The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth
Open accessAbstract
BACKGROUND: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are man-made, ubiquitous, and persistent contaminants in the environment, wildlife, and humans. Although recent studies have shown that these chemicals interfere with fetal growth in humans, the results are inconsistent. OBJECTIVES: Our goal was to investigate the correlation between relatively low levels of PFOS and PFOA in maternal serum and birth weight and birth size. METHODS: We conducted a hospital-based prospective cohort study between July 2002 and October 2005 in Sapporo, Japan. A total of 428 women and their infants were involved in the study. We obtained characteristics of the mothers and infants from self-administered questionnaire surveys and from medical records. We analyzed maternal serum samples for PFOS and PFOA by liquid chromatography-tandem mass spectrometry (LC/MS/MS). RESULTS: After adjusting for confounding factors, PFOS levels negatively correlated with birth weight [per log10 unit: beta = -148.8 g; 95% confidence interval (CI), -297.0 to -0.5 g]. In addition, analyses stratified by sex revealed that PFOS levels negatively correlated with birth weight only in female infants (per log10 unit: beta = -269.4 g; 95% CI, -465.7 to -73.0 g). However, we observed no correlation between PFOA levels and birth weight. CONCLUSION: Our results indicate that in utero exposure to relatively low levels of PFOS was negatively correlated with birth weight.
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Cites
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620
Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247
Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries
Kannan, K., Corsolini, S., Falandysz, J., Fillmann, G., Kumar, K. S., Loganathan, B. G., Mohd, M. A., Olivero, J., Wouwe, N. V., Yang, J. H., et al. (2004) · Environmental Science & Technology · doi:10.1021/es0493446 · Cited by 1,056
The toxicology of perfluorooctanoate
Kennedy, G. L., Butenhoff, J. L., Olsen, G. W., O'Connor, J. C., Seacat, A. M., Perkins, R. G., Biegel, L. B., Murphy, S. R., & Farrar, D. G. (2004) · Critical Reviews in Toxicology · doi:10.1080/10408440490464705 · Cited by 742
Subchronic Toxicity Studies on Perfluorooctanesulfonate Potassium Salt in Cynomolgus Monkeys
Seacat, A. M. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.1.249 · Cited by 564 · cited 1×
“Other than birth weight, animal studies have shown effects of PFOS and PFOA on numerous organ systems, thyroid function, endocrine system, immune function, and congenital anomalies (Chang et al. 2008; Luebker et al. 2005b; Peden-Adams et al. 2007; Seacat et al. 2002; Thibodeaux et al. 2003).”
BackgroundThibodeaux, J. R., Hanson, R. G., Rogers, J. M., Grey, B. E., Barbee, B. D., Richards, J. H., Butenhoff, J. L., Stevenson, L. A., & Lau, C. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg121 · Cited by 445
Cited by
Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)
Steenland, K., Fletcher, T., & Savitz, D. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901827 · Cited by 660
Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639
Brunn, H., Arnold, G., Körner, W., Rippen, G., Steinhäuser, K. G., & Valentin, I. (2023) · Environmental Sciences Europe · doi:10.1186/s12302-023-00721-8 · Cited by 504
Blake, B. E., & Fenton, S. E. (2020) · Toxicology · doi:10.1016/j.tox.2020.152565 · Cited by 499
Johnson, P. I., Sutton, P., Atchley, D. S., Koustas, E., Lam, J., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307893 · Cited by 449
“…et al. 2012 Monroy et al. 2008 Nolan et al. 2009 Savitz et al. 2012a Savitz et al. 2012b (study 1) Savitz et al. 2012b (study 2) Stein et al. 2009 Washino et al. 2009 Whitworth et al. 2012 Re cru itm en t s tra teg y Bli nd ing Co nfo un din g Ex po su re as se ss me nt Inc om ple te ou tco me…”
BackgroundResultInfluential
Metadata
- Authors
- Washino, N., Saijo, Y., Sasaki, S., Kato, S., Ban, S., Konishi, K., Ito, R., Nakata, A., Iwasaki, Y., Saito, K., Nakazawa, H., & Kishi, R.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-04
- Volume
- 117
- Issue
- 4
- Pages
- 660-667
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2080096071
- Cited by
- 292
- References
- 6
- FWCI
- 13.33
- Type
- journal article
- Language
- en
- Open access
- gold
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- Washino, N., Saijo, Y., Sasaki, S., Kato, S., Ban, S., Konishi, K., Ito, R., Nakata, A., Iwasaki, Y., Saito, K., Nakazawa, H., & Kishi, R. (2009). Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth. Environmental Health Perspectives. https://doi.org/10.1289/ehp.11681
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