Variable Duration of Decaffeinated Green Tea Extract Ingestion on Exercise Metabolism
Abstract
PURPOSE: The aim of this study was to investigate if the duration of decaffeinated green tea extract (dGTE) ingestion plays a role in augmenting fat oxidation rates during moderate-intensity exercise. METHODS: In a crossover, placebo-controlled design, 19 healthy males (mean ± SD; age = 21 ± 2 yr, weight = 75.0 ± 7.0 kg, body mass index = 23.2 ± 2.2 kg·m, maximal oxygen consumption [V˙O2max] = 55.4 ± 4.6 mL·kg·min) ingested dGTE and placebo (PLA) for 28 d, separated by a 28-d washout period. On the first day (dGTE 1 or PLA 1) and after 7 d (dGTE 7 or PLA 7) and 28 d (dGTE 28 or PLA 28), participants completed a 30-min cycle exercise bout (50% Wmax), 2 h after ingestion. Indirect calorimetry was used to calculate rates of whole-body fat and carbohydrate oxidation during exercise. Blood samples were collected at rest and during exercise for analysis of plasma fatty acids, glycerol, and epigallocatechin gallate. RESULTS: The ingestion of dGTE did not significantly change whole-body fat oxidation rates during exercise on day 1, 7, or 28 compared with PLA. There were also no changes in plasma concentrations of fatty acids and glycerol at rest and during exercise as a result of dGTE ingestion at any time point compared with PLA. Plasma epigallocatechin gallate concentrations, immediately before the exercise bout, in the three dGTE trials were elevated compared with PLA but not different between 1, 7, and 28 d. CONCLUSION: In contrast to previous reports, we found that the duration of dGTE ingestion had no effect on whole-body fat oxidation rates or fat metabolism-related blood metabolites during exercise in physically active healthy males.
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Green tea extracts increase fat oxidation and performance in mice, but in humans these effects were not found after 7-28 days of green tea extract supplementation.
“For example, while green tea extracts (containing the active component epicatechin and epigallocatechin gallate) have been shown to increase fat oxidation and performance in mice [94], in humans, these effects were not found [95] after 7–28 days of green tea extract supplementation.”
From Periodized Nutrition for Athletes (2017) · cites this paper as [95]
Cites
Sample size of 12 per group rule of thumb for a pilot study
Julious, S. A. (2005) · Pharmaceutical Statistics · doi:10.1002/pst.185 · Cited by 3,068 · see citing works
Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
Holloszy, J. O., & Coyle, E. F. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.56.4.831 · Cited by 1,985 · see citing works
Romijn, J. A., Coyle, E. F., Sidossis, L. S., Gastaldelli, A., Horowitz, J. F., Endert, E., & Wolfe, R. R. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e380 · Cited by 1,747 · see citing works
Biochemical Adaptations in Muscle
Holloszy, J. O. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96046-1 · Cited by 1,517 · see citing works
Dulloo, A. G., Duret, C., Rohrer, D., Girardier, L., Mensi, N., Fathi, M., Chantre, P., & Vandermander, J. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.6.1040 · Cited by 925 · see citing works
The effects of increasing exercise intensity on muscle fuel utilisation in humans
van Loon, L. J. C., Greenhaff, P. L., Constantin‐Teodosiu, D., Saris, W. H. M., & Wagenmakers, A. J. M. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00295.x · Cited by 897 · see citing works
Variability of Aerobic Performance in the Laboratory and Its Physiologic Correlates
Kuipers, H., VERSTAPPEN, F. T. J., KEIZER, H. A., Geurten, P., & van Kranenburg, G. (1985) · International Journal of Sports Medicine · doi:10.1055/s-2008-1025839 · Cited by 884 · see citing works
Measurement of substrate oxidation during exercise by means of gas exchange measurements
Jeukendrup, A. E., & Wallis, G. A. (2005) · International Journal of Sports Medicine · doi:10.1055/s-2004-830512 · Cited by 799 · see citing works
Self-citationScharbert, S., & Hofmann, T. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf050294d · Cited by 600 · see citing works
Determination of the exercise intensity that elicits maximal fat oxidation
ACHTEN, J., GLEESON, M., & JEUKENDRUP, A. E. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200201000-00015 · Cited by 551 · cited 3× · see citing works
“At low to moderate exercise intensities (up to ~60% V ̇O2max) fat oxidation increases in absolute terms (g∙min) (1, 23, 31).”
