miR-132 Mediates the Integration of Newborn Neurons into the Adult Dentate Gyrus
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miR-132 is most highly expressed in mature neurons.
“These miRNAs include miR-132, which is most highly expressed in mature neurons, and miR-137, which inhibits synaptic integration and dendritic spine growth when knocked down [12, 13].”
From MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. (2017) · cites this paper as [13]
miR-137 inhibits synaptic integration and dendritic spine growth when knocked down.
“These miRNAs include miR-132, which is most highly expressed in mature neurons, and miR-137, which inhibits synaptic integration and dendritic spine growth when knocked down [12, 13].”
From MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. (2017) · cites this paper as [13]
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Cites
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“MicroRNAs are endogenously expressed ,22 nucleotide RNAs, which downregulate the expression of large numbers of target genes in vivo [14,15].”
BackgroundNeural consequences of enviromental enrichment
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Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
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GABA depolarization is required for experience-dependent synapse unsilencing in adult-born neurons
Chancey, J. H., Adlaf, E. W., Sapp, M. C., Pugh, P. C., Wadiche, J. I., & Overstreet-Wadiche, L. S. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.0781-13.2013 · Cited by 152 · see citing works
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MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation.
Howe, J. R., Li, E. S., Streeter, S. E., Rahme, G. J., Chipumuro, E., Russo, G. B., Litzky, J. F., Hills, L. B., Rodgers, K. R., Skelton, P. D., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177661 · Cited by 41 · see citing works
Self-citationPenning, A., Snoeck, S., Ormaechea, O. R., Ayyildiz, D., Polzer, O., Buitrago-Arango, M., Capobianco, R., de Winter, F., Balusu, S., Verhaagen, J., et al. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-026-02228-8 · Cited by 6 · see citing works
- Authors
- Luikart, B. W., Bensen, A. L., Washburn, E. K., Perederiy, J. V., Su, K. G., Li, Y., Kernie, S. G., Parada, L. F., & Westbrook, G. L.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-05-17
- Volume
- 6
- Issue
- 5
- Pages
- e19077
- ISSN
- 1932-6203
- PMC
- PMC3096628
- Cited by
- 125
- References
- 8
- Language
- en
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