Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD)
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Patients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making.However, excess caution in decision making may also lead to better performance in specific situations where the cost of extended deliberation is small.We compared 16 juvenile OCD patients with 16 matched healthy controls whilst they performed a sequential information gathering task under different external cost conditions.We found that patients with OCD outperformed healthy controls, winning significantly more points.The groups also differed in the number of draws required prior to committing to a decision, but not in decision accuracy.A novel Bayesian computational model revealed that subjective sampling costs arose as a non-linear function of sampling, closely resembling an escalating urgency signal.Group difference in performance was best explained by a later emergence of these subjective costs in the OCD group, also evident in an increased decision threshold.Our findings present a novel computational model and suggest that enhanced information gathering in OCD can be accounted for by a higher decision threshold arising out of an altered perception of costs that, in some specific contexts, may be advantageous. Author summaryPatients with obsessive-compulsive disorder (OCD) report to suffer from indecisiveness and overly cautious decision making.Although many studies captured such a bias experimentally, little is known about the cognitive mechanisms driving such an indecisiveness.In this study, we investigated 16 juvenile OCD patients and compared their performance
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The literature suggests alterations in the distinct reinforcement learning systems that underlie model-free and model-based decision-making processes in OCD, MDD, and schizophrenia.
“The literature suggests alterations in the distinct reinforcement learning systems that underlie model-free and model-based decision-making processes in OCD, MDD, and schizophrenia. 59,63,69–74”
From Investigating disorder-specific and transdiagnostic alterations in model-based and model-free decision-making (2024) · cites this paper as [71]
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- Authors
- Hauser, T. U., Moutoussis, M., Iannaccone, R., Brem, S., Walitza, S., Drechsler, R., Dayan, P., & Dolan, R. J.
- Affiliations
- Wellcome Centre for Human Neuroimaging (GB)
- University of Zurich (CH)
- Gatsby Computational Neuroscience Unit (GB)
- Corresponding author
- Hauser, Tobias U.
- ORCID
- Venue
- PLOS Computational Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2017-04-12
- Volume
- 13
- Issue
- 4
- Pages
- e1005440
- ISSN
- 1553-734X (ISSN-L)
- 1553-7358
- PMC
- PMC5406001
- OpenAlex
- W2607053545
- Cited by
- 85
- References
- 76
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 7 · 2023: 5 · 2022: 9 · 2021: 20 · 2020: 16 · 2019: 7 · 2018: 3 · 2017: 8 · 2016: 1
- FWCI
- 11.53
- Type
- journal article
- Language
- en
- Update notices
- new_version (2017-04-26)
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS Computational Biology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UCL Discovery (University College London) (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- Figshare (submittedVersion, cc-by)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Repository for Publications and Research Data (ETH Zurich) (submittedVersion, cc-by)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, cc-by)
- ETH Zürich Research Collection (cc-by)
- Zurich Open Repository and Archive (University of Zurich)
- Funders
- Wellcome Trust (098362/Z/12/Z, 095844/Z/11/Z, 091593/Z/10/Z)
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (320030_130237, 151641)
- Hartmann Muller (1460)
- Max-Planck-Gesellschaft
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Keywords
- obsessive-compulsive disorder, decision threshold, information gathering, sequential sampling, indecision, decision-making, perceived cost
- MeSH terms
- Adolescent, Bayes Theorem, Decision Making, Female, Humans, Male, Neuropsychological Tests, Obsessive-Compulsive Disorder, Risk-Taking, Models, Statistical
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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