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Mutations in Conserved Residues of the C. elegans microRNA Argonaute ALG-1 Identify Separable Functions in ALG-1 miRISC Loading and Target Repression

Zinovyeva, Anna Y., Bouasker, Samir, Simard, Martin J., Hammell, Christopher M., Ambros, Victor·2014·PLoS Genetics
DOI 10.1371/journal.pgen.1004286PMC PMC3998888
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  • In C. elegans, single amino acid substitutions within the MID (G553R) and PIWI (G716E, S895F, and S939F) domains of the miRNA Argonaute ALG-1 reverse the strand selection of certain miRNAs.

    “Consistently, in C. elegans, single amino acid substitutions within the MID (G553R) and PIWI (G716E, S895F, and S939F) domains of the miRNA Argonaute ALG‐1 (Argonaute‐like Gene) reverse the strand selection of certain miRNAs (Zinovyeva, Bouasker, Simard, Hammell, & Ambros, 2014; Zinovyeva, Veksler‐Lublinsky, Vashisht, Wohlschlegel, & Ambros, 2015).”

    From microRNA strand selection: Unwinding the rules (2021) · cites this paper as Zinovyeva et al., 2014

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Cited by

Sorted by citations

Authors
Zinovyeva, A. Y., Bouasker, S., Simard, M. J., Hammell, C. M., & Ambros, V.
Venue
PLoS Genetics
Publisher
Public Library of Science (PLoS)
Published
2014-04-24
Volume
10
Issue
4
Pages
e1004286
ISSN
1553-7404
DOI
10.1371/journal.pgen.1004286
PMC
PMC3998888
Cited by
39
References
0
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

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