The DOI matches its Crossref record; 43 of the 45 references it cites were found in a registry or an index.
Characterization of Lethal Zika Virus Infection in AG129 Mice
Open accessAbstract
BACKGROUND: Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness known as Zika fever, which often is accompanied by maculopapular rash, headache, and myalgia. During the current outbreak in South America, ZIKV infection during pregnancy has been hypothesized to cause microcephaly and other diseases. The detection of ZIKV in fetal brain tissue supports this hypothesis. Because human infections with ZIKV historically have remained sporadic and, until recently, have been limited to small-scale epidemics, neither the disease caused by ZIKV nor the molecular determinants of virulence and/or pathogenicity have been well characterized. Here, we describe a small animal model for wild-type ZIKV of the Asian lineage. METHODOLOGY/PRINCIPAL FINDINGS: Using mice deficient in interferon α/β and Ɣ receptors (AG129 mice), we report that these animals were highly susceptible to ZIKV infection and disease, succumbing within seven to eight days. Rapid viremic dissemination was observed in visceral organs and brain; but only was associated with severe pathologies in the brain and muscle. Finally, these results were consistent across challenge routes, age of mice, and inoculum doses. These data represent a mouse model for ZIKV that is not dependent on adapting ZIKV to intracerebral passage in mice. CONCLUSIONS/SIGNIFICANCE: Foot pad injection of AG129 mice with ZIKV represents a biologically relevant model for studying ZIKV infection and disease development following wild-type virus inoculation without the requirement for adaptation of the virus or intracerebral delivery of the virus. This newly developed Zika disease model can be exploited to identify determinants of ZIKV virulence and reveal molecular mechanisms that control the virus-host interaction, providing a framework for rational design of acute phase therapeutics and for vaccine efficacy testing.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Although NHPs are suitable for studying ZIKV pathogenesis and therapeutics/vaccine development, they are expensive [21].”
From ICR suckling mouse model of Zika virus infection for disease modeling and drug validation (2018) · cites this paper as [21]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“AG129 and Irf3/5/7 TKO mice are the immunocompromised mice which were permissive to different strain ZIKV infection and vulnerable to ZIKV-relative pathology and lethality [10, 21, 30, 31].”
From ICR suckling mouse model of Zika virus infection for disease modeling and drug validation (2018) · cites this paper as [21]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“In this regard, small animal models are a better choice for studying ZIKV [10, 21].”
From ICR suckling mouse model of Zika virus infection for disease modeling and drug validation (2018) · cites this paper as [21]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Smithburn, K. C. (1952) · The Journal of Immunology · doi:10.4049/jimmunol.69.2.223 · Cited by 3,553
Zika Virus Outbreak on Yap Island, Federated States of Micronesia
Duffy, M. R., Chen, T.-H., Hancock, W. T., Powers, A. M., Kool, J. L., Lanciotti, R. S., Pretrick, M., Marfel, M., Holzbauer, S., Dubray, C. L., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0805715 · Cited by 3,130
