The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Genetic Analysis of the Cytoplasmic Dynein Subunit Families
Open accessAbstract
Cytoplasmic dyneins, the principal microtubule minus-end-directed motor proteins of the cell, are involved in many essential cellular processes. The major form of this enzyme is a complex of at least six protein subunits, and in mammals all but one of the subunits are encoded by at least two genes. Here we review current knowledge concerning the subunits, their interactions, and their functional roles as derived from biochemical and genetic analyses. We also carried out extensive database searches to look for new genes and to clarify anomalies in the databases. Our analysis documents evolutionary relationships among the dynein subunits of mammals and other model organisms, and sheds new light on the role of this diverse group of proteins, highlighting the existence of two cytoplasmic dynein complexes with distinct cellular roles.
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Cites
The Molecular Motor Toolbox for Intracellular Transport
Vale, R. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00111-9 · Cited by 1,982
Complete sequencing and characterization of 21,243 full-length human cDNAs
Ota, T., Suzuki, Y., Nishikawa, T., Otsuki, T., Sugiyama, T., Irie, R., Wakamatsu, A., Hayashi, K., Sato, H., Nagai, K., et al. (2004) · Nature Genetics · doi:10.1038/ng1285 · Cited by 925
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The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly
Pazour, G. J., Dickert, B. L., & Witman, G. B. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.3.473 · Cited by 471
Martin, M., Iyadurai, S. J., Gassman, A., Gindhart, J. G., Hays, T. S., & Saxton, W. M. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.11.3717 · Cited by 365
Cytoplasmic Dynein Heavy Chain 1b Is Required for Flagellar Assembly in Chlamydomonas
Porter, M. E., Bower, R., Knott, J. A., Byrd, P., & Dentler, W. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.3.693 · Cited by 333
Cited by
Hirokawa, N., Niwa, S., & Tanaka, Y. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.039 · Cited by 1,138
Functions and mechanics of dynein motor proteins
Roberts, A. J., Kon, T., Knight, P. J., Sutoh, K., & Burgess, S. A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3667 · Cited by 537
In vitro reconstitution of a highly processive recombinant human dynein complex
Schlager, M. A., Hoang, H. T., Urnavicius, L., Bullock, S. L., & Carter, A. P. (2014) · The EMBO Journal · doi:10.15252/embj.201488792 · Cited by 351
Intraflagellar transport motors in cilia: moving along the cell's antenna
Scholey, J. M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200709133 · Cited by 272
DYNC2H1 Mutations Cause Asphyxiating Thoracic Dystrophy and Short Rib-Polydactyly Syndrome, Type III
Dagoneau, N., Goulet, M., Geneviève, D., Sznajer, Y., Martinovic, J., Smithson, S., Huber, C., Baujat, G., Flori, E., Tecco, L., et al. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.04.016 · Cited by 255
Metadata
- Authors
- Pfister, K. K., Shah, P. R., Hummerich, H., Russ, A., Cotton, J., Annuar, A. A., King, S. M., & Fisher, E. M. C.
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2006-01-27
- Volume
- 2
- Issue
- 1
- Pages
- e1
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- OpenAlex
- W2142726051
- Cited by
- 310
- References
- 6
- FWCI
- 8.49
- Type
- journal article
- Language
- en
- Open access
- gold
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- Pfister, K. K., Shah, P. R., Hummerich, H., Russ, A., Cotton, J., Annuar, A. A., King, S. M., & Fisher, E. M. C. (2006). Genetic Analysis of the Cytoplasmic Dynein Subunit Families. PLoS Genetics. https://doi.org/10.1371/journal.pgen.0020001
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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