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Cited by 77Neurobiology of Language and BilingualismStroke Rehabilitation and RecoveryAssistive Technology in Communication and Mobility

Retrospective Analysis of Outcomes from Two Intensive Comprehensive Aphasia Programs

Persad, Carol, Wozniak, Linda, Kostopoulos, Ellina·2013·Topics in Stroke Rehabilitation
DOI 10.1310/tsr2005-388
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Abstract

Positive outcomes from intensive therapy for individuals with aphasia have been reported in the literature. Little is known about the characteristics of individuals who attend intensive comprehensive aphasia programs (ICAPs) and what factors may predict who makes clinically significant changes when attending such programs. Demographic data on participants from 6 ICAPs showed that individuals who attend these programs spanned the entire age range (from adolescence to late adulthood), but they generally tended to be middle-aged and predominantly male. Analysis of outcome data from 2 of these ICAPs found that age and gender were not significant predictors of improved outcome on measures of language ability or functional communication. However, time post onset was related to clinical improvement in functional communication as measured by the Communication Activities of Daily Living, second edition (CADL-2). In addition, for one sample, initial severity of aphasia was related to outcome on the Western Aphasia Battery-Revised, such that individuals with more severe aphasia tended to show greater recovery compared to those with mild aphasia. Initial severity of aphasia also was highly correlated with changes in CADL-2 scores. These results suggest that adults of all ages with aphasia in either the acute or chronic phase of recovery can continue to show positive improvements in language ability and functional communication with intensive treatment.

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  • Age influences inter-individual variability in treated language improvement in post-stroke aphasia.

    “It is well established that inter-individual variability in TLI in post-stroke aphasia is influenced by an array of factors, including, but not limited to, age12–15, education16–19, aphasia severity11,14,15,20,21, baseline cognitive abilities13,22,23, and, specific to bPWA, bilingual language experience and language of treatment (e.g., whether therapy is delivered in L1 or L2)24,25.”

    From Machine Learning Predictions of Recovery in Bilingual Poststroke Aphasia: Aligning Insights With Clinical Evidence (2025) · cites this paper as [14]

  • Aphasia severity influences inter-individual variability in treated language improvement in post-stroke aphasia.

    “It is well established that inter-individual variability in TLI in post-stroke aphasia is influenced by an array of factors, including, but not limited to, age12–15, education16–19, aphasia severity11,14,15,20,21, baseline cognitive abilities13,22,23, and, specific to bPWA, bilingual language experience and language of treatment (e.g., whether therapy is delivered in L1 or L2)24,25.”

    From Machine Learning Predictions of Recovery in Bilingual Poststroke Aphasia: Aligning Insights With Clinical Evidence (2025) · cites this paper as [14]

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Authors
Persad, C., Wozniak, L., & Kostopoulos, E.
Affiliations
  • University of Michigan (US)
  • Dalhousie University (CA)
Venue
Topics in Stroke Rehabilitation
Publisher
Informa UK Limited
Published
2013-09
Volume
20
Issue
5
Pages
388-397
ISSN
  • 1074-9357 (ISSN-L)
  • 1945-5119
DOI
10.1310/tsr2005-388
OpenAlex
W1991363796
Cited by
77
References
35
Citations by year
2026: 5 · 2025: 5 · 2024: 4 · 2023: 10 · 2022: 8 · 2021: 11 · 2020: 6 · 2019: 7 · 2018: 6 · 2017: 5 · 2016: 4 · 2015: 4 · 2014: 1 · 2013: 1
FWCI
1.82
Type
journal article
Language
en
Open access
closed
Locations
  • Topics in Stroke Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Health Sciences › Health Professions › Occupational Therapy › Assistive Technology in Communication and Mobility
Keywords
aphasia, treatment outcomes, predictors of recovery, aphasia severity, time since onset, functional communication, language skills, Western Aphasia Battery-Revised, stroke rehabilitation
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Aphasia, Communication, Female, Humans, Language Therapy, Male, Middle Aged, Neuropsychological Tests, Quality of Life, Retrospective Studies, Treatment Outcome, Evidence-Based Medicine, Young Adult

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