Zika Virus Associated with Microcephaly
Mlakar, J., Korva, M., Tul, N., Popović, M., Poljšak-Prijatelj, M., Mraz, J., Kolenc, M., Resman Rus, K., Vesnaver Vipotnik, T., Fabjan Vodušek, V., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1600651 · Cited by 2,884
Zika Virus (I). Isolations and serological specificity
Dick, G. W. A., Kitchen, S. F., & Haddow, A. J. (1952) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(52)90042-4 · Cited by 2,698
Lanciotti, R. S., Kosoy, O. L., Laven, J. J., Velez, J. O., Lambert, A. J., Johnson, A. J., Stanfield, S. M., & Duffy, M. R. (2008) · Emerging infectious diseases · doi:10.3201/eid1408.080287 · Cited by 2,173
Biology of Zika Virus Infection in Human Skin Cells
Hamel, R., Dejarnac, O., Wichit, S., Ekchariyawat, P., Neyret, A., Luplertlop, N., Perera-Lecoin, M., Surasombatpattana, P., Talignani, L., Frédéric Thomas, A., et al. (2015) · Journal of Virology · doi:10.1128/jvi.00354-15 · Cited by 1,245
Zika Virus Outbreak, Bahia, Brazil
Campos, G. S., Bandeira, A. C., & Sardi, S. I. (2015) · Emerging infectious diseases · doi:10.3201/eid2110.150847 · Cited by 1,150
Hayes, E. B. (2009) · Emerging infectious diseases · doi:10.3201/eid1509.090442 · Cited by 889
Zika Virus, French Polynesia, South Pacific, 2013
Cao‐Lormeau, V., Roche, C., Teissier, A., Robin, E., Berry, A.-L., Mallet, H., Sall, A. A., & Musso, D. (2014) · Emerging infectious diseases · doi:10.3201/eid2006.140138 · Cited by 876
Zika virus (II). Pathogenicity and physical properties
Dick, G. W. A. (1952) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(52)90043-6 · Cited by 690
Flagged first, then by citations
2 of the 45 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 101–200 of 322
Chan, J. F., Yip, C. C., Tee, K., Zhu, Z., Tsang, J. O., Chik, K. K., Tsang, T. G., Chan, C. C., Poon, V. K., Sridhar, S., et al. (2017) · Tropical Medicine & International Health · doi:10.1111/tmi.12857 · Cited by 41
Clancy, C. S., Wettere, A. J. V., Siddharthan, V., Morrey, J. D., & Julander, J. G. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.12.019 · Cited by 41
Kato, F., Tajima, S., Nakayama, E., Kawai, Y., Taniguchi, S., Shibasaki, K.-I., Taira, M., Maeki, T., Lim, C., Takasaki, T., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-16475-2 · Cited by 40
Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice
Tsetsarkin, K. A., Maximova, O. A., Liu, G., Kenney, H., Teterina, N. L., Bloom, M. E., Grabowski, J. M., Mlera, L., Nagata, B. M., Moore, I. N., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07782-x · Cited by 40
Manet, C., Simon‐Lorière, E., Jouvion, G., Hardy, D., Prot, M., Conquet, L., Flamand, M., Panthier, J., Sakuntabhai, A., & Montagutelli, X. (2019) · Journal of Virology · doi:10.1128/jvi.01034-19 · Cited by 37
Trus, I., Udenze, D., Berube, N., Wheler, C. L., Martel, M.-J., Gerdts, V., & Karniychuk, U. U. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03077 · Cited by 43
Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection
Ding, J., Aldo, P. B., Roberts, C. M., Stabach, P. R., Liu, H., You, Y., Qiu, X., Jeong, J., Maxwell, A. J., Lindenbach, B. D., et al. (2021) · EMBO Reports · doi:10.15252/embr.202152450 · Cited by 40
Neuropathology of Zika Virus Infection
Solomon, I. H., & Milner, D. A. (2016) · Journal of Neuroinfectious Diseases · doi:10.4172/2314-7326.1000220 · Cited by 38
TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation
