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The Association between Phthalates in Dust and Allergic Diseases among Bulgarian Children

Open access
Kolarik, Barbara, Naydenov, Kiril, Larsson, Malin, Bornehag, Carl-Gustaf, Sundell, Jan·2008·Environmental Health Perspectives

Abstract

BACKGROUND: Recent studies have identified associations between the concentration of phthalates in indoor dust and allergic symptoms in the airways, nose, and skin. OBJECTIVES: Our goal was to investigate the associations between allergic symptoms in children and the concentration of phthalate esters in settled dust collected from children's homes in Sofia and Burgas, Bulgaria. METHODS: Dust samples from the child's bedroom were collected. A total of 102 children (2-7 years of age) had symptoms of wheezing, rhinitis, and/or eczema in preceding 12 months (cases), and 82 were nonsymptomatic (controls). The dust samples were analyzed for their content of dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), butyl benzyl phthalate (BBzP), di(2-ethylhexyl) phthalate (DEHP), and di-n-octyl phthalate (DnOP). RESULTS: A higher concentration of DEHP was found in homes of case children than in those of controls (1.24 vs. 0.86 mg/g dust). The concentration of DEHP was significantly associated with wheezing in the preceding 12 months (p = 0.035) as reported by parents. We found a dose-response relationship between DEHP concentration and case status and between DEHP concentration and wheezing in the preceding 12 months. CONCLUSIONS: This study shows an association between concentration of DEHP in indoor dust and wheezing among preschool children in Bulgaria.

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Metadata

Authors
Kolarik, B., Naydenov, K., Larsson, M., Bornehag, C.-G., & Sundell, J.
Venue
Environmental Health Perspectives
Published
2008-01
Volume
116
Issue
1
Pages
98-103
ISSN
  • 0091-6765 (ISSN-L)
  • 1552-9924
OpenAlex
W2134862220
Cited by
322
References
3
FWCI
9.95
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The Association between Phthalates in Dust and Allergic Diseases among Bulgarian Children. https://app.cochat.ai/papers/10.1289/ehp.10498
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Kolarik, B., Naydenov, K., Larsson, M., Bornehag, C.-G., & Sundell, J. (2008). The Association between Phthalates in Dust and Allergic Diseases among Bulgarian Children. Environmental Health Perspectives. https://doi.org/10.1289/ehp.10498

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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