The DOI matches its Crossref record; 152 of the 155 references it cites were found in a registry or an index.
Muscles and their myokines
Open accessAbstract
Summary: In the past, the role of physical activity as a life-style modulating factor has been considered as that of a tool to balance energy intake. Although it is important to avoid obesity, physical inactivity should be discussed in a much broader context. There is accumulating epidemiological evidence that a physically active life plays an independent role in the protection against type 2 diabetes, cardiovascular diseases, cancer, dementia and even depression. For most of the last century, researchers sought a link between muscle contraction and humoral changes in the form of an ‘exercise factor’, which could be released from skeletal muscle during contraction and mediate some of the exercise-induced metabolic changes in other organs such as the liver and the adipose tissue. We have suggested that cytokines or other peptides that are produced, expressed and released by muscle fibres and exert autocrine, paracrine or endocrine effects should be classified as ‘myokines’. Given that skeletal muscle is the largest organ in the human body, our discovery that contracting skeletal muscle secretes proteins sets a novel paradigm: skeletal muscle is an endocrine organ producing and releasing myokines, which work in a hormone-like fashion, exerting specific endocrine effects on other organs. Other myokines work via paracrine mechanisms, exerting local effects on signalling pathways involved in muscle metabolism. It has been suggested that myokines may contribute to exercise-induced protection against several chronic diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Skeletal muscle contraction during RT triggers the production and release of cytokines such as interleukin (IL) and irisin, which exert effects both locally and in a crosstalk manner with other organs, such as the liver and adipose tissue, to cope with muscle repair, hypertrophy and fuel metabolism [6].”
From β-hydroxy-β -methylbutyrate supplementation benefits the effects of resistance training on body fat reduction via increased irisin expression in white adipose tissue (2021) · cites this paper as [6]
Experimental — accuracy not yet measuredIn the citing paper
“Several risk factors for MS are associated with physical inactivity, including low-grade inflammation and impaired metabolism (403, 404).”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [403]
In the citing paper
“Several risk factors for MS are associated with physical inactivity, including low-grade inflammation and impaired metabolism (403, 404).”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [404]
In the citing paper
“Conversely, prevention of physical inactivity through physical activity improves inflammatory markers by reducing resting CRP, interleukin-6 (IL-6), and tumour necrosis factor-α concentration (403).”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [403]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Immunohistochemical detection of interleukin‐6 in human skeletal muscle fibers following exercise
Penkowa, M., Keller, C., Keller, P., Jauffred, S., & Pedersen, B. K. (2003) · The FASEB Journal · doi:10.1096/fj.03-0311fje · Cited by 157
Self-citationRetractedTHIS ARTICLE HAS BEEN RETRACTED Exercise induces interleukin‐8 expression in human skeletal muscle
Akerstrom, T. C. A., Steensberg, A., Keller, P., Keller, C., Penkowa, M., & Pedersen, B. K. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.077610 · Cited by 130
Self-citationRetractedMatthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873 · cited 2×
“Physical inactivity increases the risk of type 2 diabetes (Tuomilehto et al., 2001), cardiovascular disease (CVD) (Nocon et al.”
BackgroundActual Causes of Death in the United States, 2000
Mokdad, A. H. (2004) · JAMA · doi:10.1001/jama.291.10.1238 · Cited by 5,211
Neurotrophins: Roles in Neuronal Development and Function
Huang, E. J., & Reichardt, L. F. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.677 · Cited by 4,394
Fitness Effects on the Cognitive Function of Older Adults: A Meta-Analytic Study
Colcombe, S., & Kramer, A. F. (2003) · Psychological Science · doi:10.1111/1467-9280.t01-1-01430 · Cited by 3,782
Be smart, exercise your heart: Exercise effects on brain and cognition
Hillman, C. H., Erickson, K. I., & Kramer, A. F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2298 · Cited by 3,563
The anti-inflammatory effect of exercise
Petersen, A. M. W., & Pedersen, B. K. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00164.2004 · Cited by 3,100 · cited 4×
“…low-level inflammation, suggesting that the anti-inflammatory activity induced by regular exercise may exert some of the beneficial health effects of exercise in patients with chronic diseases (reviewed in Wilund, 2007; Petersen and Pedersen, 2005; Petersen and Pedersen, 2006; Pedersen, 2006).”
