gtc.12055 · DOI
  70. Meyer, 2012, FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin, J. Cell Sci., 125, 5690, 10.1242/jcs.108167 · DOI
  71. Mullen, 1996, Nerve dependency of regeneration: the role of Distal-less and FGF signaling in amphibian limb regeneration, Development, 122, 3487, 10.1242/jcs.108167 · DOI
  72. Nacu, 2016, FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration, Nature, 533, 407, 10.1038/nature17972 · DOI
  73. Numata, 2006, The accelerating effect of histamine on the cutaneous wound-healing process through the action of basic fibroblast growth factor, J. Invest. Dermatol., 126, 1403, 10.1038/sj.jid.5700253 · DOI
  74. Nunes, 2016, Fibroblast growth factors as tissue repair and regeneration therapeutics, PeerJ, 4, e1535, 10.7717/peerj.1535 · DOI
  75. Oladipupo, 2014, Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis, Proc. Natl. Acad. Sci. USA, 111, 13379, 10.1073/pnas.1324235111 · DOI
  76. Ornitz, 2015, The Fibroblast Growth Factor signaling pathway, Wiley Interdiscip. Rev. Dev. Biol., 4, 215, 10.1002/wdev.176 · DOI · Paper page
  77. Ornitz, 2017, Achondroplasia: development, pathogenesis, and therapy, Dev. Dyn., 246, 291, 10.1002/dvdy.24479 · DOI
  78. Ornitz, 2015, Fibroblast growth factor signaling in skeletal development and disease, Genes Dev., 29, 1463, 10.1101/gad.266551.115 · DOI
  79. Ortega, 1998, Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2, Proc. Natl. Acad. Sci. USA, 95, 5672, 10.1073/pnas.95.10.5672 · DOI
  80. Oulion, 2012, Evolution of the FGF gene family, Int. J. Evol. Biol., 2012, 298147
  81. Padrissa-Altés, 2015, Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice, Gut, 64, 1444, 10.1136/gutjnl-2014-307874 · DOI
  82. Pawlikowski, 2017, Regulation of skeletal muscle stem cells by fibroblast growth factors, Dev. Dyn., 246, 359, 10.1002/dvdy.24495 · DOI
  83. Perl, 2009, FGF signaling is required for myofibroblast differentiation during alveolar regeneration, Am. J. Physiol. Lung Cell. Mol. Physiol., 297, L299, 10.1152/ajplung.00008.2009 · DOI · Paper page
  84. Poss, 2000, Roles for Fgf signaling during zebrafish fin regeneration, Dev. Biol., 222, 347, 10.1006/dbio.2000.9722 · DOI
  85. Qin, 2011, FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish, Exp. Eye Res., 93, 726, 10.1016/j.exer.2011.09.003 · DOI
  86. Richardson, 2016, Re-epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals, Development, 143, 2077, 10.1242/dev.130492 · DOI
  87. Rosenkilde, 1996, What mechanisms control neoteny and regulate induced metamorphosis in urodeles?, Int. J. Dev. Biol., 40, 665
  88. Saera-Vila, 2016, Fgf regulates dedifferentiation during skeletal muscle regeneration in adult zebrafish, Cell. Signal., 28, 1196, 10.1016/j.cellsig.2016.06.001 · DOI
  89. Sandoval-Guzmán, 2014, Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species, Cell Stem Cell, 14, 174, 10.1016/j.stem.2013.11.007 · DOI
  90. Seitz, 2011, Poor functional recovery and muscle polyinnervation after facial nerve injury in fibroblast growth factor-2-/- mice can be improved by manual stimulation of denervated vibrissal muscles, Neuroscience, 182, 241, 10.1016/j.neuroscience.2011.03.032 · DOI
  91. Shibata, 2016, Fgf signalling controls diverse aspects of fin regeneration, Development, 143, 2920, 10.1242/dev.140699 · DOI
  92. Song, 2015, Growth factor FGF2 cooperates with interleukin-17 to repair intestinal epithelial damage, Immunity, 43, 488, 10.1016/j.immuni.2015.06.024 · DOI
  93. Sousa-Victor, 2016, Regenerative decline of stem cells in sarcopenia, Mol. Aspects Med., 50, 109, 10.1016/j.mam.2016.02.002 · DOI · Paper page
  94. Spence, 2004, The hedgehog pathway is a modulator of retina regeneration, Development, 131, 4607, 10.1242/dev.01298 · DOI
  95. Spence, 2007, Fibroblast growth factor-hedgehog interdependence during retina regeneration, Dev. Dyn., 236, 1161, 10.1002/dvdy.21115 · DOI
  96. Steiling, 2003, Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration, Oncogene, 22, 4380, 10.1038/sj.onc.1206499 · DOI
  97. Steiling, 2004, Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease, Am. J. Pathol., 165, 1233, 10.1016/S0002-9440(10)63383-4 · DOI
  98. Takase, 2013, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration, Genes Dev., 27, 169, 10.1101/gad.204776.112 · DOI