Zu, S., Li, C., Li, L., Deng, Y., Chen, X., Luo, D., Ye, Q., Huang, Y.-J., Li, X., Zhang, R., et al. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00872-w · Cited by 39
Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus
Olagnier, D. P., Amatore, D., Castiello, L., Ferrari, M., Palermo, E., Diamond, M., Palamara, A. T., & Hiscott, J. B. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.04.024 · Cited by 39
Purified Inactivated Zika Vaccine Candidates Afford Protection against Lethal Challenge in Mice
Baldwin, W. R., Livengood, J. A., Giebler, H. A., Stovall, J. L., Boroughs, K. L., Sonnberg, S., Bohning, K. J., Dietrich, E. A., Ong, Y. T., Danh, H. K., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-34735-7 · Cited by 40
Yu, J., Liu, X., Ke, C., Wu, Q., Lu, W., Qin, Z., He, X., Liu, Y., Deng, J., Xu, S., et al. (2017) · Viruses · doi:10.3390/v9070165 · Cited by 38
Zika virus like particles elicit protective antibodies in mice
Salvo, M. A., Kingstad-Bakke, B. A., Salas-Quinchucua, C., Camacho, E., & Osorio, J. E. (2018) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006210 · Cited by 39
Self-citationFatal Zika virus infection in the Americas: A systematic review
Cardona-Ospina, J. A., Henao-SanMartin, V., Acevedo-Mendoza, W. F., Nasner-Posso, K. M., Martínez-Pulgarín, D. F., Restrepo-López, A., Valencia-Gallego, V., Collins, M. H., & Rodriguez-Morales, A. J. (2019) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2019.08.033 · Cited by 37
Hayashida, E., Ling, Z. L., Ashhurst, T. M., Viengkhou, B., Jung, S. R., Songkhunawej, P., West, P. K., King, N. J. C., & Hofer, M. J. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1566-5 · Cited by 36
Bradley, M. P., & Nagamine, C. M. (2017) · Europe PMC (PubMed Central) · Cited by 36
Complementary Mechanisms Potentially Involved in the Pathology of Zika Virus
Ojha, C. R., Rodriguez, M., Lapierre, J., Karuppan, M. K. M., Branscome, H., Kashanchi, F., & El‐Hage, N. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02340 · Cited by 37
Macaque monkeys in Zika virus research: 1947–present
Newman, C. M., Friedrich, T. C., & O’Connor, D. H. (2017) · Current Opinion in Virology · doi:10.1016/j.coviro.2017.06.011 · Cited by 36
Interplay between Zika Virus and Peroxisomes during Infection
Wong, C. P., Xu, Z., Hou, S., Limonta, D., Kumar, A., Power, C., & Hobman, T. C. (2019) · Cells · doi:10.3390/cells8070725 · Cited by 36
Oliveira, M. B. S., Valentim, I. B., Rocha, T. S., Santos, J. C., Pires, K. S. N., Tanabe, E. L. L., Borbely, K. S. C., Borbely, A. U., & Goulart, M. O. F. (2020) · Industrial Crops and Products · doi:10.1016/j.indcrop.2020.112503 · Cited by 36
ICR suckling mouse model of Zika virus infection for disease modeling and drug validation
Wu, Y.-H., Tseng, C.-K., Lin, C.-K., Wei, C.-K., Lee, J.-C., & Young, K.-C. (2018) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0006848 · Cited by 35
Zika Virus-Mediated Death of Hippocampal Neurons Is Independent From Maturation State
Büttner, C., Heer, M., Traichel, J., Schwemmle, M., & Heimrich, B. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00389 · Cited by 35
Zika Virus Pathogenesis: A Battle for Immune Evasion
Estévez‐Herrera, J., Pérez-Yanes, S., Cabrera-Rodríguez, R., Márquez-Arce, D., Trujillo‐González, R., Machado, J. D., Madrid, R., & Valenzuela-Fernández, A. (2021) · Vaccines · doi:10.3390/vaccines9030294 · Cited by 36
