Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response

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Exploiting the DNA Damage Response for Prostate Cancer Therapy

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The Robust Lamina Cribrosa Vasculature: Perfusion and Oxygenation Under Elevated Intraocular Pressure

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Investigating Microenvironmental Regulation of Human Chordoma Cell Behaviour

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Hypoxia protects against the cell death triggered by oxovanadium–galactomannan complexes in HepG2 cells

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Setanaxib as a Potent Hypoxia-specific Therapeutic Agent Against Liver Cancer

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“Hypoxic” Silurian oceans suggest early animals thrived in a low-O2 world

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PPARγ Agonist Pioglitazone Prevents Hypoxia-induced Cardiac Dysfunction by Reprogramming Glucose Metabolism

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Bridging the gap: advancing cancer cell culture to reveal key metabolic targets

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Effects of indirect actions and oxygen on relative biological effectiveness: estimate of DSB inductions and conversions induced by therapeutic proton beams

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Biodegradable oxygen biosensors via electrospinning

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Oxygen in Metabolic Dysfunction and Its Therapeutic Relevance

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Improving the synergistic combination of programmed death‐1/programmed death ligand‐1 blockade and radiotherapy by targeting the hypoxic tumour microenvironment

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Targeting DNA topoisomerase IIα ( TOP2A ) in the hypoxic tumour microenvironment using unidirectional hypoxia‐activated prodrugs ( uHAPs )

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Blood, Toil, and Taxoteres: Biological Determinants of Treatment-Induced ctDNA Dynamics for Interpreting Tumor Response

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Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary Fibrosis

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The Challenges of O2 Detection in Biological Fluids: Classical Methods and Translation to Clinical Applications

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Cellular Invasion Assay for the Real-Time Tracking of Individual Cells in Spheroid or Tumor-like Mimics

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The unfolding story of dying tumor cells during cancer treatment

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Hypoxia effects on oncolytic virotherapy in Cancer: Friend or Foe?

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Novel Molecular Targets for Immune Surveillance of Hepatocellular Carcinoma

Guerra, P., Martini, A., Pontisso, P., & Angeli, P. (2023) · Cancers · doi:10.3390/cancers15143629 · Cited by 11

An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic

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A novel multifunctional 2-nitroimidazole-based bioreductive linker and its application in hypoxia-activated prodrugs

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The photosensitiser azure A disrupts mitochondrial bioenergetics through intrinsic and photodynamic effects

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P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers

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Monte Carlo Simulation of Double-Strand Break Induction and Conversion after Ultrasoft X-rays Irradiation

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A Prospective Investigation of Tumor Hypoxia Imaging with 68Ga-Nitroimidazole PET/CT in Patients with Carcinoma of the Cervix Uteri and Comparison with 18F-FDG PET/CT: Correlation with Immunohistochemistry

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Iron Mobilization from Ferritin in Yeast Cell Lysate and Physiological Implications

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Modeling the role of HIF in the regulation of metabolic key genes LDH and PDH: Emergence of Warburg phenotype

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Modeling Preclinical Cancer Studies under Physioxia to Enhance Clinical Translation

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Availability of Ferritin-Bound Iron to Enterobacteriaceae

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Ethnic and paleolithic diet: Where do they stand in inflammation alleviation? A discussion

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Epithelial-Mesenchymal Transition in Tumor Microenvironment Induced by Hypoxia

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Bacterial hitchhiking with drug-loaded nanoparticles as a drug delivery strategy for cancer immunotherapy

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Hyperoxygenation Ameliorates Stress-induced Neuronal and Behavioral Deficits

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Modeling hypoxia-related inflammation scenarios

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A design of experiments screen reveals that Clostridium novyi-NT spore germinant sensing is stereoflexible for valine and its analogs

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MFN2 deficiency promotes cardiac response to hypobaric hypoxia by reprogramming cardiomyocyte metabolism

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Mitochondrial Factors in the Cell Nucleus

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Oxygen/Nitric Oxide Dual-Releasing Nanozyme for Augmenting TMZ-Mediated Apoptosis and Necrosis

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The unidirectional hypoxia‐activated prodrug OCT1002 inhibits growth and vascular development in castrate‐resistant prostate tumors

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Total synthesis of BE-43547A2

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Continuous Hypoxia and Glucose Metabolism: The Effects on Gene Expression in Mcf7 Breast Cancer Cell Line

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Determining the Relative Gene Expression Level of Hypoxia Related Genes in Different Cancer Cell Lines