  99. Takeo, 2013, Wnt activation in nail epithelium couples nail growth to digit regeneration, Nature, 499, 228, 10.1038/nature12214 · DOI
  100. Tanaka, 2016, The molecular and cellular choreography of appendage regeneration, Cell, 165, 1598, 10.1016/j.cell.2016.05.038 · DOI
  101. Tanaka, 2011, The cellular basis for animal regeneration, Dev. Cell, 21, 172, 10.1016/j.devcel.2011.06.016 · DOI
  102. Tanner, 2016, Dysregulated FGF signalling in neoplastic disorders, Semin. Cell Dev. Biol., 53, 126, 10.1016/j.semcdb.2015.10.012 · DOI
  103. Tassi, 2011, Impact of fibroblast growth factor-binding protein-1 expression on angiogenesis and wound healing, Am. J. Pathol., 179, 2220, 10.1016/j.ajpath.2011.07.043 · DOI
  104. Trueb, 2011, Biology of FGFRL1, the fifth fibroblast growth factor receptor, Cell. Mol. Life Sci., 68, 951, 10.1007/s00018-010-0576-3 · DOI
  105. Tzahor, 2017, Cardiac regeneration strategies: Staying young at heart, Science, 356, 1035, 10.1126/science.aam5894 · DOI
  106. Uriarte, 2013, Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice, Gut, 62, 899, 10.1136/gutjnl-2012-302945 · DOI
  107. Virag, 2007, Fibroblast growth factor-2 regulates myocardial infarct repair: effects on cell proliferation, scar contraction, and ventricular function, Am. J. Pathol., 171, 1431, 10.2353/ajpath.2007.070003 · DOI
  108. Volckaert, 2011, Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury, J. Clin. Invest., 121, 4409, 10.1172/JCI58097 · DOI
  109. Wan, 2017, Opposing actions of Fgf8a on Notch signaling distinguish two Muller glial cell populations that contribute to retina growth and regeneration, Cell Rep., 19, 849, 10.1016/j.celrep.2017.04.009 · DOI
  110. Wehling-Henricks, 2016, Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy, Hum. Mol. Genet., 25, 2465, 10.1093/hmg/ddw111 · DOI
  111. Wehner, 2014, Wnt/beta-catenin signaling defines organizing centers that orchestrate growth and differentiation of the regenerating zebrafish caudal fin, Cell Rep., 6, 467, 10.1016/j.celrep.2013.12.036 · DOI
  112. Werner, 2003, Regulation of wound healing by growth factors and cytokines, Physiol. Rev., 83, 835, 10.1152/physrev.00031.2002 · DOI · Paper page
  113. Werner, 1994, The function of KGF in morphogenesis of epithelium and reepithelialization of wounds, Science, 266, 819, 10.1126/science.7973639 · DOI
  114. Whitehead, 2005, Fgf20 is essential for initiating zebrafish fin regeneration, Science, 310, 1957, 10.1126/science.1117637 · DOI
  115. Wietecha, 2011, Sprouty2 downregulates angiogenesis during mouse skin wound healing, Am. J. Physiol. Heart Circ. Physiol., 300, H459, 10.1152/ajpheart.00244.2010 · DOI
  116. Yin, 2008, Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish, Genes Dev., 22, 728, 10.1101/gad.1641808 · DOI
  117. Yokoyama, 2001, FGF-10 stimulates limb regeneration ability in Xenopus laevis, Dev. Biol., 233, 72, 10.1006/dbio.2001.0180 · DOI
  118. Yu, 2000, Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4, J. Biol. Chem., 275, 15482, 10.1074/jbc.275.20.15482 · DOI
  119. Yun, 2010, Fibroblast growth factors: biology, function, and application for tissue regeneration, J. Tissue Eng., 2010, 218142, 10.4061/2010/218142 · DOI
  120. Zhang, 2016, Therapeutic uses of FGFs, Semin. Cell Dev. Biol., 53, 144, 10.1016/j.semcdb.2015.09.007 · DOI
  121. Zhao, 2006, Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway, J. Biol. Chem., 281, 429, 10.1074/jbc.M507440200 · DOI
  122. Zhou, 1998, Fibroblast growth factor 2 control of vascular tone, Nat. Med., 4, 201, 10.1038/nm0298-201 · DOI

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Metadata

Authors
Maddaluno, L., Urwyler, C., & Werner, S.
Affiliations
Institute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Otto-Stern-Weg 7, 8093 Zürich, Switzerland
ORCID
Werner, Sabine
Venue
Development
Publisher
The Company of Biologists
Published
2017-11-15
Volume
144
Issue
22
Pages
4047-4060
ISSN
  • 1477-9129
  • 0950-1991
DOI
10.1242/dev.152587
Cited by
241
References
5
Language
en
Licence
www.biologists.com/user-licence-1-1 (vor, 181 d)
Funders
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (31003A_169204)
  • Eidgenössische Technische Hochschule Zürich
  • Seventh Framework Programme (100011102)

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