BackgroundInfluentialSelf-citationRunning enhances neurogenesis, learning, and long-term potentiation in mice
van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904
Flagged first, then by citations
3 of the 155 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 501–600 of 670
Rasoulpour, J., Gharani, H., lorestani, A. Z., Taeid, V., Zoalfaghari, M., Espandar, N., & Shirazd, J. (2022) · مجله علمی پزشکی جندی شاپور · doi:10.32598/jsmj.21.1.2481 · Cited by 1
Cai, C., Ma, Y., Zhang, L., An, Z., Zhou, E., Liu, X., Li, H., Li, W., Li, Z., Li, G., et al. (2024) · British Poultry Science · doi:10.1080/00071668.2024.2410368 · Cited by 1
Mohammadzadeh, N. Z., & Rezaeipour, M. (2025) · BMC Sports Science Medicine and Rehabilitation · doi:10.1186/s13102-025-01349-2 · Cited by 1
Cruz‐Montecinos, C., Calatayud, J., Núñez-Cortés, R., Ogrezeanu, D. C., Tur‐Boned, A., Xiao, F., Soto, V., Andersen, L. L., & Maas, H. (2026) · Seminars in Thrombosis and Hemostasis · doi:10.1055/a-2788-1715 · Cited by 1
Chen, X. P., Wang, Y., Wu, J., He, Y., Chen, H., Ye, H., & Liu, J. (2026) · Journal of Diabetes Research · doi:10.1155/jdr/6450867 · Cited by 1
García-Miralles, N., Martínez‐García, I., Marcilla-Toribio, I., Herreros-Solano, A., Fernández‐Bravo‐Rodrigo, J., Patiño‐Cardona, S., Moreno-Charco, E., Ortega-Armiñana, A. M., Gregori-Navarro, M., & Pascual‐Morena, C. (2026) · Healthcare · doi:10.3390/healthcare14131998 · Cited by 1
Otağ, A., Deveci, D., Otağ, İ., & Koşar, İ. (2013) · Global Journal of Medical Research · Cited by 1
Fundamentals of Diet, Exercise, and Behavior Modification
Blackstone, R. P. (2016) · Springer eBooks · doi:10.1007/978-3-319-39409-1_8 · Cited by 1
Bengtsson-Lindberg, M. E., Wilke, L., Vestberg, S., Jacobsson, H., & Wisén, A. G. M. (2017) · International Journal of Physical Therapy & Rehabilitation · doi:10.15344/2455-7498/2017/138
Jak mięśnie komunikują się z innymi narządami i co z tego wynika?
Ziemann, E. (2021) · Kosmos · doi:10.36921/kos.2020_2707 · Cited by 1
Demirci, B. G., & Karakan, M. Ş. (2024) · The European Research Journal · doi:10.18621/eurj.1404126 · Cited by 1
IL-15 : A NOVEL REGULATOR OF LIPOLYSIS IN HUMANS?
Pierce, J. R. (2014) · Cited by 1
Exercise training-induced changes in inflammatory mediators and heat shock proteins in canoeists
Morawin, B., & al., E. (2018) · Annals of Research in Sport and Physical Activity · doi:10.14195/2182-7087_ex2018_57 · Cited by 1
Zhang, X., Xie, M., Yan, Y., Wu, Y., & Xu, J. (2011) · Journal of Exercise Science & Fitness · doi:10.1016/s1728-869x(12)60008-2 · Cited by 1
Envejecimiento, masa muscular y entrenamiento de la fuerza: una revisión
Franco, S. A. A., Villada, F. A. P., & Fernández, J. A. P. (2014) · Lúdica Pedagógica · doi:10.17227/01214128.19ludica47.56 · Cited by 1
Intensidade de Exercício Físico e Imunomodulação: Impactos em Infecções das Vias Aéreas
Lopes, D. P. S., Muniz, I. P. R., & da Silva, R. A. A. (2016) · Saúde e Pesquisa · doi:10.17765/1983-1870.2016v9n1p175-186 · Cited by 1
Leite, M. M., Silva, A. D. O., Vieira, V. B., Funghetto, S. S., & de Farias, D. L. (2018) · Programa de Iniciação Científica - PIC/UniCEUB - Relatórios de Pesquisa · doi:10.5102/pic.n1.2015.5475 · Cited by 1
