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Excess of genomic defects in a woolly mammoth on Wrangel island
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Reduced genetic diversity and accumulation of numerous potentially deleterious mutations may have precipitated woolly mammoth population extinction through alteration of important functions in development, reproduction, and olfaction.
“The resulting reduced genetic diversity and the accumulation of numerous potentially deleterious mutations may have precipitated the population's extinction through the alteration of important functions in development, reproduction, and olfaction [17][18][19] .”
From Ancient DNA analysis (2021) · cites this paper as [17]
The Introduction reports an excess of putatively detrimental mutations in the pre-extinction Wrangel Island mammoth, and the Discussion says this variation may have limited survival. The Results identify affected developmental genes and olfactory receptors; the Discussion links urinary proteins to mate choice in elephants. But the paper does not establish that altered development, reproduction, or olfaction precipitated the mammoth population’s extinction, and it notes that some olfactory losses may have been nonessential or favored by island conditions. (LLM, conf=0.82)
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Revising the human mutation rate: implications for understanding human evolution
Scally, A., & Durbin, R. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3295 · Cited by 610
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Research works printed but not linked: 41
- AJ Stuart, 2004, Pleistocene to holocene extinction dynamics in giant deer and woolly mammoth, Nature, 431, 684, 10.1038/nature02890 · DOI
- D Nogués-Bravo, 2008, Climate change, humans, and the extinction of the woolly mammoth, PLoS Biol, 6, e79, 10.1371/journal.pbio.0060079 · DOI
- SL Vartanyan, 2008, Collection of radiocarbon dates on the mammoths (mammuthus primigenius) and other genera of wrangel island, northeast siberia, russia, Quaternary Research, 70, 51, 10.1016/j.yqres.2008.03.005 · DOI
- E Palkopoulou, 2015, Complete genomes reveal signatures of demographic and genetic declines in the woolly mammoth, Current Biology, 25, 1395, 10.1016/j.cub.2015.04.007 · DOI · Paper page
- M Lynch, 2006, The origins of eukaryotic gene structure, Molecular Biology and Evolution, 23, 450, 10.1093/molbev/msj050 · DOI
- A McKenna, 2010, The genome analysis toolkit: a mapreduce framework for analyzing next-generation dna sequencing data, Genome research, 20, 1297, 10.1101/gr.107524.110 · DOI · Paper page
- DW Huang, 2009, Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists, Nucleic acids research, 37, 1, 10.1093/nar/gkn923 · DOI · Paper page
- DW Huang, 2009, Systematic and integrative analysis of large gene lists using david bioinformatics resources, Nature protocols, 4, 44, 10.1038/nprot.2008.211 · DOI · Paper page
- RL Rogers, 2014, Landscape of standing variation for tandem duplications in drosophila yakuba and drosophila simulans, Molecular biology and evolution
- HM Kearney, 2001, Meiotic recombination involving heterozygous large insertions in saccharomyces cerevisiae: formation and repair of large, unpaired dna loops, Genetics, 158, 1457, 10.1093/genetics/158.4.1457 · DOI
- B Yazdanpanah, 2009, Riboflavin kinase couples tnf receptor 1 to nadph oxidase, Nature, 460, 1159, 10.1038/nature08206 · DOI
- HK Hong, 2001, The winged helix/forkhead transcription factor foxq1 regulates differentiation of hair in satin mice, Genesis, 29, 163, 10.1002/gene.1020 · DOI
- MP Verzi, 2008, Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells, Gastroenterology, 135, 591, 10.1053/j.gastro.2008.04.019 · DOI
- S Vartanyan, 1993, Holocene dwarf mammoths from wrangel island in the siberian arctic, Nature, 362, 10.1038/362337a0 · DOI
- SA Elias, 1996, Life and times of the bering land bridge, Nature, 382, 60, 10.1038/382060a0 · DOI · Paper page
- A Lozhkin, 2001, Late quaternary paleoenvironments and modern pollen data from wrangel island (northern chukotka), Quaternary Science Reviews, 20, 217, 10.1016/S0277-3791(00)00121-9 · DOI
- L Arppe, 2009, Bioapatite 87sr/86sr of the last woolly mammoths-implications for the isolation of wrangel island, Geology, 37, 347, 10.1130/G25467A.1 · DOI
- DJ Balick, 2015, Dominance of deleterious alleles controls the response to a population bottleneck, PLoS Genet, 11, e1005436, 10.1371/journal.pgen.1005436 · DOI
- P Pečnerová, 2016, Changes in variation at the mhc class ii dqa locus during the final demise of the woolly mammoth, Scientific reports, 6, 10.1038/srep25274 · DOI