BackgroundSelf-citationTotal Phenol, Catechin, and Caffeine Contents of Teas Commonly Consumed in the United Kingdom
Khokhar, S., & Magnusdottir, S. G. M. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010153l · Cited by 533 · see citing works
Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study
Venables, M. C., Achten, J., & Jeukendrup, A. E. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00662.2003 · Cited by 503 · see citing works
Self-citationChow, H. ‐. S., Cai, Y., Alberts, D. S., Hakim, I. A., Dorr, R. T., Shahi, F., Crowell, J. A., Yang, C. S., & Hara, Y. (2001) · PubMed · Cited by 419 · see citing works
Chow, H.-H. S., Hakim, I. A., Vining, D. R., Crowell, J. A., Ranger-Moore, J., Chew, W. M., Celaya, C. A., Rodney, S. R., Hara, Y., & Alberts, D. S. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2549 · Cited by 400 · see citing works
Exercise training increases lipid metabolism gene expression in human skeletal muscle
Tunstall, R. J., Mehan, K. A., Wadley, G. D., Collier, G. R., Bonen, A., Hargreaves, M., & Cameron-Smith, D. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00475.2001 · Cited by 292 · see citing works
Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans
Venables, M., Hulston, C. J., Cox, H. R., & Jeukendrup, A. E. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.3.778 · Cited by 281 · see citing works
Self-citationMaximal fat oxidation during exercise in trained men
(2003) · International Journal of Sports Medicine · doi:10.1055/s-2003-43265 · Cited by 253 · cited 1× · see citing works
“Higher rates of absolute fat oxidation have been found in trained compared with untrained/ sedentary populations (2, 20).”
BackgroundSelf-citationLee, M.-S., Kim, C., & Kim, Y. (2009) · Annals of Nutrition and Metabolism · doi:10.1159/000214834 · Cited by 215 · see citing works
Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice
Murase, T., Haramizu, S., Shimotoyodome, A., Nagasawa, A., & Tokimitsu, I. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00693.2004 · Cited by 210 · see citing works
Murase, T., Haramizu, S., Shimotoyodome, A., Tokimitsu, I., & Hase, T. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00752.2005 · Cited by 209 · see citing works
Bérubé-Parent, S., Pelletier, C., Doré, J., & Tremblay, A. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20051502 · Cited by 202 · see citing works
Oolong Tea Increases Metabolic Rate and Fat Oxidation in Men
Rumpler, W. V., Seale, J., Clevidence, B. A., Judd, J. T., Wiley, E., Yamamoto, S., Komatsu, T., Sawaki, T., Ishikura, Y., & Hosoda, K. (2001) · Journal of Nutrition · doi:10.1093/jn/131.11.2848 · Cited by 199 · see citing works
Health-promoting effects of green tea
Suzuki, Y., Miyoshi, N., & Isemura, M. (2012) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.88.88 · Cited by 154 · see citing works
Nordby, P., Saltin, B., & Helge, J. W. (2006) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2005.00480.x · Cited by 148 · see citing works
Sae‐tan, S., Grove, K. A., Kennett, M. J., & Lambert, J. D. (2011) · Food & Function · doi:10.1039/c0fo00155d · Cited by 119 · see citing works
Exercise and Green Tea Extract Stimulate Fat Oxidation and Prevent Obesity in Mice
Shimotoyodome, A., Haramizu, S., Inaba, M., Murase, T., & Tokimitsu, I. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000178062.66981.a8 · Cited by 100 · see citing works