Krentz, A. J., & Bédossa, P. (2019) · Springer eBooks · doi:10.1007/978-3-030-11748-1_10 · Cited by 1
Muskelaktivität – Muskelinaktivität: anti-nozizeptive oder pro-nozizeptive Körperstrukur
Laube, W. (2020) · Springer eBooks · doi:10.1007/978-3-662-60512-7_5 · Cited by 1
Pahmeier, I. (2019) · Springer eBooks · doi:10.1007/978-3-662-53384-0_13-1 · Cited by 1
Association of Sarcopenia with Heart Rate Variability
Ji, J.-M., Koh, H.-M., Jang, J.-Y., Moon, J.-S., Bak, H.-R., Jang, H.-J., Lee, A.-N., & Ko, N. G. (2022) · Korean Journal of Family Practice · doi:10.21215/kjfp.2022.12.5.311 · Cited by 1
Beshay, E. V. N., & Mostafa, O. (2023) · Journal of the Egyptian Society of Parasitology · doi:10.21608/jesp.2023.312176 · Cited by 1
Dunford, E. C. (2016) · YorkSpace (York University) · Cited by 1
Bone markers and cytokines in response to low-impact, high-intensity exercise
Mezil, Y. (2014) · Brock University Digital Repository (Brock University)
Adipose Tissue and Skeletal Muscle Plasticity in Obesity and Metabolic Disease
Ukropec, J., & Ukropcov, B. (2012) · InTech eBooks · doi:10.5772/28506
Exercise, Nutrition, and Inflammation
Kraakman, M. J., Whitham, M., & Febbraio, M. A. (2013) · Wiley eBooks · doi:10.1002/9781118692318.ch38
Schweitzer, G. G. (2012) · Deep Blue (University of Michigan)
Tupper, S. (2012) · University Library - University of Saskatchewan (University of Saskatchewan)
The effect of quercetin on exercise induced cytokine response in trained cyclists
Chou, T. (2012) · Texas ScholarWorks (Texas Digital Library)
The Year in S trength Science 2013
Sullivan, J. (2013)
PHARMACOLOGY AND CELL METABOLISM Interleukin-15 and Other Myokines in Chronic Alcoholics
González‐Reimers, E., Fernández-Rodríguez, C. M., Santolaria-Fernández, F. J., José, M., Martín‐González, C., Gómez-Rodrı́guez, M. A., & Rodrı́guez-Gaspar, M. (2011)
Heinrich, J., & München, L.-M.-U. (2012)
Huntsman, H. D. (2014) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
Salisbury, D. L. (2014) · University of Minnesota Digital Conservancy (University of Minnesota)
Do Probiotics Protect Against the Deleterious Effects of a High-Fat Diet?
Fundaro, G. (2014) · VTechWorks (Virginia Tech)
Inflammation and body composition in over- and undernutrition: Overweight and cancer cachexia
Wesseltoft-Rao, N. (2015) · NORA - Norwegian Open Research Archives
Gorbach, T. V., & Baranova, M. S. (2015) · Pathologia · doi:10.14739/2310-1237.2015.2.50989
[Drug treatment of cholestatic liver diseases].
Reichen, J. (1992) · PubMed
Skjølsvik, A. M. (2012) · NORA - Norwegian Open Research Archives
Effekt av trening in vivo og in vitro på humane skjelettmuskelceller i kultur
Løvsletten, N. G. (2015) · NORA - Norwegian Open Research Archives
AGING, MUSCLE MASS AND STRENGTH TRAINING: A REVIEW
Adolfo, S., Franco, A., Alonso, F., Villada, P., & Fernández, J. A. D. P. (2014)
The Effects of Interleukin-10 on Skeletal Muscle Insulin Resistance and Myogenesis
Dağdeviren, S. (2016) · eScholarship@UMassChan · doi:10.13028/m2qp42 · Cited by 1
Skeletal muscle fatigue: Investigating the role of cytokines, ROS and mitochondrial function.