Zika virus as a causative agent for primary microencephaly: the evidence so far
Tang, B. L. (2016) · Archives of Microbiology · doi:10.1007/s00203-016-1268-7 · Cited by 34
Zika virus infection and pregnancy: what we do and do not know
Ticconi, C., Pietropolli, A., & Rezza, G. (2016) · Pathogens and Global Health · doi:10.1080/20477724.2016.1234804 · Cited by 33
Rayner, J. O., Kalkeri, R., Goebel, S. J., Cai, Z., Green, B., Lin, S., Snyder, B. A., Hagelin, K., Walters, K., & Koide, F. (2018) · Viruses · doi:10.3390/v10050229 · Cited by 33
Niu, X., Zhao, L., Qu, L., Yao, Z., Zhang, F., Yan, Q., Zhang, S., Liang, R., Chen, P., Luo, J. L., et al. (2019) · Emerging Microbes & Infections · doi:10.1080/22221751.2019.1614885 · Cited by 33
Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis
Vue, D., & Tang, Q. (2021) · Zoonoses · doi:10.15212/zoonoses-2021-0017 · Cited by 36
Baldon, L., de Mendonça, S. F., Ferreira, F. V., Rezende, F. O., Amadou, S. C. G., Leite, T. H. J. F., Rocha, M. N., Marques, J. T., Moreira, L. A., & Ferreira, Á. (2022) · Pathogens · doi:10.3390/pathogens11080879 · Cited by 33
Research and development of Zika virus vaccines
Dawes, B. E., Smalley, C. A., Tiner, B. L., Beasley, D. W. C., Milligan, G. N., Reece, L. M., Hombach, J., & Barrett, A. D. T. (2016) · npj Vaccines · doi:10.1038/npjvaccines.2016.7 · Cited by 31
Host-Virus Interaction of ZIKA Virus in Modulating Disease Pathogenesis
Routhu, N. K., & Byrareddy, S. N. (2017) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-017-9736-7 · Cited by 30
Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics
McArthur, M. A. (2017) · Viruses · doi:10.3390/v9060143 · Cited by 31
Zika virus-induced acute myelitis and motor deficits in adult interferon αβ/γ receptor knockout mice
Zukor, K., Wang, H., Siddharthan, V., Julander, J. G., & Morrey, J. D. (2018) · Journal of NeuroVirology · doi:10.1007/s13365-017-0595-z · Cited by 33
Wang, R., Liao, X., Fan, D., Wang, L., Song, J., Feng, K., Li, M., Wang, P., Chen, H., & An, J. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.04.051 · Cited by 31
Tsetsarkin, K. A., Acklin, J. A., Liu, G., Kenney, H., Teterina, N. L., Pletnev, A. G., & Lim, J. K. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008601 · Cited by 31
Enlow, W., Bordeleau, M., Piret, J., Ibáñez, F. G., Uyar, O., Venable, M.-C., Goyette, N., Carbonneau, J., Tremblay, M., & Boivin, G. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02221-z · Cited by 31
A natural polymorphism in Zika virus NS2A protein responsible of virulence in mice
Ávila‐Pérez, G., Nogales, A., Park, J.-G., Márquez-Jurado, S., Iborra, F. J., Almazán, F., & Martínez‐Sobrido, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-56291-4 · Cited by 31
Overview on the Current Status of Zika Virus Pathogenesis and Animal Related Research
Pawitwar, S. S., Dhar, S., Tiwari, S., Ojha, C. R., Lapierre, J., Martins, K., Rodzinski, A., Parira, T., Paudel, I., Li, J., et al. (2017) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-017-9743-8 · Cited by 30
Zika virus: from an obscurity to a priority
Lee, C. Y., & Ng, L. F. P. (2018) · Microbes and Infection · doi:10.1016/j.micinf.2018.02.009 · Cited by 31
Vannice, K., Giersing, B. K., Kaslow, D. C., Griffiths, E., Meyer, H. L., Barrett, A. D. T., Durbin, A. P., Wood, D., & Hombach, J. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.10.034 · Cited by 29
