The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Parallel Thalamic Pathways for Whisking and Touch Signals in the Rat
Open accessAbstract
In active sensation, sensory information is acquired via movements of sensory organs; rats move their whiskers repetitively to scan the environment, thus detecting, localizing, and identifying objects. Sensory information, in turn, affects future motor movements. How this motor-sensory-motor functional loop is implemented across anatomical loops of the whisker system is not yet known. While inducing artificial whisking in anesthetized rats, we recorded the activity of individual neurons from three thalamic nuclei of the whisker system, each belonging to a different major afferent pathway: paralemniscal, extralemniscal (a recently discovered pathway), or lemniscal. We found that different sensory signals related to active touch are conveyed separately via the thalamus by these three parallel afferent pathways. The paralemniscal pathway conveys sensor motion (whisking) signals, the extralemniscal conveys contact (touch) signals, and the lemniscal pathway conveys combined whisking-touch signals. This functional segregation of anatomical pathways raises the possibility that different sensory-motor processes, such as those related to motion control, object localization, and object identification, are implemented along different motor-sensory-motor loops.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Rat Brain in Stereotaxic Coordinates
(1982) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 51,963
Gibson, J. J. (1962) · Psychological Review · doi:10.1037/h0046962 · Cited by 1,435
Hawkins, J., & Blakeslee, S. (2004) · Cited by 1,012
Functional organization of thalamocortical relays
Sherman, S. M., & Guillery, R. W. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.76.3.1367 · Cited by 760
Transformation from temporal to rate coding in a somatosensory thalamocortical pathway
Ahissar, E., Sosnik, R., & Haidarliu, S. (2000) · Nature · doi:10.1038/35018568 · Cited by 393
Self-citationThe organization of corticothalamic projections: reciprocity versus parity
Deschênes, M., Veinante, P., & Zhang, Z.-W. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00017-4 · Cited by 371
Katz, D. M., & Krueger, L. E. (1989) · Medical Entomology and Zoology · Cited by 369
Coding of somatic sensory input by vibrissae neurons in the rat's trigeminal ganglion
Zucker, E., & Welker, W. I. (1969) · Brain Research · doi:10.1016/0006-8993(69)90061-4 · Cited by 359
Brecht, M., & Sakmann, B. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.018465 · Cited by 344
Behavioral Modulation of Tactile Responses in the Rat Somatosensory System
Fanselow, E. E., & Nicolelis, M. A. L. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07603.1999 · Cited by 343
A third parallel visual pathway to primate area V1
CASAGRANDE, V (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90065-5 · Cited by 335
Diamond, M. E., Armstrong‐James, M., & Ebner, F. F. (1992) · Journal of Comparative Neurology · doi:10.1002/cne.903180410 · Cited by 318
Encoding of Vibrissal Active Touch
Szwed, M., Bagdasarian, K., & Ahissar, E. (2003) · Neuron · doi:10.1016/s0896-6273(03)00671-8 · Cited by 287
Self-citationNeuronal Encoding of Texture in the Whisker Sensory Pathway
Arabzadeh, E., Zorzin, E., & Diamond, M. E. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030017 · Cited by 278
Friedberg, M. H., Lee, S. M., & Ebner, F. F. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.5.2243 · Cited by 276
Absence of Rapid Sensory Adaptation in Neocortex during Information Processing States
Castro-Alamancos, M. A. (2004) · Neuron · doi:10.1016/s0896-6273(03)00853-5 · Cited by 228
Ahissar, E., & Arieli, A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00466-4 · Cited by 227
Self-citationLayer-Specific Somatosensory Cortical Activation During Active Tactile Discrimination
Krupa, D. J., Wiest, M. C., Shuler, M. G., Laubach, M., & Nicolelis, M. A. L. (2004) · Science · doi:10.1126/science.1093318 · Cited by 208
Parallel Streams for the Relay of Vibrissal Information through Thalamic Barreloids
Pierret, T., Lavallée, P., & Deschênes, M. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07455.2000 · Cited by 208
Bishop, G. H. (1959) · PubMed · Cited by 192
Invited Review Anatomical loops and their electrical dynamics in relation to whisking by rat
KLEINFELD, D., BERG, R. W., & O'CONNOR, S. M. (1999) · Somatosensory & Motor Research · doi:10.1080/08990229970528 · Cited by 191
Feedforward Inhibitory Control of Sensory Information in Higher-Order Thalamic Nuclei
Lavallée, P., Urbain, N., Dufresne, C., Bokor, H., Acsády, L., & Deschênes, M. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2301-05.2005 · Cited by 191
BISHOP, G. H. (1959) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-195902000-00001 · Cited by 185
Barrels and septa: Separate circuits in rat barrel field cortex
Kim, U., & Ebner, F. F. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990614)408:4<489::aid-cne4>3.0.co;2-e · Cited by 184
Land, P. W., Buffer, S. A., & Yaskosky, J. D. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903550407 · Cited by 182
Selective GABAergic Control of Higher-Order Thalamic Relays
Bokor, H., Frère, S. G. A., Eyre, M. D., Slézia, A., Ulbert, I., Lüthi, A., & Acsády, L. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.048 · Cited by 169
Responses of barrel cortex neurons in awake rats and effects of urethane anesthesia
Simons, D., Carvell, G. E., Hershey, A., & Bryant, D. P. (1992) · Experimental Brain Research · doi:10.1007/bf00231659 · Cited by 156
Thalamocortical optimization of tactile processing according to behavioral state
Nicolelis, M. A. L., & Fanselow, E. E. (2002) · Nature Neuroscience · doi:10.1038/nn0602-517 · Cited by 144
Chemically Defined Parallel Pathways in the Monkey Auditory System
Jones, E. G. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1284.033 · Cited by 141
Tracking Whisker and Head Movements in Unrestrained Behaving Rodents
Knutsen, P. M., Derdikman, D., & Ahissar, E. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00718.2004 · Cited by 138
Self-citationCastro‐Alamancos, M. A. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.013283 · Cited by 129
The thalamus as a monitor of motor outputs.
