The DOI matches its Crossref record.
Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics
Abstract
We have studied the optical properties of mammalian cell suspensions to provide a mechanistic basis for interpreting the optical properties of tissues in vivo. Measurements of the wavelength dependence of the reduced scattering coefficient and measurements of the phase function demonstrated that there is a distribution of scatterer sizes. The volumes of the scatterers are equivalent to those of spheres with diameters in the range between ~0.4 and 2.0 mum. Measurements of isolated organelles indicate that mitochondria and other similarly sized organelles are responsible for scattering at large angles, whereas nuclei are responsible for small-angle scattering. Therefore optical diagnostics are expected to be sensitive to organelle morphology but not directly to the size and shape of the cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Zonios, G., Bykowski, J., & Kollias, N. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01577.x · Cited by 477
Optical properties of human skin
Lister, T., Wright, P. A., & Chappell, P. H. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.9.090901 · Cited by 467
Backman, V., Gurjar, R., Badizadegan, K., Itzkan, I., Dasari, R. R., Perelman, L. T., & Feld, M. S. (1999) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/2944.796325 · Cited by 396
A review of in‐vivo optical properties of human tissues and its impact on PDT
Sandell, J. L., & Zhu, T. C. (2011) · Journal of Biophotonics · doi:10.1002/jbio.201100062 · Cited by 384
Esmonde-White, K. A., Cuellar, M., Uerpmann, C., Lenain, B., & Lewis, I. R. (2017) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-016-9824-1 · Cited by 332
Metadata
- Authors
- Mourant, J. R., Freyer, J. P., Hielscher, A. H., Eick, A. A., Shen, D., & Johnson, T. M.
- Venue
- Applied Optics
- Publisher
- Optica Publishing Group
- Published
- 1998-06-01
- Volume
- 37
- Issue
- 16
- Pages
- 3586
- ISSN
- 0003-6935 (ISSN-L)
- 1539-4522
- OpenAlex
- W2094108443
- Cited by
- 681
- References
- 0
- FWCI
- 16.72
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics. https://app.cochat.ai/papers/10.1364/ao.37.003586
- The paper
- Mourant, J. R., Freyer, J. P., Hielscher, A. H., Eick, A. A., Shen, D., & Johnson, T. M. (1998). Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics. Applied Optics. https://doi.org/10.1364/ao.37.003586
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