Earl, K. E. (2016) · University of Liverpool · doi:10.17638/03001668
Graduate School of Biosphere Science
Suidasari, S. (2016)
Damas, F. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.39.2017.tde-11102017-092823
La funzione endocrina del muscolo scheletrico
Marampon, F., & Crescioli, C. (2018) · L Endocrinologo · doi:10.1007/s40619-017-0381-4
Völker, K. (2018) · Springer eBooks · doi:10.1007/978-3-662-56539-1_16
Magalhães, D. M., & al., E. (2018) · Annals of Research in Sport and Physical Activity · doi:10.14195/2182-7087_ex2018_55
de Oliveira, C. E. P. (2018) · doi:10.18002/10612/7958
Un programa de ejercicio de 20 semanas mejora marcadores de estatus cognitivo, inflamatorios y metab
Pisabarro, R., Gutiérrez, M., Orellano, P., Charamelo, A., Lladó, N., Kamaid, A., Mattiozzi, A., & Mazza, M. (2017) · Revista Médica del Uruguay · doi:10.29193/rmu.34.3.2
Response of Interleukins to Resistance Exercise
Vasconcelos, E. D. S. (2018) · Virology & Immunology Journal · doi:10.23880/vij-16000141
Franco, S. A. A. (2014) · Buleria (Universidad de León) · doi:10.18002/10612/3671
Paracrine Modulation of Mechanotransduction
Huang, J., Wang, Z., Brotto, L. S., Varanasi, V. G., Mo, C., & Brotto, M. A. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11214-0
Wellendorf, J. (2018) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-6736
Physiological and molecular aspects of ovarian follicular developmental competence in sows
Costermans, N. G. J. (2020) · doi:10.18174/502793
Kilroy, E. A. (2020) · DigitalCommons (California Polytechnic State University)
Association between Relative Handgrip Strength and C-Reactive Protein in Adults
Park, D. Y., Kang, M. S., Park, J. Y., Kim, M. K., Choi, B. Y., & Kim, Y. S. (2020) · The Korean Journal of Sports Medicine · doi:10.5763/kjsm.2020.38.3.164
Fuentes, B., & Alejandro, D. (2020)
Kang, S., Park, I., & Lim, S. (2020) · doi:10.21203/rs.3.rs-16256/v1
Epperlein, H., Wichmann, K., & Deußen, A. (2021) · Springer eBooks · doi:10.1007/978-3-662-62593-4_2
Polimorfismo e níveis solúveis de HLA-G em fisiculturistas
Fernandes, T. M. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.109.2020.tde-21072020-143210
Effect of Remote Ischemic Conditioning in Hemorrhagic Shock/Resuscitation
Leung, C. H. (2019) · TSpace (University of Toronto)
Shoulah, A. A., Khalil, M. A., Nan, M. M., & Mofeed, A. M. A. E. (2021) · Benha Journal of Applied Sciences · doi:10.21608/bjas.2021.169153
Neuroanatomie und Neurophysiologie der Motorik – Wechselwirkungen des sensomotorischen Systems
Laube, W. (2021) · Springer eBooks · doi:10.1007/978-3-662-60493-9_2
Microvascular cover in the lower limb
Arnež, Z. M. (2021) · doi:10.1093/med/9780199682874.003.0054
Daniels, D. (2021) · ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe – University of Galway) · doi:10.13025/17983
How to be physically active while social distancing? You need to exercise!
Luz, L. G. D. O., Fortes, M. D. S. R., & Neto, G. D. A. M. (2021) · Revista de Educação Física / Journal of Physical Education · doi:10.37310/ref.v90i2.2766
Efectos de la cirugía mayor abdominal, sobre la condición física y la respuesta inflamatoria
Mejía, Ó. A. A., & Andrés, Ó. (2021)
Pilat, C. (2015) · Elsevier eBooks · doi:10.1016/b978-3-437-24255-7.00008-6
Analysis of the immune response in padel
Pía, C., Otín, C., Páez, L., & De, L. F. H. (2021) · Fizicko vaspitanje i sport kroz vekove · doi:10.5937/spes2102134c
Silva, S. B., Sampaio, K. H., Costa, S. P., Domingos, T. E., da Cruz, T. M. M., Rodrigues, C. M., Costa, K. B., dos Santos, J. M., Lage, V. K. D. S., Gaiad, T. P., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1279791/v1
(2014) · CRC Press eBooks · doi:10.1201/b16783-3
Pathogenese chronisch degenerativer Erkrankungen
Laube, W. (2022) · Springer eBooks · doi:10.1007/978-3-662-63846-0_5
Primär chronisch degenerative Erkrankungen: ein Lifestyle-Produkt
Laube, W. (2022) · Springer eBooks · doi:10.1007/978-3-662-63846-0_1 · Cited by 1