Kawiecki, A. B., Mayton, E. H., Dutuze, M. F., Goupil, B. A., Langohr, I. M., Piero, F. D., & Christofferson, R. C. (2017) · Virology Journal · doi:10.1186/s12985-017-0749-x · Cited by 29
Animal Models for Dengue and Zika Vaccine Development
dos Santos, E. A., & Fink, K. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-8727-1_16 · Cited by 29
Consequences of in utero exposure to Zika virus in offspring of AG129 mice
Julander, J. G., Siddharthan, V., Park, A. H., Preston, E., Mathur, P. D., Bertolio, M., Wang, H., Zukor, K., Wettere, A. J. V., Sinex, D. G., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-27611-x · Cited by 29
Zika virus induces astrocyte differentiation in neural stem cells
Lossia, O. V., Conway, M. J., Tree, M. O., Williams, R. J. P., Goldthorpe, S. C., Srinageshwar, B., Dunbar, G. L., & Rossignol, J. (2017) · Journal of NeuroVirology · doi:10.1007/s13365-017-0589-x · Cited by 28
Khaiboullina, S. F., Uppal, T., Kletenkov, K., Jeor, S. C. S., Garanina, E. E., Rizvanov, A. A., & Verma, S. C. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00642 · Cited by 28
Zika Virus: Emergence, Phylogenetics, Challenges, and Opportunities
Rajah, M. M., Pardy, R. D., Condotta, S. A., Richer, M. J., & Sagan, S. M. (2016) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.6b00161 · Cited by 27
Erythromycin Estolate Inhibits Zika Virus Infection by Blocking Viral Entry as a Viral Inactivator
Wang, X., Xia, S., Zou, P., & Lu, L. (2019) · Viruses · doi:10.3390/v11111064 · Cited by 27
Wen, F., Armstrong, N., Hou, W., Cruz‐Cosme, R., Obwolo, L. A., Ishizuka, K., Ullah, H., Luo, M., Sawa, A., & Tang, Q. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.010973 · Cited by 24
Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection
Turner, L. H., Kinder, J. M., Wilburn, A. N., D'Mello, R. J., Braunlin, M. R., Jiang, T. T., Pham, G. H., & Way, S. S. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006684 · Cited by 26
In utero infection of Zika virus leads to abnormal central nervous system development in mice
Zhang, W., Tan, Y. W., Yam, W. K., Tu, H., Qiu, L., Tan, E. K., Chu, J. J. H., & Zeng, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-43303-6 · Cited by 26
Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models
Yang, D., 武汉430071，中国, 中., Li, X., Tu, D.-Z., Li, X., Wei, B., 200444，中国, 上., 200031，中国, 中., 兰州730030，中国, 兰., & 200444，中国, 上. (2023) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2023.025 · Cited by 27
Khoshmanesh, A., Christensen, D., Pérez-Guaita, D., Iturbe‐Ormaetxe, I., O’Neill, S. L., McNaughton, D., & Wood, B. R. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04827 · Cited by 26
Taking the defensive: Immune control of Zika virus infection
Bowen, J. R., Zimmerman, M. G., & Suthar, M. S. (2017) · Virus Research · doi:10.1016/j.virusres.2017.08.018 · Cited by 26
Zika virus infection confers protection against West Nile virus challenge in mice
Vázquez-Calvo, Á., Blázquez, A.-B., Escribano-Romero, E., Merino-Ramos, T., Sáiz, J., Martín-Acebes, M. A., & de Oya, N. J. (2017) · Emerging Microbes & Infections · doi:10.1038/emi.2017.68 · Cited by 25
Fibroblast Growth Factor 2 Enhances Zika Virus Infection in Human Fetal Brain
Limonta, D., Jovel, J., Kumar, A., Lu, J., Hou, S., Airo, A. M., López-Orozco, J., Wong, C. P., Saito, L. B., Branton, W. G., et al. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz073 · Cited by 26
A ‘Furry-Tale’ of Zika Virus Infection: What Have We Learned from Animal Models?