Hodgson, A. B., Randell, R. K., & Jeukendrup, A. E. (2013) · Advances in Nutrition · doi:10.3945/an.112.003269 · Cited by 89 · see citing works
Self-citationThielecke, F., Rahn, G., Böhnke, J., Adams, F., Birkenfeld, A. L., Jordan, J., & Boschmann, M. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.47 · Cited by 75 · see citing works
Gregersen, N. T., Bitz, C., Krog-Mikkelsen, I., Hels, O. H., Kovacs, E. M. R., Rycroft, J. A., Frandsen, E., Mela, D. J., & Astrup, A. V. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509371779 · Cited by 61 · see citing works
Self-citationEffects of Combination of Regular Exercise and Tea Catechins Intake on Energy Expenditure in Humans
Ota, N., Soga, S., Shimotoyodome, A., Haramizu, S., Inaba, M., Murase, T., & Tokimitsu, I. (2005) · Eisei kagaku · doi:10.1248/jhs.51.233 · Cited by 60 · see citing works
Eichenberger, P. A., Colombani, P. C., & Mettler, S. (2009) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.79.1.24 · Cited by 58 · see citing works
Ichinose, T., Nomura, S., Someya, Y., Akimoto, S., Tachiyashiki, K., & Imaizumi, K. (2010) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2009.01077.x · Cited by 57 · see citing works
No Effect of 1 or 7 d of Green Tea Extract Ingestion on Fat Oxidation during Exercise
Randell, R. K., Hodgson, A. B., LOTITO, S. B., Jacobs, D. M., Boon, N., Mela, D. J., & Jeukendrup, A. E. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31827dd9d4 · Cited by 26 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Periodized Nutrition for Athletes
Jeukendrup, A. E. (2017) · Sports Medicine · doi:10.1007/s40279-017-0694-2 · Cited by 299 · see citing works
Self-citationRoberts, J., Roberts, M. G., Tarpey, M. D., Weekes, J. C., & Thomas, C. H. (2015) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-014-0062-7 · Cited by 66 · see citing works
Kapoor, M. P., Sugita, M., Fukuzawa, Y., & Ōkubo, T. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.10.013 · Cited by 53 · see citing works
Sugita, M., Kapoor, M. P., Nishimura, A., & Ōkubo, T. (2015) · Nutrition · doi:10.1016/j.nut.2015.09.005 · Cited by 51 · see citing works
Factors Influencing Substrate Oxidation During Submaximal Cycling: A Modelling Analysis
Rothschild, J. A., Kilding, A. E., Stewart, T., & Plews, D. J. (2022) · Sports Medicine · doi:10.1007/s40279-022-01727-7 · Cited by 46 · see citing works
Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis
Craig, D. M., Ashcroft, S. P., Belew, M. Y., Stocks, B., Currell, K., Baar, K., & Philp, A. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00296 · Cited by 45 · see citing works
Roberts, J., Willmott, A. G. B., Beasley, L., Boal, M., Davies, R., Martin, L., Chichger, H., Gautam, L., & Coso, J. D. (2021) · Nutrients · doi:10.3390/nu13030764 · Cited by 40 · see citing works
Silkworm pupae powder ingestion increases fat metabolism in swim-trained rats
Ryu, S. P. (2014) · Physical Activity and Nutrition · doi:10.5717/jenb.2014.18.2.141 · Cited by 31 · see citing works
Polyphenol supplementation boosts aerobic endurance in athletes: systematic review
Cao, G., Zuo, J., Wu, B., & Wu, Y. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1369174 · Cited by 24 · see citing works
Metabolic Response to Decaffeinated Green Tea Extract during Rest and Moderate-Intensity Exercise
Jacobs, D. M., Hodgson, A. B., Randell, R. K., Mahabir-Jagessar-T, K., Garczarek, U., Jeukendrup, A. E., Mela, D. J., & LOTITO, S. B. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf502764r · Cited by 20 · see citing works
