The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Stress response of rats to handling and experimental procedures
Abstract
The effects were observed of moving male, adult Han:Sprague rats in their cages or of exposure to ether for 1 min on the plasma concentration profiles of 25 blood characteristics linked with stress and shock reactions. 5 min after the stress serum prolactin, corticosterone, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, triiodothyronine and thyroxin levels were elevated 150-500% compared with those in blood collected within 100 s of entering the animal room. Heart rate (telemetrically recorded), packed cell volume,, haemoglobin and plasma protein content were 10-20% elevated 2-10 min after cage movement or 2-20 min after ether confrontation over those of controls sampled within 50 s, indicating circulatory and microcirculatory shock reactions. Serum glucose, pyruvate and lactate concentrations rose by 20-100% 1-5 min after cage movement and 1-15 min after ether exposure. Phosphate, calcium, urea, apartate and alanine transferases, alkaline phosphalase and leucine arylamidase were not altered significantly by either stressor, while potassium and bound glycerol fell for 1 min and 5-20 min respectively. The presence of a familiar animal attendant working in the room without touching the cages did not markedly affect the blood characteristics being studied.
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Cites
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NEILL, J. D. (1970) · Endocrinology · doi:10.1210/endo-87-6-1192 · Cited by 229
Hormones and Resistance: Part 1 and Part 2
Selye, H. (1971) · Springer eBooks · doi:10.1007/978-3-642-65192-2 · Cited by 220
Rapid simultaneous radioimmunoassay for triiodothyronine and thyroxine in unextracted serum
Mitsuma, T., Colucci, J., Shenkman, L., & Hollander, C. S. (1972) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(72)90766-8 · Cited by 199
Reduction in Plasma Vasopressin Levels of Dehydrated Rats Following Acute Stress
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(2004) · PubMed · Cited by 681
Touma, C., Sachser, N., Möstl, E., & Palme, R. (2003) · General and Comparative Endocrinology · doi:10.1016/s0016-6480(02)00620-2 · Cited by 581
Comparative analysis of ACTH and corticosterone sampling methods in rats
Vahl, T. P., Ulrich-Lai, Y. M., Ostrander, M. M., Dolgas, C. M., Elfers, E. E., Seeley, R. J., D'Alessio, D. A., & Herman, J. P. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00122.2005 · Cited by 304
Inoculation stress hypothesis of environmental enrichment.
Crofton, E. J., Zhang, Y., & Green, T. A. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.017 · Cited by 206
Non-invasive measurement of adrenocortical activity in male and female rats
Lepschy, M., Touma, C., Hruby, R., & Palme, R. (2007) · Laboratory Animals · doi:10.1258/002367707781282730 · Cited by 129
Metadata
- Authors
- Gärtner, K., Büttner, D., Döhler, K., Friedel, R., Lindena, J., & Trautschold, I.
- Venue
- Laboratory Animals
- Publisher
- SAGE Publications
- Published
- 1980-07-01
- Volume
- 14
- Issue
- 3
- Pages
- 267-274
- ISSN
- 0023-6772 (ISSN-L)
- 1758-1117
- OpenAlex
- W2111245372
- Cited by
- 264
- References
- 17
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gärtner, K., Büttner, D., Döhler, K., Friedel, R., Lindena, J., & Trautschold, I. (1980). Stress response of rats to handling and experimental procedures. Laboratory Animals. https://doi.org/10.1258/002367780780937454
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