Nazerai, L., Christensen, J. P., & Thomsen, A. R. (2019) · Viruses · doi:10.3390/v11010029 · Cited by 26
Arboviruses and Muscle Disorders: From Disease to Cell Biology
Filippone, C., Legros, V., Jeannin, P., Choumet, V., Butler-Browne, G. S., Zoladek, J., Mouly, V., Antoine Gessain, A., & Ceccaldi, P. (2020) · Viruses · doi:10.3390/v12060616 · Cited by 27
Current Progress in the Development of Zika Virus Vaccines
Zhou, K., Li, C., Shi, W., Hu, X., Nandakumar, K. S., Jiang, S., & Zhang, N. (2021) · Vaccines · doi:10.3390/vaccines9091004 · Cited by 26
Small-Animal Models of Zika Virus
Julander, J. G., & Siddharthan, V. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix465 · Cited by 25
Understanding the Pathogenesis of Zika Virus Infection Using Animal Models
Krause, K. K., Azouz, F., Shin, O. S., & Kumar, M. (2017) · Immune Network · doi:10.4110/in.2017.17.5.287 · Cited by 22
Zika Virus: Immune Evasion Mechanisms, Currently Available Therapeutic Regimens, and Vaccines
Asif, A., Manzoor, S., Tuz-Zahra, F., Saalim, M., Ashraf, M., Mirza, J. I. A., & Khalid, M. (2017) · Viral Immunology · doi:10.1089/vim.2017.0046 · Cited by 24
Razak, M. R. M. A., Misnan, N. M., Jelas, N. H. M., Norahmad, N. A., Muhammad, A., Ho, T. C. D., Jusoh, B., Sastu, U. R., Zainol, M., Wasiman, M. I., et al. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2390-7 · Cited by 24
Zika virus infection and implications for kidney disease
Alcendor, D. J. (2018) · Journal of Molecular Medicine · doi:10.1007/s00109-018-1692-z · Cited by 23
Chai, C., Palinski, R. M., Xu, Y., Wang, Q., Cao, S., Geng, Y., Zhao, Q., Wen, Y., Huang, X., Yan, Q., et al. (2019) · Viruses · doi:10.3390/v11010087 · Cited by 23
Differentiation-dependent susceptibility of human muscle cells to Zika virus infection
Legros, V., Jeannin, P., Burlaud‐Gaillard, J., Chaze, T., Gianetto, Q. G., Butler-Browne, G. S., Mouly, V., Zoladek, J., Afonso, P. V., Gonzàlez, M.-N., et al. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008282 · Cited by 23
Gasco, S., & Muñoz‐Fernández, M. Á. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010035 · Cited by 23
Krauer, F., Riesen, M., Revéiz, L., Oladapo, O. T., Martínez-Vega, R. A., Porgo, T. V., Haefliger, A., Broutet, N. J. N., Low, N. N., & for the WHO Zika Causality Working Group (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/073098 · Cited by 23
AgBR1 and NeSt1 antisera protect mice from Aedes aegypti-borne Zika infection
Marín-López, A., Wang, Y., Jiang, J., Ledizet, M., & Fikrig, E. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.01.072 · Cited by 21
[18F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus-Infected Mice
Kuszpit, K. K., Hollidge, B. S., Zeng, K. X., Stafford, R. G., Daye, S. P., Zhang, X., Basuli, F., Golden, J. W., Swenson, R. E., Smith, D. R., et al. (2017) · Molecular Imaging and Biology · doi:10.1007/s11307-017-1118-2 · Cited by 21
Lethal Zika Virus Disease Models in Young and Older Interferon α/β Receptor Knock Out Mice
Marzi, A., Emanuel, J., Callison, J. A., McNally, K. L., Arndt, N., Chadinha, S., Martellaro, C., Rosenke, R., Scott, D. P., Safronetz, D., et al. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00117 · Cited by 22
Detection of Zika virus in mouse mammary gland and breast milk
Regla-Nava, J. Á., Viramontes, K. M., Vozdolska, T., Huynh, A.-T., Villani, T. S., Gardner, G., Johnson, M., Ferro, P. J., Shresta, S., & Kim, K. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007080 · Cited by 21
