Cited by 139Coffee research and impactsBlood Pressure and Hypertension StudiesCardiac electrophysiology and arrhythmias

Effect of “energy drink” consumption on hemodynamic and electrocardiographic parameters in healthy young adults

Steinke, Leah, Lanfear, David E, Dhanapal, Vishnuprabha, Kalus, James S·2009·Annals of Pharmacotherapy

Abstract

Background Energy drinks are frequently purported to improve cognitive function and concentration. However, the cardiovascular effects of these drinks have not been adequately studied. Objective To determine the cardiac effects of a commercially available, multicomponent energy drink in healthy volunteers. Methods Fifteen healthy adults were included in this prospective study. Individuals who had chronic medical conditions, were on chronic medication, or were pregnant or breast-feeding were excluded. Subjects abstained from caffeine for 48 hours prior to and during the study. In the morning on Day 1 of the study, while subjects were in a fasted state, baseline blood pressure (BP), heart rate (HR), and electrocardiographic (ECG) parameters were measured. Participants then consumed 500 mL (2 cans) of an energy drink and measurements were repeated 30 minutes, 1 hour, 2 hours, 3 hours, and 4 hours later. Participants then drank 500 mL of energy drink daily for the next 5 days. Day 1 protocol was repeated on Day 7. Results On Days 1 and 7, maximum mean systolic BP (SBP), HR, and QTc interval occurred at 4 hours. Maximum diastolic BP (DBP) occurred at 2 hours on Days 1 and 7. Within 4 hours of energy drink consumption, on Days 1 and 7, respectively, SBP increased by 7.9% (p = 0.006) and 9.6% (p Conclusions Although no significant ECG changes were observed, HR increased 5-7 beats/min and SBP increased 10 mm Hg after energy drink consumption.

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Crossref · 10.1345/aph.1l614

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  • High consumption of these supplements may lead to an increase in blood pressure by 10 mmHg and an increase in heart rate by 5-7 beats per minute, even in healthy people.

    “Moreover, high consumption of these supplements may lead to both an increase in blood pressure by 10 mmHg and an increase in heart rate by 5–7 beats per minute, even in healthy people [43].”

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Authors
Steinke, L., Lanfear, D. E., Dhanapal, V., & Kalus, J. S.
Affiliations
  • Wayne State University (US)
  • Henry Ford Hospital (US)
Venue
Annals of Pharmacotherapy
Published
2009-03-31
Volume
43
Issue
4
Pages
596-602
ISSN
  • 0012-6578 (ISSN-L)
  • 1060-0280
  • 1542-6270
OpenAlex
W2132359122
Cited by
139
References
19
Citations by year
2026: 3 · 2025: 4 · 2024: 5 · 2023: 8 · 2022: 6 · 2021: 5 · 2020: 9 · 2019: 2 · 2018: 7 · 2017: 7 · 2016: 19 · 2015: 16 · 2014: 15 · 2013: 9 · 2012: 9
FWCI
5.75
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of Pharmacotherapy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Coffee research and impacts
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
energy drinks, caffeine, cardiovascular effects, blood pressure, heart rate, QTc interval, electrocardiographic changes, hemodynamics, young adults, healthy volunteers
MeSH terms
Adult, Beverages, Blood Pressure, Caffeine, Electrocardiography, Female, Heart Rate, Humans, Male, Prospective Studies, Young Adult

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