- KR Thornton, 2013, Properties and modeling of gwas when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect, PLoS Genet, 9, e1003258, 10.1371/journal.pgen.1003258 · DOI
- SR Tridico, 2014, Megafaunal split ends: microscopical characterisation of hair structure and function in extinct woolly mammoth and woolly rhino, Quaternary Science Reviews, 83, 68, 10.1016/j.quascirev.2013.10.032 · DOI
- O Chernova, 2015, Architectonics of the hairs of the woolly mammoth and woolly rhino, Proceeding of the Zoological Institute RAS, 319, 441, 10.31610/trudyzin/2015.319.3.441 · DOI
- M Nei, 2008, The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity, Nature Reviews Genetics, 9, 951, 10.1038/nrg2480 · DOI
- MC Stensmyr, 2003, Evolution of the olfactory code in the drosophila melanogaster subgroup, Proceedings of the Royal Society of London B: Biological Sciences, 270, 2333, 10.1098/rspb.2003.2512 · DOI
- L Rasmussen, 2003, Olfactory adventures of elephantine pheromones, Biochemical Society Transactions, 31, 137, 10.1042/bst0310137 · DOI
- RW Graham, 2016, Timing and causes of mid-holocene mammoth extinction on st. paul island, alaska, Proceedings of the National Academy of Sciences
- L Hunter, 2007, Conserving the asiatic cheetah in iran: launching the first radio-telemetry study, Cat News, 46, 8
- X Wang, 2009, Integrating population size analysis into habitat suitability assessment: implications for giant panda conservation in the minshan mountains, china, Ecological research, 24, 1101, 10.1007/s11284-009-0589-2 · DOI
- K Guschanski, 2009, Counting elusive animals: comparing field and genetic census of the entire mountain gorilla population of bwindi impenetrable national park, uganda, Biological Conservation, 142, 290, 10.1016/j.biocon.2008.10.024 · DOI
- PS Pennings, 2006, Soft sweeps ii-molecular population genetics of adaptation from recurrent mutation or migration, Molecular biology and evolution, 23, 1076, 10.1093/molbev/msj117 · DOI
- H Li, 2009, Fast and accurate short read alignment with burrows–wheeler transform, Bioinformatics, 25, 1754, 10.1093/bioinformatics/btp324 · DOI · Paper page
- VJ Lynch, 2015, Elephantid genomes reveal the molecular bases of woolly mammoth adaptations to the arctic, Cell reports, 12, 217, 10.1016/j.celrep.2015.06.027 · DOI · Paper page
- H Li, 2009, The sequence alignment/map format and samtools, Bioinformatics, 25, 2078, 10.1093/bioinformatics/btp352 · DOI · Paper page
- YC Yao, 1988, Estimating the number of change-points via schwarz’criterion, Statistics & Probability Letters, 6, 181, 10.1016/0167-7152(88)90118-6 · DOI
- AB Olshen, 2004, Circular binary segmentation for the analysis of array-based dna copy number data, Biostatistics, 5, 557, 10.1093/biostatistics/kxh008 · DOI
- DY Chiang, 2009, High-resolution mapping of copy-number alterations with massively parallel sequencing, Nature methods, 6, 99, 10.1038/nmeth.1276 · DOI
- YS Niu, 2012, The screening and ranking algorithm to detect dna copy number variations, The annals of applied statistics, 6, 1306, 10.1214/12-AOAS539 · DOI
- PW Messer, 2013, Slim: simulating evolution with selection and linkage, Genetics, 194, 1037, 10.1534/genetics.113.152181 · DOI
- A Eyre-Walker, 2006, The distribution of fitness effects of new deleterious amino acid mutations in humans, Genetics, 173, 891, 10.1534/genetics.106.057570 · DOI · Paper page
- H Li, 2011, Inference of human population history from individual whole-genome sequences, Nature, 475, 493, 10.1038/nature10231 · DOI · Paper page
- I Barnes, 2007, Genetic structure and extinction of the woolly mammoth, mammuthus primigenius, Current Biology, 17, 1072, 10.1016/j.cub.2007.05.035 · DOI
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Orlando, L., Allaby, R., Skoglund, P., Der Sarkissian, C., Stockhammer, P. W., Ávila-Arcos, M. C., Fu, Q., Krause, J., Willerslev, E., Stone, A. C., et al. (2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-020-00011-0 · Cited by 411
Island songbirds as windows into evolution in small populations
Leroy, T., Rousselle, M., Tilak, M.-K., Caizergues, A. E., Scornavacca, C., Recuerda, M., Fuchs, J., Illera, J. C., De Swardt, D. H., Blanco, G., et al. (2021) · Current Biology · doi:10.1016/j.cub.2020.12.040 · Cited by 113
Metadata
- Authors
- Rogers, R. L., & Slatkin, M.
- ORCID
- Rogers, Rebekah L.
- Venue
- PLOS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2017-03-02
- Volume
- 13
- Issue
- 3
- Pages
- e1006601
- ISSN
- 1553-7404
- PMC
- PMC5333797
- Cited by
- 134
- References
- 1
- Language
- en
- Funders
- National Institutes of Health (US) (R01-GM40282)
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