Li, S., Armstrong, N., Zhao, H., Cruz‐Cosme, R., Yang, H.-W., Zhong, C., Fu, W., Wang, W., Yang, D., Xia, N., et al. (2022) · Journal of Virology · doi:10.1128/jvi.01373-22 · Cited by 20
Zika Virus Neuropathogenesis—Research and Understanding
Metzler, A. D., & Tang, H. (2024) · Pathogens · doi:10.3390/pathogens13070555 · Cited by 21
Yun, S.-I., Song, B.-H., Frank, J. C., Julander, J. G., Olsen, A. L., Polejaeva, I. A., Davies, C. J., White, K. L., & Lee, Y.-M. (2018) · Viruses · doi:10.3390/v10080422 · Cited by 19
Yin, Y., Xu, Y., Su, L., Zhu, X., Chen, M., Zhu, W., Xia, H., Huang, X., & Gong, S. (2016) · Emerging Microbes & Infections · doi:10.1038/emi.2016.100 · Cited by 19
Update on the Animal Models and Underlying Mechanisms for ZIKV-Induced Microcephaly
Xu, D., Li, C., Qin, C., & Xu, Z. (2019) · Annual Review of Virology · doi:10.1146/annurev-virology-092818-015740 · Cited by 19
Wang, T., Li, P., Zhang, Y., Liu, Y., Tan, Z., Sun, J., Ke, X., Miao, Y., Luo, D., Hu, Q., et al. (2020) · Theranostics · doi:10.7150/thno.43177 · Cited by 19
Running interference: Interplay between Zika virus and the host interferon response
Pardy, R. D., Valbon, S. F., & Richer, M. J. (2019) · Cytokine · doi:10.1016/j.cyto.2019.02.009 · Cited by 18
Zika virus infection causes widespread damage to the inner ear
Yee, K. T., Neupane, B., Bai, F., & Vetter, D. E. (2020) · Hearing Research · doi:10.1016/j.heares.2020.108000 · Cited by 18
Characterization of the contemporary Zika virus in immunocompetent mice
Zhang, N., Tian, M., Deng, Y., Hao, J., Wang, H.-J., Huang, X., Li, X., Wang, Y., Zhao, L., Zhang, F., et al. (2016) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2016.1219004 · Cited by 17
Victorio, C. B. L., Novera, W., Ganasarajah, A., Ong, J., Thomas, M., Wu, J., Toh, H. S. Y., Sun, A. X., Ooi, E. E., & Chacko, A. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-04930-4 · Cited by 17
Morrey, J. D., de Oliveira, A. L. R., Wang, H., Zukor, K., de Castro, M. V., & Siddharthan, V. (2019) · Scientific Reports · doi:10.1038/s41598-019-55717-3 · Cited by 17
Host genetic control of mosquito-borne Flavivirus infections
Manet, C., Roth, C., Tawfik, A., Cantaert, T., Sakuntabhai, A., & Montagutelli, X. (2018) · Mammalian Genome · doi:10.1007/s00335-018-9775-2 · Cited by 19
Single Amino Acid Mutations Affect Zika Virus Replication In Vitro and Virulence In Vivo
Collette, N. M., Lao, V., Weilhammer, D. R., Zingg, B. C., Cohen, S. D., Hwang, M. S., Coffey, L. L., Grady, S. L., Zemla, A. T., & Borucki, M. K. (2020) · Viruses · doi:10.3390/v12111295 · Cited by 17
Elliott, K. C., & Mattapallil, J. J. (2024) · Pathogens · doi:10.3390/pathogens13020177 · Cited by 20
Using immunocompromised mice to identify mechanisms of Zika virus transmission and pathogenesis
Winkler, C. W., & Peterson, K. E. (2017) · Immunology · doi:10.1111/imm.12883 · Cited by 15
Alves, M. P., Vielle, N. J., Thiel, V., & Pfaender, S. (2018) · Viruses · doi:10.3390/v10110593 · Cited by 16
Attenuation of Zika Virus by Passage in Human HeLa Cells
Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N., & Sarathy, V. V. (2019) · Vaccines · doi:10.3390/vaccines7030093 · Cited by 16
Abdelbasset, M., Saron, W. A. A., Ma, D., Rathore, A. P. S., Kozaki, T., Zhong, C., Mantri, C. K., Tan, Y., Tung, C.-C., Tey, H. L., et al. (2024) · Cell · doi:10.1016/j.cell.2024.10.028 · Cited by 16
Luo, D., Miao, Y., Ke, X., Tan, Z., Hu, C., Li, P., Wang, T., Zhang, Y., Sun, J., Liu, Y., et al. (2020) · Virologica Sinica · doi:10.1007/s12250-020-00238-x · Cited by 16
