The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Particulate Matter–Induced Health Effects: Who Is Susceptible?
Open accessAbstract
BACKGROUND: Epidemiological, controlled human exposure, and toxicological studies have demonstrated a variety of health effects in response to particulate matter (PM) exposure with some of these studies indicating that populations with certain characteristics may be disproportionately affected. OBJECTIVE: To identify populations potentially at greatest risk for PM-related health effects, we evaluated epidemiological studies that examined various characteristics that may influence susceptibility, while using results from controlled human exposure and toxicological studies as supporting evidence. Additionally, we formulated a definition of susceptibility, building from the varied and inconsistent definitions of susceptibility and vulnerability used throughout the literature. DATA SYNTHESIS: We evaluated recent epidemiological studies to identify characteristics of populations potentially susceptible to PM-related health effects. Additionally, we evaluated controlled human exposure and toxicological studies to provide supporting evidence. We conducted a comprehensive review of epidemiological studies that presented stratified results (e.g., < 65 vs. ≥ 65 years of age), controlled human exposure studies that examined individuals with underlying disease, and toxicological studies that used animal models of disease. We evaluated results for consistency across studies, coherence across disciplines, and biological plausibility to assess the potential for increased susceptibility to PM-related health effects in a specific population or life stage. CONCLUSIONS: We identified a diverse group of characteristics that can lead to increased risk of PM-related health effects, including life stage (i.e., children and older adults), preexisting cardiovascular or respiratory diseases, genetic polymorphisms, and low-socioeconomic status. In addition, we crafted a comprehensive definition of susceptibility that can be used to encompass all populations potentially at increased risk of adverse health effects as a consequence of exposure to an air pollutant.
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Cites
Long-term exposure to air pollution and incidence of cardiovascular events in women
Miller, K. A., Siscovick, D. S., Sheppard, L., Shepherd, K., Sullivan, J. H., Anderson, G. L., & Kaufman, J. D. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa054409 · Cited by 1,854
Kan, H., London, S. J., Chen, G., Zhang, Y., Song, G., Zhao, N., Jiang, L., & Chen, B. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10851 · Cited by 582
Association of low-level ozone and fine particles with respiratory symptoms in children with asthma
Gent, J. F. (2003) · JAMA · doi:10.1001/jama.290.14.1859 · Cited by 477
Fine particulate air pollution and mortality in nine California counties: results from CALFINE
Ostro, B., Broadwin, R., Green, S., Feng, W.-Y., & Lipsett, M. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8335 · Cited by 425 · cited 11×
“Similarly, associa tions between shortterm exposure to PM10–2.5 and nonaccidental and cardiovascular mortality were stronger among females than among males (Malig and Ostro 2009).”
BackgroundInfluentialInflammatory markers and particulate air pollution: characterizing the pathway to disease
Zeka, A., Sullivan, J. R., Vokonas, P. S., Sparrow, D., & Schwartz, J. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl132 · Cited by 205 · cited 8×
“However, additional multic ity studies revealed no evidence for increased risk of congestive heart failure (CHF) hospital admissions (Wellenius et al. 2006b) or cause specific mortality (Zeka et al. 2006b) when comparing white with other races or blacks, respectively, with shortterm PM10 exposure.”
BackgroundInfluentialChronic Exposure to Ambient Levels of Urban Particles Affects Mouse Lung Development
Mauad, T., Helena Rodriguez Ferreira Rivero, D., de Oliveira, R. C., de Faria Coimbra Lichtenfels, A. J., Guimarães, E. T., de Andre, P. A., Kasahara, D. I., de Siqueira Bueno, H. M., & Saldiva, P. H. N. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200803-436oc · Cited by 136
Liao, D., Heiss, G., Chinchilli, V. M., Duan, Y., Folsom, A. R., Lin, H.-M., & Salomaa, V. (2005) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/sj.jea.7500408 · Cited by 129 · cited 2×
“An examination of biomarkers in individuals with diabetes who were exposed to PM revealed mixed results, including an increase in von Willebrand factor (Liao et al. 2005), an increase in thiobarbituric acid but no increases in CRP or tumor necrosis factorα (Liu et al.”
Result
Cited by
Non-exhaust PM emissions from electric vehicles
Timmers, V. R. J. H., & Achten, P. A. J. (2016) · Atmospheric Environment · doi:10.1016/j.atmosenv.2016.03.017 · Cited by 601
de Bont, J., Jaganathan, S., Dahlquist, M., Persson, Å., Stafoggia, M., & Ljungman, P. (2022) · Journal of Internal Medicine · doi:10.1111/joim.13467 · Cited by 574
Indoor air pollutants in office environments: Assessment of comfort, health, and performance
Wolkoff, P. (2013) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2012.08.001 · Cited by 342
Pan, T.-L., Wang, P.-W., Aljuffali, I. A., Huang, C.-T., Lee, C.-W., & Fang, J.-Y. (2015) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2015.01.011 · Cited by 158
Early life exposure to air pollution and incidence of childhood asthma, allergic rhinitis and eczema
To, T., Zhu, J., Stieb, D., Gray, N., Fong, I., Pinault, L., Jerrett, M., Robichaud, A., Ménard, R., van Donkelaar, A., et al. (2020) · European Respiratory Journal · doi:10.1183/13993003.00913-2019 · Cited by 156
Metadata
- Authors
- Sacks, J. D., Stanek, L. W., Luben, T. J., Johns, D. O., Buckley, B. J., Brown, J. S., & Ross, M.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-04
- Volume
- 119
- Issue
- 4
- Pages
- 446-454
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2090985202
- Cited by
- 557
- References
- 7
- FWCI
- 17.16
- Type
- journal article
- Language
- en
- Open access
- gold
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- Sacks, J. D., Stanek, L. W., Luben, T. J., Johns, D. O., Buckley, B. J., Brown, J. S., & Ross, M. (2011). Particulate Matter–Induced Health Effects: Who Is Susceptible? Environmental Health Perspectives. https://doi.org/10.1289/ehp.1002255
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