The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system
Open accessAbstract
Using a hand-held photoacoustic probe integrated with a clinical ultrasound array system, we successfully imaged objects deeply positioned in biological tissues. The optical contrasts were enhanced by methylene blue with a concentration of ~30 mM. The penetration depth reached ~5.2 cm in chicken breast tissue by using 650-nm wavelength, which is ~4.7 times the 1/e optical penetration depth. This imaging depth was achieved using a laser fluence on the tissue surface of only 3 mJ/cm(2), which is 1/7 of the American National Standards Institute (ANSI) safety limit (20 mJ/cm(2)). The noise equivalent sensitivity at this depth was ~11 mM. Further, after intradermal injection of methylene blue in a rat, a sentinel lymph node was easily detected in vivo, beneath a 2-cm thick layer of chicken breast. Also, blood located 3.5 cm deep in the rat was clearly imaged with intrinsic contrast. We have photoacoustically guided insertion of a needle into a rat sentinel lymph node with accumulated methylene blue. These results highlight the clinical potential of photoacoustic image-guided identification and needle biopsy of sentinel lymph nodes for axillary staging in breast cancer patients.
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Two-photon laser scanning fluorescence microscopy
Denk, W., Strickler, J. H., & Webb, W. W. (1990) · Science · doi:10.1126/science.2321027 · Cited by 9,488
Multiscale photoacoustic microscopy and computed tomography
Wang, L. V. (2009) · Nature Photonics · doi:10.1038/nphoton.2009.157 · Cited by 1,400
Self-citationKim, C., Favazza, C., & Wang, L. V. (2010) · Chemical Reviews · doi:10.1021/cr900266s · Cited by 807
Self-citationProbing Individual Molecules with Confocal Fluorescence Microscopy
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Self-citationRetinotopic mapping of adult human visual cortex with high-density diffuse optical tomography
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Self-citationSentinel Lymph Nodes in the Rat: Noninvasive Photoacoustic and US Imaging with a Clinical US System
Erpelding, T. N., Kim, C., Pramanik, M., Jankovic, L., Maslov, K., Guo, Z., Margenthaler, J. A., Pashley, M. D., & Wang, L. V. (2010) · Radiology · doi:10.1148/radiol.10091772 · Cited by 252
Self-citationSensitivity of laser opto-acoustic imaging in detection of small deeply embedded tumors
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Cited by
Photoacoustic tomography: In vivo imaging from organelles to organs
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Self-citationPhotoacoustic clinical imaging
Steinberg, I., Huland, D. M., Vermesh, O., Frostig, H. E., Tummers, W. S., & Gambhir, S. S. (2019) · Photoacoustics · doi:10.1016/j.pacs.2019.05.001 · Cited by 553
A Gold/Silver Hybrid Nanoparticle for Treatment and Photoacoustic Imaging of Bacterial Infection
Kim, T., Zhang, Q., Li, J., Zhang, L., & Jokerst, J. V. (2018) · ACS Nano · doi:10.1021/acsnano.8b01362 · Cited by 284
Zhang, Y., Chen, R., Liu, F., Miao, P., Lin, L., & Ye, J. (2023) · Small Methods · doi:10.1002/smtd.202201334 · Cited by 52
Metadata
- Authors
- Kim, C., Erpelding, T. N., Jankovic, L., Pashley, M. D., & Wang, L. V.
- Venue
- Biomedical Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2010-07-26
- Volume
- 1
- Issue
- 1
- Pages
- 278
- ISSN
- 2156-7085 (ISSN-L)
- OpenAlex
- W1990189624
- Cited by
- 289
- References
- 14
- FWCI
- 10.38
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
