The DOI matches its Crossref record; 113 of the 113 references it cites were found in a registry or an index.
Wound healing: The role of growth factors
Abstract
Wound healing is a complex biological process that requires cellular interactions between a variety of cells, including fibroblasts, myofibroblasts, smooth muscle cells, endothelial cells, keratinocytes and immune cells. These interactions are mediated by numerous factors such as growth factors, hormones, blood components and second messengers. Several growth factors that are released at the wound site are presumed to be necessary for wound healing. These include epidermal growth factor (EGF), fibroblast growth factor (FGF), insulin-like growth factor (IGF), keratinocyte growth factor (KGF), platelet-derived growth factor (PDGF), transforming growth factor (TGF) and vascular endothelial growth factor (VEGF). The clinical use of growth factors to stimulate the healing of wounds is currently being investigated. Several growth factors, including PDGF, FGF-2, IGF and KGF, have been used in clinical trials, and PDGF is currently approved for use in human medicine.
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Cites
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Molecular and biological properties of vascular endothelial growth factor
Ferrara, N. (1999) · Journal of Molecular Medicine · doi:10.1007/s001099900019 · Cited by 1,158
The pig as a model for human wound healing
Sullivan, T. P., Eaglstein, W. H., Davis, S. C., & Mertz, P. (2001) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.2001.00066.x · Cited by 1,091
Role of vascular endothelial growth factor in regulation of physiological angiogenesis
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GENERAL PRINCIPLES OF WOUND HEALING
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Growth factors and wound healing: Biochemical properties of growth factors and their receptors
Bennett, N. T., & Schultz, G. S. (1993) · The American Journal of Surgery · doi:10.1016/s0002-9610(05)80797-4 · Cited by 661
Large induction of keratinocyte growth factor expression in the dermis during wound healing
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Cited by
Anderberg, C., Li, H., Fredriksson, L., Andrae, J., Betsholtz, C., Li, X., Eriksson, U., & Pietras, K. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2724 · Cited by 249
Shynlova, O., Tsui, P., Jaffer, S., & Lye, S. J. (2009) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2009.02.044 · Cited by 220
Delayed Wound Healing and Epidermal Hyperproliferation in Mice Lacking JunB in the Skin
Florin, L., Knebel, J., Zigrino, P., Vonderstrass, B., Mauch, C., Schorpp-Kistner, M., Szabowski, A., & Angel, P. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700123 · Cited by 79
Nasole, E., Nicoletti, C., Yang, Z.-J., Girelli, A., Rubini, A., Giuffreda, F., Di Tano, A., Camporesi, E., & Bosco, G. (2014) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2012.759951 · Cited by 39
Metadata
- Authors
- Grazul-Bilska, A. T., Johnson, M. L., Bilski, J. J., Redmer, D. A., Reynolds, L. P., Abdullah, A., & Abdullah, K. M.
- Venue
- Drugs of Today
- Publisher
- Portico
- Published
- 2003
- Volume
- 39
- Issue
- 10
- Pages
- 787
- ISSN
- 0025-7656 (ISSN-L)
- 1699-4019
- OpenAlex
- W2079023278
- Cited by
- 255
- References
- 113
- FWCI
- 6.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Grazul-Bilska, A. T., Johnson, M. L., Bilski, J. J., Redmer, D. A., Reynolds, L. P., Abdullah, A., & Abdullah, K. M. (2003). Wound healing: The role of growth factors. Drugs of Today. https://doi.org/10.1358/dot.2003.39.10.799472
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