Ilich, J. Z., Kelly, O. J., Gilman, J. C., Cvijetić, S., & Boschiero, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-820088-9.00014-7
Internationale Studienergebnisse
(2021) · physiopraxis · doi:10.1055/a-1255-6791
Novel Therapeutic Strategy for the Prevention of Bone Fractures
Hamrick, M. W. (2014) · Defense Technical Information Center (DTIC) · doi:10.21236/ada614236
Pilat, C., & Mooren, F. C. (2015) · Elsevier eBooks · doi:10.1016/b978-3-437-24275-5.00001-4
Георгиевна, Б. И., Ovchinina, N. G., Protopopov, V. A., Sekunov, A. V., & Shalagina, M. N. (2020) · doi:10.21203/rs.3.rs-111015/v1
Pahmeier, I. (2022) · Springer eBooks · doi:10.1007/978-3-662-53404-5_13
Evidence-based non-pharmacological treatment of inflammatory rheumatic diseases
Vlak, T. (2022) · Reumatizam · doi:10.33004/reumatizam-supp-69-1-1
ANALYSIS OF THE ACUTE INFLAMMATORY RESPONSE PRODUCED DURING THE GAME OF PADEL
Suárez, M., Suárez, D. M. M., Zayas, M. Á. O., Ángel, M., Otín, C. C., & de la Fuente, F. P. (2021) · SPORT I ZDRAVLJE · doi:10.7251/sizen2101082s
ANALIZA AKUTNOG INFLAMATORNOG ODGOVORA KOJI NASTAJE TOKOM BAVLJENJA PADELOM
Suárez, M., Suárez, D. M. M., Zayas, M. Á. O., Ángel, M., Otín, C. C., & de la Fuente, F. P. (2021) · SPORT I ZDRAVLJE · doi:10.7251/siz2101017s
СВОБОДНЫЕ РАДИКАЛЫ И АНТИОКСИДАНТЫ ПРИ МЫШЕЧНОЙ ДЕЯТЕЛЬНОСТИ
Hajiyev, A. M., & Hasanova, A. K. (2021) · Scientific News of Academy of Physical Education and Sport · doi:10.28942/ssj.v2i3.252
Reaktion und Anpassung an sportliche Beanspruchung
Neumann, G. (2022) · Elsevier eBooks · doi:10.1016/b978-3-437-24093-5.00001-9
Introduction to Immune-Mediated Myopathies
Gaspar, B. L. (2023) · Springer eBooks · doi:10.1007/978-981-19-8421-1_1
Farghaly, M. (2023) · المجلة الجنائية القومية · doi:10.21608/ncj.2023.302314
Myokines, Measurement, and Technical Considerations
Willis, C. R. G., Deane, C. S., & Etheridge, T. (2023) · Neuromethods · doi:10.1007/978-1-0716-3315-1_12
Gewebe vermitteln mit genetischen Informationen ihren Funktionszustand
Laube, W. (2023) · Springer eBooks · doi:10.1007/978-3-662-67753-7_10
Miyokin / Sitokinlerin Kas Hipertrofisindeki Rolü
DÜNDAR, S. T., & VAROL, S. R. (2023) · doi:10.59287/spbgy.949
Causal association of sarcopenia with brain cortical structure: A Mendelian randomization studyPreprint
Zhan, Y., Zhang, Z., Lin, S., Du, B., Wu, J. C., & Xu, H. (2023) · Research Square · doi:10.21203/rs.3.rs-3680436/v1
Metadata
- Authors
- Pedersen, B. K.
- Affiliations
- Rigshospitalet (DK)
- Corresponding author
- Pedersen, Bente Klarlund
- Venue
- Journal of Experimental Biology
- Publisher
- The Company of Biologists
- Published
- 2011-01-15
- Volume
- 214
- Issue
- 2
- Pages
- 337-346
- ISSN
- 0022-0949 (ISSN-L)
- 1477-9145
- OpenAlex
- W2033127864
- Cited by
- 668
- References
- 155
- Citations by year
- 2026: 19 · 2025: 26 · 2024: 55 · 2023: 34 · 2022: 46 · 2021: 58 · 2020: 59 · 2019: 39 · 2018: 49 · 2017: 50 · 2016: 46 · 2015: 45 · 2014: 43 · 2013: 46 · 2012: 41
- FWCI
- 32.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Experimental Biology (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
- Funders
- Strategiske Forskningsråd (09-067009 and 09-075724, 09–067009, 09 – 075724)
- Sundhed og Sygdom, Det Frie Forskningsråd
- National Research Foundation
- Danmarks Grundforskningsfond (# 02-512-55, 09-067009, 09-075724)
- Ministério da Ciência, Tecnologia e Inovação
- Medical Research Council
- Topics
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- myokines, skeletal muscle, physical activity, paracrine signaling, autocrine signaling, exercise-induced metabolic changes, type 2 diabetes, cardiovascular disease, cancer, dementia, depression, physical inactivity, obesity
- MeSH terms
- Adipose Tissue, Animals, Cardiovascular Diseases, Chronic Disease, Diabetes Mellitus, Type 2, Humans, Motor Activity, Neoplasms, Exercise, Interleukin-6, Cytokines, Muscle, Skeletal, Neurodegenerative Diseases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
