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Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic

Lynch, Vincent J., Bedoya-Reina, Oscar C., Ratan, Aakrosh, Sulak, Michael, Drautz-Moses, Daniela I., Perry, George H., Miller, Webb, Schuster, Stephan C.·2015·Cell Reports
DOI 10.1016/j.celrep.2015.06.027

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  • Reduced genetic diversity and accumulation of numerous potentially deleterious mutations may have precipitated woolly mammoth population extinction through alteration of important functions in development, reproduction, and olfaction.

    “The resulting reduced genetic diversity and the accumulation of numerous potentially deleterious mutations may have precipitated the population's extinction through the alteration of important functions in development, reproduction, and olfaction [17][18][19] .”

    From Ancient DNA analysis (2021) · cites this paper as [18]

    The Introduction and Conclusions describe mammoth-specific genetic changes associated with Arctic adaptations, including skin and adipose development, not a genetic cause of extinction. Searches for reduced genetic diversity, deleterious mutation accumulation, reproduction, and olfaction found no passage connecting those factors to the population’s extinction in our copy. (LLM, conf=0.75)

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Metadata

Authors
Lynch, V. J., Bedoya-Reina, O. C., Ratan, A., Sulak, M., Drautz-Moses, D. I., Perry, G. H., Miller, W., & Schuster, S. C.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2015-07
Volume
12
Issue
2
Pages
217-228
ISSN
2211-1247
DOI
10.1016/j.celrep.2015.06.027
Cited by
130
References
3
Language
en
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