Risk factors for depression. New evidence on selenium deficiency and depressive disorders
Open accessAbstract
OBJECTIVES: This study aims to evaluate the effect of selenium deficiency on depressive disorders with adjustment for possible confounders. Its importance among non-dietary and dietary risk factors for depression is discussed using empirical evidence. METHODS: A structural equation model was fitted using diagonally weighted least squares estimation with adjusted chi-square test statistics (WLSMV). The average daily intake of selenium and other nutrients was calculated to verify their possible association with self-reported depressive disorders. The effect of dietary patterns was adjusted for possible confounders, including the presence of chronic diseases, life problems, pain levels, physical activity, and income. The study was performed on a sample of 9,354 men and women aged 45-65 of the Polish-Norwegian Study (PONS) cohort. RESULTS: The model shows a significant effect of low selenium intake (standardized total effect of 0.133), high lipids intake (0.102) and low iron intake (0.065) on depressive disorders. Other dietary factors fail to make a significant contribution to depressive disorders, according to the model (p > 0.05). Among the considered non-dietary risk factors, home stress (0.181), pain (0.179) and low income (0.178) show a strong correlation with depression. Pain mediates a small part of the effect of morbidity (0.140). Depressive disorders are also associated with work problems (0.123) and low physical activity (0.024). CONCLUSIONS: Selenium intake is most strongly related to depression among all the dietary factors considered. In the model, the effect of dietary risk factors on depressive disorders is moderate when compared to non-dietary variables. Chronic pain, low income and morbidity are the main correlatives of depressive disorders.
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Low income is related to depressive disorders.
“Low income is also related to depressive disorders [312].”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [312]
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Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature
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- Authors
- Czaderny, K.
- Affiliations
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Corresponding author
- Czaderny, Krzysztof
- ORCID
- Czaderny, Krzysztof
- Venue
- Psychiatria Polska
- Published
- 2020-12-31
- Volume
- 54
- Issue
- 6
- Pages
- 1109-1121
- ISSN
- 0033-2674 (ISSN-L)
- 2391-5854
- OpenAlex
- W3126788720
- Cited by
- 15
- References
- 34
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 2
- FWCI
- 1.26
- Type
- journal article
- Language
- pl
- Open access
- diamond
- doi.org
- Licence
- Locations
- Psychiatria Polska (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Selenium in Biological Systems
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Keywords
- depression, depressive disorders, selenium deficiency, dietary risk factors, iron intake, dietary fat intake, chronic pain, home stress, low income, physical activity, labor problems, morbidity, middle-aged and older adults
- MeSH terms
- Adult, Aged, Depressive Disorder, Female, Humans, Male, Middle Aged, Norway, Nutritional Status, Poland, Risk Factors, Selenium, Severity of Illness Index, Trace Elements, Cohort Studies
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