The DOI matches its Crossref record.
A quantitative analysis of the effect of excision of the AER from the chick limb-bud
Abstract
The effect of removal of the apical ectodermal ridge from the early chick limb-bud is re-examined using a new quantitative method of analysis of results. The concept of the proximo-distal sequence of laying down of parts is confirmed and evidence is presented that this proceeds as a continuous process, there being a gradual change in the level specified from one cell to another at a more distal level. The results are then interpreted in terms of the ‘progress zone’ model to show that they are both consistent with the model and that they provide an assay for one of its parameters, the rate of change of positional value with time at the tip.
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Citations
Cited by
1 Developmental roles and clinical significance of Hedgehog signaling
McMahon, A. P., Ingham, P. W., & Tabin, C. J. (2003) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)53002-2 · Cited by 772
Molecular Models for Vertebrate Limb Development
Johnson, R. L., & Tabin, C. J. (1997) · Cell · doi:10.1016/s0092-8674(00)80364-5 · Cited by 580
Ohuchi, H., Nakagawa, T., Yamamoto, A., Araga, A., Ohata, T., Ishimaru, Y., Yoshioka, H., Kuwana, T., Nohno, T., Yamasaki, M., et al. (1997) · Development · doi:10.1242/dev.124.11.2235 · Cited by 549
Fgf8 signalling from the AER is essential for normal limb development
Lewandoski, M., Sun, X., & Martin, G. R. (2000) · Nature Genetics · doi:10.1038/82609 · Cited by 451
The development of the paired fins in the zebrafish (Danio rerio).
Grandel, H., & Schulte-Merker, S. (1998) · Mechanisms of Development · doi:10.1016/s0925-4773(98)00176-2 · Cited by 267
Rowe, D. A., Cairns, J. M., & Fallon, J. F. (1982) · Developmental Biology · doi:10.1016/0012-1606(82)90241-x · Cited by 101
Delgado, I., Domínguez‐Frutos, E., Schimmang, T., & Ros, M. A. (2008) · Developmental Dynamics · doi:10.1002/dvdy.21452 · Cited by 13
Metadata
- Authors
- Summerbell, D.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1974-12-01
- Volume
- 32
- Issue
- 3
- Pages
- 651-660
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1904331578
- Cited by
- 374
- References
- 0
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
