The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Three-dimensional photoacoustic imaging of blood vessels in tissue
Abstract
We applied photoacoustics as a tissue tomography technique for the detection of blood concentrations, e.g., angiogenesis around tumors. We imaged blood vessels in highly scattering samples, using 532-nm light, to depths of ~1 cm . The samples were real tissue (chicken breast) or 10% dilutions of Intralipid-10%. The blood flowed through nylon capillaries. Polyvinylidene difluoride (PVdF) piezoelectric detectors were used in a surface-scanning mode. We demonstrate the sensitivity of the technique by photoacoustic detection of single red blood cells upon a glass plate. Lateral resolution is limited by the detector diameter (200 microm). The depth resolution is ~10 microm.
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Cites
A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530
Cited by
Photoacoustic imaging in biomedicine
Xu, M., & Wang, L. V. (2006) · Review of Scientific Instruments · doi:10.1063/1.2195024 · Cited by 2,700
Tutorial on Photoacoustic Microscopy and Computed Tomography
Wang, L. V. (2008) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2007.913398 · Cited by 607
Prospects of photoacoustic tomography
Wang, L. V. (2008) · Medical Physics · doi:10.1118/1.3013698 · Cited by 561
Reconstructions in limited‐view thermoacoustic tomography
Xu, Y., Wang, L. V., Ambartsoumian, G., & Kuchment, P. (2004) · Medical Physics · doi:10.1118/1.1644531 · Cited by 398
Multifunctional nanoparticles for brain tumor imaging and therapy
Cheng, Y., Morshed, R. A., Auffinger, B., Tobias, A. L., & Lesniak, M. S. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.09.006 · Cited by 349
Metadata
- Authors
- Hoelen, C. G. A., de Mul, F. F. M., Pongers, R., & Dekker, A.
- Venue
- Optics Letters
- Publisher
- Optica Publishing Group
- Published
- 1998-04-15
- Volume
- 23
- Issue
- 8
- Pages
- 648
- ISSN
- 0146-9592 (ISSN-L)
- 1539-4794
- OpenAlex
- W2141668152
- Cited by
- 446
- References
- 1
- FWCI
- 10.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hoelen, C. G. A., de Mul, F. F. M., Pongers, R., & Dekker, A. (1998). Three-dimensional photoacoustic imaging of blood vessels in tissue. Optics Letters. https://doi.org/10.1364/ol.23.000648
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
