Cited by 25Nanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryPhotodynamic Therapy Research Studies

PEGylated Polymer Micelle-based Nitric Oxide (NO) Photodonor with NO-mediated Antitumor Activity

Kanayama, Naoki, Yamaguchi, Kazuhiro, Nagasaki, Yukio·2010·Chemistry Letters

Abstract

PEGylated polymer micelles containing 4-nitro-3-trifluoromethylphenyl units within the core moiety were prepared, and their phototriggered nitric oxide (NO)-generating ability was confirmed by electron spin resonance (ESR) spin-trapping and the Griess method. These micelles were found to be capable of delivering exogenous NO into tumor cells in a photocontrolled manner and showed an NO-mediated antitumor effect, indicating the usability of this molecular system in NO-based tumor therapy.

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Crossref · 10.1246/cl.2010.1008

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21 of 21 references verified0 citation errors · 0 not checkable

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Authors
Kanayama, N., Yamaguchi, K., & Nagasaki, Y.
Affiliations
University of Tsukuba (JP)
Venue
Chemistry Letters
Published
2010-08-14
Volume
39
Issue
9
Pages
1008-1009
ISSN
  • 0366-7022 (ISSN-L)
  • 1348-0715
OpenAlex
W2039743179
Cited by
25
References
21
Citations by year
2026: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 4 · 2013: 3 · 2012: 1
FWCI
1.32
Type
journal article
Language
en
Open access
closed
Locations
Chemistry Letters (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
Keywords
nitric oxide production, anticancer activity

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