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A NIR fluorescent smart probe for imaging tumor hypoxia

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A Novel Analysis Method for Evaluating the Interplay of Oxygen and Ionizing Radiation at the Gene Level

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In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

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Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3

Abbattista, M. R., Ashoorzadeh, A., Guise, C. P., Mowday, A. M., Mittra, R., Silva, S., Hicks, K. O., Bull, M. R., Jackson-Patel, V., Lin, X., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14121231 · Cited by 9

Kinetically Orthogonal Probe for Simultaneous Measurement of H2S and Nitroreductase: A Refined Method to Predict the Invasiveness of Tumor Cells

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Naturally Acquired Kelch13 Mutations in Plasmodium falciparum Strains Modulate In Vitro Ring-Stage Artemisinin-Based Drug Tolerance and Parasite Survival in Response to Hyperoxia

Duffy, S., & Avery, V. M. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01282-21 · Cited by 9

Regulatory Functions of Hypoxia in Host–Parasite Interactions: A Focus on Enteric, Tissue, and Blood Protozoa

DeMichele, E., Sosnowski, O., Buret, A. G., & Allain, T. (2023) · Microorganisms · doi:10.3390/microorganisms11061598 · Cited by 11

Tumor Microenvironment‐Related Sonodynamic Therapy Mediates Tumor Therapy

Wang, X., Wang, C., Tian, H., Wu, B., & Cheng, W. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300265 · Cited by 9

Hypoxia-Associated Alternative Splicing Signature in Lung Adenocarcinoma

Xu, Z., Wei, J., Qin, F., Sun, Y., Xiang, W., Yuan, L., Qin, J., Deng, K., Zheng, T., & Li, S. (2020) · Epigenomics · doi:10.2217/epi-2020-0399 · Cited by 9

HIF1α: A Novel Biomarker with Potential Prognostic and Immunotherapy in Pan‐cancer

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Iron, Copper, and Selenium: Cancer's Thing for Redox BlingPreprint

Terzi, E. M., & Possemato, R. (2023) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041545 · Cited by 9

Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia

Wang, C., Stöckl, S., Pattappa, G., Schulz, D., Hofmann, K., Ilić, J., Reinders, Y., Bauer, R. J., Sickmann, A., & Grässel, S. (2023) · Biomedicines · doi:10.3390/biomedicines11102804 · Cited by 8

Impact of hypoxia on the molecular content of glioblastoma-derived exosomes

Giulio, S. D., Carata, E., Muci, M., Mariano, S., & Panzarini, E. (2024) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2023.52 · Cited by 10

Mechanism of Methylene Blue Inducing the Disulfide Bond Formation of Tubulin-Associated Unit Proteins

Seo, D., Huh, Y. H., Cheong, H., Kim, E., Lim, J.-S., Lee, M. J., Lee, D., & Ryu, K. (2024) · JACS Au · doi:10.1021/jacsau.4c00262 · Cited by 8

Pericytes require physiological oxygen tension to maintain phenotypic fidelity

McErlain, T., McCulla, E. C., Glass, M. J., Hillers‐Ziemer, L. E., Branco, C. M., & Murgai, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-80682-x · Cited by 11

In situ multi-modal characterization of pancreatic cancer reveals tumor cell identity as a defining factor of the surrounding microenvironment

Lyubetskaya, A., Rabe, B. A., Kavran, A. J., Bai, Y., Fisher, A., Font‐Tello, A., Lewin, A. C., Pliner, H. A., Fan, Y., Giampapa, L., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116827 · Cited by 10

Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative

Su, Q., Wu, Q., Chen, K., Wang, J., Sarwar, A., & Zhang, Y. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06950-5 · Cited by 8

Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions

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Hypoxia-driven metabolic heterogeneity and immune evasive behaviour of gastrointestinal cancers: Elements of a recipe for disaster

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13C metabolic flux analysis clarifies distinct metabolic phenotypes of cancer cell spheroid mimicking tumor hypoxia

Noguchi, S., Wakita, K., Matsuda, F., & Shimizu, H. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.07.008 · Cited by 7

Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia‐Induced Lung Injury

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Intermittent Hypoxia in Preterm Neonates and Its Effect on Neonatal Morbidity and Mortality: A Systematic Review

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The impact of cycling hypoxia on the phenotype of HPV‐positive cervical cancer cells

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Tip of the Iceberg: A New Wave of Iron–Sulfur Cluster Proteins Found in Viruses

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Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia

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Potential role of the glycolytic oscillator in acute hypoxia in tumors

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