Pletnev, A. G., Maximova, O. A., Liu, G., Kenney, H., Nagata, B. M., Zagorodnyaya, T. A., Moore, I. N., Chumakov, K., & Tsetsarkin, K. A. (2021) · Nature Communications · doi:10.1038/s41467-021-22729-5 · Cited by 14
Zika in the Brain: New Models Shed Light on Viral Infection
Hickman, H. D., & Pierson, T. C. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.06.004 · Cited by 15
Altered vector competence in an experimental mosquito-mouse transmission model of Zika infection
Uraki, R., Hastings, A. K., Gloria‐Soria, A., Powell, J. R., & Fikrig, E. (2018) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006350 · Cited by 15
How myeloid cells contribute to the pathogenesis of prominent emerging zoonotic diseases
Supramaniam, A., Lui, H., Bellette, B., Rudd, P. A., & Herrero, L. J. (2018) · Journal of General Virology · doi:10.1099/jgv.0.001024 · Cited by 15
Carbaugh, D. L., Zhou, S., Sanders, W., Moorman, N. J., Swanstrom, R. I., & Lazear, H. M. (2020) · Journal of Virology · doi:10.1128/jvi.00618-20 · Cited by 15
Establishment of a lethal mouse model of emerging tick-borne orthonairovirus infections
Ariizumi, T., Tabata, K., Itakura, Y., Kobayashi, H., Hall, W. W., Sasaki, M., Sawa, H., Matsuno, K., & Orba, Y. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012101 · Cited by 14
Tai, W., Voronin, D., Chen, J., Bao, W., Kessler, D. A., Shaz, B. H., Jiang, S., Yazdanbakhsh, K., & Du, L. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00029 · Cited by 15
Kublin, J. L., & Whitney, J. B. (2017) · Virus Research · doi:10.1016/j.virusres.2017.07.025 · Cited by 14
Zika virus reservoirs: Implications for transmission, future outbreaks, drug and vaccine development
Kalkeri, R., & Murthy, K. K. (2017) · F1000Research · doi:10.12688/f1000research.12695.1 · Cited by 13
Piret, J., Carbonneau, J., Rhéaume, C., Baz, M., & Boivin, G. (2018) · Journal of General Virology · doi:10.1099/jgv.0.000992 · Cited by 13
Metadata
- Authors
- Aliota, M. T., Caine, E. A., Walker, E. C., Larkin, K. E., Camacho, E., & Osorio, J. E.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Osorio, Jorge E.
- Venue
- PLoS neglected tropical diseases
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-04-19
- Volume
- 10
- Issue
- 4
- Pages
- e0004682
- ISSN
- 1935-2727 (ISSN-L)
- 1935-2735
- PMC
- PMC4836712
- OpenAlex
- W2338703441
- Cited by
- 322
- References
- 45
- Citations by year
- 2026: 10 · 2025: 12 · 2024: 16 · 2023: 19 · 2022: 19 · 2021: 25 · 2020: 28 · 2019: 37 · 2018: 50 · 2017: 63 · 2016: 42
- FWCI
- 63.46
- Type
- journal article
- Language
- en
- Update notices
- correction (2016-05-23)
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS neglected tropical diseases (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Repositorio Institucional Universidad de Sucre (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institute of Allergy and Infectious Diseases (R21 AI117413-01, T32AI055397)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Mosquito-borne diseases and control
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Vectors
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- Zika virus, AG129 mice, virulence factors, viremia, neuropathology, muscle pathology, mosquito-borne arboviruses, vaccine efficacy evaluation, microcephaly
- MeSH terms
- Zika Virus Infection, Interferon gamma Receptor, Animals, Brain, Death, Disease Models, Animal, Muscles, Viremia, Receptors, Interferon, Mice, Knockout, Mice, Receptor, Interferon alpha-beta
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