Self-citationMartin, B. J., MacInnis, M. J., Gillen, J. B., Skelly, L. E., & Gibala, M. J. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0169 · Cited by 16 · see citing works
Martin, B. J., McGlory, C., MacInnis, M. J., Allison, M. K., Phillips, S. M., & Gibala, M. J. (2016) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00657.2016 · Cited by 9 · see citing works
Effects of green tea catechins and exercise training on body composition parameters
Braschi, A., Presti, R. L., Abrignani, M. G., Abrignani, V., & Traina, M. (2022) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2022.2150152 · Cited by 8 · see citing works
Blicher, S., Bartholomae, E. M., & Kressler, J. (2018) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2018.09.007 · Cited by 8 · see citing works
Polyphenols and Exercise in Mitochondrial Biogenesis: Focus on Age-Related CNS Disorders
Tu, J. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05121-y · Cited by 10 · see citing works
Mashhadi, M. R., & Hosseini, S. R. A. (2022) · Sport Sciences for Health · doi:10.1007/s11332-022-00955-8 · Cited by 7 · see citing works
Churm, R., Williams, L. M., Dunseath, G. J., Prior, S. L., & Bracken, R. M. (2023) · European Journal of Nutrition · doi:10.1007/s00394-023-03092-1 · Cited by 7 · see citing works
[EFFECTS OF GREEN TEA ON THE NUTRITIONAL STATUS OF THE EXERCISE].
Pérez, E. A., & García-Galbis, M. R. (2015) · PubMed · doi:10.3305/nh.2015.32.4.9306 · Cited by 2 · see citing works
EFEITOS DA SUPLEMENTAÇÃO DE CHÁ VERDE SOBRE A PERDA DE PESO
Santana, L. S., Silva, M. O., Feitosa, L. F., & do Nascimento, M. V. S. (2014) · Caderno de Graduação - Ciências Biológicas e da Saúde - UNIT - SERGIPE
A ATUAÇÃO DO CHÁ VERDE NO ESTRESSE OXIDATIVO EM INDIVÍDUOS OBESOS FISICAMENTE ATIVOS
Fernandes, S. G. A., NOBRE, F. M., MENDES, A. S., OLIVEIRA, T. A. C. D., & NASCIMENTO, A. F. M. (2025) · Congresso Brasileiro de Doenças Crônicas · doi:10.51161/iv-cronics/53753
Shirkoohi, N. M., Amin, H., Zebari, S. M. S., Naeini, F., Karimi, P., Shab‐Bidar, S., & Djafarian, K. (2025) · Sport Sciences for Health · doi:10.1007/s11332-025-01475-x
Khalilkhaneh, A. H., Bideshki, M. V., Zebari, S. M. S., Talebi, S., Mohajerani, A., & Djafarian, K. (2026) · Nutrition Reviews · doi:10.1093/nutrit/nuag025
- Authors
- RANDELL, R. K., HODGSON, A. B., LOTITO, S. B., JACOBS, D. M., ROWSON, M., MELA, D. J., & JEUKENDRUP, A. E.
- Affiliations
- Unilever Research and Development Vlaardingen (NL)
- University of Birmingham (GB)
- Unilever (United Kingdom) (GB)
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2014-06
- Volume
- 46
- Issue
- 6
- Pages
- 1185-1193
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W2139594491
- Cited by
- 22
- References
- 33
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 1 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 4 · 2014: 3
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Tea Polyphenols and Effects
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- fat oxidation, exercise metabolism, duration of supplementation, epigallocatechin gallate, plasma fatty acids, plasma glycerol, carbohydrate oxidation, moderate-intensity exercise, healthy men
- MeSH terms
- Adipose Tissue, Adult, Catechin, Energy Metabolism, Fatty Acids, Glycerol, Humans, Male, Oxidation-Reduction, Plant Extracts, Tea, Exercise, Cross-Over Studies, Camellia sinensis, Carbohydrate Metabolism
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