Guillery, R. W., & Sherman, S. M. (2002) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1171 · Cited by 128
Positive Feedback in a Brainstem Tactile Sensorimotor Loop
Nguyen, Q.-T., & Kleinfeld, D. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.042 · Cited by 126
Vibrissal roughness discrimination is barrelcortex-dependent
Guic-Robles, E., Jenkins, W. M., & Bravo, H. (1992) · Behavioural Brain Research · doi:10.1016/s0166-4328(05)80150-0 · Cited by 123
Frequency-Dependent Processing in the Vibrissa Sensory System
Moore, C. I. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00925.2003 · Cited by 111
Size gradients of barreloids in the rat thalamus
Haidarliu, S., & Ahissar, E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20010115)429:3<372::aid-cne2>3.0.co;2-3 · Cited by 88
Self-citationoff Responses in the Auditory Thalamus of the Guinea Pig
He, J. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00083.2002 · Cited by 86
Responses in the rat thalamus to whisker movements produced by motor nerve stimulation
Brown, A. W., & Waite, P. M. E. (1974) · The Journal of Physiology · doi:10.1113/jphysiol.1974.sp010531 · Cited by 73
Response Transformation and Receptive-Field Synthesis in the Lemniscal Trigeminothalamic Circuit
Minnery, B. S., Bruno, R. M., & Simons, D. J. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00111.2003 · Cited by 73
Metabolic and structural correlates of the vibrissae representation in the thalamus of the adult rat
Land, P. W., & Simons, D. J. (1985) · Neuroscience Letters · doi:10.1016/0304-3940(85)90597-x · Cited by 67
Differential Distribution of Burst and Single-Spike Responses in Auditory Thalamus
He, J., & Hu, B. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.4.2152 · Cited by 66
Chapter 6 Temporal and spatial coding in the rat vibrissal system
Ahissar, E., & Zacksenhouse, M. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)30007-9 · Cited by 62
Self-citationA Map of Angular Tuning Preference in Thalamic Barreloids
Timofeeva, E., Mérette, C., Émond, C., Lavallée, P., & Deschênes, M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-33-10717.2003 · Cited by 54
Cadusseau, J., & Roger, M. (1990) · PubMed · Cited by 11
Diamond, M. E. (2000) · Nature · doi:10.1038/35018663 · Cited by 9
Cited by
The subcellular organization of neocortical excitatory connections
Petreanu, L., Mao, T., Sternson, S. M., & Svoboda, K. (2009) · Nature · doi:10.1038/nature07709 · Cited by 1,047
A disinhibitory circuit mediates motor integration in the somatosensory cortex
Lee, S., Kruglikov, I., Huang, Z. J., Fishell, G., & Rudy, B. (2013) · Nature Neuroscience · doi:10.1038/nn.3544 · Cited by 758
The Functional Organization of the Barrel Cortex
Petersen, C. C. H. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.017 · Cited by 732
Active sensation: Insights from the rodent vibrissa sensorimotor system
Kleinfeld, D., Ahissar, E., & Diamond, M. E. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.06.009 · Cited by 374
Self-citationLong‐range connectivity of mouse primary somatosensory barrel cortex
Aronoff, R., Matyas, F., Mateo, C., Ciron, C., Schneider, B., & Petersen, C. C. H. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07264.x · Cited by 323
Metadata
- Authors
- Yu, C., Derdikman, D., Haidarliu, S., & Ahissar, E.
- Venue
- PLoS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2006-04-18
- Volume
- 4
- Issue
- 5
- Pages
- e124
- ISSN
- 1544-9173 (ISSN-L)
- 1545-7885
- OpenAlex
- W2049611124
- Cited by
- 260
- References
- 45
- FWCI
- 8.29
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
