The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Integrin traffic
Abstract
Cell adhesion, migration and the maintenance of cell polarity are all processes that depend on the correct targeting of integrins and the dynamic remodelling of integrin-containing adhesion sites. The importance of the endo/exocytic cycle of integrins as a key regulator of these functions is increasingly recognized. Several recent publications have provided mechanistic insight into how integrin traffic is regulated in cells. Increasing evidence suggests that small GTPases such as Arf6 and members of the Rab family control integrin internalization and recycling back to the plasma membrane along microtubules. The fine tuning of these trafficking events seems to be mediated by specific guanine-nucleotide-exchange factors (GEFs) and GTPase-activating proteins (GAPs). In addition, several kinases regulate integrin traffic. The identification of their substrates has demonstrated how these kinases regulate integrin traffic by controlling small GTPases or stabilizing cytoskeletal tracks that are crucial for efficient traffic of integrins to the plasma membrane.
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Cites
Hynes (2002) · doi:10.1016/s0092-8674(02)00971-6 · Cited by 8,606
The phosphoinositide 3-kinase pathway
Cantley, L. C. (2002) · Science · doi:10.1126/science.296.5573.1655 · Cited by 5,621
Bacterial Adhesion and Entry into Host Cells
Pizarro-Cerdá, J., & Cossart, P. (2006) · Cell · doi:10.1016/j.cell.2006.02.012 · Cited by 977 · cited 2×
“Integrins can be used either as primary attachment receptors or as co-receptors in the entry process (Greber, 2002; Marsh and Helenius, 2006; Pizarro-Cerda and Cossart, 2006), and pathogen attachment triggers host-cell signaling pathways that follow binding of the endogenous ligand to integrins…”
BackgroundDi Paolo, G., Pellegrini, L., Letinic, K., Cestra, G., Zoncu, R., Voronov, S., Chang, S., Guo, J., Wenk, M. R., & De Camilli, P. (2002) · Nature · doi:10.1038/nature01147 · Cited by 441
Ras‐activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1
Tall, G. G., Barbieri, M. A., Stahl, P. D., & Horazdovsky, B. F. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00008-9 · Cited by 308
Integrin αvβ3 is a coreceptor for human cytomegalovirus
Wang, X., Huang, D. Y., Huong, S.-M., & Huang, E.-S. (2005) · Nature Medicine · doi:10.1038/nm1236 · Cited by 268
Lovestone, S., Hartley, C. L., Pearce, J., & Anderton, B. H. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00126-1 · Cited by 201
Naranatt, P. P., Akula, S. M., Zien, C. A., Krishnan, H. H., & Chandran, B. (2003) · Journal of Virology · doi:10.1128/jvi.77.2.1524-1539.2003 · Cited by 175
Cited by
Novel functions of vimentin in cell adhesion, migration, and signaling
Ivaska, J., Pallari, H.-M., Nevo, J., & Eriksson, J. E. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.03.040 · Cited by 785
Self-citationIntegrins: masters and slaves of endocytic transport
Caswell, P. T., Vadrevu, S., & Norman, J. C. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2799 · Cited by 460
Caswell, P. T., Chan, M., Lindsay, A. J., McCaffrey, M. W., Boettiger, D., & Norman, J. C. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200804140 · Cited by 388
Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan
Sigismund, S., Confalonieri, S., Ciliberto, A., Polo, S., Scita, G., & Di Fiore, P. P. (2012) · Physiological Reviews · doi:10.1152/physrev.00005.2011 · Cited by 338
Numb Controls Integrin Endocytosis for Directional Cell Migration with aPKC and PAR-3
Nishimura, T., & Kaibuchi, K. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.05.003 · Cited by 335
Metadata
- Authors
- Pellinen, T., & Ivaska, J.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2006-09-15
- Volume
- 119
- Issue
- 18
- Pages
- 3723-3731
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W4211151484
- Cited by
- 187
- References
- 8
- FWCI
- 4.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pellinen, T., & Ivaska, J. (2006). Integrin traffic. Journal of Cell Science. https://doi.org/10.1242/jcs.03216
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
